Production device for natural collagen cross-linked gel loaded with L-polylactic acid microspheres

Abstract

The utility model relates to the technical field of cross-linked gel production devices, in particular to a natural collagen cross-linked gel production device loaded with L-polylactic acid microspheres. When discharging is needed, the lifting driving part is controlled to drive the movable driving box to move downwards, the stirring shaft is driven to move downwards, the lower portion of the scraping stirring blade is tightly attached to the bottom of the tank body, the discharging valve is controlled to be opened, and when the stirring shaft rotates, on one hand, materials are continuously guided downwards through the spiral stirring blade; on the other hand, the materials are scraped to the center through the scraping and stirring blades, enter the discharging opening through the avoiding grooves and flow out of the discharging opening, and by means of the structure, the phenomenon that gel products are hung on the wall can be greatly reduced, and the discharging efficiency is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of cross-linked gel production devices, in particular to a natural collagen cross-linked gel production device carrying L-polylactic acid microspheres. Background Art

[0002] L-polylactic acid (PLA) as a filler material is usually made into microspheres. It has been proven that its size, shape, and smoothness have a great influence on tissue reaction and can determine the degree of reaction. L-PLA microspheres with smooth surface and regular spherical shape can minimize the occurrence of inflammation; the smoother the L-PLA microspheres, the more conducive to subcutaneous injection. The smoother L-PLA microspheres can not only stimulate the fibroblasts under the wrinkles to wrap one by one, but also reduce the occurrence of foreign body reactions.

[0003] In order to improve the dispersibility of L-polylactic acid microspheres, a common preparation method is to blend L-polylactic acid microspheres with natural collagen gel, stir, and form a cross-linked gel. When preparing cross-linked gel in existing conventional stirring tanks, there are problems such as easy adhesion of materials to the wall and poor discharge. Utility Model Content

[0004] The technical problem to be solved by the utility model is to provide a natural collagen cross-linked gel production device carrying L-polylactic acid microspheres, so as to solve the problems of easy wall adhesion and poor material discharge in the existing production device.

[0005] In order to solve the above technical problems, the technical solution adopted by the utility model is:

[0006] A production device for natural collagen cross-linked gel loaded with L-polylactic acid microspheres, comprising:

[0007] frame;

[0008] A tank body, the tank body is connected to the frame, the tank body is in the shape of a rotating body with the axial direction in the vertical direction, the middle section of the tank body is a cylindrical section, the lower section of the tank body is a conical section, the lower end of the conical section is provided with a discharge port; the upper part of the tank body is provided with a feed port;

[0009] A discharge valve, the discharge valve being connected to the discharge port;

[0010] A movable driving box, the movable driving box is movably connected to the frame in a vertical direction, and the movable driving box is located above the tank body;

[0011] A lifting drive member, the lifting drive member is connected between the frame and the movable drive box, and is used to drive the movable drive box to move;

[0012] A stirring shaft, the upper end of which is rotatably connected to a movable driving box, and the stirring shaft is coaxially disposed in the tank body;

[0013] A spiral stirring blade, wherein the spiral stirring blade is connected to the middle portion of the stirring shaft;

[0014] A scraper stirring blade, wherein the scraper stirring blade is connected to the lower part of the stirring shaft, the lower part of the scraper stirring blade is a structure matching the inner wall of the conical section, and the scraper stirring blade is provided with an avoidance groove relative to the discharge port;

[0015] In the first state, the stirring shaft moves upward under the drive of the lifting drive member, so that the scraping stirring blades are separated from the bottom of the conical section of the tank body;

[0016] In the second state, the stirring shaft moves upward under the drive of the lifting drive member, so that the scraping stirring blades abut against the bottom of the conical section of the tank body.

[0017] Furthermore, in the above-mentioned natural collagen cross-linked gel production device structure loaded with L-polylactic acid microspheres, the lifting drive component is a telescopic cylinder, the cylinder body of the telescopic cylinder is connected to the frame, and the piston rod of the telescopic cylinder is connected to the movable drive box.

[0018] Furthermore, in the above-mentioned natural collagen cross-linked gel production device structure loaded with L-polylactic acid microspheres, the movable driving box comprises:

[0019] Box;

[0020] A transmission shaft, the axial direction of the transmission shaft is horizontal, and the transmission shaft is rotatably connected to the box body;

[0021] A motor, the motor is connected to the box, and the motor is drivingly connected to the transmission shaft;

[0022] A first bevel gear, wherein the first bevel gear is coaxially sleeved on the transmission shaft;

[0023] The second bevel gear is coaxially sleeved on the upper end of the stirring shaft, and the second bevel gear is meshed with the first bevel gear.

[0024] Furthermore, in the above-mentioned natural collagen cross-linked gel production device structure loaded with L-polylactic acid microspheres, the telescopic cylinder is a pneumatic cylinder, a hydraulic cylinder or an electric cylinder.

[0025] Furthermore, in the above-mentioned natural collagen cross-linked gel production device structure loaded with L-polylactic acid microspheres, the frame is provided with a vertical guide rail, and the movable driving box is slidably connected to the guide rail.

[0026] The beneficial effects of the utility model are as follows: first, natural collagen and trehalose are put into the tank body through the feed inlet, the lifting drive member is controlled to drive the movable drive box to move upward, drive the stirring shaft to move upward, adjust to the first state, make the scraping stirring blade separate from the bottom of the tank body, drive the stirring shaft to rotate through the movable drive box, make the spiral stirring blade continuously guide the material downward, and at the same time, the material is evenly stirred by the rotation of the scraping stirring blade to form a gel, and then L-polylactic acid microspheres are put into the box feed inlet, continue to control the rotation of the stirring shaft, make the L-polylactic acid microspheres and the gel evenly mixed, and then control the lifting drive member to drive the movable drive box to move downward, drive the stirring shaft to move downward, make the lower part of the scraping stirring blade close to the bottom of the tank body, control the discharge valve to open, so that when the stirring shaft rotates, on the one hand, the spiral stirring blade continuously guides the material downward, and on the other hand, the scraping stirring blade is used to scrape the material to the center through the avoidance groove into the discharge port and flow out from the discharge port. Through the above structure, the gel product wall hanging can be greatly reduced and the discharge efficiency can be improved. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 This is a schematic structural diagram of a device for producing a natural collagen cross-linked gel loaded with L-polylactic acid microspheres according to a specific embodiment of the utility model;

[0028] Description of labels:

[0029] 1. Frame; 11. Guide rail;

[0030] 2. Tank body; 21. Cylindrical section; 22. Conical section; 23. Feed inlet; 24. Discharge outlet;

[0031] 3. Discharge valve;

[0032] 4. Movable driving box; 41. Box body; 42. Transmission shaft; 43. First bevel gear; 44. Second bevel gear; 45. Motor;

[0033] 5. Lifting drive parts;

[0034] 6. Stirring shaft;

[0035] 7. Spiral stirring blade;

[0036] 8. Scraping and stirring blades; 81. Avoidance groove. DETAILED DESCRIPTION

[0037] In order to explain the technical content, achieved objectives and effects of the present invention in detail, the following is an explanation in conjunction with the implementation modes and the accompanying drawings.

[0038] Please refer to Figure 1 The specific embodiment of the utility model relates to a natural collagen cross-linked gel production device loaded with L-polylactic acid microspheres, comprising:

[0039] Rack 1;

[0040] A tank body 2, the tank body 2 is connected to the frame 1, the tank body 2 is in the shape of a rotating body with its axis in the vertical direction, the middle section of the tank body 2 is a cylindrical section 21, the lower section of the tank body 2 is a conical section 22, and a discharge port 24 is provided at the lower end of the conical section 22; a feed port 23 is provided at the upper portion of the tank body 2;

[0041] A discharge valve 3, wherein the discharge valve 3 is connected to the discharge port 24;

[0042] A movable driving box 4, wherein the movable driving box 4 is movably connected to the frame 1 in a vertical direction, and the movable driving box 4 is located above the tank body 2;

[0043] A lifting drive member 5, wherein the lifting drive member 5 is connected between the frame 1 and the movable drive box 4, and is used to drive the movable drive box 4 to move;

[0044] A stirring shaft 6, the upper end of which is rotatably connected to the movable driving box 4, and the stirring shaft 6 is coaxially disposed in the tank body 2;

[0045] A spiral stirring blade 7, wherein the spiral stirring blade 7 is connected to the middle portion of the stirring shaft 6;

[0046] A scraper stirring blade 8, wherein the scraper stirring blade 8 is connected to the lower part of the stirring shaft 6, the lower part of the scraper stirring blade 8 is a structure matching the inner wall of the conical section 22, and the scraper stirring blade 8 is provided with an avoidance groove 81 at a position relative to the discharge port 24;

[0047] In the first state, the stirring shaft 6 moves upward under the drive of the lifting drive member 5, so that the scraping stirring blade 8 is separated from the bottom of the conical section 22 of the tank body 2;

[0048] In the second state, the stirring shaft 6 moves upward under the drive of the lifting drive member 5 , so that the scraping stirring blade 8 abuts against the bottom of the conical section 22 of the tank body 2 .

[0049] In the above implementation mode, natural collagen and trehalose are first put into the tank body 2 through the feed port 23, and the lifting drive member 5 is controlled to drive the movable drive box 4 to move upward, drive the stirring shaft 6 to move upward, and adjust to the first state, so that the scraping stirring blade 8 is separated from the bottom of the tank body 2, and the stirring shaft 6 is driven to rotate by the movable drive box 4, so that the spiral stirring blade 7 continuously guides the material downward, and at the same time, the material is evenly stirred by the rotation of the scraping stirring blade 8 to form a gel, and then L-polylactic acid microspheres are put into the box feed port 23, and the stirring shaft 6 is continuously controlled to rotate. The L-polylactic acid microspheres are mixed evenly with the gel, and then the lifting drive member 5 is controlled to drive the movable drive box 4 to move downward, and the stirring shaft 6 is driven to move downward, so that the lower part of the scraping stirring blade 8 is close to the bottom of the tank body 2, and the discharge valve 3 is controlled to open. When the stirring shaft 6 rotates, on the one hand, the material is continuously guided downward by the spiral stirring blade 7, and on the other hand, the scraping stirring blade 8 is used to scrape the material to the center through the avoidance groove 81 into the discharge port 24, and flows out from the discharge port 24. Through the above structure, the gel product can be greatly reduced from hanging on the wall and the discharge efficiency can be improved.

[0050] As a preferred embodiment, the lifting drive member 5 is a telescopic cylinder, a cylinder body of the telescopic cylinder is connected to the frame 1 , and a piston rod of the telescopic cylinder is connected to the movable drive box 4 .

[0051] As a preferred embodiment, the movable driving box 4 includes:

[0052] Box 41;

[0053] A transmission shaft 42, wherein the axial direction of the transmission shaft 42 is horizontal, and the transmission shaft 42 is rotatably connected to the box body 41;

[0054] A motor 45, wherein the motor 45 is connected to the box body 41, and the motor 45 is in driving connection with the transmission shaft 42;

[0055] A first bevel gear 43, wherein the first bevel gear 43 is coaxially sleeved on the transmission shaft 42;

[0056] The second bevel gear 44 is coaxially sleeved on the upper end of the stirring shaft 6, and the second bevel gear 44 is meshed with the first bevel gear 43. By utilizing the steering transmission of the first bevel gear 43 and the second bevel gear 44, the motor 45 can be arranged on the side of the movable transmission box, making the mechanical structure distribution more reasonable.

[0057] As a preferred embodiment, the telescopic cylinder is a pneumatic cylinder, a hydraulic cylinder or an electric cylinder.

[0058] As a preferred embodiment, the frame 1 is provided with a vertical guide rail 11, and the movable drive box 4 is slidably connected to the guide rail 11. The guide rail 11 limits the moving direction of the movable drive box 4, thereby improving the stability of the mechanism.

[0059] The above description is only an embodiment of the present invention, and does not limit the patent scope of the present invention. Any equivalent transformations made using the contents of the specification and drawings of the present invention, or directly or indirectly applied in the relevant technical field, are also included in the patent protection scope of the present invention.

Claims

1. A device for producing a natural collagen cross-linked gel loaded with L-polylactic acid microspheres, characterized in that: include: frame; A tank body, the tank body is connected to the frame, the tank body is in the shape of a rotating body with the axial direction in the vertical direction, the middle section of the tank body is a cylindrical section, the lower section of the tank body is a conical section, the lower end of the conical section is provided with a discharge port; the upper part of the tank body is provided with a feed port; A discharge valve, the discharge valve being connected to the discharge port; A movable driving box, the movable driving box is movably connected to the frame in a vertical direction, and the movable driving box is located above the tank body; A lifting drive member, the lifting drive member is connected between the frame and the movable drive box, and is used to drive the movable drive box to move; A stirring shaft, the upper end of which is rotatably connected to a movable driving box, and the stirring shaft is coaxially disposed in the tank body; A spiral stirring blade, wherein the spiral stirring blade is connected to the middle portion of the stirring shaft; A scraper stirring blade, wherein the scraper stirring blade is connected to the lower part of the stirring shaft, the lower part of the scraper stirring blade is a structure matching the inner wall of the conical section, and the scraper stirring blade is provided with an avoidance groove relative to the discharge port; In the first state, the stirring shaft moves upward under the drive of the lifting drive member, so that the scraping stirring blades are separated from the bottom of the conical section of the tank body; In the second state, the stirring shaft moves upward under the drive of the lifting drive member, so that the scraping stirring blades abut against the bottom of the conical section of the tank body.

2. The natural collagen cross-linked gel production device loaded with L-polylactic acid microspheres according to claim 1, characterized in that: The lifting drive member is a telescopic cylinder, a cylinder body of the telescopic cylinder is connected to a frame, and a piston rod of the telescopic cylinder is connected to a movable drive box.

3. The natural collagen cross-linked gel production device loaded with L-polylactic acid microspheres according to claim 1, characterized in that: The movable drive box comprises: Box; A transmission shaft, the axial direction of the transmission shaft is horizontal, and the transmission shaft is rotatably connected to the box body; A motor, the motor is connected to the box, and the motor is drivingly connected to the transmission shaft; A first bevel gear, wherein the first bevel gear is coaxially sleeved on the transmission shaft; The second bevel gear is coaxially sleeved on the upper end of the stirring shaft, and the second bevel gear is meshed with the first bevel gear.

4. The natural collagen cross-linked gel production device loaded with L-polylactic acid microspheres according to claim 2, characterized in that: The telescopic cylinder is a pneumatic cylinder, a hydraulic cylinder or an electric cylinder.

5. The natural collagen cross-linked gel production device loaded with L-polylactic acid microspheres according to claim 2, characterized in that: The frame is provided with a vertical guide rail, and the movable driving box is slidably connected to the guide rail.

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