Equipment for determining semi-solid phase separation

By designing a semi-solid phase separation device with magnets, anti-slip pads and sealing grooves, the problem of insufficient accuracy and repetition of the stability detection of semi-solid preparations in the prior art is solved, and a more accurate separation resistance index measurement is achieved. and stability assessment.

CN222212705UActive Publication Date: 2024-12-20SUZHOU GAOMAI PHARM CO LTD
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Patent Information

Application Number
CN202420428420.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-03-06
Publication Date
2024-12-20
Estimated Expiration
2034-03-06

AI Technical Summary

Technical Problem

The prior art is difficult to accurately determine the microstructure and stability of semi-solid preparations, which are affected by personal experience and subjective factors, and the accuracy and repetition of the detection methods are insufficient.

Method used

A device consisting of a glass cup, a base assembly and a cap assembly is designed, with a magnet and a non-slip pad, a cap assembly with a sealing groove and a leachate cone, by storing the sample under stable conditions and measuring the mass of the separation fluid, Calculate the separation resistance index to evaluate the phase separation capability.

Benefits of technology

It improves the accuracy and stability of the determination of semi-solid phase separation, enhances the stability and sealing of the equipment, facilitates operation, and meets the detection needs.

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Abstract

The utility model relates to the technical field of equipment for measuring semi-solid phase separation, and discloses equipment for measuring semi-solid phase separation, which comprises a glass cup, a base component is arranged at the bottom of the glass cup, and a top cover component is arranged at the top of the glass cup. The equipment for determining the semisolid phase separation is provided with a fixed top cover, a through groove, a fixed handle, a clamping block, a sealing groove, a sealing ring and a seepage cone, about 10g of each vaseline ointment sample is poured into the seepage cone, then the fixed top cover is placed on a glass cup, and after the vaseline ointment sample is stored for a period of time under the stable condition, the mass of components of separation liquid in the glass cup is collected; according to the utility model, the glass cup is provided with the fixed top cover, the separation resistance index (phase separation capacity) is measured and calculated under the condition that no cone is formed, the requirements of people are met, the fixed top cover can be well assembled on the glass cup through the clamping block, the sealing performance is enhanced by arranging the sealing ring, and the fixed top cover can be conveniently lifted by people by arranging the fixed handle.
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Description

Technical Field

[0001] The utility model relates to the technical field of semi-solid phase separation measuring equipment, in particular to a device for measuring semi-solid phase separation. Background Art

[0002] Characterizing the uniformity and stability of sample texture is an important quality research item for ointments. The seepage (phase separation) of semi-solid preparations is an important unstable factor, so the accuracy and repeatability of the detection method are very critical.

[0003] Practical research shows that the microstructure of the sample is difficult to observe intuitively and is affected by personal experience and subjective factors. Therefore, it is planned to be tested in the exudate cone. For example, ointments usually use white vaseline as the matrix, and the sample texture is obviously affected by the process. In order to truly reflect the stability characteristics of the product itself, we need a device for measuring semi-solid phase separation for sample testing. Utility Model Content

[0004] The purpose of the utility model is to provide a device for measuring semi-solid phase separation to solve the problems raised in the above background technology.

[0005] In order to solve the above technical problems, the utility model provides the following technical solutions: a device for measuring semi-solid phase separation, comprising a glass cup, a base assembly is arranged at the bottom of the glass cup, a top cover assembly is arranged at the top of the glass cup, and a separation liquid is arranged inside the glass cup;

[0006] The base assembly includes a fixed base, and a placement groove is opened on the top of the fixed base, a rubber pad is arranged inside the placement groove, an anti-slip pad is fixedly connected to the bottom of the fixed base, and a magnet is fixedly connected to the inner wall of the fixed base;

[0007] The top cover assembly includes a fixed top cover, and the outer wall of the fixed top cover is provided with a through groove, the outer wall of the fixed top cover is fixedly connected with a fixed handle, and the bottom of the fixed top cover is fixedly connected with a clamping block, the outer wall of the clamping block is provided with a sealing groove, and the inner wall of the sealing groove is provided with a sealing ring, and the bottom of the fixed top cover is fixedly connected with a seepage cone.

[0008] Preferably, the shape and size of the inner wall of the placement groove matches the shape and size of the outer wall of the rubber pad, and the inner wall of the placement groove fits the outer wall of the rubber pad.

[0009] Preferably, the shape and size of the placement groove match those of the glass, and one end of the glass extends into the placement groove for connection.

[0010] Preferably, there are two fixed handles, and the two fixed handles are symmetrically arranged on the fixed top cover.

[0011] Preferably, the shape and size of the outer wall of the card block matches the shape and size of the inner wall of the glass, and the outer wall of the card block fits the inner wall of the glass.

[0012] Preferably, the shape and size of the inner wall of the sealing groove matches the shape and size of the outer wall of the sealing ring, and the inner wall of the sealing groove fits the outer wall of the sealing ring.

[0013] Compared with the prior art, the beneficial effects achieved by the utility model are:

[0014] First, the utility model is provided with a fixed top cover, a through groove, a fixed handle, a clamping block, a sealing groove, a sealing ring and a seepage cone. About 10 g of each vaseline ointment sample is poured into the seepage cone, and then the fixed top cover is placed on the glass cup. After being stored for a period of time under stability conditions, the mass of the separated liquid components in the glass cup is collected and measured without a cone, and the separation resistance index (phase separation ability) is calculated, which meets people's needs. The fixed top cover can be well assembled on the glass cup through the clamping block, and the sealing ring is provided to enhance the sealing performance. The fixed handle is provided to facilitate people to lift the fixed top cover.

[0015] Second, the utility model is provided with a fixed base, a placement groove, a rubber pad, an anti-skid pad and a magnet. When the fixed base is placed on a metal table top, it can be well magnetically attracted to the metal table top through the magnet, thereby enhancing stability. When the fixed base is placed on a smooth table top, the anti-skid ability is enhanced through the anti-skid pad. Putting a glass cup into the placement groove of the fixed base makes the glass cup more stably placed and easy to use. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is a schematic diagram of the main structure of the utility model;

[0017] Figure 2 This is a schematic diagram of the structure of the fixed base and the glass cup of the utility model;

[0018] Figure 3 This is a schematic diagram of the fixed top cover and fixed handle structure of the utility model;

[0019] Figure 4 For this utility model Figure 2 Enlarged structural diagram at A in the middle.

[0020] Wherein: 1. glass cup; 2. base assembly; 201. fixed base; 202. placement groove; 203. rubber pad; 204. anti-slip pad; 205. magnet; 3. top cover assembly; 301. fixed top cover; 302. through groove; 303. fixed handle; 304. block; 305. sealing groove; 306. sealing ring; 307. seepage cone; 4. separation liquid. DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0022] See also Figure 1 , Figure 2 , Figure 3 and Figure 4 , a device for measuring semi-solid phase separation, comprising a glass 1, a base assembly 2 is arranged at the bottom of the glass 1, a top cover assembly 3 is arranged at the top of the glass 1, and a separation liquid 4 is arranged inside the glass 1;

[0023] The base assembly 2 includes a fixed base 201, and a placement groove 202 is provided on the top of the fixed base 201, a rubber pad 203 is provided inside the placement groove 202, an anti-slip pad 204 is fixedly connected to the bottom of the fixed base 201, and a magnet 205 is fixedly connected to the inner wall of the fixed base 201;

[0024] The top cover assembly 3 includes a fixed top cover 301, and the outer wall of the fixed top cover 301 is provided with a through groove 302, the outer wall of the fixed top cover 301 is fixedly connected with a fixed handle 303, and the bottom of the fixed top cover 301 is fixedly connected with a clamping block 304, the outer wall of the clamping block 304 is provided with a sealing groove 305, and the inner wall of the sealing groove 305 is provided with a sealing ring 306, and the bottom of the fixed top cover 301 is fixedly connected with a seepage cone 307.

[0025] Through the above technical scheme, about 10g of each vaseline ointment sample is poured into the seepage cone 307, and then the fixed top cover 301 is placed on the glass cup 1. After being stored for a period of time under stability conditions, the mass of the separated liquid 4 components of the glass cup 1 is collected and measured without a cone, and the separation resistance index (phase separation ability) is calculated, which meets people's needs. The fixed top cover 301 can be well assembled on the glass cup 1 through the block 304. The sealing ring 306 is provided to enhance the sealing performance. The fixed handle 303 is provided to facilitate people to lift the fixed top cover 301. When the fixed base 201 is placed on a metal table top, it can be well magnetically attracted to the metal table top through the magnet 205, thereby enhancing stability. When the fixed base 201 is placed on a smooth table top, the anti-slip ability is enhanced by the anti-slip pad 204. The glass cup 1 is placed in the placement groove 202 of the fixed base 201, so that the glass cup 1 is placed more stably and convenient for use.

[0026] Specifically, the shape and size of the inner wall of the placement groove 202 matches the shape and size of the outer wall of the rubber pad 203 , and the inner wall of the placement groove 202 fits the outer wall of the rubber pad 203 .

[0027] Through the above technical solution, the connection effect between the placement groove 202 and the rubber pad 203 is strengthened, so that the rubber pad 203 can be well fixed on the placement groove 202.

[0028] Specifically, the shape and size of the placement groove 202 match those of the glass 1 , and one end of the glass 1 extends into the placement groove 202 for connection.

[0029] Through the above technical solution, the connection effect between the placement groove 202 and the glass 1 is strengthened. The placement groove 202 is opened according to the shape of the glass 1, so that the glass 1 can be well placed in the placement groove 202.

[0030] Specifically, there are two fixed handles 303 , and the two fixed handles 303 are symmetrically arranged on the fixed top cover 301 .

[0031] Through the above technical solution, by providing two fixed handles 303 , it is convenient for people to pull the fixed handles 303 to remove the fixed top cover 301 from the glass 1 .

[0032] Specifically, the shape and size of the outer wall of the block 304 match the shape and size of the inner wall of the glass 1 , and the outer wall of the block 304 fits the inner wall of the glass 1 .

[0033] Through the above technical solution, the connection effect between the clamping block 304 and the glass 1 is strengthened. The clamping block 304 is annular and can be well assembled in the glass 1.

[0034] Specifically, the shape and size of the inner wall of the sealing groove 305 match the shape and size of the outer wall of the sealing ring 306 , and the inner wall of the sealing groove 305 is in contact with the outer wall of the sealing ring 306 .

[0035] Through the above technical solution, the connection effect between the sealing groove 305 and the sealing ring 306 is strengthened, so that the sealing ring 306 can be well installed in the sealing groove 305, and the installation and removal of the sealing ring 306 are convenient.

[0036] When in use, first, the glass cup 1 is of 50mL capacity and has a scale on the surface. The seepage cone 307 is of 100 mesh and has an opening gap of 120μm. The fixed base 201 is placed on the table, and the anti-slip ability is enhanced by the anti-slip pad 204. The glass cup 1 is placed in the placement groove 202 of the fixed base 201. About 10g of each vaseline ointment sample is poured into the seepage cone 307, and then the fixed top cover 301 is assembled to the glass cup 1 by picking up the fixed handle 303. After storing it under stable conditions for a period of time, the mass of the 4 components of the separated liquid in the glass cup 1 is collected and measured without the cone, and the separation resistance index (phase separation ability) is calculated. This completes all the work. The content not described in detail in this specification belongs to the existing technology known to professional and technical personnel in this field.

[0037] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. An apparatus for determining semi-solid phase separation, comprising a glass cup (1), Features: A base assembly (2) is arranged at the bottom of the glass (1), a top cover assembly (3) is arranged at the top of the glass (1), and a separation liquid (4) is arranged inside the glass (1); The base assembly (2) comprises a fixed base (201), and a placement groove (202) is provided on the top of the fixed base (201), a rubber pad (203) is provided inside the placement groove (202), an anti-slip pad (204) is fixedly connected to the bottom of the fixed base (201), and a magnet (205) is fixedly connected to the inner wall of the fixed base (201); The top cover assembly (3) comprises a fixed top cover (301), wherein the outer wall of the fixed top cover (301) is provided with a through groove (302), the outer wall of the fixed top cover (301) is fixedly connected with a fixed handle (303), and the bottom of the fixed top cover (301) is fixedly connected with a clamping block (304), the outer wall of the clamping block (304) is provided with a sealing groove (305), and the inner wall of the sealing groove (305) is provided with a sealing ring (306), and the bottom of the fixed top cover (301) is fixedly connected with a seepage cone (307).

2. A device for determining semi-solid phase separation according to claim 1, Features: The shape and size of the inner wall of the placement groove (202) match the shape and size of the outer wall of the rubber pad (203), and the inner wall of the placement groove (202) fits the outer wall of the rubber pad (203).

3. A device for determining semi-solid phase separation according to claim 1, Features: The shape and size of the placement groove (202) match those of the glass (1), and one end of the glass (1) extends into the placement groove (202) for connection.

4. A device for determining semi-solid phase separation according to claim 1, Features: The number of the fixed handles (303) is two, and the two fixed handles (303) are symmetrically arranged on the fixed top cover (301).

5. A device for determining semi-solid phase separation according to claim 1, Features: The shape and size of the outer wall of the clamping block (304) match the shape and size of the inner wall of the glass (1), and the outer wall of the clamping block (304) fits the inner wall of the glass (1).

6. A device for determining semi-solid phase separation according to claim 1, Features: The shape and size of the inner wall of the sealing groove (305) match the shape and size of the outer wall of the sealing ring (306), and the inner wall of the sealing groove (305) fits the outer wall of the sealing ring (306).