Three-axis movement device for full-automatic immunohistochemical staining machine

Abstract

The utility model discloses an X-axis movement mechanism, a Y-axis movement mechanism and a Z-axis movement mechanism. The X-axis movement mechanism comprises a Y-axis bottom plate and a Y-axis supporting piece fixed to the Y-axis bottom plate, and an X-axis and Y-axis connecting piece and an X-axis linear rail sliding block matched with the X-axis and Y-axis connecting piece are installed on the Y-axis bottom plate. The Z-axis movement mechanism comprises a YZ-axis motor and a straight gear which are fixed on the Y-axis bottom plate, the YZ-axis motor is connected with a ball spline shaft through a coupler, and the straight gear is connected with a cylindrical rack through a sliding sleeve assembly; the Y-axis movement mechanism comprises a Y-axis synchronous belt, a group of YZ-axis synchronous wheels and a group of YZ-axis follow-up wheel shafts, the YZ-axis synchronous wheels and the YZ-axis follow-up wheel shafts are fixed on a Y-axis bottom plate, the YZ-axis synchronous wheels are connected with the YZ-axis follow-up wheel shafts in a matched mode, and the Y-axis synchronous belt is connected with the YZ-axis follow-up wheel shafts and the YZ-axis synchronous wheels in a matched mode. The device can quickly move in the X, Y and Z directions, liquid is sucked out through the sample injection needle, and the liquid is injected after the device moves to a specified position, so that fixed-point injection of the sample injection needle is realized.

Description

Technical Field

[0001] The utility model belongs to the technical field of full-automatic immunohistochemical staining machines, and in particular relates to a three-axis motion device used for full-automatic immunohistochemical staining machines. Background Art

[0002] The fully automatic immunohistochemical staining machine can be used to quickly and accurately perform immunohistochemical staining and cell analysis on tissue sections.

[0003] Immunohistochemistry is a method that uses the specific binding of antibodies to corresponding antigens to detect specific molecules, and has been widely used in the field of medical diagnosis. However, traditional immunohistochemistry requires manual operation and chemical staining, which are not only time-consuming and labor-intensive, but also prone to errors. With the advancement of technology, automated immunohistochemistry has gradually emerged and developed. Although automated immunohistochemistry has made great progress, there are still some limitations, such as human errors that are prone to occur during operation, traditional sampling methods that are susceptible to contamination, and complex operating procedures, which affect the accuracy of the results. Therefore, it is necessary to develop a more advanced three-axis motion device for fully automatic immunohistochemistry staining machines to accurately complete the sampling and reagent addition steps to improve the accuracy and efficiency of immunohistochemistry. Summary of the invention

[0004] To solve the deficiencies of the prior art, the utility model aims to provide a three-axis motion device for a fully automatic immunohistochemical staining machine, which can be quickly maneuvered in the X, Y, and Z directions to achieve fixed-point injection of a sample injection needle.

[0005] In order to achieve the above objectives, the utility model adopts the following technical solutions:

[0006] A three-axis motion device for a fully automatic immunohistochemical staining machine comprises an X-axis motion mechanism, a Y-axis motion mechanism and a Z-axis motion mechanism; the X-axis motion mechanism comprises a Y-axis base plate and a Y-axis support member fixed on the Y-axis base plate, an XY-axis connecting member and an X-axis rail slider matched with the XY-axis connecting member are installed on the Y-axis base plate; the Z-axis motion mechanism comprises a YZ-axis motor and a spur gear fixed on the Y-axis base plate, the YZ-axis motor is connected to a ball spline shaft through a coupling, the spur gear is sleeved on the outside of the ball spline shaft and can slide along the central axis direction of the ball spline shaft, and the spur gear is connected to a cylindrical rack through a sliding sleeve assembly; the Y-axis motion mechanism comprises a Y-axis synchronous belt, a group of YZ-axis synchronous wheels fixed on the Y-axis base plate and a YZ follower wheel shaft, the YZ-axis synchronous wheel is matched and connected with the YZ-axis follower wheel shaft, the Y-axis synchronous belt is matched and connected with the YZ-axis follower wheel shaft and the YZ-axis synchronous wheel, the Y-axis synchronous belt is fixed through a belt pressing plate, and the belt pressing plate is connected to a sliding sleeve fixing seat through screws.

[0007] Preferably, the aforementioned sleeve assembly includes a sleeve fixing seat and a ball sleeve matched with the sleeve fixing seat through a bearing, the cylindrical rack is fixed in the sleeve fixing seat, and the ball sleeve is connected with the spur gear through the bearing.

[0008] Preferably, a Y-axis line rail and a Y-axis line rail slider matched with the Y-axis line rail are installed on the aforementioned Y-axis base plate.

[0009] Preferably, a camera fixing plate is installed on the aforementioned sliding sleeve fixing seat, a camera fixing frame is installed on the camera fixing plate, a PCB board fixing seat is installed on the camera fixing frame, and a code scanning camera is installed on the PCB board fixing seat.

[0010] Preferably, a limiting plate is provided on the top of the aforementioned sliding sleeve fixing seat, and the injection needle capillary is inserted inside.

[0011] Preferably, a terminal post is inserted into the aforementioned cylindrical rack, and one side of the terminal post is fixedly connected to a shading sheet.

[0012] Preferably, the aforementioned sliding sleeve fixing seat is fixedly connected to the U-shaped switch, the Y-direction shading sheet and the drag chain fixing frame, and the liquid level sensor is installed on the drag chain fixing frame.

[0013] The utility model is beneficial in that: the utility model has a simple structure and can be quickly maneuvered in the X, Y, and Z directions. The liquid is sucked out through the injection needle, moved to a designated position, and then the liquid is injected to achieve fixed-point injection of the injection needle, which simplifies the operation process and reduces the possibility of manual errors; the QR code on the reagent bottle can be scanned by the code scanning camera, thereby improving work efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 It is a front view of the utility model;

[0015] Figure 2 It is a right view of the utility model;

[0016] Figure 3 It is a schematic diagram of the internal structure of the utility model;

[0017] Figure 4 yes Figure 1 Middle AA section;

[0018] Figure 5 It is a rear view of the utility model;

[0019] Figure 6 yes Figure 5 Middle DD cross-section.

[0020] The meaning of the reference numerals in the figure: 1-X axis rail slider, 2-Y axis support, 3-rubber-coated bearing, 4-Y axis base plate, 5-Y axis rail, 6-Y axis rail slider, 7-injection needle, 8-cylindrical rack, 9-terminal, 10-hexagonal flat end set screw, 11-injection needle capillary, 12-sleeve, 13-ball sleeve, 14-bearing, 15-sleeve fixing seat, 16-flat washer, 17-hexagonal cylindrical head screw, 18-limiting plate, 19-hexagonal semicircular head screw, 20-limiting block, 21-U-type switch, 22-YZ axis motor, 23-YZ synchronous wheel, 24-YZ follower wheel shaft, 26-opening ring, 27-belt pressure plate, 28-ball spline shaft, 29-bearing seat, 30-rubber-coated screw, 31- Bearing, 32-coupling, 33-motor fixing seat, 34-shading sheet, 35-Y-axis synchronous belt, 36-mechanical limit seat, 37-Y-axis shading sheet, 38-liquid level sensor, 39-drag chain fixing bracket, 40-PMU through-plate two-way internal thread connector, 41-Y tank with drag chain, 42-Y tank with drag chain a, 43-Y-axis tank chain drag rack, 44-hexagonal nut, 45-camera fixing plate, 46-camera fixing bracket, 47-code scanning adapter plate, 48-code scanning camera, 49-cross slot pan head screw, 50-pcb board fixing seat, 51-code scanning cover, 52-cross slot pan head screw, 53-cross slot pan head screw, 54-transition plate, 55-Y-axis tensioner, 56-spur gear, 57-XY axis connecting parts. DETAILED DESCRIPTION

[0021] The present invention is described in detail below with reference to the accompanying drawings and specific embodiments.

[0022] See also Figures 1 to 6 The utility model discloses a three-axis motion device for a 96-chip machine, comprising an X-axis motion mechanism, a Y-axis motion mechanism and a Z-axis motion mechanism.

[0023] Screw the rubber-coated bearing 3 into the Y-axis support 2, tighten the Y-axis support 2 and the Y-axis base plate 4 with screws, tighten the X-axis line rail slider 1 and the XY-axis connecting piece 57 with screws, tighten the XY-axis connecting piece 57 and the Y-axis base plate 4 with screws, and the rolling of the rubber-coated bearing 3 can make the machine perform X-axis movement.

[0024] Tighten the Y tank belt drag chain 41, the Y tank belt drag chain a 42 and the Y axis bottom plate 4 with screws, insert the ball spline shaft 28 into the hole of the above combination, match the coupling 32 with the ball spline shaft 28, match the coupling 32 with the Y axis bottom plate 4, put the cylindrical rack 8 into the sliding sleeve fixing seat 15, insert the ball sliding sleeve 13 into the spur gear 56, match the bearing 31 with the spur gear 56, put it into the sliding sleeve fixing seat 15, match the bearing 14 with the sliding sleeve fixing seat 15, and then lock them with screws. The YZ axis motor 22 drives the coupling 32 and the ball spline shaft 28 to rotate, the ball spline shaft 28 drives the spur gear 56 to rotate, and the spur gear 56 drives the cylindrical rack 8 to move, so that the machine can move on the Z axis. The Y and Z axis motors 22 and the ball spline shaft 28 can be connected through the coupling 32 to rotate together, which plays a role in buffering and shock absorption.

[0025] Tighten the Y axis rail 5 and the Y axis base plate 4 with screws, match the Y axis rail slider 6 with the Y axis rail 5, then place the above assembly on it, and then tighten it with screws. Match the YZ axis motor 22 with the motor fixing seat 33, and tighten the other YZ axis motor 22 with the Y axis base plate 4 with screws. Tighten the YZ synchronous wheel 23, the YZ follower wheel shaft 24 and the Y axis base plate 4 with screws, match the YZ synchronous wheel 23 with the YZ follower wheel shaft 24, and then match the Y axis synchronous belt 35 with the YZ follower wheel shaft 24 and the YZ synchronous wheel 23, and press the Y axis synchronous belt 35 with the belt pressing plate 27, and tighten the belt pressing plate 27 with the sliding sleeve fixing seat 15 with screws. The Y axis synchronous belt 35 is driven by the YZ axis motor 22, and the Y axis synchronous belt 35 drives the sliding sleeve fixing seat 15 to move, so that the machine can move on the Y axis. The belt pressing plate 27 can make the synchronous belt 35 pressed tighter and not too loose.

[0026] Tighten one bearing seat 29 and the Y-axis base plate 4 with screws, put the bearing 31 into the hole of the bearing seat 29, tighten the rubber-coated screw 30 and the bearing seat 29, tighten the other bearing seat 29 and the Y-axis base plate 4 with screws, and put the bearing 31 into the hole of the bearing seat 29.

[0027] The code scanning camera 48 is fitted with the code scanning adapter plate 47, the code scanning camera 48 is screwed to the PCB board fixing seat 50, the code scanning cover 51 is screwed to the PCB board fixing seat 50, the camera fixing frame 46 is screwed to the PCB board fixing seat 50, and the camera fixing plate 45 is screwed to the camera fixing frame 46. The two-dimensional code on the reagent bottle can be scanned by the camera.

[0028] Tighten the camera fixing plate 45 and the sleeve fixing seat 15 with screws, tighten the Y-axis tank chain drag frame 43 and the sleeve fixing seat 15 with screws, put the sleeve 12 into the sleeve fixing seat 15, match the limit plate 18 with the sleeve fixing seat 15, and then lock it with screws, insert the injection needle capillary 11 into the limit block 20, and then put it into the sleeve fixing seat 15, insert the terminal 9 into the cylindrical rack 8, and then lock it with screws. Tighten the shading sheet 34 and the terminal 9 with screws, tighten the U-shaped switch 21, the Y-axis shading sheet 37, the drag chain fixing frame 39 and the sleeve fixing seat 15 with screws, tighten the liquid level sensor 38 and the drag chain fixing frame 39 with screws, and lock the drag chain fixing frame 39 with the PMU-through-plate two-way internal threaded connector 40 and the hexagonal nut 44.

[0029] Tighten the U-shaped switch 21, 36 mechanical limit seats, the Y-axis tensioner 55 and the Y-axis bottom plate 4 with screws, tighten the U-shaped switch 21 and the mechanical limit seat 36 with screws, and screw the rubber-coated screw 30 into the mechanical limit seat 36. Fit the transition plate 54 and the Y-axis bottom plate 4 together.

[0030] The above shows and describes the basic principle, main features and advantages of the utility model. Those skilled in the art should understand that the above embodiments do not limit the utility model in any form, and any technical solution obtained by equivalent replacement or equivalent transformation falls within the protection scope of the utility model.

Claims

1. A three-axis motion device for a fully automatic immunohistochemical staining machine, characterized in that: X-axis motion mechanism, Y-axis motion mechanism and Z-axis motion mechanism; The X-axis motion mechanism comprises a Y-axis base plate (4) and a Y-axis support member (2) fixed on the Y-axis base plate (4); an XY-axis connecting member and an X-axis axis rail slider matched with the XY-axis connecting member are mounted on the Y-axis base plate (4); The Z-axis motion mechanism comprises a YZ-axis motor (22) and a spur gear (56) fixed on a Y-axis base plate (4); the YZ-axis motor (22) is connected to a ball spline shaft (28) via a coupling (32); the spur gear (56) is sleeved on the outside of the ball spline shaft (28) and can slide along the central axis direction of the ball spline shaft (28); and the spur gear (56) is connected to a cylindrical rack (8) via a sliding sleeve assembly; The Y-axis motion mechanism comprises a Y-axis synchronous belt (35), a group of YZ synchronous wheels (23) and a YZ follower wheel shaft (24) fixed on the Y-axis bottom plate (4), the YZ synchronous wheel (23) is cooperatively connected to the YZ follower wheel shaft (24), the Y-axis synchronous belt (35) is cooperatively connected to both the YZ follower wheel shaft (24) and the YZ synchronous wheel (23), the Y-axis synchronous belt (35) is fixed by a belt pressing plate (27), and the belt pressing plate (27) is connected to the sliding sleeve fixing seat (15) by screws.

2. A three-axis motion device for a fully automatic immunohistochemical staining machine according to claim 1, characterized in that: The sleeve assembly comprises a sleeve fixing seat (15) and a ball sleeve (13) matched with the sleeve fixing seat via a bearing, the cylindrical rack (8) is fixed in the sleeve fixing seat (15), and the ball sleeve (13) is matched with the spur gear (56) via a bearing.

3. A three-axis motion device for a fully automatic immunohistochemical staining machine according to claim 1, characterized in that: A Y-axis rail (5) and a Y-axis rail slider (6) matched with the Y-axis rail (5) are installed on the Y-axis base plate (4).

4. A three-axis motion device for a fully automatic immunohistochemical staining machine according to claim 1, characterized in that: A camera fixing plate (45) is mounted on the sliding sleeve fixing seat (15), a camera fixing frame (46) is mounted on the camera fixing plate (45), a PCB board fixing seat (50) is mounted on the camera fixing frame (46), and a code scanning camera (48) is mounted on the PCB board fixing seat (50).

5. A three-axis motion device for a fully automatic immunohistochemical staining machine according to claim 2, characterized in that: A limiting plate (18) is provided on the top of the sliding sleeve fixing seat (15), and an injection needle capillary (11) is inserted into the interior.

6. A three-axis motion device for a fully automatic immunohistochemical staining machine according to claim 1, characterized in that: A terminal post (9) is inserted into the cylindrical rack (8), and one side of the terminal post (9) is fixedly connected to a light shielding sheet (34).

7. A three-axis motion device for a fully automatic immunohistochemical staining machine according to claim 1, characterized in that: The sliding sleeve fixing seat (15) is fixedly connected to the U-shaped switch (21), the Y-direction light shielding sheet (37) and the drag chain fixing frame (39), and the liquid level sensor (38) is installed on the drag chain fixing frame (39).

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