Pipetting workstation

By adopting adjustable pipetting mechanism and vehicle assembly in the pipetting workstation, the accuracy and stability problems caused by position deviation of the pipetting arm are solved, and efficient pipetting and waste liquid treatment is achieved, suitable for multi-spec containers.

CN222219627UActive Publication Date: 2024-12-24SHANGHAI YESTERDAY NON LAB EQUIP CO LTD
View PDF 0 Cites 2 Cited by

Patent Information

Application Number
CN202420950836.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-06
Publication Date
2024-12-24
Estimated Expiration
2034-05-06

AI Technical Summary

Technical Problem

After long-term use of existing pipetting workstations, the position of the pipetting arm will be deviated, resulting in reduced pipetting accuracy and stability, and the inability to systematically perform pipetting and waste liquid treatment.

Method used

A pipetting workstation consisting of a pipetting mechanism, a frame and an adjustment mechanism is designed to adjust the position of the pipetting gun through moving components in the X-direction, Y-direction, and Z-direction, and combine the vehicle assembly and the waste box to achieve accurate pipetting. and waste liquid treatment.

Benefits of technology

It improves pipetting accuracy and stability, and realizes system pipetting and waste liquid treatment. It is suitable for containers of different specifications, reducing the risk of contamination.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN222219627U_ABST
    Figure CN222219627U_ABST
Patent Text Reader

Abstract

The utility model provides a pipetting workstation and relates to the technical field of medical instruments. Comprising a base, a pipetting device, a carrier assembly and a waste box, the pipetting device comprises a rack, a pipetting mechanism and an adjusting mechanism, the rack is arranged on the upper end face of the base, the pipetting mechanism is installed on a supporting bottom plate of the rack, and the pipetting mechanism comprises an X-direction moving assembly, a Y-direction moving assembly and a Z-direction moving assembly; the first end of the Y-direction moving assembly is fixedly connected to the X-direction moving assembly, the Z-direction moving assembly is movably connected to the Y-direction moving assembly in the Y direction, and the pipette is movably connected to the Z-direction moving assembly in the Z direction; the adjusting mechanism is connected with the second end of the Y-direction moving assembly so as to adjust the Y-direction moving assembly to be in a horizontal state; the carrier assembly and the waste box are arranged on the supporting bottom plate, the carrier assembly is used for containing a container, and the waste box is used for containing waste. According to the pipetting workstation, the pipetting precision and the pipetting stability can be improved, and pipetting and waste liquid treatment can be systematically completed.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The utility model relates to the technical field of medical equipment, in particular to a liquid transfer workstation. Background Art

[0002] In the process of genetic testing and embryo cultivation, liquid preparation and pipetting are required. Currently, pipetting is achieved through a pipetting workstation.

[0003] Existing pipetting workstations generally include a pipette gun and a pipette arm. The pipette gun is installed on the pipette arm for pipetting. During the pipetting process, the pipette arm moves to drive the pipette gun to pipette to containers at different positions according to the placement of the reagent containers. Although this pipetting device can achieve multi-directional liquid displacement, after long-term use, the position of the pipette arm will deviate due to the influence of multiple factors such as load and usage time, resulting in reduced pipetting accuracy and stability of the pipetting workstation, and the inability to systematically perform pipetting and waste liquid treatment. Utility Model Content

[0004] The utility model aims to provide a liquid transfer workstation, which can improve the liquid transfer accuracy and liquid transfer stability, and systematically complete liquid transfer and waste liquid treatment.

[0005] To achieve this purpose, the utility model adopts the following technical solutions:

[0006] Liquid handling station, including:

[0007] Base;

[0008] A pipetting device, the pipetting device comprises a frame, a pipetting mechanism and an adjustment mechanism, the frame is arranged on the upper end surface of the base, the pipetting mechanism is installed on the supporting bottom plate of the frame, the pipetting mechanism comprises an X-direction moving component, a Y-direction moving component and a Z-direction moving component, the first end of the Y-direction moving component is fixedly connected to the X-direction moving component, the Z-direction moving component is movably connected to the Y-direction moving component along the Y direction, and the pipetting gun is movably connected to the Z-direction moving component along the Z direction; the adjustment mechanism is connected to the second end of the Y-direction moving component to adjust the Y-direction moving component to be in a horizontal state;

[0009] A carrier assembly, disposed on the supporting bottom plate, for holding containers;

[0010] The waste box is arranged on the supporting bottom plate and is used for containing waste.

[0011] As a further technical solution, the carrier assembly includes a carrier base plate and a carrier frame, the carrier base plate is provided with a plurality of carrier positioning holes at intervals, the carrier frame is connected to the carrier base plate through the corresponding carrier positioning holes, the carrier base plate is connected to the supporting base plate, and the carrier frame is used to hold containers.

[0012] As a further technical solution, a waste positioning hole and a plurality of installation positioning holes are provided on the support base plate, the carrier base plate is connected to the support base plate through the corresponding installation positioning holes, and the waste positioning holes are used to position the waste box.

[0013] As a further technical solution, a top plate is provided on the top of the frame, and the liquid transfer workstation further comprises a filtering device, and the filtering device is provided on a side of the top plate away from the frame;

[0014] And / or, the liquid transfer workstation further comprises a sterilization device, and the sterilization device is arranged on a side of the top plate close to the frame.

[0015] As a further technical solution, the pipetting workstation further includes a power supply, the base is provided with a storage piece, and the power supply is arranged in the storage piece.

[0016] As a further technical solution, the pipetting workstation further comprises a vertically lifting and hovering door panel and three closed door panels, and the vertically lifting and hovering door panel and the three closed door panels are respectively arranged around the frame.

[0017] As a further technical solution, the pipetting mechanism includes an X-direction moving component, and the adjustment mechanism includes an adjusting component and a connecting component;

[0018] The X-direction moving component is movably connected to the supporting base plate along the X-direction, the first end of the Y-direction moving component is fixedly connected to the X-direction moving component, the Z-direction moving component is movably connected to the Y-direction moving component along the Y-direction, and the pipette gun is movably connected to the Z-direction moving component along the Z-direction;

[0019] A support column extending along the Z direction is provided on the support bottom plate, the adjustment component is movably connected to the support column along the Z direction, the connection component is movably connected to the adjustment component along the X direction and is connected to the second end of the Y direction moving component, so that the Y direction moving component is in a horizontal state.

[0020] As a further technical solution, two support columns are arranged on the support bottom plate at intervals along the X direction, and the adjustment assembly includes an adjustment beam extending along the X direction and two adjustment members;

[0021] The end surfaces of the two support columns that are close to each other are each provided with a slide groove extending along the Z direction, the two adjustment members are fixedly connected to the two ends of the adjustment beam, and are respectively slidably connected to the corresponding slide grooves, and each of the adjustment members is correspondingly provided with an adjustment drive member and an adjustment limit member.

[0022] As a further technical solution, the connecting component includes a connecting member and two support wheels, the connecting member is fixedly connected to the Y-direction moving component, the two support wheels are movably arranged on the connecting member at intervals along the Z direction, and cooperate with the connecting member to form a connecting space, the adjusting beam passes through the connecting space, and the outer peripheral wall of the support wheel is provided with a groove that cooperates with the support wheel.

[0023] As a further technical solution, the pipetting device further includes an intelligent control component, which includes a level sensor and a controller. The level sensor is arranged on the pipetting mechanism, and the controller is connected to the level sensor and the adjustment mechanism.

[0024] Compared with the prior art, the liquid transfer workstation provided by the utility model has the following technical advantages:

[0025] 1. Since a pipetting device is provided in the pipetting workstation, the pipetting device includes a pipetting mechanism, a frame and an adjustment mechanism, a pipette gun used for pipetting is installed on a Z-direction moving assembly, an adjustment mechanism is provided on the frame, and the adjustment mechanism is connected to the Y-direction moving assembly, and the base provides support for the pipetting device; the pipetting mechanism can adjust the relative position of the pipette gun and the frame along the X direction, the Y direction and the Z direction according to the actual position of the container, so that the pipette gun can accurately move the target liquid into the target container; in the process of the pipetting mechanism adjusting the relative position of the pipette gun and the frame, since the adjustment mechanism is provided on the frame and connected to the pipetting mechanism, the adjustment mechanism can adjust the relative position of the pipette mechanism and the frame by adjusting the relative position of itself and the frame, so that the pipette mechanism is in a horizontal state, thereby improving the accuracy and stability of the pipetting mechanism driving the pipette gun in the process of pipetting.

[0026] 2. Since the carrier assembly for holding containers and the waste box for holding waste are arranged on the support bottom plate, the carrier assembly can be used to hold containers of different specifications for specific medical operations. The waste box is used to hold waste generated during the pipetting process to avoid contaminating the container and the liquid in the container, thereby facilitating the pipetting workstation to perform systematic pipetting and waste liquid treatment. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 It is a structural schematic diagram of a liquid transfer workstation provided by an embodiment of the utility model;

[0028] Figure 2It is a partial structural schematic diagram of a liquid transfer workstation provided by an embodiment of the utility model;

[0029] Figure 3 yes Figure 2 A partial enlarged view of the middle A;

[0030] Figure 4 It is a structural schematic diagram of the regulating mechanism in the liquid transfer device provided in an embodiment of the utility model;

[0031] Figure 5 It is a structural schematic diagram of a carrier bottom plate in a liquid transfer workstation provided by an embodiment of the utility model;

[0032] Figure 6 It is a structural schematic diagram of a supporting bottom plate in a liquid transfer workstation provided by an embodiment of the utility model;

[0033] Figure 7 It is an enlarged view of a part of the structure of the liquid transfer workstation provided by the embodiment of the utility model;

[0034] Figure 8 It is a schematic structural diagram of another embodiment of the liquid transfer workstation provided by the embodiment of the utility model.

[0035] In the figure:

[0036] 100, base; 110, storage part;

[0037] 200, liquid transfer device; 210, frame; 211, support bottom plate; 2110, guide member; 2111, waste material positioning hole; 2112, installation positioning hole; 212, support column; 2121, slideway; 213, top plate; 220, liquid transfer mechanism; 221, X-direction moving component; 222, Y-direction moving component; 223, Z-direction moving component; 2231, fixed frame; 230, adjustment mechanism; 231, adjustment component; 2311, adjustment beam; 2312, adjustment member; 232, connection component; 2321, connection member; 2322, support wheel; 233, telescopic support rod; 234, adjustment slot;

[0038] 300, carrier assembly; 310, carrier bottom plate; 311, carrier positioning hole; 320, carrier frame;

[0039] 400, waste box;

[0040] 500. Filtering device;

[0041] 600. Sterilization device;

[0042] 700, power supply;

[0043] 800. Vertical lifting and hovering door panel. DETAILED DESCRIPTION

[0044] The present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It is to be understood that the specific embodiments described herein are only used to explain the present invention, rather than to limit the present invention. It should also be noted that, for ease of description, only the parts related to the present invention, rather than all structures, are shown in the accompanying drawings.

[0045] In the description of the present invention, unless otherwise clearly specified and limited, the terms "connected", "connected", and "fixed" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0046] In the present utility model, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may include that the first and second features are in direct contact, or may include that the first and second features are not in direct contact but are in contact through another feature between them. Moreover, a first feature being "above", "above" and "above" a second feature includes that the first feature is directly above and obliquely above the second feature, or simply indicates that the first feature is higher in level than the second feature. A first feature being "below", "below" and "below" a second feature includes that the first feature is directly below and obliquely below the second feature, or simply indicates that the first feature is lower in level than the second feature.

[0047] In the description of this embodiment, the terms "upper", "lower", "right", etc., are based on the directions or positions shown in the drawings, and are only for the convenience of description and simplified operation, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation of the present invention. In addition, the terms "first" and "second" are only used to distinguish in the description and have no special meaning.

[0048] Combination Figure 1 and Figure 2As shown, the pipetting workstation provided in this embodiment is used for transferring liquid to a target container during a medical operation. The specific pipetting workstation includes a base 100, a pipetting device 200, a carrier assembly 300 and a waste box 400. The pipetting device 200 includes a frame 210, a pipetting mechanism 220 and an adjustment mechanism 230. The frame 210 is arranged on the upper end surface of the base 100. The pipetting mechanism 220 is installed on a supporting bottom plate 211 of the frame 210. The pipetting mechanism 220 includes an X-direction moving assembly 221, a Y-direction moving assembly 222 and a Z-direction moving assembly 230. 23, the first end of the Y-direction moving component 222 is fixedly connected to the X-direction moving component 221, the Z-direction moving component 223 is movably connected to the Y-direction moving component 222 along the Y direction, and the pipette is movably connected to the Z-direction moving component 223 along the Z direction; the adjustment mechanism 230 is connected to the second end of the Y-direction moving component 222 to adjust the Y-direction moving component 222 to a horizontal state; the carrier component 300 and the waste box 400 are both arranged on the supporting bottom plate 211, the carrier component 300 is used to hold containers, and the waste box 400 is used to hold waste.

[0049] Since a pipetting device 200 is provided in the pipetting workstation, the pipetting device 200 includes a pipetting mechanism 220, a frame 210 and an adjustment mechanism 230, a pipetting gun for pipetting is installed on a Z-direction moving component 223, an adjustment mechanism 230 is provided on the frame 210, and the adjustment mechanism 230 is connected to the Y-direction moving component 222, and the base 100 provides support for the pipetting device 200; the pipetting mechanism 220 can adjust the relative position of the pipetting gun and the frame 210 along the X direction, the Y direction, and the Z direction according to the actual position of the container. The pipette gun can accurately move the target liquid into the target container; in the process of the pipette mechanism 220 adjusting the relative position of the pipette gun and the frame 210, since the adjustment mechanism 230 is arranged on the frame 210 and connected to the pipette mechanism 220, the adjustment mechanism 230 can adjust the relative position between itself and the frame 210 to achieve the adjustment of the relative position of the pipette mechanism 220 and the frame 210, so that the pipette mechanism 220 is in a horizontal state, thereby improving the accuracy and stability of the pipette gun driven by the pipette mechanism 220 during the pipetting process.

[0050] Since the carrier assembly 300 for holding containers and the waste box 400 for holding waste are provided on the support base plate 211, the carrier assembly 300 can be used to hold containers of different specifications for specific medical operations. The waste box 400 is used to hold waste generated during the pipetting process to avoid contaminating the container and the liquid in the container, thereby facilitating the pipetting workstation to perform systematic pipetting and waste liquid treatment.

[0051] In addition, in this embodiment, the frame 210 is fixedly connected to the upper end surface of the base 100 through a threaded connector to ensure the connection strength and stability between the two.

[0052] Preferably, the pipetting workstation also includes a carrier assembly 300, the carrier assembly 300 includes a carrier base plate 310 and a carrier frame 320, a plurality of carrier positioning holes 311 are spaced apart on the carrier base plate 310, the carrier frame 320 is connected to the carrier base plate 310 through the corresponding carrier positioning holes 311, the carrier base plate 310 is connected to the supporting base plate 211, and the carrier frame 320 is used to hold containers.

[0053] Specific combination Figure 1 , Figure 2 and Figure 5 As shown, by connecting carrier frames 320 of different specifications to carrier positioning holes 311 at different positions, the stability of the carrier frame 320 connected to the support base plate 211 is ensured, and the relative position of the carrier frame 320 on the support base plate 211 is changed. At the same time, carrier frames 320 of different specifications can also be used to accommodate containers of different specifications to facilitate specific medical operations. In addition, a handle can be provided on the carrier frame 320 to facilitate the disassembly and removal of the carrier frame 320.

[0054] Preferably, the pipetting workstation also includes a waste box 400, and a waste positioning hole 2111 and a plurality of installation positioning holes 2112 are provided on the support base plate 211, and the carrier base plate 310 is connected to the support base plate 211 through the corresponding installation positioning holes 2112, and the waste positioning hole 2111 is used to position the waste box 400.

[0055] Specific combination Figure 1 , Figure 2 and Figure 6 As shown, a plurality of installation positioning holes 2112 are arranged at intervals on the support base plate 211, and installation positioning holes 2112 are arranged on the carrier base plate 310 corresponding to the support base plate 211. Through the installation positioning holes 2112, the carrier base plate 310 is installed on the support base plate 211 to facilitate the pipetting and liquid addition operations. The waste positioning hole 2111 is used to position the waste box 400, and the waste box 400 is used to accommodate waste generated during the pipetting process to avoid contaminating the container and the liquid in the container. In addition, the support base plate 211 is also provided with a functional carrier installation hole, and a carrier with specific functions is installed according to actual needs to meet the needs of current medical operations.

[0056] Preferably, the pipetting workstation further comprises a vertically lifting and hovering door panel 800 and three closed door panels, and the vertically lifting and hovering door panel 800 and the three closed door panels are respectively arranged around the frame 210 .

[0057] Specific combination Figure 1As shown, one side of the frame 210 near the adjustment mechanism 230 is set as a vertical lifting and hovering door panel 800, and the other three sides are set as closed door panels, and in this embodiment, the closed door panels are all set as acrylic transparent panels. Before pipetting, the vertical lifting and hovering door panel 800 is opened to facilitate the operator to prepare the liquid; during the pipetting process, the vertical lifting and hovering door panel 800 is closed, and cooperates with the three closed door panels to form a sealed space to prevent the equipment from being contaminated during the pipetting process. The acrylic transparent panel makes it convenient for the operator to observe the pipetting situation of the pipetting device 200 in the sealed space.

[0058] In an optional technical solution of this embodiment, a top plate 213 is provided on the top of the frame 210, and the pipetting workstation further includes a filtering device 500, which is disposed on a side of the top plate 213 facing away from the frame 210; and / or, the pipetting workstation further includes a sterilizing device 600, which is disposed on a side of the top plate 213 close to the frame 210.

[0059] Combination Figure 1 As shown, in this embodiment, the filter device 500 is set as a HEPA filter (High Efficiency Particulate Air Filter). During the pipetting process, the HEPA filter provides a slight positive pressure for the sealed space to ensure the cleanliness of the closed space of the pipetting workstation. The sterilization device 600 is set as an ultraviolet sterilization lamp, which is used to disinfect bacteria in the closed space.

[0060] Preferably, the liquid handling workstation further comprises a power supply 700, the base 100 is provided with a storage part 110, and the power supply 700 is arranged in the storage part 110. Figures 1 to 7 As shown, the storage member 110 is configured in a drawer shape and is disposed on the side wall of the base 100. The power supply 700 provides power to the pipetting workstation to ensure the normal operation of the pipetting workstation. The drawer-shaped storage member 110 improves the integration of the pipetting workstation, thereby reducing the space volume of the pipetting workstation.

[0061] In the optional technical solution of this embodiment, the adjustment mechanism 230 includes an adjustment component 231 and a connection component 232. The pipette gun is movably connected to the Z-direction moving component 223 along the Z direction. A support column 212 extending along the Z direction is provided on the support base plate 211, the adjustment component 231 is movably connected to the support column 212, the connection component 232 is movably connected to the adjustment component 231, and is connected to the Y-direction moving component 222, so that the Y-direction moving component 222 is in a horizontal state.

[0062] Specific combination Figure 2As shown, along the X direction, a guide member 2110 is provided on the support base plate 211, the X direction moving assembly 221 includes an X driving member and an X moving plate, the Y direction moving assembly 222 includes a Y driving member and a Y moving plate, and the Z direction moving assembly 223 includes a Z driving member, a Z moving plate and a fixing frame 2231. Along the Z direction, the relative position of the adjusting assembly 231 and the support column 212 can be adjusted, and the connecting assembly 232 is movably connected to the adjusting assembly 231. Along the X direction, the relative position of the connecting assembly 232 and the adjusting assembly 231 can be adjusted; the first end of the X moving plate is slidably connected to the guide member 2110, the X moving plate is transmission-connected to the X driving member, and the X moving plate is perpendicular to the support base plate 211; the first end of the Y moving plate The second end of the X movable plate is fixedly connected to the second end of the Y movable plate, and the second end of the Y movable plate is fixedly connected to the connecting assembly 232. The X driving member drives the X movable plate and the Y movable plate to change their relative positions with the supporting bottom plate 211 along the X direction. Along the Y direction, a first guide rail is arranged on the Y movable plate, the Z movable plate is movably connected to the first guide rail, and the Y driving member is drivingly connected to the Z movable plate to drive the Z movable plate to change its relative position with the supporting bottom plate 211 along the Y direction. A second guide rail is arranged on the Y movable plate along the Z direction, and the fixed frame 2231 is movably connected to the second guide rail. The pipette gun is detachably connected to the fixed frame 2231, and the Z driving member is drivingly connected to the fixed frame 2231 to drive the fixed frame 2231 to change its relative position with the supporting bottom plate 211 along the Z direction.

[0063] According to the pipetting requirements, the pipette gun is installed on the fixed frame 2231, the X-driving member is started, the X-driving member drives the X-moving plate and the Y-moving plate to move along the X direction, and / or the Y-driving member is started, the Y-driving member drives the Z-moving plate to move along the Y direction, and / or the Z-driving member is started, the Z-driving member drives the fixed frame 2231 to move along the Z direction, thereby changing the spatial position of the pipette gun in the X direction, and / or the Y direction, and / or the Z direction, so as to place the target liquid in the target container through the pipette gun. And because the second end of the Y-moving plate is fixedly connected to the connecting component 232, when the position of the Y-moving plate deviates and is in a non-horizontal state, the relative position of the adjusting component 231 and the supporting column 212 in the Z direction is changed to provide support for the second end of the Y-moving plate, and eliminate the deviation, so that the Y-moving plate is in a horizontal state again, so as to ensure the accuracy and stability of the Z-moving plate when sliding along the first guide rail, thereby improving the pipetting accuracy and pipetting stability.

[0064] In addition, in this embodiment, the guide member 2110 is configured as a guide convex rail or a guide groove, and the first end of the X moving plate is configured corresponding to the guide member 2110. In this embodiment, in order to improve the strength of the liquid transfer mechanism 220, it is configured as an X moving plate, a Y moving plate and an X moving plate, and can also be configured as an X moving rod, a Y moving rod and an X moving rod, or an X moving column, a Y moving column and an X moving column according to actual needs.

[0065] Preferably, two support columns 212 are arranged on the support base plate 211 at intervals along the X direction, and the adjustment component 231 includes an adjustment beam 2311 and two adjustment members 2312; the two adjustment members 2312 are fixedly connected to the two ends of the adjustment beam 2311 and are respectively connected to the two support columns 212, and at least one adjustment member 2312 is movably connected to the support column 212 along the Z direction, and the connecting component 232 is movably connected to the adjustment beam 2311.

[0066] Specific combination Figure 3 It is shown that in this embodiment, the adjustment beam 2311 is connected to the support column 212 by sliding to change the relative position of the adjustment beam 2311 and the support column 212, so that the Y movable plate is in a horizontal state. Specifically, the end surfaces of the two support columns 212 that are close to each other are both provided with a slide groove 2121 extending along the Z direction, and the two adjustment members 2312 are provided with sliding protrusions corresponding to the slide grooves 2121, and the adjustment members 2312 are slidably connected to the corresponding slide grooves 2121 through the sliding protrusions; by changing the relative position of the sliding protrusions in the slide grooves 2121, the relative position of the adjustment beam 2311 and the support column 212 is changed. The width of the bottom wall of the chute 2121 is greater than the width of the open end of the chute 2121, for example, it is set to a dovetail groove shape, a trapezoidal shape or a "⊥" shape, and the shape of the sliding protrusion is set corresponding to the chute 2121; in this way, during the position adjustment process, the chute 2121 has a guiding effect on the sliding protrusion, and after the adjustment is completed, the chute 2121 has a limiting effect on the sliding protrusion, avoiding the situation where the adjustment beam 2311 and the support column 212 are separated from each other in the X and Y directions, thereby further improving the adjustment stability. In addition, an adjustment limit assembly is set corresponding to each adjustment member 2312, and the adjustment limit assembly is closed after the position adjustment is completed to limit the current relative position of the adjustment beam 2311 and the support column 212, thereby further improving the pipetting accuracy and pipetting stability.

[0067] In addition, in order to improve the convenience and accuracy of position adjustment, each adjusting member 2312 is correspondingly provided with an adjusting drive assembly (not shown in the figure). Specifically, the adjusting drive assembly includes a chain, a sprocket and a sprocket drive motor, a sprocket is arranged on the support column 212, the chain is connected to the sprocket by transmission, and is fixedly connected to the corresponding adjusting member 2312. When it is necessary to adjust the relative position of the adjusting beam 2311 and the support column 212, the sprocket is started, and the chain drives the corresponding adjusting member 2312 to rise or fall to achieve position adjustment. A guide wheel can also be arranged on the support column 212, the middle part of the chain is connected to the guide wheel by transmission, and the guide wheel guides the corresponding chain to run; and limits the relative position between the corresponding chain and the corresponding support column 212; ensure that the lifting and lowering of the adjusting member 2312 is driven by the chain, and the lifting and lowering stability of the adjusting member 2312 is improved. In some other embodiments, the adjusting drive assembly can be set to a push rod motor, and the motor shaft of the push rod motor is connected to the corresponding adjusting member 2312 in rotation to drive the adjustment beam 2311 to rise and fall.

[0068] In this embodiment, the adjustment limit assembly includes a limit pin and a plurality of limit grooves, the limit pin is arranged on the adjustment member 2312 and / or the chain, and the plurality of limit grooves are arranged in the corresponding slide groove 2121 at intervals along the Z direction. After the adjustment member 2312 is adjusted to the target position, the limit pin is inserted into the corresponding limit groove to change the relative position of the adjustment member 2312 in the slide groove 2121. Alternatively, the adjustment limit assembly includes a limit rod and a plurality of limit protrusions, the plurality of limit protrusions are evenly arranged on one end face of the sprocket along the circumference of the sprocket, the limit rod is movably arranged on one side of the corresponding sprocket, and the rotation of the sprocket is limited by the limit rod abutting against different limit protrusions, thereby changing or limiting the relative position of the adjustment member 2312.

[0069] In some other embodiments, the end surfaces of the two support columns 212 that are close to each other are provided with multiple snap-in grooves evenly spaced along the Z direction, and the adjusting member 2312 is correspondingly provided with snap-in protrusions. When it is necessary to make the Y-direction moving component 222 in a horizontal state by adjusting the relative position of the adjusting beam 2311 and the support column 212, it is only necessary to manually snap the snap-in protrusions on the adjusting member 2312 into the corresponding snap-in grooves.

[0070] In this embodiment, the connecting component 232 includes a connecting member 2321 and two supporting wheels 2322. The connecting member 2321 is fixedly connected to the Y-direction moving component 222. The two supporting wheels 2322 are movably arranged on the connecting member 2321 at intervals along the Z direction, and cooperate with the connecting member 2321 to form a connecting space, and the adjusting beam 2311 passes through the connecting space.

[0071] Specific combination Figure 2 and Figure 4As shown, the two support wheels 2322 are connected to the connecting member 2321 by rotating at intervals along the Z direction, and the adjusting beam 2311 passes through the two support wheels 2322, so that the connecting assembly 232 is movably connected to the adjusting beam 2311, and the connecting member 2321 is fixedly connected to the second end of the Y movable plate; with the change of the relative position of the adjusting beam 2311 in the Z direction, the Y movable plate is in a horizontal state, and when the X driving member drives the X movable plate and the Y movable plate to move along the X direction, with the rolling of the two support wheels 2322, the relative position of the connecting assembly 232 and the adjusting beam 2311 is changed, so as to ensure the movement consistency of the two ends of the Y movable plate, and further improve the operation stability and operation accuracy of the pipetting mechanism 220.

[0072] Preferably, the outer peripheral wall of the support wheel 2322 is configured as a curved surface that is recessed toward the center of the support wheel 2322 .

[0073] Specific combination Figure 4 As shown, in this embodiment, the adjusting beam 2311 is set as a cylindrical beam, and the outer peripheral walls of the two supporting wheels 2322 are set as curved surfaces that are recessed toward the center of the supporting wheels 2322. This allows the connecting component 232 to be movably connected to the adjusting beam 2311, while limiting the relative position of the adjusting beam 2311 and the connecting component 232 in the Y direction, thereby preventing the adjusting beam 2311 from detaching from between the two supporting wheels 2322, and further improving the operating stability of the pipetting mechanism 220.

[0074] In some other embodiments, the connecting assembly 232 includes a connecting sleeve, which is fixedly connected to the Y-direction moving assembly 222 and sleeved on the adjusting beam 2311. When the X-driving member drives the X-moving plate and the Y-moving plate to move along the X-direction, the connecting sleeve slides on the adjusting beam 2311, which can ensure the consistency of movement of the two ends of the Y-moving plate and prevent the adjusting beam 2311 from being separated from the connecting sleeve. Alternatively, a sliding groove is provided on the adjusting beam 2311 along the X-direction, the connecting assembly 232 is fixedly connected to the second end of the Y-moving plate, and a sliding block is provided corresponding to the sliding groove, and the sliding block is slidably connected in the sliding groove.

[0075] In some other embodiments, the connecting assembly 232 includes a gear and a rack, the rack extends along the X direction and is arranged on the adjustment beam 2311, the gear meshes with the rack, and is transmission-connected with the Y-direction moving assembly 222, and a gear driving member is correspondingly arranged on the gear. The rack is arranged on the upper end surface of the adjustment beam 2311, the gear and the rack are meshed, and the gear driving member is transmission-connected with the gear. The gear driving member operates to drive the active gear to rotate, thereby meshing with the passive gear and the rack, and the X moving plate and the Y moving plate cooperate with the X driving member along the X direction to change the relative position of the X moving plate and the Y moving plate in the X direction, thereby ensuring the consistency of movement of the two ends of the Y moving plate and improving the movement accuracy of the Y moving plate.

[0076] In the above embodiment, the corresponding connection components 232 are all provided with limit components. After the relative position of the connection component 232 and the adjustment beam 2311 is adjusted, the limit components limit the current relative position of the connection component 232 and the adjustment beam 2311 to ensure the subsequent use effect of the pipetting device 200. Specifically, the limit components can be provided with two limit buckles, and both limit buckles can be detachably connected to the adjustment beam 2311. After the relative position of the connection component 232 and the adjustment beam 2311 is adjusted, the two limit buckles are respectively provided on both sides of the connection component 232 and are both connected to the adjustment beam 2311, so as to prevent the connection component 232 from shifting along the X direction on the adjustment beam 2311.

[0077] Preferably, the pipetting device 200 further includes an intelligent control component, which includes a level sensor and a controller. The level sensor is disposed on the pipetting mechanism 220 , and the controller is connected to the level sensor and the adjustment mechanism 230 .

[0078] Specifically, the horizontal sensor is arranged on the Y movable plate, and is used to monitor the real-time horizontal state of the Y movable plate and transmit it to the controller. When the horizontal sensor detects that the Y movable plate is in a non-horizontal state, the adjustment signal is transmitted to the controller. The controller receives the adjustment signal and sends an adjustment instruction to the adjustment drive component. The adjustment drive component operates according to the received adjustment instruction to drive the adjustment member 2312 and the adjustment beam 2311 to rise and fall, so that the Y movable plate is adjusted to a horizontal state. After that, the horizontal sensor sends a stop signal to the controller, and the adjustment drive component stops operating, so that the adjustment member 2312, the adjustment beam 2311, and the Y movable plate remain in the current state. The intelligent control component can realize adaptive adjustment without manual operation, further improving the timeliness and adjustment accuracy of position adjustment.

[0079] In addition, in this embodiment, the pipetting mechanism 220 may also be connected to the controller to achieve linkage between the pipetting mechanism 220 and the adjustment mechanism 230 .

[0080] In some other embodiments, the adjustment mechanism 230 can also be configured as a telescopic support rod 233, a telescopic stopper and a plurality of adjustment slots 234. Figure 8As shown, a plurality of adjustment slots 234 are evenly spaced at the second end of the Y moving plate along the length direction of the Y moving plate (i.e., the Y direction), the first end of the telescopic support rod 233 is rotatably connected to the first end of the X moving plate, and the second end of the telescopic support rod 233 is engaged in the corresponding adjustment slot 234 according to actual needs, so that the telescopic support rod 233 supports the second end of the Y moving plate with the help of the X moving plate, so that the Y moving plate is in a horizontal state, that is, by changing the length of the telescopic support rod 233, the second end of the telescopic support rod 233 is engaged with different adjustment slots 234 to adjust the height of the second end of the Y moving plate, so that the Y moving plate is always in a horizontal state. The telescopic limiter can be a threaded connector, and a threaded hole is set on the telescopic support rod 233, and the overall length of the telescopic support rod 233 is limited or changed by screwing the threaded connector.

[0081] Alternatively, the adjustment mechanism 230 can also be configured as a telescopic support rod 233, a telescopic limiter and a sliding rod (not shown in the figure), the sliding rod is fixedly arranged at the second end of the Y movable plate and extends along the Y direction, the first end of the telescopic support rod 233 is rotatably connected to the first end of the X movable plate, the first end of the telescopic support rod 233 is fixedly provided with a sliding sleeve, the sliding sleeve is slidably connected to the sliding rod, the length of the telescopic support rod 233 is changed, and the sliding sleeve is slid on the sliding rod to adjust the height of the second end of the Y movable plate, so that the Y movable plate is always in a horizontal state, and the telescopic limiter can adopt a threaded connector or a buckle slot structure.

[0082] In addition, a general control system is also provided in this embodiment, and the general control system is controlled and connected with the pipetting device 200, power supply 700, filtering device 500, sterilizing device 600, frame 210 and carrier assembly 300, so as to control the adaptive operation and adjustment of the pipetting device 200, realize pipetting of various containers and various positions, improve the pipetting accuracy and efficiency, and improve the scope of application of the pipetting workstation.

[0083] Obviously, the above embodiments of the present invention are merely examples for the purpose of clearly illustrating the present invention, and are not intended to limit the implementation methods of the present invention. For those skilled in the art, various obvious changes, readjustments and substitutions can be made without departing from the scope of protection of the present invention. It is not necessary and impossible to list all implementation methods here. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention shall be included in the scope of protection of the claims of the present invention.

Claims

1. A pipetting workstation, characterized in that: include: Base (100); A liquid transfer device (200), the liquid transfer device (200) comprising a frame (210), a liquid transfer mechanism (220) and an adjustment mechanism (230), wherein the frame (210) is arranged on the upper end surface of the base (100), the liquid transfer mechanism (220) is installed on the supporting bottom plate (211) of the frame (210), the liquid transfer mechanism (220) comprises an X-direction moving component (221), a Y-direction moving component (222) and a Z-direction moving component (223), the first end of the Y-direction moving component (222) is fixedly connected to the X-direction moving component (221), the Z-direction moving component (223) is movably connected to the Y-direction moving component (222) along the Y direction, and the liquid transfer gun is movably connected to the Z-direction moving component (223) along the Z direction; the adjustment mechanism (230) is connected to the second end of the Y-direction moving component (222) to adjust the Y-direction moving component (222) to be in a horizontal state; A carrier assembly (300), disposed on the supporting base plate (211), and used for holding containers; A waste box (400) is arranged on the supporting bottom plate (211) and is used for containing waste.

2. The liquid handling workstation according to claim 1, characterized in that: The carrier assembly (300) comprises a carrier base plate (310) and a carrier frame (320); a plurality of carrier positioning holes (311) are arranged at intervals on the carrier base plate (310); the carrier frame (320) is connected to the carrier base plate (310) via the corresponding carrier positioning holes (311); the carrier base plate (310) is connected to the supporting base plate (211); and the carrier frame (320) is used to hold containers.

3. The liquid handling workstation according to claim 2, characterized in that: The support base plate (211) is provided with a waste positioning hole (2111) and a plurality of installation positioning holes (2112); the carrier base plate (310) is connected to the support base plate (211) via the corresponding installation positioning holes (2112); and the waste positioning hole (2111) is used to position the waste box (400).

4. The liquid handling workstation according to claim 1, characterized in that: A top plate (213) is disposed on the top of the frame (210), and the liquid transfer workstation further comprises a filtering device (500), wherein the filtering device (500) is disposed on a side of the top plate (213) away from the frame (210); And / or, the liquid transfer workstation further comprises a sterilization device (600), and the sterilization device (600) is arranged on a side of the top plate (213) close to the frame (210).

5. The liquid handling workstation according to claim 1, characterized in that: The liquid transfer workstation further comprises a power supply (700); the base (100) is provided with a storage part (110); and the power supply (700) is arranged in the storage part (110).

6. The liquid handling workstation according to claim 1, characterized in that: The liquid transfer workstation further comprises a vertically lifting and hovering door panel (800) and three closed door panels, wherein the vertically lifting and hovering door panel (800) and the three closed door panels are respectively arranged around the frame (210).

7. The liquid handling workstation according to claim 1, characterized in that: The adjustment mechanism (230) comprises an adjustment component (231) and a connection component (232); The supporting base plate (211) is provided with a supporting column (212) extending along the Z direction, the adjusting component (231) is movably connected to the supporting column (212) along the Z direction, the connecting component (232) is movably connected to the adjusting component (231) along the X direction, and is connected to the second end of the Y-direction moving component (222), so that the Y-direction moving component (222) is in a horizontal state.

8. The liquid handling workstation according to claim 7, characterized in that: Two support columns (212) are arranged on the support base plate (211) at intervals along the X direction, and the adjustment component (231) comprises an adjustment beam (2311) extending along the X direction and two adjustment members (2312); The end surfaces of the two support columns (212) that are close to each other are each provided with a slide groove (2121) extending along the Z direction, the two adjustment members (2312) are fixedly connected to the two ends of the adjustment beam (2311), and are respectively slidably connected to the corresponding slide grooves (2121), and each adjustment member (2312) is correspondingly provided with an adjustment driving member and an adjustment limiting member.

9. The liquid handling workstation according to claim 8, characterized in that: The connecting component (232) comprises a connecting piece (2321) and two supporting wheels (2322), wherein the connecting piece (2321) is fixedly connected to the Y-direction moving component (222), and the two supporting wheels (2322) are movably arranged on the connecting piece (2321) at intervals along the Z direction, and cooperate with the connecting piece (2321) to form a connecting space, the adjusting beam (2311) passes through the connecting space, and the outer peripheral wall of the supporting wheel (2322) is provided with a groove that cooperates with the supporting wheel (2322).

10. The liquid handling workstation according to any one of claims 1 to 9, characterized in that: The liquid transfer device (200) further comprises an intelligent control component, the intelligent control component comprising a level sensor and a controller, the level sensor being arranged on the liquid transfer mechanism (220), and the controller being connected to the level sensor and the adjustment mechanism (230).

Citation Information

Cited By

  • Pipetting workstation

    CN118268059A

  • Pipetting workstation

    CN118268059B