Device for uniformly mixing and stirring viral protein and adjuvant
By designing a mixing and stirring device with adjuvant containing a base, bracket, storage cylinder, piston and hydraulic cylinder, the problem of disassembly of traditional devices is solved, and efficient mixing operation without disassembly is achieved, and working efficiency is improved and reduce labor intensity.
Patent Information
- Application Number
- CN202420766895.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-15
- Publication Date
- 2024-12-06
- Estimated Expiration
- 2034-04-15
AI Technical Summary
Traditional viral protein and adjuvant mixing devices require disassembly of the container cylinder and piston when adding or removing raw materials, resulting in cumbersome operation, reducing work efficiency and increasing labor intensity.
A mixing and stirring device for viral protein and adjuvants is designed, using a base, bracket, container cylinder, piston, turntable, communication pipe and hydraulic cylinder. By controlling the rotary rotary and hydraulic cylinder, it can be realized without disassembly. Adding and removing materials simplify the operation process.
It improves work efficiency, reduces labor intensity, and simplifies operating steps, making the mixing process of viral proteins and adjuvants more convenient and efficient.
Smart Images
Figure CN222111647U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of mixing equipment, and specifically relates to a mixing and stirring device for virus protein and adjuvant. Background Art
[0002] In the vaccine preparation process, the mixing of viral protein and adjuvant is a key step. Traditional mixing devices often use two linear motors. The output shaft of one linear motor pushes out and the output shaft of the other linear motor retracts. The two pistons slide back and forth inside the two containing cylinders. The liquid repeatedly passes through the shear hole and collides with the shear plate to promote emulsification and mix the viral protein and adjuvant.
[0003] However, in the process of adding raw materials to the containing cylinder or extracting the mixed liquid, the two containing cylinders need to be disassembled each time and the piston needs to be taken out. Such operation steps are quite cumbersome, which not only makes the process of adding and removing materials more troublesome, but also significantly reduces work efficiency and increases unnecessary time cost and manpower investment. Utility Model Content
[0004] The purpose of the utility model is to provide a viral protein and adjuvant mixing and stirring device, which has a simple structure and is easy to operate. No matter taking or discharging materials, the two containing cylinders or pistons do not need to be disassembled, which improves work efficiency and effectively reduces labor intensity.
[0005] The technical solutions adopted in this utility are as follows:
[0006] A viral protein and adjuvant mixing and stirring device comprises a base, a bracket is provided on one side of the top of the base, a first accommodating cylinder is provided on one side of the bracket, a first piston is slidably and sealingly installed inside the first accommodating cylinder, a feeding hole is provided on one side of the top of the first piston, a sealing plug is provided inside the feeding hole, a first push rod is fixed on the top of the first piston and located on one side of the feeding hole, a turntable is rotatably and sealingly installed on the bottom of the first accommodating cylinder, a first connecting tube is fixedly penetrated on one side of the bottom of the turntable, a second accommodating cylinder is provided on one side of the bracket and located below the first connecting tube, a second connecting tube is fixedly penetrated on one side of the top of the second accommodating cylinder, a connecting tube is slidably installed on the outer wall of the second connecting tube corresponding to the first connecting tube, and the bottom of the first connecting tube is inserted into the connecting tube and connected with the second connecting tube, a spring is fixed on the bottom of the connecting tube, and the bottom end of the spring is fixed on the top of the second connecting tube, a second piston is slidably and sealingly installed on the inside of the second accommodating cylinder, and a second push rod is fixed on the bottom of the second piston.
[0007] Furthermore, a shear plate is provided on the inner wall of the second connecting pipe, and a shear hole is formed through the outer wall of the shear plate.
[0008] Furthermore, the inner wall of the connecting pipe is provided with two sealing rings which are in contact with the outer walls of the first connecting pipe and the second connecting pipe respectively.
[0009] Furthermore, two hydraulic cylinders are arranged on the outer wall of the bracket, and the output shafts of the two hydraulic cylinders are fixed with push plates which can push the first push rod and the second push rod to move.
[0010] Furthermore, the inner walls of the first accommodating tube and the second accommodating tube are both provided with limiting rings capable of limiting the positions of the first piston and the second piston.
[0011] The technical effects achieved by this utility model are:
[0012] The utility model discloses a virus protein and adjuvant mixing and stirring device. A feeding hole is provided on the first piston, and the feeding hole is sealed with a sealing plug, so that raw materials of virus protein and adjuvant are conveniently added into the first containing tube. A turntable is arranged, and when the connecting tube is separated from the first connecting tube, the turntable can be rotated to rotate the first connecting tube to one side, and then the first piston is driven to move downward by the retraction of the hydraulic cylinder, so that the solution in the first containing tube is discharged from the first connecting tube. The structure is simple and the operation is convenient. No matter taking or discharging materials, the two containing tubes or pistons do not need to be disassembled, so the working efficiency is improved and the labor intensity is effectively reduced. BRIEF DESCRIPTION OF THE DRAWINGS
[0013] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model;
[0014] Figure 2 It is a side-view stereoscopic structural schematic diagram of the utility model;
[0015] Figure 3 It is a schematic diagram of the partial cutaway structure of the utility model.
[0016] In the accompanying drawings, the components represented by the reference numerals are listed as follows:
[0017] 1. Base; 2. Bracket; 3. First accommodating cylinder; 4. First piston; 5. Feeding hole; 6. Sealing plug; 7. First push rod; 8. Turntable; 9. First connecting pipe; 10. Second accommodating cylinder; 11. Second connecting pipe; 12. Connecting pipe; 13. Spring; 14. Second piston; 15. Second push rod; 16. Hydraulic cylinder; 17. Push plate; 18. Limiting ring; 19. Scale line; 20. Shear plate; 21. Sealing ring. DETAILED DESCRIPTION
[0018] In order to make the purpose and advantages of the present invention more clearly understood, the present invention is specifically described below in conjunction with the embodiments. It should be understood that the following text is only used to describe one or several specific implementations of the present invention, and does not strictly limit the scope of protection specifically requested by the present invention.
[0019] like Figure 1-3 As shown, a viral protein and adjuvant mixing and stirring device comprises a base 1, a bracket 2 is arranged on one side of the top of the base 1, a first accommodating tube 3 is arranged on one side of the bracket 2, a first piston 4 is slidably and sealingly mounted inside the first accommodating tube 3, a feeding hole 5 is opened on one side of the top of the first piston 4, a sealing plug 6 is arranged inside the feeding hole 5, the sealing plug 6 is screwed and fixed to the feeding hole 5, a first push rod 7 is fixed on the top of the first piston 4 and on one side of the feeding hole 5, a turntable 8 is rotatably and sealingly mounted on the bottom of the first accommodating tube 3, a first connecting tube 9 is fixedly penetrated on one side of the bottom of the turntable 8, a second accommodating tube 10 is arranged on one side of the bracket 2 and below the first connecting tube 9, a second connecting tube 11 is fixedly penetrated on one side of the top of the second accommodating tube 10, and the outer wall of the second connecting tube 11 corresponds to the first connecting tube 9 is slidably installed with a connecting pipe 12, and the bottom of the first connecting pipe 9 is inserted into the connecting pipe 12 and connected with the second connecting pipe 11, a spring 13 is fixed at the bottom of the connecting pipe 12, and the bottom end of the spring 13 is fixed to the top of the second connecting pipe 11, and the second piston 14 is slidably installed inside the second accommodating tube 10, and a second push rod 15 is fixed at the bottom of the second piston 14, and raw materials can be added into the first accommodating tube 3 through the feeding hole 5. After the mixing is completed, the connecting pipe 12 is separated from the first connecting pipe 9, and the turntable 8 is rotated to rotate the first connecting pipe 9 to one side, and then the first piston 4 on the first push rod 7 is pushed to move through the hydraulic cylinder 16 and the push plate 17 to squeeze out the mixed liquid in the first accommodating tube 3. The operation is smooth and convenient, which is not only convenient for adding materials, but also convenient for taking materials, which greatly improves the work efficiency;
[0020] like Figure 3 As shown, the inner wall of the second connecting tube 11 is provided with a shear plate 20, and the outer wall of the shear plate 20 is provided with a shear hole, so that the liquid repeatedly passes through the shear hole and collides with the shear plate 20, which can promote the emulsification of the liquid and make the adjuvant and the antigen fully mixed;
[0021] like Figure 3 As shown, the inner wall of the connecting pipe 12 is provided with two sealing rings 21 which are in contact with the outer walls of the first connecting pipe 9 and the second connecting pipe 11 respectively, thereby increasing the sealing performance of the connection between the first connecting pipe 9 and the second connecting pipe 11, which is more practical;
[0022] like Figure 1-2 As shown, two hydraulic cylinders 16 are arranged on the outer wall of the bracket 2, and the output shafts of the two hydraulic cylinders 16 are fixed with a push plate 17 which can push the first push rod 7 and the second push rod 15 to move. The first push rod 7 and the second push rod 15 can be pushed respectively by the two hydraulic cylinders 16. When the hydraulic cylinder 16 contracts and pushes the first push rod 7, the other hydraulic cylinder 16 extends to avoid blocking the movement of the second push rod 15, which is relatively perfect.
[0023] like Figure 1-2As shown, a scale line 19 is provided on one side of the first accommodating tube 3, which is relatively perfect, so that when adding raw materials into the first accommodating tube 3, the materials can be added accurately;
[0024] like Figure 1-2 As shown, the inner walls of the first accommodating cylinder 3 and the second accommodating cylinder 10 are both provided with limiting rings 18 that can limit the first piston 4 and the second piston 14, so as to limit the movement of the first piston 4 and the second piston 14, prevent the first piston 4 from escaping from the first accommodating cylinder 3, and prevent the second piston 14 from escaping from the second accommodating cylinder 10, which is more practical.
[0025] The working principle of the utility model is as follows: when in use, virus protein and adjuvant raw materials are added into the first accommodating tube 3 through the feeding hole 5, the sealing plug 6 is covered, and the two hydraulic cylinders 16 are started. Under the control of the external PLC system, the output shaft of one hydraulic cylinder 16 is retracted, and the other hydraulic cylinder 16 is pushed out, and the upper push plate 17 is cooperated to make the first piston 4 and the second piston 14 move back and forth in the first accommodating tube 3 and the second accommodating tube 10 respectively. The liquid repeatedly passes through the shear hole and collides with the shear plate 20 to promote emulsification and make the mixing more complete. After the mixing is completed, the mixed liquid is pushed into the first accommodating tube 3, and then the connecting pipe 12 is manually moved downward to separate the connecting pipe 12 from the first connecting pipe 9, and then the turntable 8 is rotated. The turntable 8 drives the first connecting pipe 9 to rotate to one side, and then the hydraulic cylinder 16 at the top is started to drive the first piston 4 to move downward, so that the mixed liquid in the first accommodating tube 3 is discharged from the first connecting pipe 9, thereby facilitating the material taking of the feeding box and improving the working efficiency.
[0026] The above is only a preferred embodiment of the present invention. It should be noted that, for ordinary technicians in the field, several improvements and modifications can be made without departing from the principle of the present invention, and these improvements and modifications should also be regarded as the protection scope of the present invention. The structures, devices and operating methods not specifically described and explained in the present invention shall be implemented according to the conventional means in the field unless otherwise specified and limited.
Claims
1. A device for mixing viral protein and adjuvant, characterized in that: The invention comprises a base (1), a bracket (2) is arranged on one side of the top of the base (1), a first accommodating cylinder (3) is arranged on one side of the bracket (2), a first piston (4) is slidably and sealingly mounted inside the first accommodating cylinder (3), a feeding hole (5) is opened on one side of the top of the first piston (4), a sealing plug (6) is arranged inside the feeding hole (5), a first push rod (7) is fixed on the top of the first piston (4) and on one side of the feeding hole (5), a rotating disk (8) is rotatably and sealingly mounted on the bottom of the first accommodating cylinder (3), a first connecting pipe (9) is passed through and fixed on one side of the bottom of the rotating disk (8), and a first connecting pipe (9) is fixed on one side of the bracket (2) and on the first connecting pipe (9). A second accommodating cylinder (10) is arranged below the through tube (9), a second communicating tube (11) is fixedly passed through one side of the top of the second accommodating cylinder (10), a connecting tube (12) is slidably mounted on the outer wall of the second communicating tube (11) corresponding to the first communicating tube (9), and the bottom of the first communicating tube (9) is inserted into the connecting tube (12) and is connected to the second communicating tube (11), a spring (13) is fixed at the bottom of the connecting tube (12), and the bottom end of the spring (13) is fixed to the top of the second communicating tube (11), a second piston (14) is sealingly slidably mounted inside the second accommodating cylinder (10), and a second push rod (15) is fixed at the bottom of the second piston (14).
2. A viral protein and adjuvant mixing and stirring device according to claim 1, characterized in that: The inner wall of the second connecting pipe (11) is provided with a shear plate (20), and the outer wall of the shear plate (20) is provided with a shear hole.
3. A viral protein and adjuvant mixing and stirring device according to claim 1, characterized in that: The inner wall of the connecting pipe (12) is provided with two sealing rings (21) which are in contact with the outer walls of the first connecting pipe (9) and the second connecting pipe (11) respectively.
4. A viral protein and adjuvant mixing and stirring device according to claim 1, characterized in that: Two hydraulic cylinders (16) are arranged on the outer wall of the bracket (2), and output shafts of the two hydraulic cylinders (16) are fixed with push plates (17) capable of pushing the first push rod (7) and the second push rod (15) to move.
5. A viral protein and adjuvant mixing and stirring device according to claim 1, characterized in that: A scale mark (19) is provided on one side of the first accommodating cylinder (3).
6. A viral protein and adjuvant mixing and stirring device according to claim 1, characterized in that: The inner walls of the first accommodating cylinder (3) and the second accommodating cylinder (10) are both provided with limiting rings (18) capable of limiting the positions of the first piston (4) and the second piston (14).