Coating machine
By introducing a variety of materials to the coating machine to adapt to the design, including hot and cold air drying partitions, dry film thickness detection and deviation correction devices, the problem that existing coating machines are difficult to adapt to different drug materials is solved, and a variety of drugs are realized. Effective coating and reduction of equipment investment costs.
Patent Information
- Application Number
- CN202420943198.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-30
- Publication Date
- 2024-12-31
- Estimated Expiration
- 2034-04-30
AI Technical Summary
Existing coating machines are difficult to adapt to different types of pharmaceutical materials, resulting in high equipment investment costs during the R&D process and difficult to meet the coating needs of multiple materials.
A coating machine is designed, including a drying area, a coating die head, a coating roller, a material conveying component, a slitting device and a winding component. The drying area is equipped with hot and cold air drying partitions, equipped with a dry film thickness detection device and Correction device, suitable for coating a variety of materials, including hot melt adhesive, oral dissolving film and gel.
Effective coating of a variety of pharmaceutical materials is achieved, the cost of equipment investment is reduced, the drug is deteriorated and the uneven coating of glue is applied, and the stability and reliability of the production process are improved.
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Figure CN222273682U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the field of food and medicine packaging machinery and equipment, in particular to a coating machine. Background Art
[0002] At present, injection and oral drug intake may not meet the needs of some patients. Therefore, as research progresses, a third drug intake method has gradually emerged, namely transdermal patch administration, which is to evenly coat the drug on a coil and then package it through a corresponding process. When the patient needs to use it, he only needs to apply it to the skin surface. The drug is in close contact with the skin, absorbed by the skin and then ingested by the patient to treat various diseases.
[0003] With the rapid growth of the transdermal patch market, more and more traditional and emerging pharmaceutical companies have begun to turn to the research and development of patch drugs, and the coating machine is one of the key equipment used for the experimental production of patch drug research and development. If the coating machine can meet the experimental production of multiple types of patches at the same time, it can effectively reduce the initial investment cost of patch research and development. Utility Model Content
[0004] The technical problem to be solved by the utility model is to overcome the deficiencies of the prior art and provide a coating machine which has a simple structure, can adapt to different materials, and is conducive to reducing the equipment investment cost in the research and development process.
[0005] In order to solve the above technical problems, the utility model adopts the following technical solutions:
[0006] A coating machine comprises a drying zone, one end of which is provided with a release film unwinding component, a coating die, a coating roller and a material conveying component, the coating die is arranged on the side of the coating roller, the material conveying component is connected to the coating die, the other end of the drying zone is provided with a slitting device and a winding component, and the drying zone comprises at least one hot air drying partition and at least one cold air drying partition.
[0007] As a further improvement of the above technical solution: a first film unwinding component and a film coating roller are further provided at one end of the drying zone, the film coating roller is arranged between the coating roller and the drying zone, and a film bonding device is provided between the drying zone and the slitting device.
[0008] As a further improvement of the above technical solution: a second film unwinding component is further provided at the other end of the drying area.
[0009] As a further improvement of the above technical solution: the laminating roller and the coating die head are arranged opposite to each other on both sides of the coating roller.
[0010] As a further improvement of the above technical solution: the coating machine also includes a dry film thickness detection device, and the dry film thickness detection device is arranged at the outlet of the drying area.
[0011] As a further improvement of the above technical solution: a deviation correction device is provided between the drying area and the slitting device.
[0012] As a further improvement of the above technical solution: the coating die is a slot coating die or a blade coating die.
[0013] As a further improvement of the above technical solution: the drying area includes a drying chamber, and the drying chamber is connected to an air inlet duct and an air exhaust duct.
[0014] As a further improvement of the above technical solution: an upper air outlet and a lower air outlet are provided in the drying chamber, and the upper air outlet and the lower air outlet are staggered.
[0015] As a further improvement of the above technical solution: a concentration detection component and / or a temperature detection component is provided at the inlet and the outlet of the drying zone.
[0016] Compared with the prior art, the advantages of the utility model are: the coating machine disclosed in the utility model is provided with a drying zone, which includes at least one hot air drying zone and at least one cold air drying zone, which can dry the coated hot melt adhesive, evaporate the moisture and organic solvent in the hot melt adhesive, prevent the drug from deteriorating, and avoid uneven glue overflow during the coating process and the deviation of the glue after film pressing when the glue is not dry; it can be suitable for the coating of a variety of materials, such as materials that need to be heated (orally dissolving films, solvent patches, etc.) and materials that need to be cooled (hot melt adhesives, which need to be cooled after heating). Of course, when the drying zone is not working, general materials (such as gel) can also be coated. The structure is simple and effective, which is conducive to reducing the equipment investment cost in the research and development process. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] Figure 1 It is a structural schematic diagram of the coating machine of the utility model.
[0018] The numbers in the figure represent: 1. Drying area; 2. Release film unwinding component; 3. Coating die; 4. Coating roller; 5. Material conveying component; 6. Slitting device; 7. Rewinding component; 8. First laminating film unwinding component; 9. Laminating roller; 10. Film closing device; 11. Second laminating film unwinding component; 12. Dry film thickness detection device; 13. Correction device; 14. Drying chamber; 15. Air inlet duct; 16. Exhaust duct; 17. Upper air outlet; 18. Lower air outlet. DETAILED DESCRIPTION
[0019] In the description of the present invention, it should be understood that the terms "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.
[0020] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present utility model, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.
[0021] In the present invention, unless otherwise clearly specified and limited, the terms "assemble", "connect", "connect", "fix" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0022] The present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.
[0023] Figure 1 An embodiment of the utility model is shown. The coating machine of this embodiment includes a drying zone 1. One end of the drying zone 1 is provided with a release film unwinding component 2 (such as a commonly used unwinding roller), a coating die 3, a coating roller 4 and a material conveying component 5 (preferably a conveying pump, of course, in other embodiments, other conveying methods can also be used to convey materials). The coating die 3 is arranged on the side of the coating roller 4, and the material conveying component 5 is connected to the coating die 3. The other end of the drying zone 1 is provided with a slitting device 6 and a winding component 7. The drying zone 1 includes two hot air drying partitions and one cold air drying partition. The two hot air drying partitions can be used as preheating partitions and drying partitions respectively, which can basically adapt to the coating of common materials. Of course, in other embodiments, the number of hot air drying partitions and cold air drying partitions can also be adjusted appropriately.
[0024] In the coating machine of this embodiment, the drying zone 1 can dry the coated hot melt adhesive, evaporate the moisture and organic solvent in the hot melt adhesive, prevent the drug from deteriorating, and avoid uneven glue overflow during coating and deviation after film pressing when the glue liquid is not dry; it can be suitable for coating of various materials, such as other materials that need to be heated (orally dissolving films, solvent patches, etc.) and materials that need to be cooled (hot melt adhesives, which need to be cooled after heating). Of course, when the drying zone 1 is not working, general materials (such as gel) can also be coated. The structure is simple and effective, which is conducive to reducing the equipment investment cost in the research and development process.
[0025] Furthermore, in this embodiment, a first film coating unwinding component 8 (such as a commonly used unwinding roller) and a film coating roller 9 are further provided at one end of the drying zone 1. The film coating roller 9 is provided between the coating roller 4 and the drying zone 1. A film bonding device 10 is provided between the drying zone 1 and the slitting device 6. When applying the hot melt adhesive, the release film released by the release film unwinding component 2 and the backing film released by the first film coating unwinding component 8 are laminated by the film bonding device 10 and then slit by the slitting device 6.
[0026] Furthermore, in this embodiment, a second film unwinding component 11 (such as a commonly used unwinding roller) is further provided at the other end of the drying zone 1. When applying the solvent patch, the release film released by the release film unwinding component 2 and the backing film released by the second film unwinding component 11 are laminated by the film laminating device 10, and then slit by the slitting device 6.
[0027] As a preferred embodiment, the coating roller 9 and the coating die head 3 are arranged on both sides of the coating roller 4. This layout makes the coating roller 9 and the coating die head 3 not interfere with each other, and the overall structure is compact and reasonable.
[0028] Furthermore, in this embodiment, the coating machine further includes a dry film thickness detection device 12, which is disposed at the exit of the drying zone 1. The dry film thickness detection device 12 can monitor the thickness of the film after passing through the drying zone 1, and determine whether the thickness of the film after the coating, drying and other processes meets the requirements.
[0029] Furthermore, in this embodiment, a deviation correction device 13 is provided between the drying area 1 and the slitting device 6. The deviation correction device 13 can prevent the film roll from deviating during the transmission process, which is beneficial to improving the stability and reliability of the machine.
[0030] As a preferred embodiment, the coating die 3 is a slot coating die or a blade coating die.
[0031] Furthermore, in this embodiment, the drying area 1 includes a drying chamber 14, and the drying chamber 14 is connected to an air inlet duct 15 and an air exhaust duct 16. The air inlet duct 15 can introduce hot air or cold air into the air inlet duct 15 as needed to perform hot air drying or cold air drying, and the air exhaust duct 16 is used to discharge the hot air or cold air in the drying chamber 14 and the moisture, organic solvent, etc. generated during the drying process, which is conducive to maintaining a clean environment inside the drying chamber 14.
[0032] Furthermore, in the present embodiment, an upper air outlet 17 and two lower air outlets 18 are provided in the drying chamber 14, and the upper air outlet 17 and the two lower air outlets 18 are staggered, specifically arranged in a herringbone shape. The hot air or cold air input by the air inlet duct 15 enters the drying chamber 14 through the upper air outlet 17 and the two lower air outlets 18, which is conducive to evenly distributing the hot air or cold air in the drying chamber 14, thereby ensuring a uniform drying effect.
[0033] As a preferred embodiment, concentration detection components and / or temperature detection components (not shown in the figure, for example, various sensors, probes, etc.) can be provided at the entrance and exit of the drying zone 1. The concentration detection components can detect the concentration of water and organic solvents generated during the drying process to determine the drying effect; the temperature detection components can detect whether the drying temperature meets the requirements.
[0034] The working principle of the utility model coating machine is as follows:
[0035] Orally dissolving film coating: the material is transported to the coating die 3 through the delivery pump, and the coating die 3 evenly coats the material on the release film; the release film is unwound at a uniform speed by the release film unwinding component 2, and the coating is transported to the first hot air drying partition for preheating through the coating roller 4, and then transported to the second and third hot air drying partitions for heating to volatilize the moisture and organic solvent in the material, and then the material is cut by the slitting device 6, and finally the winding is completed by the winding component 7. The deviation correction device 13 prevents the roll film from deviating during the movement, and the dry film thickness detection device 12 is used to detect the thickness of the dry film after drying.
[0036] Solvent patch coating: The material is transported to the coating die 3 through a delivery pump, and the coating die 3 evenly coats the material on the release film; the release film is unwound at a uniform speed by the release film unwinding component 2, and the coating is transported to the first hot air drying zone for preheating through the coating roller 4, and then transported to the second and third hot air drying zones for heating to volatilize the moisture and organic solvent in the material; then the material is laminated with the backing film unwound by the second laminating unwinding component 11, cut, and finally rolled up. The deviation correction device 13 prevents the roll film from deviating during movement, and the dry film thickness detection device 12 is used to detect the thickness of the dry film after drying.
[0037] Hot melt adhesive coating: The heated material is conveyed to the coating die head 3 with heating function through the heated conveying pump, and the coating die head 3 evenly coats the material on the release film; the release film is unwound at a uniform speed by the unwinding roller, passes through the coating roller 4, and then is laminated with the backing film unwound by the first laminating unwinding component 8, and then the laminated roll is conveyed to three cold air drying partitions for air cooling, and then cut, and finally completed. The deviation correction device 13 prevents the roll film from deviating during movement, and the dry film thickness detection device 12 is used to detect the thickness of the dry film after drying.
[0038] Gel coating: The material is transported to the coating die 3 through the conveying pump, and the coating die 3 evenly coats the material on the release film; the release film is unwound at a uniform speed by the unwinding roller, passes through the coating roller 4, and then is coated with the backing film unwound by the first coating unwinding component 8, and then the coated roll is cut. The deviation correction device 13 prevents the roll film from deviating during movement, and the dry film thickness detection device 12 is used to detect the coating thickness of the gel.
[0039] The coating machine of the utility model can complete the entire coating production process of orodispersible films, solvent patches, hot melt adhesives, and gel patches, and is suitable for patch research and development. As an experimental coating machine, its process parameters can be directly applied to large-scale production equipment. Due to the integration of multiple coating processes and coating methods, the initial equipment procurement investment cost can be reduced.
[0040] Although the present invention has been disclosed as a preferred embodiment, it is not intended to limit the present invention. Any technician familiar with the art can use the above disclosed technical content to make many possible changes and modifications to the technical solution of the present invention without departing from the scope of the technical solution of the present invention, or modify it into an equivalent embodiment of equivalent changes. Therefore, any simple modification, equivalent change and modification made to the above embodiments based on the technical essence of the present invention without departing from the content of the technical solution of the present invention should fall within the scope of protection of the technical solution of the present invention.
Claims
1. A coating machine, characterized in that: The invention comprises a drying zone (1), wherein one end of the drying zone (1) is provided with a release film unwinding component (2), a coating die (3), a coating roller (4) and a material conveying component (5), wherein the coating die (3) is arranged on the side of the coating roller (4), and the material conveying component (5) is connected to the coating die (3); the other end of the drying zone (1) is provided with a slitting device (6) and a winding component (7), and the drying zone (1) comprises at least one hot air drying partition and at least one cold air drying partition.
2. The coating machine according to claim 1, characterized in that: A first film unwinding component (8) and a film coating roller (9) are also provided at one end of the drying zone (1); the film coating roller (9) is provided between the coating roller (4) and the drying zone (1); and a film bonding device (10) is provided between the drying zone (1) and the slitting device (6).
3. The coating machine according to claim 2, characterized in that: A second film unwinding component (11) is also provided at the other end of the drying zone (1).
4. The coating machine according to claim 2, characterized in that: The coating roller (9) and the coating die head (3) are arranged opposite to each other on both sides of the coating roller (4).
5. The coating machine according to any one of claims 1 to 4, characterized in that: It also comprises a dry film thickness detection device (12), wherein the dry film thickness detection device (12) is arranged at the exit of the drying area (1).
6. The coating machine according to any one of claims 1 to 4, characterized in that: A deviation correction device (13) is provided between the drying area (1) and the slitting device (6).
7. The coating machine according to any one of claims 1 to 4, characterized in that: The coating die (3) is a slit coating die or a blade coating die.
8. The coating machine according to any one of claims 1 to 4, characterized in that: The drying area (1) comprises a drying chamber (14), and the drying chamber (14) is connected to an air inlet duct (15) and an air exhaust duct (16).
9. The coating machine according to claim 8, characterized in that: An upper air outlet (17) and a lower air outlet (18) are provided in the drying chamber (14), and the upper air outlet (17) and the lower air outlet (18) are arranged in a staggered manner.
10. The coating machine according to any one of claims 1 to 4, characterized in that: The inlet and the outlet of the drying zone (1) are both provided with a concentration detection component and / or a temperature detection component.
Citation Information
Cited By
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