Flow antibody storage box

By designing array space units and limit structures of multi-side walls and partitions in the flow antibody storage box, combining porous sponge buffer pads and refrigeration media, the problem of misplaced positioning caused by inconsistent shape and labeling of the antibody bottle in the experiment was solved. , improves the experimental efficiency and the preservation effect of antibodies.

CN222158189UActive Publication Date: 2024-12-13ZHEJIANG INNOFORCE PHARMACEUTICALS CO LTD
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Patent Information

Application Number
CN202420631849.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-03-29
Publication Date
2024-12-13
Estimated Expiration
2034-03-29

AI Technical Summary

Technical Problem

The shape and label of flow antibody bottles of different manufacturers in the laboratory are inconsistent, which makes it difficult for experimental personnel to quickly find the antibodies they need, and it is prone to mis-take and placement problems. The existing solutions are costly and impractical.

Method used

A flow antibody storage box is designed, including a box body, a box lid and a buffer pad. A multiple side wall and partition are provided on the box body to form an array space unit, which is used to set fluorescent labels and name labels, combined with limit structures and porous sponge buffer pads, adapt to reagent bottles of different sizes, and set a refrigeration medium in the lid to prevent the antibody from deteriorating.

Benefits of technology

Accurate classification and rapid positioning of antibodies is achieved, errors are reduced, and it adapts to different brands and sizes of antibody bottles, reduces production costs, and extends the service life of antibodies through refrigeration media.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a flow type antibody storage box, which comprises a box body, a box cover and a cushion pad used for wrapping reagent bottles, the box body comprises a bottom plate, a plurality of side walls and a containing cavity formed by the bottom plate and the plurality of side walls, the plurality of side walls at least comprise a first side wall used for arranging a first label sequence, and a second side wall used for arranging a second label sequence. The first side wall is used for arranging a first label sequence, the second side wall is adjacent to the first side wall and used for arranging a second label sequence, and the containing cavity is internally provided with a plurality of first partition plates and a plurality of second partition plates which are parallel to the first side wall and the second side wall respectively; and the plurality of first partition plates and the plurality of second partition plates are connected in a staggered manner to form a plurality of array space units with the same or different shapes corresponding to the first label sequence and the second label sequence. The fluorescent marking area and the name marking area are arranged on the side wall of the box body, experimenters can conveniently and rapidly store and take corresponding antibody reagent bottles, different reagent grooves are designed according to the reagent bottles of different sizes, and the situation that in the storing and taking process of the whole storage box, the internal reagent bottles move, and internal partition layout is disturbed is prevented.
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Description

Technical Field

[0001] The utility model relates to the technical field of storage boxes, in particular to a flow antibody storage box. Background Art

[0002] Flow antibodies vary depending on the antibody type and fluorescent dye. In general, laboratories will have dozens to hundreds of different flow antibodies per bottle. The bottles of flow antibodies produced by different manufacturers are not the same. Therefore, it takes a long time for experimenters to find the required antibodies when doing experiments, which delays the progress of the experiment and is easy to get the wrong antibodies. For example, the Chinese utility model (publication number CN210775511U, publication date: June 16, 2020) "An enzyme-linked immunosorbent assay kit" discloses that the reagent is limited by a bottle limiter in the kit, and the bottle limiter is made of plastic foam, and the shape and size are not adjustable during use, which has limitations when used for different reagent bottles; in addition, the kit uses different colored bottle caps on the reagent bottles to distinguish them, and the bottles are affixed with obvious labels for identification. Although the use of different colored bottle caps and the use of labels on each reagent bottle improves the resolution of the reagent bottle to a certain extent, it is not economical and practical. When there are dozens or hundreds of types of reagent bottles, dozens or hundreds of bottle caps of different colors must be produced at the same time, causing certain cost problems and color classification problems. Summary of the invention

[0003] Purpose of the invention: The purpose of the utility model is to provide a flow antibody storage box that can accommodate different antibody reagent bottles and prevent the problem of reagent bottles being taken or placed incorrectly.

[0004] Technical solution: In order to achieve the above-mentioned purpose of the invention, the utility model provides a flow antibody storage box, including a box body, a box cover and a buffer pad for wrapping a reagent bottle, the box body including a bottom plate and a plurality of side walls, the plurality of side walls including at least a first side wall for setting a first label sequence, and a second side wall adjacent to the first side wall and for setting a second label sequence, the interior of the accommodating chamber is provided with a plurality of first partitions and a plurality of second partitions which are parallel to the first side wall and the second side wall respectively, the plurality of first partitions and the plurality of second partitions are staggeredly connected to form a plurality of array space units of the same or different shapes corresponding to the first label sequence and the second label sequence.

[0005] Furthermore, the box body also includes a third side wall for setting a third label sequence and a fourth side wall for setting a fourth label sequence, the third side wall is connected to the second side wall and is located on the same side of the box body; the box body is also provided with a third partition plate for defining the boundary between the second side wall and the third side wall; the fourth side wall is arranged parallel to the opposite side of the first side wall.

[0006] Furthermore, inner side walls of the plurality of side walls are provided with slots that cooperate with the plurality of first partitions and the plurality of second partitions.

[0007] Furthermore, the first tag sequence, the second tag sequence, the third tag sequence and the fourth tag sequence are respectively composed of one or more first tags, second tags, third tags and fourth tags.

[0008] Furthermore, a limiting structure cooperating with the first label, the second label, the third label and the fourth label is provided above the plurality of side walls.

[0009] Furthermore, a plurality of grooves are provided above the plurality of side walls, and the shape of the inner wall of the grooves is adapted to the outer contour of the sheet.

[0010] Furthermore, a connecting mechanism for fixing with the groove is provided at the bottom of the sheet.

[0011] Furthermore, the outer contour shape of the buffer pad is adapted to the shape of the array space unit, and the inner contour shape of the buffer pad is adapted to the shape of the reagent bottle.

[0012] Furthermore, the buffer pad is a porous sponge made of any one of polyurethane, polyethylene, polyvinyl chloride and latex.

[0013] Furthermore, the box cover comprises a cover shell, a movable door and a plurality of support plates arranged in the inner cavity of the shell cover, and a cavity for accommodating a refrigerant medium is formed between the support plates.

[0014] Beneficial effects: The utility model designs a flow antibody storage box, and sets a fluorescent label sequence and a name label sequence on the side wall of the box body, so that each antibody can be accurately and clearly placed in the corresponding position, which is convenient for experimenters to quickly find the required antibodies. In addition, the design designs different reagent slots for antibody bottles of different sizes according to antibodies produced by different antibody brands on the market, so as to prevent the internal reagents from moving during the taking process of the entire storage box and disrupting the internal partition layout. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 is a schematic diagram of the overall device structure of Example 1;

[0016] Figure 2 is a schematic diagram of the label structure of Example 1;

[0017] Figure 3 is another schematic diagram of a label structure of Example 2;

[0018] Figure 4 It is a schematic diagram of the stacking structure of the storage boxes of Example 3. DETAILED DESCRIPTION

[0019] Example 1

[0020] like Figure 1 and Figure 2 As shown, a flow antibody storage box includes a box body 1, a box cover 2 and a buffer pad 3 for wrapping a reagent bottle, the box body 1 includes a bottom plate 11 and a first side wall 13 for setting a plurality of antibody name labels 12, and a second side wall 15 adjacent to the first side wall 13 and for setting a plurality of fluorescent labels 14, a receiving cavity 16 formed by the bottom plate 11 and the first side wall 13, the second side wall 15 and the other two side walls without labels, and a plurality of first partitions 17 and a plurality of second partitions 18 are respectively arranged inside the receiving cavity 16, and the plurality of first partitions 17 and a plurality of second partitions 18 are staggered and connected to form a plurality of array space units 19 of the same or different shapes corresponding to the first side wall 13 and the second side wall 15. A limiting structure is arranged above the first side wall 13 and the second side wall 15. The first partition 17 and the second partition 18 are provided with a slot 20 for the two to match. The first partition plate 17 and the second partition plate 18 can form reagent tanks (ie, array space units 19 ) of different sizes according to different reagent bottles through the slots 20 .

[0021] The fluorescent label 14 and the antibody name label 12 are rewritable sheets made of wood, plastic, metal or other known polymer materials. A plurality of grooves 21 are provided above the first side wall 13 and the second side wall 15, and the inner wall shape of the groove 21 is adapted to the outer contour of the sheet. The bottom of the fluorescent label 14 and the antibody name label 12 is provided with a connection mechanism for fixing with the groove 21, and the limiting structure is used to limit the displacement of the fluorescent label 14 and the antibody name label 12 in the groove 21. The connection mechanism has a structure for fixing two objects in at least one direction, including but not limited to any one of the known slot fit, lock fit, thread fit, key fit, and interference fit. The fluorescent label 14 adopts a colored bottom to facilitate the distinction of different fluorescent colors, such as FITC, PE, APC, BV421, etc. in the figure. The antibody name label 12 adopts a white bottom, such as CD3, CD4, CD8, CD19, etc. in the figure. The fluorescent label and the antibody name label are set on the two side walls of the reagent box, which not only improves the accuracy and efficiency of the experiment, but also facilitates the use and management of the user, reducing errors and confusion.

[0022] The outer contour shape of the buffer pad 3 is adapted to the array space unit shape 19, and the inner contour shape of the buffer pad 3 is adapted to the shape of the reagent bottle. The buffer pad 3 is a porous sponge made of any one of polyurethane, polyethylene, polyvinyl chloride and latex. As a preferred embodiment of the present embodiment, when the reagent bottle placed is a large bottle antibody reagent bottle, such as BD antibody, large bottle ampoule, etc., the reagent tank composed of the first partition 17 and the second partition 18 will be correspondingly enlarged, and a larger buffer pad 3 can be selected at this time; when the reagent bottle placed is a small bottle antibody reagent bottle, such as Beckman antibody, ACRO antibody, small bottle ampoule, etc., the reagent tank composed of the first partition 17 and the second partition 18 will be correspondingly reduced, and a smaller buffer pad 3 can be selected at this time. Different reagent tanks are set for reagent bottles of different sizes, which not only facilitates the user to access the reagent bottle, but also maintains the internal partition layout structure and prevents the reagent bottle from moving.

[0023] The box cover 2 includes a cover shell 22, a movable door 23, and a plurality of support plates arranged in the inner cavity of the cover shell 22, and a cavity for accommodating a refrigeration medium is formed between the support plates. When using the antibody, it needs to be taken out of a refrigerator at 4°C and used at room temperature. Long-term storage at room temperature may affect the quality of the antibody. Therefore, the box cover 2 with a refrigeration medium is designed in this embodiment to effectively prevent the possibility of antibody deterioration.

[0024] Example 2

[0025] The box body of a general antibody storage box can support up to 8 fluorescent labels 14 and 12 different antibody reagent bottles. As another embodiment of the utility model, Figure 3 As shown, when there are many types of fluorescent labels 14, such as more than 16 types, the box body also includes a third side wall 20 for setting a third label sequence and a fourth side wall 21 for setting a fourth label sequence, and the third side wall 20 is connected to the second side wall 15 and is located on the same side of the box body 1; the box body 1 is also provided with a third partition 24 for defining the boundary between the second side wall 15 and the third side wall 20; the fourth side wall 21 is arranged parallel to the opposite side of the first side wall 13. Here, multiple labels in the third label sequence can be set as fluorescent labels, and multiple labels in the fourth label sequence can be antibody name labels.

[0026] Example 3

[0027] like Figure 4 As shown, as another embodiment of the present invention, when the number of antibodies is too large, one flow antibody storage box cannot accommodate too many antibodies. In this case, multiple storage boxes can be stacked.

[0028] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the protection scope of the present invention.

Claims

1. A flow cytometry antibody storage box, characterized in that: The invention comprises a box body, a box cover and a cushion pad for wrapping a reagent bottle, wherein the box body comprises a bottom plate, a plurality of side walls, and a receiving cavity formed by the bottom plate and the plurality of side walls, wherein the plurality of side walls at least comprises a first side wall for setting a first label sequence, and a second side wall adjacent to the first side wall and for setting a second label sequence, wherein the receiving cavity is provided with a plurality of first partitions and a plurality of second partitions which are parallel to the first side wall and the second side wall respectively, and wherein the plurality of first partitions and the plurality of second partitions are staggeredly connected to form a plurality of array space units of the same or different shapes corresponding to the first label sequence and the second label sequence.

2. The flow cytometry antibody storage box according to claim 1, characterized in that: The box body also includes a third side wall for setting a third label sequence and a fourth side wall for setting a fourth label sequence, the third side wall is connected to the second side wall and is located on the same side of the box body; the box body is also provided with a third partition plate for defining the boundary between the second side wall and the third side wall; the fourth side wall is arranged parallel to the opposite side of the first side wall.

3. The flow cytometry antibody storage box according to claim 1, characterized in that: The first partition plate and the second partition plate are provided with slots for matching with each other.

4. The flow cytometry antibody storage box according to claim 2, characterized in that: The first tag sequence, the second tag sequence, the third tag sequence and the fourth tag sequence are respectively composed of one or more first tags, second tags, third tags and fourth tags.

5. The flow cytometry antibody storage box according to claim 4, characterized in that: A limiting structure cooperating with the first label, the second label, the third label and the fourth label is provided above the plurality of side walls.

6. The flow cytometry antibody storage box according to claim 5, characterized in that: A plurality of grooves are arranged above the plurality of side walls, and the inner wall shapes of the grooves are adapted to the outer contour of the sheet.

7. The flow cytometry antibody storage box according to claim 6, characterized in that: The bottom of the sheet is provided with a connecting mechanism for fixing with the groove.

8. The flow cytometry antibody storage box according to claim 1, characterized in that: The outer contour shape of the buffer pad is adapted to the shape of the array space unit, and the inner contour shape of the buffer pad is adapted to the shape of the reagent bottle.

9. The flow cytometry antibody storage box according to claim 8, characterized in that: The buffer pad is a porous sponge made of any one of polyurethane, polyethylene, polyvinyl chloride and latex.

10. The flow cytometry antibody storage box according to claim 1, characterized in that: The box cover comprises a cover shell, a movable door and a plurality of support plates arranged in the inner cavity of the cover shell, and a cavity for accommodating a refrigeration medium is formed between the support plates.