Liquid chromatography column packing machine

By using a cable pulling mechanism driven by a two-way motor in the liquid chromatographic column loader, the problem of easy twisting and drop of the chromatographic column in the existing technology is solved, and a more efficient and safe filling process is achieved, and the chromatographic filling process is improved. Stability and service life of the column.

CN222144949UActive Publication Date: 2024-12-10SHANDONG YING KAI LONG TECH DEV CO LTD
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Patent Information

Application Number
CN202323623572.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2023-12-29
Publication Date
2024-12-10
Estimated Expiration
2033-12-29

AI Technical Summary

Technical Problem

The existing liquid chromatographic column loading machine clamping devices rely on elastic fixing frames, which easily cause the column to twist and fall during the filling process, affecting the filling efficiency and safety.

Method used

The liquid chromatographic column loader design includes a base, drive assembly and clamping assembly. The transmission shaft and reel are driven by a bidirectional motor, and the cable pulling mechanism is used to achieve stable clamping of the chromatographic column, improving stability and contact force.

Benefits of technology

It significantly improves the stability and filling efficiency of the chromatographic column, reduces friction and deformation of the clamping device, extends service life, and enhances the safety of the filling process.

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Abstract

The utility model discloses a liquid chromatography column packing machine which comprises a base, a driving assembly, a shell, a bidirectional motor, a transmission shaft, a first bevel gear, a second bevel gear, a winding shaft, a buckling device, a cable, a supporting shell, a clamping assembly, a fixing plate and first clamping plates. The inner wall of the second clamping plate is fixedly connected with one end of a cable; according to the scheme, compared with a traditional mode that the clamping plates are fixed through springs and elastic pieces, the cable is higher in stability compared with the springs and the elastic pieces, the fixed plate, the first clamping plate and the second clamping plate cannot deform too much in the shaking process of the chromatographic column, and due to the fact that the fixed plate, the first clamping plate and the second clamping plate are pulled through the cable, in the filling process of the chromatographic column, the clamping plates are not prone to deformation. The contact stability with the fixed plate, the first clamping plate and the second clamping plate is higher, so that the chromatographic column is not easy to shake, and the working efficiency in the chromatographic column filling process can be greatly improved as the stability of the chromatographic column is improved.
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Description

Technical Field

[0001] The present application relates to the technical field of liquid chromatography column clamping, and in particular to a liquid chromatography column packing machine. Background Art

[0002] Liquid chromatography separation technology is currently the most commonly used separation and purification technology. According to the working pressure, liquid chromatography technology can be divided into low-pressure, medium-pressure, high-pressure and ultra-high-pressure chromatography. Among them, medium-low pressure chromatography (pressure is 1-20kgf) is widely used because it is easy to implement, simple and cheap. The filling technology of the chromatographic column is an important factor affecting the performance of chromatographic analysis. For medium-low pressure chromatography, since the filler particles are large, generally greater than 30μm, dry filling is often used.

[0003] The chromatographic column packing machine needs to use a clamping device to clamp the outer wall of the chromatographic column to ensure the stability of the chromatographic column and facilitate the filling of the chromatographic column. The existing chromatographic column outer wall clamping device generally only relies on an elastic fixing frame to clamp the chromatographic column tube. The elastic fixing frame is generally two sets of clamping plates, and elastic components such as springs and shrapnel are arranged inside. The chromatographic column tube will be subjected to a certain torque during the filling process. Once the torsion amplitude of the chromatographic column tube is too large, it is very easy to separate the two clamps of the elastic fixing frame, causing the chromatographic column tube to fall, which is not convenient for the filling operation. Therefore, those skilled in the art provide a liquid chromatography column packing machine to solve the problems raised in the above background technology. Utility Model Content

[0004] In order to solve the problems raised in the above background technology, the present application provides a liquid chromatography column packing machine.

[0005] A liquid chromatography column packing machine provided in this application adopts the following technical solution:

[0006] A liquid chromatography column packing machine comprises a base, one side of the base is fixedly connected with a column packing machine socket and a support frame, the column packing machine socket is located on one side of the support frame, and a slider is slidably provided inside the support frame;

[0007] A driving assembly is arranged on one side of the slider, the driving assembly comprises a shell fixedly connected to one side of the slider, a bidirectional motor is fixedly connected to one side of the inner wall of the shell, both output ends of the bidirectional motor are fixedly connected to a transmission shaft through a coupling, one end of the two groups of transmission shafts are fixedly connected to a first bevel gear, one side of the two groups of the first bevel gears are meshedly connected to a second bevel gear, a winding shaft is fixedly plugged at the axis of the second bevel gear, the winding shaft is located inside the shell and rotates, a buckle device is symmetrically arranged on one side of the winding shaft, and a cable is arranged inside the buckle device;

[0008] A supporting shell is arranged on one side of the outer shell, and a clamping assembly is arranged on the side of the supporting shell away from the outer shell, and the clamping assembly includes fixing plates respectively fixedly connected to one side of two groups of the supporting shells, one side of the two groups of the fixing plates is connected with a first clamping plate, one side of the two groups of the first clamping plates is connected with a second clamping plate, and the inner wall of the second clamping plate is fixedly connected to one end of the cable.

[0009] In some embodiments, a threaded shaft is inserted into the internal thread of the slider, and one end of the threaded shaft passes through the support frame.

[0010] In some embodiments, slide rails are fixedly connected to both sides of the inner wall of the support frame, and the sides of the two slide rails close to each other are in contact with the outer walls of both sides of the sliding block.

[0011] In some embodiments, guide components are symmetrically arranged inside the fixing plate and the first clamping plate, and the guide components are symmetrically sleeved on the surface of the cable respectively.

[0012] In some embodiments, the guide assembly includes a support seat fixedly connected to the fixed plate and the inner wall of the first clamping plate respectively, a bearing disk is symmetrically arranged on one side of the support seat, a limiting column is symmetrically arranged on one side of the bearing disk, and the limiting columns are symmetrically sleeved on the surface of the cable.

[0013] In some embodiments, multiple snap-on devices include threaded rings that are threadedly plugged into the winding shaft and the surface of the second clamping plate, respectively; one side of each of the threaded rings is fixedly connected to a sleeve; one side of the sleeve is threadedly plugged with a top cover; multiple top covers are sleeved on both ends of the two groups of cables; both ends of the two groups of cables are fixedly connected to a fixing plate; and multiple fixing plates are respectively located inside the multiple top covers.

[0014] In summary, this application includes the following beneficial technical effects:

[0015] (1) The staff only needs to insert the chromatographic column into the socket of the column loading machine, and place the chromatographic column vertically on one side of the driving assembly. The staff controls the rotation of the bidirectional motor through the button. The bidirectional motor drives the transmission shaft, the first bevel gear, the second bevel gear and the winding shaft to rotate during the forward rotation. The two winding shafts pull the cables on the side close to each other on the surface. The two cables pull the second clamping plates at one end respectively. The second clamping plate is hinged to the first clamping plate on one side, and the first clamping plate is hinged to the fixed plate on one side, so that the first clamping plate on one side of the fixed plate rotates, and the second clamping plate on one side of the first clamping plate rotates. The second clamping plates are pulled closer to each other by the pulling of the cables, and the sides of the two second clamping plates close to each other are pulled against the surface of the chromatographic column. The surface is wrapped so that the outer surface of the chromatographic column is tightly attached to the supporting shells, the fixed plate, the first clamp and the second clamp on both sides. The fixed plate, the first clamp and the second clamp are wrapped by the fixed plate, the first clamp and the second clamp. Compared with the traditional spring and spring sheet fixing the clamp, the cable has higher stability than the spring and the spring sheet. During the shaking of the chromatographic column, the fixed plate, the first clamp and the second clamp will not be deformed too much. Due to the pulling of the cable, the fixed plate, the first clamp and the second clamp have higher contact stability with the fixed plate, the first clamp and the second clamp during the filling process, so that the chromatographic column is not easy to shake. Due to the improved stability of the chromatographic column, the work efficiency during the filling process of the chromatographic column can be greatly increased.

[0016] (2) Each group of two guide components is respectively arranged on the fixed plate and the first clamping plate. The two guide components respectively guide the cables passing through the fixed plate and the first clamping plate, so that the cables can reduce the friction with the inner wall of the fixed plate and the first clamping plate during operation, thereby increasing the service life. The guide components are composed of a support seat, a bearing disk and a limit column. The bearing disk is located at the connection between the support seat and the limit column. The staff fixes the support seat on the inner wall of the fixed plate and the first clamping plate. The support seat supports the bearing disk and the limit column. The limit column rotates on one side of the support seat through the bearing disk. A groove is provided on one side of the limit column. The cable is placed inside the limit column through the groove. The limit column limits the cable, thereby reducing the friction between the cable and the inner wall of the fixed plate and the first clamping plate, thereby increasing the service life of the cable. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a structural schematic diagram of the overall structure in the embodiment of the present application;

[0018] Figure 2 is a schematic diagram of a side cross-section structure of an embodiment of the present application;

[0019] Figure 3 It is a schematic diagram of the structure of the reel in the embodiment of the present application;

[0020] Figure 4 is a schematic diagram of the structure of the buckle device in the embodiment of the present application;

[0021] Figure 5 is a schematic diagram of the structure of the guide assembly in the embodiment of the present application;

[0022] Figure 6 In the embodiment of this application Figure 1 Schematic diagram of the structure at A.

[0023] Explanation of the accompanying drawings: 1. base; 2. column mounting machine socket; 3. support frame; 31. threaded shaft; 32. slide rail; 4. slider; 5. drive assembly; 51. housing; 52. bidirectional motor; 521. transmission shaft; 53. first bevel gear; 54. second bevel gear; 55. winding shaft; 56. snap device; 561. sleeve; 562. threaded ring; 563. top cover; 564. fixed disk; 57. cable; 6. support shell; 7. clamping assembly; 71. fixed plate; 72. first clamping plate; 73. second clamping plate; 8. guide assembly; 81. support seat; 82. bearing disk; 83. limit column. DETAILED DESCRIPTION

[0024] The following is combined with Figure 1-6 This application is described in further detail.

[0025] The present application embodiment discloses a liquid chromatography column packing machine. Figure 1-6 A liquid chromatography column packing machine comprises a base 1, a driving assembly 5 and a supporting shell 6, one side of the base 1 is fixedly connected with a column packing machine socket 2 and a supporting frame 3, the column packing machine socket 2 is located on one side of the supporting frame 3, a slider 4 is slidably arranged inside the supporting frame 3, the driving assembly 5 is arranged on one side of the slider 4, the driving assembly 5 comprises a shell 51 fixedly connected to one side of the slider 4, one side of the inner wall of the shell 51 is fixedly connected with a bidirectional motor 52, both sides of the output ends of the bidirectional motor 52 are fixedly connected with a transmission shaft 521 through a coupling, one end of two sets of transmission shafts 521 are fixedly connected with a first bevel gear 53, and one side of the two sets of first bevel gears 53 are meshed and connected A second bevel gear 54, a winding shaft 55 is fixedly inserted at the axis center of the second bevel gear 54, the winding shaft 55 is located inside the shell 51 and rotates, a snap device 56 is symmetrically provided on one side of the winding shaft 55, a cable 57 is provided inside the snap device 56, a support shell 6 is provided on one side of the shell 51, a clamping assembly 7 is provided on the side of the support shell 6 away from the shell 51, the clamping assembly 7 includes a fixing plate 71 fixedly connected to one side of the two groups of support shells 6 respectively, a first clamping plate 72 is intersected on one side of the two groups of fixing plates 71, a second clamping plate 73 is intersected on one side of the two groups of first clamping plates 72, and an inner wall of the second clamping plate 73 is fixedly connected to one end of the cable 57.

[0026] In this way, during the implementation process, when it is necessary to clamp the chromatographic column, the staff will place the column loading machine socket 2 above the base 1, and place the support frame 3 on one side of the column loading machine socket 2, and support the slider 4 through the support frame 3, and the slider 4 supports the driving component 5, the support shell 6 and the clamping component 7. Then the staff will insert the inlet end of the chromatographic column into the column loading machine socket 2, and the chromatographic column is perpendicular to one side of the support frame 3. The chromatographic column is located inside the symmetrical clamping component 7. A button is provided on one side of the outer wall of the shell 51, and the button controls the forward and reverse rotation of the bidirectional motor 52. Pressing the button rotates the bidirectional motor 52, and the bidirectional motor 52 rotates. The rotation of 52 drives the transmission shafts 521 at the output ends on both sides to rotate. The two transmission shafts 521 drive the winding shaft 55 to rotate through the two mutually meshing first bevel gears 53 and second bevel gears 54 at the ports. The two ends of the winding shaft 55 are inserted into the inner wall of the shell 51. The two winding shafts 55 rotate in opposite directions. During the rotation of the two winding shafts 55, the two buckle devices 56 on the surface are respectively driven to rotate. During the rotation of the winding shaft 55, the cable 57 is wound. The surface of the winding shaft 55 is symmetrically provided with winding grooves. The cable 57 will automatically be stuck in the inside of the winding groove during the process of winding around the winding shaft 55, so that the cable 57 itself is not easy to be entangled;

[0027] Then, the support shell 6 and the clamping assembly 7 are fixed to one side of the shell 51 respectively, and the two fixed support shells 6 and the two clamping assemblies 7 are symmetrically placed. The two clamping assemblies 7 have the same structure. The clamping assembly 7 is composed of a fixed plate 71, a first clamping plate 72 and a second clamping plate 73. One side of the first clamping plate 72 is inserted into the interior of the fixed plate 71, and the fixed plate 71 is hinged to the first clamping plate 72 through the fixing bolts inserted on both sides, so that the first clamping plate 72 is located inside the fixed plate 71 and rotates. There is a certain gap between the outer wall of the first clamping plate 72 and the inner wall of the fixed plate 71, which is convenient for the rotation of the first clamping plate 72. One side of the second clamping plate 73 is inserted into the interior of the first clamping plate 72, and the first clamping plate 72 is hinged to the second clamping plate 73 through the fixing bolts inserted on both sides, so that the second clamping plate 73 is located inside the first clamping plate 72 and rotates. There is a certain gap between the outer wall of the second clamping plate 73 and the inner wall of the first clamping plate 72, which is convenient for the rotation of the second clamping plate 73. The two second clamping plates 73 are fixedly connected with anti-skid patterns on one side close to each other, and the anti-skid patterns can increase the surface friction of the two second clamping plates 73. The second clamping plate 73 fits the outer wall of the chromatographic column so that the chromatographic column is located between the two support shells 6 and the two clamping assemblies 7;

[0028] Then, both ends of the cables 57 are connected with snap devices 56. The snap device 56 at one end of each cable 57 is inserted into the inside of the second clamping plate 73, and the snap device 56 at the other end is inserted into the inside of the reel 55. Each set of reel 55 is equipped with two cables 57. The directions in which the two cables 57 are wound around the reel 55 are inconsistent. During the forward rotation of the reel 55, one cable 57 is wound and the other cable 57 is loosened. During the process of winding around the reel 55, one end of the wound cable 57 will pull the second clamping plate 73 at the other end, so that the two second clamping plates 73 are close to each other. During the reverse rotation of the reel 55, the other cable 57 is wound, so that the two second clamping plates 73 are away from each other.

[0029] In this way, during use, the staff only needs to insert the chromatographic column into the column loading machine socket 2 and place the chromatographic column vertically on one side of the driving assembly 5. The staff controls the rotation of the bidirectional motor 52 through the button. The bidirectional motor 52 drives the transmission shaft 521, the first bevel gear 53, the second bevel gear 54 and the winding shaft 55 to rotate during the forward rotation. The two winding shafts 55 pull the cables 57 on the side whose surfaces are close to each other. The two cables 57 pull the second clamping plate 73 at one end respectively. One side of the second clamping plate 73 is hinged to the first clamping plate 72, and one side of the first clamping plate 72 is hinged to the fixed plate 71, so that the first clamping plate 72 is located on the side of the fixed plate 71 and the second clamping plate 73 is located on the side of the first clamping plate 72 and rotates. The second clamping plates 73 are pulled closer to each other by the cable 57, and the side of the two second clamping plates 73 that are close to each other wraps the surface of the chromatographic column, so that the outer surface of the chromatographic column is tightly attached to the supporting shells 6, the fixed plate 71, the first clamping plate 72 and the second clamping plate 73 on both sides. Compared with the traditional fixation of the clamping plates by springs and spring sheets, the fixed plate 71, the first clamping plate 72 and the second clamping plate 73 have a higher contact stability with the fixed plate 71, the first clamping plate 72 and the second clamping plate 73 during the filling process due to the pulling of the cable 57, so that the chromatographic column is not easy to shake. Since the stability of the chromatographic column is improved, the work efficiency during the filling process of the chromatographic column can be greatly increased.

[0030] Among them, the internal thread of the slider 4 is plugged with a threaded shaft 31, one end of the threaded shaft 31 passes through the support frame 3, and one end of the threaded shaft 31 is inserted into the interior of the support frame 3. A bearing is provided at the connection between the support frame 3 and the threaded shaft 31 to reduce the friction between the threaded shaft 31 and the support frame 3. The other end of the threaded shaft 31 passes through the support frame 3 and is fixed with a turntable. The staff rotates the turntable by hand, and the turntable drives the threaded shaft 31 to rotate. The rotation of the threaded shaft 31 adjusts the height of the slider 4 engaged with the surface. The slider 4 adjusts the height of the drive assembly 5, the support shell 6 and the clamping assembly 7, and can pinch different positions of the chromatographic column to improve the stability of the chromatographic column during the filling process.

[0031] Preferably, slide rails 32 are fixedly connected to both sides of the inner wall of the support frame 3, and the sides of the two slide rails 32 that are close to each other are in contact with the outer walls of the slider 4 on both sides. The slide rails 32 are located on both sides of the inner wall of the support frame 3 for fixation, and slide grooves are provided on both sides of the slider 4. The slide rails 32 are close to each other and embedded in the slide grooves from one side, and both sides of the slider 4 are in contact with the slide rails 32. The slider 4 is limited by the slide rails 32, thereby increasing the stability of the slider 4 during the lifting process.

[0032] Specifically, the interior of the fixing plate 71 and the first clamping plate 72 are symmetrically provided with guide assemblies 8, and the symmetrical guide assemblies 8 are respectively sleeved on the surface of the cable 57. The guide assembly 8 includes a support seat 81 fixedly connected to the inner wall of the fixing plate 71 and the first clamping plate 72, and a bearing plate 82 is provided on one side of the symmetrical support seat 81. A limiting column 83 is provided on one side of the symmetrical bearing plate 82, and the symmetrical limiting columns 83 are sleeved on the surface of the cable 57.

[0033] The guide assemblies 8 are each arranged in two groups on the fixing plate 71 and the first clamping plate 72 respectively. The two guide assemblies 8 guide the cables 57 passing through the fixing plate 71 and the first clamping plate 72 respectively, so that the cables 57 can reduce the friction with the inner walls of the fixing plate 71 and the first clamping plate 72 during operation, thereby increasing the service life. The guide assembly 8 is composed of a support seat 81, a bearing disk 82 and a limiting column 83. The bearing disk 82 is located at the connection between the support seat 81 and the limiting column 83. The staff fixes the support seat 81 on the inner wall of the fixing plate 71 and the first clamping plate 72, and the support seat 81 supports the bearing disk 82 and the limiting column 83. The limiting column 83 rotates on one side of the support seat 81 through the bearing disk 82. A groove is provided on one side of the limiting column 83. The cable 57 is placed inside the limiting column 83 through the groove. The limiting column 83 limits the cable 57, thereby reducing the friction between the cable 57 and the inner walls of the fixing plate 71 and the first clamping plate 72, thereby increasing the service life of the cable 57.

[0034] More specifically, the plurality of buckle devices 56 include threaded rings 562 respectively threadedly plugged into the surfaces of the winding shaft 55 and the second clamping plate 73, one side of the plurality of threaded rings 562 is fixedly connected with a sleeve 561, one side of the sleeve 561 is threadedly plugged with a top cover 563, the plurality of top covers 563 are sleeved on both ends of the two sets of cables 57, both ends of the two sets of cables 57 are fixedly connected with a fixing plate 564, and the plurality of fixing plates 564 are respectively located inside the plurality of top covers 563;

[0035] Multiple snap-fit ​​devices 56 are respectively composed of a sleeve 561, a threaded ring 562, a top cover 563 and a fixed disk 564. The sleeve 561 and the threaded ring 562 are integrally connected. Multiple sleeves 561 are respectively fixed to the surfaces of the winding shaft 55 and the second clamping plate 73 through the threaded ring 562. The sleeve 561 limits the cable 57 through the top cover 563. One end of the cable 57 located inside the sleeve 561 is fixedly connected with a fixed disk 564. The diameter of the fixed disk 564 is larger than that of the end of the top cover 563 that is sleeved on the surface of the cable 57. The fixed disk 564 fixes the cable 57 to the inside of the top cover 563. The sleeve 561 and the top cover 563 are rotated to open, so that the fixed disk 564 and the cable 57 can be removed. After the cable 57 is detached from the fixed disk 564, the cable 57 can be replaced.

[0036] The implementation principle of a liquid chromatography column packing machine in the embodiment of the present application is as follows: when in use, the chromatographic column is inserted into the interior of the column packing machine socket 2, and the chromatographic column is placed vertically on one side of the driving component 5. The staff controls the rotation of the bidirectional motor 52 through the button. The bidirectional motor 52 drives the transmission shaft 521, the first bevel gear 53, the second bevel gear 54 and the winding shaft 55 to rotate during the forward rotation. The two winding shafts 55 pull the cables 57 on the side whose surfaces are close to each other. The two cables 57 pull the second clamping plate 73 at one end respectively. One side of the second clamping plate 73 is hinged to the first clamping plate 72, and one side of the first clamping plate 72 is hinged to the fixed plate 71, so that the first clamping plate 72 is located on one side of the fixed plate 71 and rotates. The second clamping plate 73 is located on the first clamping plate 72. One side rotates, and the second clamping plate 73 is pulled closer to each other by the cable 57. The side of the two second clamping plates 73 that are close to each other wraps the surface of the chromatographic column, so that the outer surface of the chromatographic column is tightly attached to the supporting shells 6, the fixed plate 71, the first clamping plate 72 and the second clamping plate 73 on both sides. Through the wrapping of the fixed plate 71, the first clamping plate 72 and the second clamping plate 73, compared with the traditional fixation of the clamping plate with a spring and a spring sheet, the fixed plate 71, the first clamping plate 72 and the second clamping plate 73 are pulled by the cable 57, so that the contact stability of the chromatographic column with the fixed plate 71, the first clamping plate 72 and the second clamping plate 73 during the filling process is higher, so that the chromatographic column is not easy to shake. Since the stability of the chromatographic column is improved, the work efficiency during the filling process of the chromatographic column can be greatly increased.

[0037] In the description of the present application, it should be noted that the terms "upper", "lower", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present application. Unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be a connection between the two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present application can be understood according to the specific circumstances.

[0038] It should be noted that, in this application, relational terms such as "first" and "second" are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the sentence "comprise a ..." do not exclude the presence of other identical elements in the process, method, article or device including the elements.

[0039] The above description is only a specific implementation of the present application, so that those skilled in the art can understand or implement the present application. Various modifications to these embodiments will be apparent to those skilled in the art, and the general principles defined herein can be implemented in other embodiments without departing from the spirit or scope of the present application. Therefore, the present application will not be limited to the embodiments shown herein, but will conform to the widest range consistent with the principles and novel features applied for herein.

Claims

1. A liquid chromatography column packing machine, characterized in that: include: A base (1), one side of the base (1) being fixedly connected with a column loading machine socket (2) and a support frame (3), the column loading machine socket (2) being located on one side of the support frame (3), and a slider (4) being slidably provided inside the support frame (3); A driving assembly (5) is arranged on one side of the slider (4), the driving assembly (5) comprising a housing (51) fixedly connected to one side of the slider (4), a bidirectional motor (52) fixedly connected to one side of the inner wall of the housing (51), both output ends of the bidirectional motor (52) fixedly connected to a transmission shaft (521) via a coupling, one end of two groups of the transmission shafts (521) fixedly connected to a first bevel gear (53), one side of the two groups of the first bevel gears (53) meshingly connected to a second bevel gear (54), a winding shaft (55) fixedly plugged at the axis of the second bevel gear (54), the winding shaft (55) being located inside the housing (51) and rotating, a buckle device (56) symmetrically arranged on one side of the winding shaft (55), a cable (57) arranged inside the buckle device (56); A support shell (6) is arranged on one side of the outer shell (51); a clamping assembly (7) is arranged on the side of the support shell (6) away from the outer shell (51); the clamping assembly (7) comprises fixing plates (71) respectively fixedly connected to one side of two groups of the support shells (6); a first clamping plate (72) is connected to one side of the two groups of the fixing plates (71); a second clamping plate (73) is connected to one side of the two groups of the first clamping plates (72); an inner wall of the second clamping plate (73) is fixedly connected to one end of the cable (57).

2. A liquid chromatography column packing machine according to claim 1, characterized in that: The internal thread of the slider (4) is plugged with a threaded shaft (31), and one end of the threaded shaft (31) passes through the support frame (3).

3. A liquid chromatography column packing machine according to claim 2, characterized in that: Slide rails (32) are fixedly connected to both sides of the inner wall of the support frame (3), and the sides of the two slide rails (32) that are close to each other fit with the outer walls of both sides of the sliding block (4).

4. A liquid chromatography column packing machine according to claim 1, characterized in that: The fixing plate (71) and the first clamping plate (72) are both symmetrically provided with guide components (8), and the guide components (8) are symmetrically sleeved on the surface of the cable (57) respectively.

5. A liquid chromatography column packing machine according to claim 4, characterized in that: The guide assembly (8) comprises a support seat (81) fixedly connected to the inner wall of the fixing plate (71) and the first clamping plate (72) respectively, a bearing plate (82) is symmetrically arranged on one side of the support seat (81), and a limiting column (83) is symmetrically arranged on one side of the bearing plate (82), and the limiting columns (83) are symmetrically sleeved on the surface of the cable (57).

6. A liquid chromatography column packing machine according to claim 1, characterized in that: The plurality of snap-fit ​​devices (56) include threaded rings (562) respectively threadedly plugged into the surfaces of the winding shaft (55) and the second clamping plate (73); one side of the plurality of threaded rings (562) is fixedly connected with a sleeve (561); one side of the sleeve (561) is threadedly plugged with a top cover (563); the plurality of top covers (563) are sleeved on both ends of the two groups of cables (57); both ends of the two groups of cables (57) are fixedly connected with a fixing plate (564); the plurality of fixing plates (564) are respectively located inside the plurality of top covers (563).

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