Cryopreservation box with cold accumulation function

By setting the refrigerant and specific structure in the frozen storage box, the problem of sample temperature changes after the frozen storage box is removed from the low-temperature equipment is solved, and the continuous low-temperature storage of the frozen storage box is realized, avoiding the sample deterioration, and simplifying the structure and use process.

CN222330310UActive Publication Date: 2025-01-10ZHONGKE MEILING CRYOGENICS CO LTD
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Patent Information

Application Number
CN202421240688.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-31
Publication Date
2025-01-10
Estimated Expiration
2034-05-31

AI Technical Summary

Technical Problem

After the existing frozen storage box is removed from the low-temperature storage device, the sample temperature rises rapidly due to changes in the external ambient temperature, causing the sample to deteriorate or damage.

Method used

A frozen storage box with cooling function was designed. There are multiple holes and cavity grooves in the base, and through holes are provided on the cover plate to form a closed hollow chamber. The chamber is equipped with refrigerant and the frozen storage tube is passed. The through-hole is inserted into the hole position and stored under the cold temperature of the refrigerant to ensure that the sample remains low when the temperature changes.

Benefits of technology

It effectively avoids deterioration or damage caused by repeated large span changes in the temperature of the sample, ensuring that the sample can still maintain low temperature storage conditions after removal, with a simple structure, convenient disassembly and assembly, and a low cost.

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Abstract

The utility model discloses a cryopreservation box with a cold storage function. The cryopreservation box comprises a base, a cover plate, a box cover and cryopreservation pipes. A plurality of hole sites are distributed in the base at intervals, and a cavity groove is formed in the position, outside the hole sites, in the base. A plurality of through holes are formed in the cover plate at intervals, and the through holes are matched with the hole sites in a one-to-one correspondence mode; the cover plate covers the top of the base, the cover plate and the cavity groove are closed to form a cavity, and a cold storage agent is arranged in the cavity; the cryopreservation tube for collecting samples penetrates through the through hole and is placed in the hole site; and the box cover is arranged on the base in a covering manner. According to the cryopreservation box, the base is internally provided with the coolant for cryopreservation of the cryopreservation tube, after the cryopreservation box is taken out of the cryopreservation equipment, the coolant plays a role in continuously freezing the cryopreservation tube, it is ensured that samples are in a low-temperature preservation condition in the whole process, and the samples are prevented from going bad or being damaged due to repeated large-span temperature changes.
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Description

Technical Field

[0001] The utility model relates to the technical field of sample storage, in particular to a freezing box with a cold storage function. Background Art

[0002] Cryoboxes are often used to store and transfer samples in medical research, teaching, and clinical testing. After collecting the experimental samples, they need to be placed in cryotubes and cryoboxes for storage to facilitate subsequent experimental operations and use. When the samples need to be stored or experimentally operated in a low-temperature environment, the cryoboxes are placed in low-temperature storage equipment to achieve the effect of low-temperature preservation.

[0003] In the prior art, after the cryobox is taken out of the low-temperature storage device, it is directly exposed to the external environment. The temperature of the external environment causes the temperature of the sample in the cryobox to rise rapidly until it reaches the temperature of the external environment. Not only can it not ensure that the sample is in a low-temperature environment throughout the process, but also after the sample temperature repeatedly changes over a large span, it will accelerate the deterioration or damage of the sample. Utility Model Content

[0004] The utility model provides a freezing box with a cold storage function and better low-temperature preservation effect, which can at least solve one of the above technical problems.

[0005] In order to solve the above technical problems, the utility model adopts the following technical solutions: a cryo box with cold storage function, comprising a base, a cover plate, a box cover and a cryo tube;

[0006] A plurality of holes are arranged at intervals in the base, and a cavity is provided inside the base and outside the plurality of holes;

[0007] The cover plate is provided with a plurality of through holes at intervals, and each of the through holes is matched with each of the hole positions in a one-to-one correspondence;

[0008] The cover plate is mounted on the top of the base and is closed with the cavity to form a hollow chamber, in which a coolant is arranged;

[0009] The cryotube for collecting samples passes through the through hole and is placed in the hole;

[0010] The box cover is arranged on the base.

[0011] Furthermore, the base is a box structure without a top cover, the cover is a horizontal plate structure, and the cover is provided with flange edges along four sides, and the flange edges match with the mouth of the base.

[0012] Furthermore, the plurality of hole positions are evenly arranged in the base, and are all in the shape of a cylinder without a cap, the mouth of each hole position is flush with the mouth of the base, and the plurality of through holes are evenly arranged on the cover plate, the aperture of the through holes is consistent with the aperture of the hole positions, and the through holes are fitted and in contact with the mouth of the hole positions.

[0013] Furthermore, the cryogenic tube is a sealed sample tube, a tube plug is installed at the tube mouth, the cryogenic tube is inserted into the hole, and the tube plug extends outward from the through hole.

[0014] Furthermore, the box cover is a box body structure without a bottom cover, which is matched with the base cover, and the box body depth of the box cover is greater than the box body depth of the base, and the base cover can be arranged inside.

[0015] Furthermore, the types of the coolant are various.

[0016] The beneficial effects of the utility model are embodied in:

[0017] 1. In the utility model, a refrigerant for low-temperature preservation of the cryotube is arranged in the base. After the cryobox is taken out from the low-temperature storage device, the refrigerant plays a role in continuously freezing the cryotube, ensuring that the sample is kept in a low-temperature storage condition throughout the process, and avoiding deterioration or damage of the sample due to repeated large-span changes in temperature.

[0018] 2. In the utility model, a plurality of holes for inserting cryogenic tubes are arranged at intervals in the base, and the spaces outside the plurality of holes are connected to form a cavity. The cover plate is matched with the base cover to encapsulate the cavity to form a closed empty chamber. The refrigerant is placed in the empty chamber, and the cryogenic tubes are inserted into the holes through the through holes on the cover plate to be preserved at low temperatures by the refrigerant. The box cover arranged outside the base and the cover plate can be removed to extract any cryogenic tube without affecting the normal and continuous freezing of other cryogenic tubes.

[0019] 3. In the utility model, the freezing box has a simple structure, is convenient to assemble and disassemble, is easy to implement and use, has a low production cost, and has a good promotion prospect. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] The drawings described herein are used to provide further understanding of the present application and constitute a part of the present application. The illustrative embodiments of the present application and their descriptions are used to explain the present application and do not constitute improper limitations on the present application.

[0021] Figure 1 It is an exploded view of an embodiment of the utility model.

[0022] Figure 2 It is a cross-sectional view of the assembly of the base and the cover plate of an embodiment of the utility model.

[0023] Figure 3It is an axonometric view of the base and cover assembly of an embodiment of the utility model.

[0024] The components in the accompanying drawings are marked as follows: 1. base; 101. hole position; 102. cavity; 2. cover plate; 201. through hole; 202. flange edge; 3. box cover; 4. cryotube; 401. tube plug; 5. empty chamber. DETAILED DESCRIPTION

[0025] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. In the absence of conflict, the embodiments in this application and the features in the embodiments can be combined with each other. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model. It should be noted that if there are directional indications (such as up, down, left, right, front, back...) in the embodiments of the utility model, the directional indication is only used to explain the relative position relationship, movement, etc. between the components under a certain specific posture (as shown in the drawings). If the specific posture changes, the directional indication also changes accordingly. In addition, "multiple" refers to more than two.

[0026] See also Figure 1-2 The embodiment of the utility model provides a cryo box with a cold storage function, comprising a base 1, a cover plate 2, a box cover 3 and a cryo tube 4;

[0027] The base 1 has a plurality of holes 101 spaced apart from each other, and the base 1 has a cavity 102 disposed inside and outside the plurality of holes 101;

[0028] The cover plate 2 is provided with a plurality of through holes 201 at intervals, and each of the through holes 201 is matched with each of the hole positions 101 in a one-to-one correspondence;

[0029] The cover plate 2 is mounted on the top of the base 1 and is closed with the cavity 102 to form a hollow chamber 5, in which a refrigerant is arranged;

[0030] The cryotube 4 for collecting samples passes through the through hole 201 and is placed in the hole 101;

[0031] The box cover 3 is disposed on the base 1 .

[0032] In the utility model, a plurality of holes for inserting cryogenic tubes are arranged at intervals in the base, and the spaces outside the plurality of holes are connected to form a cavity. The cover plate is matched with the base to cover the cavity to encapsulate the cavity to form a closed empty chamber. The refrigerant is placed in the empty chamber, and the cryogenic tubes are inserted into the holes through the through holes on the cover plate to be preserved at low temperatures by the refrigerant. When the box cover arranged outside the base and the cover plate is removed, any cryogenic tube can be extracted without affecting the normal and continuous freezing of other cryogenic tubes.

[0033] See also Figure 2 and 3 In this embodiment, the base 1 is a box structure without a top cover, the cover plate 2 is a horizontal plate structure, and the cover plate 2 is provided with flange edges 202 along the four sides, and the flange edges 202 match the mouth of the base 1. With this design, the cover plate 2 is horizontally buckled on the top of the base 1, and the flange edges 202 further enhance the tightness of the assembly between the two.

[0034] See also Figure 2-3 In this embodiment, the plurality of holes 101 are evenly arranged in the base 1, and are all in the shape of a cylinder without a cap. The mouth of each hole 101 is flush with the mouth of the base 1, and the plurality of through holes 201 are evenly arranged on the cover plate 2. The aperture of the through hole 201 is consistent with the aperture of the hole 101, and the through hole 201 fits and contacts the mouth of the hole 101. With this design, the cover plate 2 fits and is installed on the top surface of the base 1 to encapsulate the cavity 102, and the empty chamber 5 forms a closed inner cavity structure. The refrigerant is injected into the empty chamber 5, and the plurality of cryotubes 4 inserted into each hole 101 are frozen at the same time.

[0035] See also Figure 1 and 3 In this embodiment, the cryotube 4 is a sealed sample tube, and a tube plug 401 is installed at the tube mouth. The cryotube 4 is inserted into the hole 101, and the tube plug 401 extends outward from the through hole 201. With this design, each cryotube 4 is independently sealed to store samples, reducing the risk of contamination and damage to samples by contamination sources. Each cryotube 4 is inserted into each hole 101 in a one-to-one correspondence, and when any cryotube 4 is extracted from the cover plate 2, the continued freezing of the remaining cryotubes 4 will not be affected.

[0036] See also Figure 1In this embodiment, the box cover 3 is a box structure without a bottom, which is matched with the base 1, and the box body depth of the box cover 3 is greater than the box body depth of the base 1, and the base 1 can be covered inside. With this design, when the box cover 3 is covered on the base 1, the cryogenic tube 4 inserted in the base 1 is also covered inside, which plays a role in sealing and protecting the cryogenic tube 4. At the same time, the box cover 3 completely covers the base 1, which plays a role in storing cold and keeping warm the cryogenic agent in the base 1. The cryogenic tube 4 can be taken out by removing the box cover 3.

[0037] See also Figure 1 In this embodiment, the types of the refrigerant are diverse. Designed in this way, the types of the refrigerant include forms, such as solid, liquid, gas, gel and other different refrigerant forms, and also include materials, including water, chemical agents and other materials. The specific types can be selected according to the sample storage requirements. For example, when the refrigerant is selected as water, the cryopreservation box is placed in a low-temperature storage device. When the temperature is as low as 0°C, the water condenses from liquid to ice and becomes solid. After the cryopreservation box is taken out of the low-temperature storage device, when the temperature is higher than 0°C, the ice dissolves from solid to water and becomes liquid. A large amount of cold energy is stored in the freezing process, and a large amount of heat energy is absorbed in the dissolving process, thereby achieving a continuous cold storage and heat preservation effect on the cryopreservation tube 4 taken out from the low-temperature storage device.

[0038] In summary, in the utility model, a refrigerant for low-temperature preservation of cryopreservation tubes is arranged in the base. After the cryopreservation box is taken out from the low-temperature storage device, the refrigerant plays a role in continuously freezing the cryopreservation tubes, ensuring that the samples are kept in low-temperature preservation conditions throughout the process, and avoiding deterioration or damage of the samples due to repeated large-scale temperature changes. Specifically, a plurality of holes for inserting cryopreservation tubes are arranged at intervals in the base, and the spaces outside the plurality of holes are connected to form a cavity. The cover plate is matched with the base cover to encapsulate the cavity to form a closed empty chamber. The refrigerant is placed in the cavity, and the cryopreservation tubes are inserted into the holes through the through holes on the cover plate and are preserved at low temperatures by the refrigerant. The box cover arranged outside the base and the cover plate can be removed to extract any cryopreservation tube without affecting the normal and continuous freezing of other cryopreservation tubes. At the same time, the cryopreservation box has a simple structure, convenient disassembly and assembly, easy implementation and use, low manufacturing cost, and good promotion prospect.

[0039] It should be understood that the examples and implementation modes described herein are for illustrative purposes only and are not intended to limit the present invention. Those skilled in the art may make various modifications or changes based on the examples and implementation modes. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A freezing box with cold storage function, characterized in that: It comprises a base (1), a cover plate (2), a box cover (3) and a cryopreservation tube (4); A plurality of holes (101) are spaced apart in the base (1), and a cavity (102) is provided inside the base (1) and outside the plurality of holes (101); The cover plate (2) is provided with a plurality of through holes (201) at intervals, and each of the through holes (201) matches each of the hole positions (101) in a one-to-one correspondence; The cover plate (2) is mounted on the top of the base (1) and is closed with the cavity (102) to form a hollow chamber (5), wherein a refrigerant is arranged in the hollow chamber (5); The cryotube (4) for collecting samples passes through the through hole (201) and is placed in the hole (101); The box cover (3) is arranged on the base (1).

2. The freezing box with cold storage function as claimed in claim 1, characterized in that: The base (1) is a box structure without a top cover, the cover plate (2) is a horizontal plate structure, and the cover plate (2) is provided with flange edges (202) along the four sides, and the flange edges (202) are matched with the mouth of the base (1).

3. The freezing box with cold storage function according to claim 1, characterized in that: The plurality of hole positions (101) are evenly arranged in the base (1) and are all in the shape of a cylinder without a cap. The mouth of each hole position (101) is flush with the mouth of the base (1). The plurality of through holes (201) are evenly arranged on the cover plate (2). The aperture of the through hole (201) is consistent with the aperture of the hole position (101), and the through hole (201) fits in contact with the mouth of the hole position (101).

4. The freezing box with cold storage function according to claim 1, characterized in that: The cryogenic tube (4) is a sealed sample tube, a tube plug (401) is installed at the tube mouth, the cryogenic tube (4) is inserted into the hole (101), and the tube plug (401) protrudes outward from the through hole (201).

5. The freezing box with cold storage function as claimed in claim 1, characterized in that: The box cover (3) is a box structure without a bottom cover, and is matched with the base (1) for cover assembly. The box body depth of the box cover (3) is greater than the box body depth of the base (1), and the base (1) can be covered therein.

6. The freezing box with cold storage function as claimed in claim 1, characterized in that: There are various types of the coolant.

Citation Information

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