Enzyme linked immunosorbent assay analyzer

By designing a combination of clamping mechanism and anti-fouling pallet in the enzyme-linked immunoassay device, the problems of poor spatial matching of the enzyme mark plate and difficulty in cleaning the detection chamber are solved, and stable clamping and convenient cleaning of the enzyme mark plate are achieved.

CN222299631UActive Publication Date: 2025-01-03JIANGXI JIANWEI BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202420876940.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-25
Publication Date
2025-01-03
Estimated Expiration
2034-04-25

AI Technical Summary

Technical Problem

The existing enzyme-linked immunoassays have poor spatial matching when placing small enzyme plates and the detection chamber is inconvenient to clean.

Method used

An enzyme-linked immunoassay device including a detection chamber, a pull-out end plate and a clamping mechanism is designed. The clamping mechanism consists of a limiting splint, a guide slider, a return spring, an anti-fouling pallet, etc., and is connected by a clamping mechanism. The enzyme label plate is fixed and positioned, and the anti-fouling pallet can be flexibly disassembled and assembled for easy cleaning.

Benefits of technology

It effectively reduces the oscillation of the enzyme label plate during the detection process, realizes adaptive clamping of the enzyme label plates of different sizes, and provides a convenient cleaning method.

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Abstract

The utility model discloses an enzyme linked immunosorbent assay analyzer, which belongs to the technical field of analyzers, and aims to solve the problems that in the prior art, a small enzyme label plate is placed in a detection bin, so that the space matching performance is poor, and the detection bin is inconvenient to clean, the enzyme linked immunosorbent assay analyzer comprises an analyzer body, and the detection bin is arranged at the front port of the analyzer body; a drawing end plate is fixed to the front end of the detection bin, a clamping mechanism is arranged in the detection bin and comprises a limiting clamping plate, a guide sliding block and a reset spring, the limiting clamping plate is slidably connected to the interior of the detection bin, and the guide sliding block is slidably connected to the interior of the drawing end plate; according to the utility model, through the arranged clamping mechanism, the limiting clamping plate can contract the clamping opening and clamp and fix the elisa plate under the action of resilience force of the reset spring, so that the trouble of oscillation caused by displacement of the elisa plate in the detection process can be reduced; due to the self-adaptive clamping effect of the limiting clamping plate, the ELISA plates with different sizes can be positioned and used.
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Description

Technical Field

[0001] The utility model belongs to the technical field of analyzers, and in particular relates to an enzyme-linked immunosorbent analyzer. Background Art

[0002] Enzyme-linked immunosorbent assay (ELISA) is a special instrument for enzyme-linked immunosorbent assay (ELISA). It can be simply divided into two categories: semi-automatic and fully automatic. However, its working principles are basically the same. Its core is a colorimeter, which uses colorimetry to analyze the content of antigens or antibodies.

[0003] At present, the placement of the ELISA plate needs to be stable to avoid contamination between reagents caused by vibration. However, the existing ELISA plate is directly placed in the detection chamber, and the ELISA plate has a movable space in the detection chamber. In addition, the ELISA plate is divided into different sizes, so there is a disadvantage of poor space matching when placing a smaller ELISA plate in the detection chamber. In addition, the detection chamber is in a groove shape as a whole, and the detection chamber and the analyzer housing are generally not easy to disassemble. In this way, it is difficult to properly clean the detection chamber after the detection liquid is spilled inside the detection chamber.

[0004] Therefore, an enzyme-linked immunosorbent analyzer is needed to solve the problems in the prior art that a smaller ELISA plate placed in a detection chamber has poor spatial matching and the detection chamber is inconvenient to clean. Utility Model Content

[0005] The purpose of the utility model is to provide an enzyme-linked immunosorbent assay instrument to solve the problems raised in the above-mentioned background technology.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: an enzyme-linked immunosorbent analyzer, comprising an analyzer body, a front port of the analyzer body is provided with a detection chamber, a pull-out end plate is fixed at the front end of the detection chamber, a clamping mechanism is provided inside the detection chamber, the clamping mechanism includes a limit clamping plate, a guide slider and a reset spring, the limit clamping plate is slidably connected to the inside of the detection chamber, the guide slider is slidably connected to the inside of the pull-out end plate, the reset spring is arranged inside the pull-out end plate, the lower port of the detection chamber is embedded with an anti-fouling support plate, and two assembly sliders are fixed to the lower end surface of the limit clamping plate.

[0007] It should be noted in the solution that one end of the guide slider is fixed to one end surface of the limiting clamp, a guide slot is provided inside the pull-out end plate, and the guide slider is slidably matched with the guide slot of the pull-out end plate.

[0008] It is further worth noting that a through sliding hole is formed through one side surface of the guide slider, a guide cross bar is fixed between the walls where the guide slide groove is located, and the through sliding hole of the guide slider is slidably sleeved on the surface of the guide cross bar.

[0009] It should be further explained that the return spring is sleeved on the surface of the guide cross bar, one end of the return spring is fixed to a side surface of the guide slider, and the other end of the return spring is fixed to the inner wall of the drawer end plate.

[0010] As a preferred implementation, a non-slip pad is fixed to one side surface of the limiting clamping plate, and a clamping opening is provided between the limiting clamping plate and the inner wall of the detection chamber.

[0011] As a preferred embodiment, an assembly groove is formed on the inner bottom wall of the anti-fouling support plate, and the assembly sliding block is slidably connected to the assembly groove of the anti-fouling support plate.

[0012] As a preferred embodiment, an anti-slip groove is provided on the inner wall of the analyzer body, an anti-slip buckle is slidably connected inside the anti-slip groove, and one end of the anti-slip buckle is fixed to the side of the detection chamber.

[0013] As a preferred implementation, a display panel is disposed on the upper portion of the analyzer body, and a control button is disposed on the upper portion of the analyzer body on one side of the display panel.

[0014] Compared with the prior art, the enzyme-linked immunosorbent assay (ELISA) provided by the present invention has at least the following beneficial effects:

[0015] ⑴ Through the clamping mechanism, the limit clamp can shrink the clamping mouth and clamp the ELISA plate under the action of the rebound force of the reset spring, which can reduce the trouble of displacement and oscillation of the ELISA plate during the detection process. The adaptive clamping effect of the limit clamp can also be used for positioning of ELISA plates of different sizes.

[0016] (2) By setting up the anti-fouling pallet and the assembly slider, the anti-fouling pallet can be removed from the inspection chamber during cleaning, and the anti-fouling pallet can be flexibly disassembled and assembled to provide conditions for convenient cleaning. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the technical solutions of the embodiments of the utility model, the drawings required for describing the embodiments are briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0018] Figure 1 This is a three-dimensional diagram of the overall structure of an enzyme-linked immunosorbent analyzer of the utility model;

[0019] Figure 2 This is a three-dimensional diagram of the detection chamber structure of an enzyme-linked immunosorbent analyzer of the utility model;

[0020] Figure 3 This is a three-dimensional diagram of the cross-sectional structure of a pull-out end plate of an enzyme-linked immunosorbent analyzer of the utility model;

[0021] Figure 4 The utility model is a three-dimensional diagram of a limit clamp structure of an enzyme-linked immunosorbent analyzer.

[0022] In the figure: 1. Analyzer body; 2. Display panel; 3. Detection chamber; 4. Anti-slip buckle; 5. Pull-out end plate; 6. Limiting clamp; 7. Guide slider; 8. Anti-slip gasket; 9. Through-slide hole; 10. Guide cross bar; 11. Reset spring; 12. Guide slide groove; 13. Assembly slider; 14. Anti-fouling support plate; 15. Assembly groove. DETAILED DESCRIPTION

[0023] The present invention will be further described below in conjunction with the embodiments.

[0024] See also Figure 1-4 The utility model provides an enzyme-linked immunosorbent analyzer, including an analyzer body 1, a detection chamber 3 is arranged at the front port of the analyzer body 1, a pull-out end plate 5 is fixed at the front end of the detection chamber 3, a clamping mechanism is arranged inside the detection chamber 3, the clamping mechanism includes a limit clamping plate 6, a guide slider 7 and a reset spring 11, the limit clamping plate 6 is slidably connected to the inside of the detection chamber 3, the guide slider 7 is slidably connected to the inside of the pull-out end plate 5, the reset spring 11 is arranged inside the pull-out end plate 5, an anti-fouling support plate 14 is embedded in the lower port of the detection chamber 3, and two assembly sliders 13 are fixed to the lower end surface of the limit clamping plate 6.

[0025] Further as Figure 1 , Figure 2 and Figure 3 As shown, it is worth explaining in detail that one end of the guide slider 7 is fixed on one end surface of the limiting clamp 6, and a guide groove 12 is opened inside the pull-out end plate 5, and the guide slider 7 is slidably matched with the guide groove 12 of the pull-out end plate 5.

[0026] Further as Figure 3 As shown, it is worth explaining in detail that a through sliding hole 9 is opened through the surface of one side of the guide slider 7, a guide cross bar 10 is fixed between the walls where the guide slide groove 12 is located, and the through sliding hole 9 of the guide slider 7 is slidably sleeved on the surface of the guide cross bar 10.

[0027] This solution has the following working process: before use, the detection chamber 3 is pulled out from the analyzer body 1, and then the limit clamp 6 is pushed backward, and then the ELISA plate is placed in the clamping opening between the limit clamp 6 and the inner wall of the detection chamber 3. Finally, the limit clamp 6 can shrink the clamping opening and clamp the ELISA plate under the rebound force of the reset spring 11, which can reduce the trouble of displacement and oscillation of the ELISA plate during the detection process. The adaptive clamping effect of the limit clamp 6 can also be used for positioning ELISA plates of different sizes.

[0028] According to the above working process, it can be known that the limiting clamp 6 can shrink the clamping mouth and clamp and fix the ELISA plate under the action of the rebound force of the reset spring 11, which can reduce the trouble of displacement and oscillation of the ELISA plate during the detection process. The adaptive clamping effect of the limiting clamp 6 can also be used for positioning ELISA plates of different sizes.

[0029] Further as Figure 1 , Figure 2 and Figure 4 As shown, it is worth explaining in detail that the return spring 11 is sleeved on the surface of the guide cross bar 10, one end of the return spring 11 is fixed to the side surface of the guide slider 7, and the other end of the return spring 11 is fixed to the inner wall of the pull-out end plate 5.

[0030] Further as Figure 4 As shown, it is worth to explain in detail that a non-slip pad 8 is fixed to one side surface of the limiting clamping plate 6 , and a clamping opening is arranged between the limiting clamping plate 6 and the inner wall of the detection chamber 3 .

[0031] Further as Figure 1 As shown, it is worth explaining in detail that an assembly groove 15 is provided on the inner bottom wall of the anti-fouling support plate 14, and the assembly slider 13 is slidably connected to the assembly groove 15 of the anti-fouling support plate 14. When the detection liquid in the well of the ELISA plate drops onto the anti-fouling support plate 14, contamination problems will occur. When cleaning, the limit clamp 6 is moved until the assembly slider 13 at the bottom moves to the end of the assembly groove 15, so that the anti-fouling support plate 14 can be removed from the detection chamber 3, and the anti-fouling support plate 14 can provide flexible disassembly and assembly to provide implementation conditions for convenient cleaning work.

[0032] Further as Figure 1 As shown, it is worth explaining in detail that an anti-slip groove is opened on the inner wall of the analyzer body 1, and an anti-slip buckle 4 is slidably connected inside the anti-slip groove, and one end of the anti-slip buckle 4 is fixed on the side of the detection chamber 3.

[0033] Further as Figure 1 As shown, it is worth to explain in detail that a display panel 2 is arranged on the upper part of the analyzer body 1 , and a control button is arranged on one side of the display panel 2 on the upper part of the analyzer body 1 .

[0034] In summary: the limit clamp 6 can shrink the clamping mouth and clamp the ELISA plate under the action of the rebound force of the reset spring 11, which can reduce the trouble of the ELISA plate shifting and oscillating during the detection process. The adaptive clamping effect of the limit clamp 6 can also be used for positioning ELISA plates of different sizes; when cleaning, the anti-fouling support plate 14 can be removed from the detection chamber 3, and the anti-fouling support plate 14 can provide flexible disassembly and assembly to provide implementation conditions for convenient cleaning.

[0035] What is described above is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. An enzyme-linked immunosorbent assay analyzer, comprising an analyzer body (1), characterized in that: The front port of the analyzer body (1) is provided with a detection chamber (3), the front end of the detection chamber (3) is fixed with a pull-out end plate (5), the interior of the detection chamber (3) is provided with a clamping mechanism, the clamping mechanism comprises a limit clamping plate (6), a guide slider (7) and a reset spring (11), the limit clamping plate (6) is slidably connected to the interior of the detection chamber (3), the guide slider (7) is slidably connected to the interior of the pull-out end plate (5), the reset spring (11) is arranged inside the pull-out end plate (5), the lower port of the detection chamber (3) is embedded with an anti-fouling support plate (14), and the lower end surface of the limit clamping plate (6) is fixed with two assembly sliders (13).

2. An enzyme-linked immunosorbent assay analyzer according to claim 1, characterized in that: One end of the guide slider (7) is fixed on one end surface of the limiting clamp (6), a guide slide groove (12) is provided inside the drawable end plate (5), and the guide slider (7) is slidably matched with the guide slide groove (12) of the drawable end plate (5).

3. An enzyme-linked immunosorbent assay instrument according to claim 2, characterized in that: A through sliding hole (9) is formed through one side surface of the guide sliding block (7), a guide cross bar (10) is fixed between the walls where the guide sliding groove (12) is located, and the through sliding hole (9) of the guide sliding block (7) is slidably sleeved on the surface of the guide cross bar (10).

4. An enzyme-linked immunosorbent assay analyzer according to claim 3, characterized in that: The return spring (11) is sleeved on the surface of the guide cross bar (10), one end of the return spring (11) is fixed on a side surface of the guide slider (7), and the other end of the return spring (11) is fixed on the inner wall of the drawer end plate (5).

5. An enzyme-linked immunosorbent assay analyzer according to claim 4, characterized in that: An anti-slip pad (8) is fixed to one side surface of the limiting clamping plate (6), and a clamping opening is provided between the limiting clamping plate (6) and the inner wall of the detection chamber (3).

6. An enzyme-linked immunosorbent assay analyzer according to claim 5, characterized in that: An assembly groove (15) is provided on the inner bottom wall of the anti-fouling support plate (14), and the assembly sliding block (13) is slidably connected to the assembly groove (15) of the anti-fouling support plate (14).

7. An enzyme-linked immunosorbent assay analyzer according to claim 6, characterized in that: An anti-slip groove is provided on the inner wall of the analyzer body (1), and an anti-slip buckle (4) is slidably connected inside the anti-slip groove, and one end of the anti-slip buckle (4) is fixed on the side of the detection chamber (3).

8. An enzyme-linked immunosorbent assay analyzer according to claim 7, characterized in that: A display panel (2) is arranged on the upper part of the analyzer body (1), and a control button is arranged on the upper part of the analyzer body (1) on one side of the display panel (2).