Constant temperature device for chromatographic column

Abstract

The utility model provides a constant temperature device for a chromatographic column, which comprises a constant temperature box body, constant temperature structures, a clamping structure, a chromatographic column body and a pushing structure, the two sides of the inner wall of the constant temperature box body are respectively provided with a group of constant temperature structures, each constant temperature structure comprises a heating wire and a single chip microcomputer, and the chromatographic column body is arranged in the constant temperature box body. The outer surface of the chromatographic column body is sleeved with two clamping structures, and one side of each clamping structure is provided with a pushing structure. According to the device, the clamping structures are arranged, the clamping plates are extruded, the telescopic rods are extruded by the clamping plates, the springs are extruded while the telescopic rods enter the sleeves, the springs contract to generate elastic force, an operator places a chromatographic column body between the two sets of clamping plates in the two sets of mounting supports, the operator releases the clamping plates, and under the elastic force action of the springs, the chromatographic column body is clamped by the clamping plates. The spring resets, the telescopic rod is pushed to reset, the clamping plate is pushed to clamp the chromatographic column body, and the situation that the chromatographic column falls off and is damaged due to loosening of the buckle is effectively avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of chromatographic column constant temperature, in particular to a chromatographic column constant temperature device. Background Art

[0002] The chromatographic column is composed of a column tube, a pressure cap, a ferrule (sealing ring), a sieve plate (filter disc), a joint, screws, etc. The chromatographic column can be divided into two categories: a packed column and an open tube column. Most of them are made of metal or glass. There are straight tubes, coils, U-shaped tubes and other shapes. Liquid chromatography usually uses packed columns. The separation effect of the chromatographic column depends on the selected stationary phase, as well as the preparation and operating conditions of the chromatographic column. The liquid chromatography column thermostat - column thermostat, is a core module component of the high performance liquid chromatograph, responsible for providing an ideal constant temperature environment for the adsorption-desorption distribution process of the liquid chromatography column;

[0003] In order to place the chromatographic column, the thermostat usually uses clips to lock the chromatographic column. The clips will become loose after locking the chromatographic column for multiple times, which can easily cause the chromatographic column to fall off and cause damage to the chromatographic column. The chromatographic column needs to be placed on an external rack for adjustment before being placed in the thermostat. The chromatographic column needs to be moved when placed in the thermostat. If the shaking amplitude is too large during the movement, the chromatographic column will vibrate. However, if the chromatographic column encounters vibration during the adsorption and analysis process, the detection accuracy will be reduced. Utility Model Content

[0004] In order to solve the above technical problems, the utility model provides a constant temperature device for a chromatographic column.

[0005] The utility model provides a constant temperature device for a chromatographic column, comprising: a constant temperature box, a constant temperature structure, a clamping structure, a chromatographic column body and a pushing structure. A group of constant temperature structures are arranged on both sides of the inner wall of the constant temperature box, the constant temperature structure comprises a heating wire and a single-chip computer, a chromatographic column body is arranged inside the constant temperature box, and two groups of clamping structures are arranged on the outer surface of the chromatographic column body, the clamping structure comprises a mounting bracket, a sleeve, a spring and a telescopic rod, and a group of pushing structures are arranged on one side of each group of clamping structures, and the pushing structure comprises a servo motor, a gear and a rack.

[0006] Preferably, the side walls of the thermostatic box entrance and exit are hinged with a sealed door, a plurality of groups of threaded holes are opened on both sides of the inner wall of the thermostatic box, temperature sensors are fixedly connected to both sides of the inner wall of the thermostatic box, two groups of cavities are opened on the inner wall of the thermostatic box, two groups of through holes are opened on the side walls of the two groups of cavities, the through holes are interconnected with the interior of the thermostatic box, a cavity is also opened at the bottom of the thermostatic box, two groups of through holes are opened on the side walls of the cavity at the bottom of the thermostatic box, the through holes are interconnected with the interior of the thermostatic box.

[0007] Preferably, several groups of fixing clamps are engaged with the outer surface of the heating wire, and each group of fixing clamps is provided with a threaded hole on the side surface of the fixing clamps. Bolts are arranged inside the threaded holes on the side surfaces of the fixing clamps. One end of the bolt extends to the inside of the threaded holes on both sides of the inner wall of the constant temperature box body. The lower end of the heating wire passes through the through hole at the bottom of the constant temperature box body and extends to the inside of the bottom cavity of the constant temperature box body. A single-chip microcomputer is fixedly connected to the inner wall of the bottom cavity of the constant temperature box body, the lower end of the heating wire is electrically connected to the single-chip microcomputer, and the single-chip microcomputer is electrically connected to the temperature sensor.

[0008] Preferably, a group of sleeves are fixedly connected to the inner walls on both sides of the mounting bracket, and a spring is arranged inside each group of sleeves. One end of the spring is fixedly connected to the inner wall of the sleeve, and the other end of the spring is provided with a telescopic rod. One end of the telescopic rod is fixedly connected to one end of the spring, and the telescopic rod extends away from one end of the spring to the outer surface of the sleeve.

[0009] Preferably, the end of the telescopic rod away from the spring is fixedly connected to a clamping plate, and the clamping plate at the end of the telescopic rod away from the spring inside the inner wall sleeve on both sides of the mounting bracket in each set of clamping structures is attached to the outer surface of the chromatographic column.

[0010] Preferably, the bottom of the servo motor is fixedly connected to the bottom of the inner wall cavity of the constant temperature box, and the power output end of the servo motor is fixedly connected to a gear, and a rack is meshed under the gear. The lower surface of the rack is slidably arranged on the bottom of the two groups of cavities on the inner wall of the constant temperature box, and one end of the rack extends through the two groups of cavity side wall through holes of the constant temperature box to the inside of the constant temperature box. One end of the rack in the two groups of pushing structures extends to the inside of the constant temperature box and is fixedly connected to the outer surface of the mounting bracket in the two groups of clamping structures.

[0011] Compared with the related art, the constant temperature device for the chromatographic column provided by the utility model has the following beneficial effects:

[0012] By providing a clamping structure, squeezing the clamping plate, the clamping plate squeezes the telescopic rod, the telescopic rod enters the inside of the sleeve and squeezes the spring at the same time, the spring contracts to generate elastic force, the operator places the chromatographic column body between the two groups of clamping plates inside the two groups of mounting brackets, the operator releases the clamping plate, under the elastic force of the spring, the spring resets, pushes the telescopic rod to reset, and pushes the clamping plate to clamp the chromatographic column body, effectively avoiding the chromatographic column from falling off and being damaged due to loose buckles.

[0013] By providing a pushing structure, the servo motor is started, and the power input end of the servo motor rotates to drive the gear to rotate. When the gear rotates, it meshes with the movement of the rack below. When the rack moves, it slides along the bottom of the two groups of cavities inside the constant temperature box, and gradually passes through the through holes on the side walls of the two groups of cavities to extend to the inside of the constant temperature box, so that the clamping structure extends to the outer surface of the constant temperature box to clamp the chromatographic column. After the observation object is placed inside the chromatographic column, the power output end of the servo motor is controlled to reverse, so that the rack slides back to the cavity inside the constant temperature box, driving the clamped chromatographic column to enter the inside of the constant temperature box, effectively avoiding the vibration of the chromatographic column and effectively improving the detection accuracy. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 A schematic structural diagram of a preferred embodiment of a thermostatic device for a chromatographic column provided by the utility model;

[0015] Figure 2 It is a schematic diagram of the exploded structure of the interior of the constant temperature box of the utility model;

[0016] Figure 3 It is a schematic diagram of the exploded structure of the clamping structure of the utility model;

[0017] Figure 4 For the utility model Figure 2 Schematic diagram of the enlarged structure at point A in the middle.

[0018] Numbers in the figure: 1. Constant temperature box; 2. Constant temperature structure; 3. Heating wire; 4. Single chip microcomputer; 5. Chromatographic column; 6. Clamping structure; 7. Mounting bracket; 8. Sleeve; 9. Spring; 10. Telescopic rod; 11. Pushing structure; 12. Servo motor; 13. Gear; 14. Rack; 15. Sealing door; 16. Temperature sensor; 17. Fixing ring; 18. Bolt; 19. Clamping plate. DETAILED DESCRIPTION

[0019] The utility model is further described below in conjunction with the accompanying drawings and implementation modes.

[0020] Please refer to Figure 1 , Figure 2 , Figure 3 and Figure 4 ,in, Figure 1 A schematic structural diagram of a preferred embodiment of a thermostatic device for a chromatographic column provided by the utility model; Figure 2 It is a schematic diagram of the exploded structure of the interior of the constant temperature box of the utility model; Figure 3 It is a schematic diagram of the exploded structure of the clamping structure of the utility model; Figure 4 For the utility model Figure 2The enlarged structural diagram at A in the middle includes: a constant temperature box 1, a constant temperature structure 2, a clamping structure 6, a column and a pushing structure 11. A set of constant temperature structures 2 are arranged on both sides of the inner wall of the constant temperature box 1. The constant temperature structure 2 includes a heating wire 3 and a single-chip computer 4. A chromatographic column 5 is arranged inside the constant temperature box 1. Two sets of clamping structures 6 are sleeved on the outer surface of the chromatographic column 5. The clamping structure 6 is convenient for clamping the chromatographic column 5. The clamping structure 6 includes a mounting bracket 7, a sleeve 8, a spring 9 and a telescopic rod 10. A set of pushing structures 11 is arranged on one side of each set of clamping structures 6. The pushing structure 11 includes a servo motor 12, a gear 13 and a rack 14. The pushing structure 11 is convenient for pushing the clamping structure 6 in and out of the constant temperature box 1.

[0021] In the specific implementation process, Figure 1 , Figure 2 , Figure 3 and Figure 4 As shown, a sealing door 15 is hinged on the side wall of the entrance and exit of the constant temperature box 1, and the sealing door 15 is convenient for sealing the constant temperature box 1. Several groups of threaded holes are opened on both sides of the inner wall of the constant temperature box 1, and temperature sensors 16 are fixedly connected on both sides of the inner wall of the constant temperature box 1. The temperature sensor 16 is convenient for measuring the temperature. Two groups of cavities are opened on the inner wall of the constant temperature box 1, and two groups of through holes are opened on the side walls of the two groups of cavities. The through holes are interconnected with the interior of the constant temperature box 1. The bottom of the constant temperature box 1 is also opened with a cavity, and the side walls of the bottom cavity of the constant temperature box 1 are opened with two groups of through holes, and the through holes are interconnected with the interior of the constant temperature box 1.

[0022] Among them, the outer surface of the heating wire 3 is clamped with a plurality of groups of fixing clamps 17, and the side surface of each group of fixing clamps 17 is provided with a threaded hole, and a bolt 18 is arranged inside the threaded hole on the side surface of the fixing clamp 17. One end of the bolt 18 extends to the inside of the threaded holes on both sides of the inner wall of the constant temperature box 1. The fixing clamp 17 and the bolt 18 are convenient for fixing the heating wire 3 to the inner wall of the constant temperature box. The lower end of the heating wire 3 passes through the bottom through hole in the constant temperature box 1 and extends to the bottom cavity inside the constant temperature box 1. The inner wall of the bottom cavity in the constant temperature box 1 is fixedly connected with a single piece Machine 4, the lower end of the heating wire 3 is electrically connected to the single-chip microcomputer 4, the single-chip microcomputer 4 is electrically connected to the temperature sensor 16, the single-chip microcomputer 4 and the heating wire 3 are connected to an external power supply, after the operator sets a suitable temperature range for the single-chip microcomputer 4, the single-chip microcomputer 4 controls the heating wire 3 to heat, when the temperature sensor 16 measures that the internal temperature of the constant temperature box 1 is higher than the set temperature, the heating is stopped, if the temperature sensor 16 measures that the internal temperature of the constant temperature box 1 is lower than the set temperature, the heating is started, and the constant temperature range inside the constant temperature box 1 is always maintained.

[0023] Among them, the inner walls on both sides of the mounting bracket 7 are respectively fixedly connected with a group of sleeves 8, each group of sleeves 8 is provided with a spring 9, one end of the spring 9 is fixedly connected to the inner wall of the sleeve 8, and the other end of the spring 9 is provided with a telescopic rod 10, one end of the telescopic rod 10 is fixedly connected to one end of the spring 9, and the telescopic rod 10 extends away from one end of the spring 9 to the outer surface of the sleeve 8, and the telescopic rod 10 is fixedly connected to one end of the spring 9 to the outer surface of the sleeve 8. The clamping plate 19 is fixedly connected to the inner wall sleeve 8 on both sides of the mounting bracket 7 in each group of clamping structures 6. The telescopic rod 10 is away from the spring 9. The clamping plate 19 at one end of the spring 9 is attached to the outer surface of the chromatographic column body 5, squeezing the clamping plate 19, and the clamping plate 19 squeezes the telescopic rod 10. The telescopic rod 10 enters the inside of the sleeve 8 and squeezes the spring 9. The spring 9 contracts to generate elastic force, and the operator places the chromatographic column body 5 between the two groups of clamping plates 19 inside the two groups of mounting brackets 7. The operator releases the clamping plate 19. Under the elastic force of the spring 9, the spring 9 is reset, pushing the telescopic rod 10 to reset, and pushing the clamping plate 19 to clamp the chromatographic column body 5.

[0024] Among them, the bottom of the servo motor 12 is fixedly connected to the bottom of the inner wall cavity of the constant temperature box 1, and the power output end of the servo motor 12 is fixedly connected to a gear 13, and a rack 14 is meshed below the gear 13. The lower surface of the rack 14 is slidably arranged at the bottom of the two groups of cavities on the inner wall of the constant temperature box 1. One end of the rack 14 passes through the through holes on the side walls of the two groups of cavities of the constant temperature box 1 and extends to the inside of the constant temperature box 1. The racks 14 in the two groups of pushing structures 11 extend to the inside of the constant temperature box 1. One end is fixedly connected to the outer surface of the mounting bracket 7 in the two groups of clamping structures 6, and the servo motor 12 is electrically connected to the external power supply. Connect and start the servo motor 12. The rotation of the power output end of the servo motor 12 drives the gear 13 to rotate. When the gear 13 rotates, it engages the movement of the rack 14 below. When the rack 14 moves, it slides along the bottom of the two groups of cavities inside the constant temperature box 1, and gradually passes through the through holes on the side walls of the two groups of cavities to extend to the inside of the constant temperature box 1. The mounting bracket 7 in the clamping structure 6 is pushed to the outside of the constant temperature box 1, and the power output end of the servo motor 12 is controlled to reverse, so that the rack 14 slides back to the internal cavity of the constant temperature box 1, driving the clamped chromatographic column to enter the inside of the constant temperature box 1.

[0025] The working principle provided by the utility model is as follows: when using the constant temperature box 1, the operator first opens the sealing door 15, the operator starts the servo motor 12, the power input end of the servo motor 12 rotates to drive the gear 13 to rotate, and when the gear 13 rotates, it engages with the lower rack 14 to move, and when the rack 14 moves, it slides along the bottom of the two groups of cavities inside the constant temperature box 1, and gradually passes through the two groups of cavity side wall through holes to extend to the inside of the constant temperature box 1, and pushes the mounting bracket 7 in the clamping structure 6 to the outside of the constant temperature box 1, the operator squeezes the clamping plate 19, the clamping plate 19 squeezes the telescopic rod 10, and the telescopic rod 10 enters the inside of the sleeve 8 and squeezes the spring 9, and the spring 9 contracts to generate elastic force, the operator places the chromatographic column body 5 between the two groups of clamping plates 19 inside the two groups of mounting brackets 7, and the operator releases the clamping plate 19, Under the elastic force of spring 9, spring 9 is reset, pushing telescopic rod 10 to reset, pushing clamping plate 19 to clamp chromatographic column body 5, and after placing the observation object inside the chromatographic column, the operator controls the power output end of servo motor 12 to reverse, so that rack 14 slides back to the internal cavity of constant temperature box 1, driving the clamped chromatographic column into the constant temperature box 1, the operator closes the sealing door 15, connects single chip microcomputer 4 and heating wire 3 to external power supply, after the operator sets a suitable temperature range for single chip microcomputer 4, single chip microcomputer 4 controls heating wire 3 to heat, when temperature sensor 16 measures that the internal temperature of constant temperature box 1 is higher than the set temperature, heating is stopped, if temperature sensor 16 measures that the internal temperature of constant temperature box 1 is lower than the set temperature, heating is started, and the constant temperature range inside constant temperature box 1 is always maintained.

[0026] The circuits and controls involved in the present invention are all prior art and will not be described in detail here.

[0027] The above description is only an embodiment of the present invention, and does not limit the patent scope of the present invention. Any equivalent structure or equivalent process transformation made by using the contents of the specification and drawings of the present invention, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the present invention.

Claims

1. A constant temperature device for a chromatographic column, comprising: A constant temperature box (1), a constant temperature structure (2), a clamping structure (6), a chromatographic column body (5) and a pushing structure (11), characterized in that a group of constant temperature structures (2) are arranged on both sides of the inner wall of the constant temperature box (1), the constant temperature structure (2) comprises a heating wire (3) and a single chip computer (4), a chromatographic column body (5) is arranged inside the constant temperature box (1), and two groups of clamping structures (6) are sleeved on the outer surface of the chromatographic column body (5), the clamping structure (6) comprises a mounting bracket (7), a sleeve (8), a spring (9) and a telescopic rod (10), and a group of pushing structures (11) are arranged on one side of each group of clamping structures (6), and the pushing structure (11) comprises a servo motor (12), a gear (13) and a rack (14).

2. The constant temperature device for a chromatographic column according to claim 1, characterized in that: The entrance and exit side walls of the thermostatic box (1) are hingedly connected with a sealing door (15); a plurality of groups of threaded holes are provided on both sides of the inner wall of the thermostatic box (1); temperature sensors (16) are fixedly connected to both sides of the inner wall of the thermostatic box (1); two groups of cavities are provided on the inner wall of the thermostatic box (1); two groups of through holes are provided on the side walls of the two groups of cavities; the through holes are interconnected with the interior of the thermostatic box (1); a cavity is also provided on the bottom of the thermostatic box (1); two groups of through holes are provided on the side walls of the cavity at the bottom of the thermostatic box (1); the through holes are interconnected with the interior of the thermostatic box (1).

3. The constant temperature device for a chromatographic column according to claim 1, characterized in that: The outer surface of the heating wire (3) is engaged with a plurality of groups of fixing clamps (17), and a threaded hole is formed on the side surface of each group of fixing clamps (17). Bolts (18) are arranged inside the threaded holes on the side surfaces of the fixing clamps (17), and one end of the bolts (18) extends to the inside of the threaded holes on both sides of the inner wall of the constant temperature box (1). The lower end of the heating wire (3) passes through the through hole at the bottom of the constant temperature box (1) and extends to the inside of the bottom cavity of the constant temperature box (1). A single-chip computer (4) is fixedly connected to the inner wall of the bottom cavity of the constant temperature box (1), and the lower end of the heating wire (3) is electrically connected to the single-chip computer (4), and the single-chip computer (4) is electrically connected to the temperature sensor (16).

4. The constant temperature device for a chromatographic column according to claim 1, characterized in that: A group of sleeves (8) are fixedly connected to the inner walls of both sides of the mounting bracket (7), each group of sleeves (8) is provided with a spring (9) inside, one end of the spring (9) is fixedly connected to the inner wall of the sleeve (8), and the other end of the spring (9) is provided with a telescopic rod (10), one end of the telescopic rod (10) is fixedly connected to one end of the spring (9), and the telescopic rod (10) extends away from one end of the spring (9) to the outer surface of the sleeve (8).

5. The constant temperature device for a chromatographic column according to claim 1, characterized in that: The end of the telescopic rod (10) away from the spring (9) is fixedly connected to a clamping plate (19), and the clamping plate (19) at the end of the telescopic rod (10) away from the spring (9) is attached to the outer surface of the chromatographic column body (5) in each set of clamping structures (6) and the inner wall sleeves (8) on both sides of the mounting bracket (7).

6. The constant temperature device for a chromatographic column according to claim 1, characterized in that: The bottom of the servo motor (12) is fixedly connected to the bottom of the inner cavity of the thermostatic box (1); the power output end of the servo motor (12) is fixedly connected to a gear (13); a rack (14) is meshed below the gear (13); the lower surface of the rack (14) is slidably arranged on the bottom of two groups of cavities on the inner wall of the thermostatic box (1); one end of the rack (14) passes through the through holes on the side walls of the two groups of cavities of the thermostatic box (1) and extends to the interior of the thermostatic box (1); one end of the rack (14) in the two groups of pushing structures (11) extending to the interior of the thermostatic box (1) is fixedly connected to the outer surface of the mounting bracket (7) in the two groups of clamping structures (6).

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