Kit for detecting helicobacter pylori of human stomach

Abstract

The utility model relates to the technical field of kits, in particular to a kit for detecting human helicobacter pylori, which comprises a tube body with an open upper end and a closed bottom end, a vertical rod with a pointed upper end is vertically fixed at the center of the inner bottom surface of the tube body, a closed cover is arranged at the opening of the upper end of the tube body, and a connecting rod is fixed at the center of the lower surface of the closed cover. An inverted-cone-shaped containing piece is fixed to the lower end of the connecting rod, an opening is formed in the bottom end of the containing piece, a round elastic piece is bonded to the opening of the containing piece, the elastic piece is used for sealing the opening of the containing piece, the elastic piece is bonded to the opening of the containing piece in a tension state, and a space formed between the elastic piece and the containing piece is filled with a detection reagent. Test paper is adhered to the inner wall of the sealing cover; and when the sealing cover seals the opening of the tube body, the vertical rod has a height capable of puncturing the elastic sheet. The detection reagent can be sealed and packaged, field preparation in the prior art is not needed, and the kit is convenient to use.

Description

Technical Field

[0001] The utility model relates to the technical field of test kits, in particular to a test kit for detecting Helicobacter pylori in human stomach. Background Art

[0002] Helicobacter pylori infection is a common digestive system infection. This bacterium mainly parasitizes on the gastric mucosa of the human body. After infection, it may cause a series of symptoms, such as bad breath, acid reflux, belching, etc.

[0003] Detecting Helicobacter pylori using a test kit is a commonly used detection method. The principle is: the urease produced by Helicobacter pylori decomposes to produce products such as CO2 and NH3. The latter will cause the pH value to increase, thereby increasing the alkalinity of the gastric mucosal tissue. Therefore, the color change of the pH value can be used to determine whether the gastric mucosal tissue is infected with Helicobacter pylori.

[0004] CN 110470663 A provides a reagent and a kit for rapid detection of Helicobacter pylori in human stomach. The main structure of the kit includes: 1-result observation area; 2-test paper; 3-sampler; 4-detection reagent; 5-reactor; 6-sampling scale line; 7-top cover switch; 8-top cover. The detection reagent is a mixed solution including urea, metal nickel and solvent ethanol. The method of use is to use the sampler to add a certain volume of diluted saliva sample to the scale in the sample pool, cover the lid tightly, react for a certain time, turn it over, observe the color change of the test paper through the observation area, if there is a color change (to light red or purple red), it is a positive reaction. The defect of this patent is that the detection reagent is in liquid form and needs to be prepared and used immediately. When using it, the prepared detection reagent solution needs to be placed in the reactor for use. At the same time, the detection reagent contains volatile ethanol solvent, which affects the detection performance after volatilization. The kit does not have a accommodating function for the detection reagent, which is not conducive to industrial application. Utility Model Content

[0005] In view of the above technical problems, the utility model provides a test kit for detecting Helicobacter pylori in human stomach, which can seal and package the detection reagent, eliminating the need for on-site preparation in the prior art and making it easy to use.

[0006] The utility model provides a test kit for detecting Helicobacter pylori of human stomach, comprising a tube body with an opening at the upper end and a closed bottom end, a vertical rod with a pointed upper end being vertically fixed at the center of the inner bottom surface of the tube body, a closing cover being provided at the opening of the upper end of the tube body, a connecting rod being fixed at the center of the lower surface of the closing cover, an inverted cone-shaped containing piece being fixed at the lower end of the connecting rod, the bottom end of the containing piece being opened, a circular elastic sheet being bonded to the opening of the containing piece, the elastic sheet being used for closing the opening of the containing piece, and the elastic sheet being bonded to the opening of the containing piece in a tension state, a detection reagent being filled in a space formed between the elastic sheet and the containing piece, and a test paper being bonded to the inner wall of the closing cover; when the closing cover closes the opening of the tube body, the vertical rod has a height capable of piercing the elastic sheet.

[0007] Furthermore, the closure cover is provided with a plurality of hollow observation holes, so that the color change of the test paper can be observed through the observation holes.

[0008] Furthermore, an annular sealing gasket is bonded on the inner wall of the closing cover, and the sealing gasket is located on the periphery of the test paper, so as to improve the sealing performance of the closing cover.

[0009] Furthermore, the elastic sheet is made of rubber, and the thickness of the elastic sheet is 0.1-0.5 mm. The purpose is that the elastic sheet is thin, and under the condition of tension, the solution is punctured and ruptured to release the detection reagent.

[0010] The beneficial effects of the utility model are:

[0011] (1) The detection reagent of the utility model is sealed and stored in the container, which solves the technical defect that the detection reagent needs to be prepared on the spot. In addition, under the closed condition, the ethanol solvent will not evaporate, which reduces the impact on the detection performance and improves the stability of the detection effect.

[0012] (2) When the utility model detects a sample, the sample is placed in the tube body, and then the cover body is closed. The vertical rod with a sharp tip will pierce the elastic sheet, and the ruptured part will escape under the action of elastic tension. After the detection reagent escapes, it will mix and react with the sample. The color change of the test paper can be observed to make a judgment. The operation is convenient and easy to apply in industry. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] In order to more clearly illustrate the technical solutions in the embodiments of the utility model or the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, for ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0014] Figure 1 This is a schematic structural diagram of Example 1 of the utility model.

[0015] Figure 2 for Figure 1 Enlarged view of the layout inside the middle P circle.

[0016] Figure 3 for Figure 1 A magnified view of the layout within the middle Q circle.

[0017] Figure 4 It is the force state diagram of the elastic sheet.

[0018] Figure 5 This is the usage status diagram of the utility model

[0019] In the figure, 1-closing cover, 2-connecting rod, 3-tube body, 4-receiving member, 5-vertical rod, 6-test paper, 7-observation hole, 8-elastic sheet, 9-elastic sheet. DETAILED DESCRIPTION

[0020] In order to enable those skilled in the art to better understand the technical solutions in the present invention, the following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work should fall within the scope of protection of the present invention. Example

[0021] like Figure 1-Figure 3 The utility model provides a test kit for detecting Helicobacter pylori in human stomach, comprising a tube body 3 with an opening at the upper end and a closed bottom end, a vertical rod 5 with a pointed upper end is vertically fixed at the center of the inner bottom surface of the tube body 3, a closing cover 1 is provided at the opening of the upper end of the tube body 3, a connecting rod 2 is fixed at the center of the lower surface of the closing cover 1, an inverted cone-shaped receiving member 4 is fixed at the lower end of the connecting rod 2, the receiving member 4 has an opening at the bottom end, a circular elastic sheet 8 is bonded to the opening of the receiving member 4, the elastic sheet 8 is used to close the opening of the receiving member 4, and the elastic sheet 8 is bonded to the opening of the receiving member 4 in a tension state, and a detection reagent 9 is filled in the space formed between the elastic sheet 8 and the receiving member 4, and the detection reagent 9 is a mixed solution including urea, metal nickel and solvent ethanol, and a test paper 6 is bonded to the inner wall of the closing cover 1; when the closing cover 1 closes the opening of the tube body 3, the vertical rod 5 has a height that can pierce the elastic sheet 8.

[0022] The closing cover 1 is provided with a plurality of hollow observation holes 7. An annular sealing gasket is bonded to the inner wall of the closing cover 1, and the sealing gasket is located at the periphery of the test paper 6.

[0023] The elastic sheet 8 is made of rubber and has a thickness of 0.2 mm. Figure 4, shows the force state diagram of the elastic sheet 8. In the figure, the circular part of the elastic sheet 8 is taken as the center, and the center is subjected to tension that is dispersed and pulled toward the circumference of the elastic sheet 8, so that the elastic sheet 8 is in a tension state when bonded. The effect is that when the pointed part pierces the center, a larger escape port is formed in the center of the elastic sheet 8 under the action of tension, which is conducive to the escape of the detection reagent 9.

[0024] The method of using the utility model is as follows: take 1 mL of saliva of a suspected patient, put it into the tube body 3 after dilution, and cover it with the closing cover 1. At this time, the vertical rod 5 with a pointed upper end pierces the center of the elastic sheet 8, and a larger escape port is formed at the center of the elastic sheet 8 under the action of tension, and the detection reagent 9 escapes and mixes with the saliva sample to react. If the escape is not complete, the tube body 3 can be shaken to promote the escape of the detection reagent 9. During the reaction, the closing cover 1 is pressed by hand to turn the tube body 3 upside down, and the reaction liquid contacts the test paper 6. The test paper 6 is obtained by dipping the filter paper in the phenolphthalein reagent and drying it. If the test paper 6 changes color (changes to light red), it is positive, proving that the patient is a Helicobacter pylori patient.

[0025] Although the present invention is described in detail by referring to the accompanying drawings and in combination with the preferred embodiments, the present invention is not limited thereto. Without departing from the spirit and essence of the present invention, a person skilled in the art may make various equivalent modifications or substitutions to the embodiments of the present invention, and these modifications or substitutions shall be within the scope of the present invention. Any person skilled in the art who is familiar with the present technical field may easily think of changes or substitutions within the technical scope disclosed in the present invention, and these shall be within the scope of protection of the present invention.

Claims

1. A kit for detecting Helicobacter pylori in human stomach, characterized in that: It comprises a tube body with an opening at the upper end and a closed bottom end, a vertical rod with a pointed upper end is vertically fixed at the center of the inner bottom surface of the tube body, a closing cover is provided at the opening of the upper end of the tube body, a connecting rod is fixed at the center of the lower surface of the closing cover, an inverted cone-shaped container is fixed at the lower end of the connecting rod, the bottom end of the container is open, a circular elastic sheet is bonded to the opening of the container, the elastic sheet is used to close the opening of the container, and the elastic sheet is bonded to the opening of the container in a tension state, the space formed between the elastic sheet and the container is filled with detection reagent, and a test paper is bonded to the inner wall of the closing cover; when the closing cover closes the opening of the tube body, the vertical rod has a height that can pierce the elastic sheet.

2. The kit for detecting Helicobacter pylori in human stomach according to claim 1, characterized in that: The closing cover is provided with a plurality of hollow observation holes.

3. The kit for detecting Helicobacter pylori in human stomach according to claim 1, characterized in that: An annular sealing gasket is bonded on the inner wall of the closing cover, and the sealing gasket is located on the periphery of the test paper.

4. The kit for detecting Helicobacter pylori in human stomach according to claim 1, characterized in that: The elastic sheet is made of rubber, and the thickness of the elastic sheet is 0.1-0.5 mm.

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