Mouse experiment table and experiment system

Abstract

The utility model provides a mouse experiment table and an experiment system, and the mouse experiment table comprises a table body which comprises a table top, and the center of the table top is provided with an experiment part; the fixing mechanism comprises a limb fixing assembly, a neck fixing assembly, a waist and abdomen fixing assembly and a tail fixing assembly, the waist and abdomen fixing assembly comprises a driving part, a pushing rod and a fixing plate, the pushing rod is arranged at the working end of the driving part, and the fixing plate is arranged at the end, facing the experiment part, of the pushing rod; and the fixing plate synchronously moves close to / away from the experiment part so as to clamp / release the mouse. The four limbs, the neck, the tail and the waist and abdomen of the mouse are clamped and fixed through the fixing mechanism, the whole mouse can be fixed on the premise that the mouse is not hurt as much as possible, therefore, the change of the concentration of biomacromolecules caused by the stress reaction of the mouse can be reduced, and meanwhile, the stability of the mouse is improved. And the waist and abdomen of the mouse can be fully exposed stably for a long time, so that the subsequent operation process is smoother.

Description

Technical Field

[0001] The utility model relates to the technical field of experimental equipment, in particular to a mouse experimental platform and an experimental system. Background Art

[0002] Mice are commonly used experimental subjects and are widely used in the field of biomedical research. They are ideal experimental models due to their tapered body, soft body, lifelong growth, long tail, and easy mobility. When conducting experimental research on mice, it is often necessary to check the health indicators of the mice and perform local tissue dissection. Before inspection and dissection, the mice need to be fixed to ensure the accuracy and safety of the experiment.

[0003] The existing method of fixing mice is mainly to fix the limbs of mice by fastening straps or pins on the laboratory table. However, this fixation method has some problems. First, the fixation effect is not good, and the mice may move their bodies due to breaking free, affecting the accuracy of the experiment. Secondly, the abdomen of the mice is not easy to expose during the struggle, which brings inconvenience to the experimental operation. In addition, the traditional fixation method may cause harm to the mice, induce stress response, and lead to changes in the concentration of biomacromolecules, thereby affecting the reliability of the experimental results.

[0004] Therefore, how to achieve all-round fixation and restriction in experimental research on mice while ensuring that the abdomen of the mice is stably and fully exposed has become an urgent problem to be solved in current experimental operations. Utility Model Content

[0005] To this end, the technical problem to be solved by the utility model is to overcome the problem in the prior art that it is difficult to achieve all-round fixation restrictions on mice during experimental research and the abdomen of the mice cannot be stably and fully exposed, and to provide a mouse experimental platform and experimental system.

[0006] In order to solve the above technical problems, the utility model provides a mouse experimental table, which includes: a table body, the table body includes a table top, and an experimental part is arranged in the center of the table top; a fixing mechanism, the fixing mechanism includes four limb fixing components, a neck fixing component, two waist and abdomen fixing components and a tail fixing component, wherein the two waist and abdomen fixing components are respectively arranged on both sides of the experimental part and correspond to the waist and abdomen positions of the experimental mouse, and any waist and abdomen fixing component includes a driving member, a pushing rod and a fixing plate, the pushing rod is arranged at the working end of the driving member, and the fixing plate is arranged at one end of the pushing rod facing the experimental part, and the two fixing plates move synchronously towards / away from the experimental part to clamp / release the mouse.

[0007] In one embodiment of the utility model, one of the waist and abdomen fixing components further includes at least one tie hole, the tie hole is connected to the table top and is located on one side of the experimental part, and the fixing plate is connected to the tie hole via a tie.

[0008] In one embodiment of the utility model, the four limb fixing components surround the experimental part and are arranged corresponding to the limbs of the mouse. Any of the limb fixing components includes a fixing ring, and the limbs of the mouse are arranged correspondingly in the four limb fixing rings.

[0009] In one embodiment of the present utility model, the limb fixing assembly further includes a first slide groove and a first slider, the first slider is slidably embedded in the first slide groove, and the fixing ring is connected to the slider.

[0010] In one embodiment of the present utility model, the limb fixing assembly further includes a back-stop mechanism, and the back-stop mechanism is disposed inside the first sliding groove.

[0011] In one embodiment of the utility model, the neck fixing assembly is arranged on one side of the experimental part and corresponds to the position of the mouse neck, and includes a first splint, a second splint and a return piece. The return piece and the first splint are connected to the second splint in sequence. The first splint, the second splint and the return piece jointly enclose a neck clamping space, and the mouse neck is located in the neck clamping space.

[0012] In one embodiment of the present invention, the neck fixing assembly further includes a second slide groove and a second slider, the second slider is slidably embedded in the second slide groove, and the second clamping plate is connected to the second slider.

[0013] In one embodiment of the present invention, the tail fixing assembly is arranged at one side of the experimental part and corresponds to the mouse tail, and includes a mounting post and a snap ring, and the snap ring is connected to the table through the mounting post.

[0014] In one embodiment of the present invention, the experimental part is configured as a blind groove sunken downward from the upper surface of the table top.

[0015] The utility model also provides an experimental system, which comprises the above-mentioned mouse experimental platform.

[0016] The above technical solution of the utility model has the following advantages compared with the prior art:

[0017] The mouse experimental platform and experimental system described in the utility model can clamp and fix the limbs, neck, tail and waist and abdomen of the mouse through a fixing mechanism, and can fix the mouse as a whole without hurting the mouse as much as possible, thereby reducing the change in the concentration of biomacromolecules caused by the stress response of the mouse. At the same time, it can also fully expose the waist and abdomen of the mouse in a long-term and stable manner, thereby making the subsequent operation process smoother. Compared with the traditional experimental platform, the present application has the advantages of high clamping stability, little harm to the experimental mouse, and easy to fully expose the waist and abdomen of the mouse. It is a new mouse experimental platform and experimental system with broad application prospects. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to make the content of the utility model more clearly understood, the utility model is further described in detail below based on specific embodiments of the utility model in combination with the accompanying drawings.

[0019] Figure 1 This is a schematic diagram of the structure of a mouse experimental platform in a preferred embodiment of the utility model;

[0020] Figure 2 yes Figure 1 Schematic diagram of the cross section at AA in the mouse experimental platform shown;

[0021] Figure 3 yes Figure 1 Schematic diagram of the cross-section at BB in the mouse experimental platform shown.

[0022] Explanation of the reference numerals in the specification: 100, table body; 110, table top; 120, experimental section; 200, fixing mechanism; 210, waist and abdomen fixing assembly; 211, driving member; 212, push rod; 213, fixing plate; 214, tie hole; 220, limb fixing assembly; 221, first slide groove; 222, first slider; 223, fixing ring; 224, anti-retraction mechanism; 230, neck fixing assembly; 231, first splint; 232, second splint; 233, return member; 234, second slider; 235, second slide groove; 240, tail fixing assembly; 241, mounting column; 242, snap ring. DETAILED DESCRIPTION

[0023] The present invention will be further described below in conjunction with the accompanying drawings and specific embodiments so that those skilled in the art can better understand the present invention and implement it, but the embodiments are not intended to limit the present invention.

[0024] Embodiment 1

[0025] See also Figure 1As shown, this embodiment provides a mouse experimental table, which includes: a table body 100, the table body 100 includes a table top 110, and an experimental part 120 is arranged at the center of the table top 110; a fixing mechanism 200, the fixing mechanism 200 includes four limb fixing components 220, a neck fixing component 230, two waist and abdomen fixing components 210 and a tail fixing component 240, wherein the two waist and abdomen fixing components 210 are respectively arranged on both sides of the experimental part 120, and correspond to the waist and abdomen positions of the experimental mouse, any waist and abdomen fixing component 210 includes a driving member 211, a pushing rod 212 and a fixing plate 213, the pushing rod 212 is arranged at the working end of the driving member 211, and the fixing plate 213 is arranged at one end of the pushing rod 212 facing the experimental part 120, and the two fixing plates 213 move synchronously towards / away from the experimental part 120 to clamp / release the mouse.

[0026] The mouse experimental platform described in the utility model can clamp and fix the limbs, neck, tail, waist and abdomen of the mouse through the fixing mechanism 200, and can fix the mouse as a whole without hurting the mouse as much as possible, thereby reducing the change in the concentration of biomacromolecules caused by the stress response of the mouse. At the same time, it can also fully expose the waist and abdomen of the mouse in a long-term and stable manner, thereby making the subsequent operation process smoother. Compared with the traditional experimental platform, the present application has the advantages of high clamping stability, little harm to the experimental mouse, and easy to fully expose the waist and abdomen of the mouse. It is a new type of mouse experimental platform with broad application prospects.

[0027] See also Figure 1 As shown, the table 110 in this embodiment is a rectangular plate with a certain thickness, and a rectangular experimental part 120 is arranged in the center thereof. Specifically, the experimental part 120 in this embodiment is arranged as a blind groove sunken downward from the upper surface of the table 110. During the actual experimental operation, the mouse is located in the blind groove. Furthermore, the bottom surface of the experimental part 120 in this embodiment can also be connected to a waste liquid recovery device, thereby preventing the waste liquid during the experiment from contaminating the table 110.

[0028] by Figure 1The mouse test bench shown is a reference object. The two waist and abdomen fixing components 210 in this embodiment are arranged at intervals on both sides of the experimental part 120 along the left and right directions. The two waist and abdomen fixing devices can squeeze and clamp the waist and abdomen of the mouse from the left and right sides, thereby reducing the activity space of the waist and abdomen of the mouse to achieve the purpose of fully exposing the abdomen of the mouse. Further, the driving member 211 in this embodiment is preferably a driving motor, and the push rod 212 and the fixed plate 213 are connected to the working end of the driving member 211 in sequence. The driving motor is used to provide driving force for the movement of the push rod 212 and the fixed plate 213. The push rod 212 is preferably a telescopic rod, thereby expanding the moving distance of the fixed plate 213 without increasing the volume of the waist and abdomen fixing component 210, so that the test bench has a larger scope of application. In other embodiments, the driving member 211 can also be set as other devices with driving effects such as a cylinder, and the utility model does not make specific restrictions on this. Specifically, one of the waist and abdomen fixing components 210 also includes at least one tie hole 214, which is connected to the table 110 and located on one side of the experimental part 120. The fixing plate 213 is connected to the tie hole 214 through a tie. In this embodiment, one of the waist and abdomen fixing components 210 includes two tie holes 214, which are arranged on the periphery of the experimental part 120 on the same side. When the waist and abdomen fixing component 210 moves to the target position, the operator can make one end of the tie pass through and connect to the corresponding fixing plate 213, and the other end connect to the corresponding tie hole 214, thereby limiting the installation position of the corresponding fixing plate 213 to avoid the squeezing and fixing effect of the fixing plate 213 being affected by the struggling activities of the mouse. In this embodiment, the fixing plate 213 extends along the length direction of the experimental part 120, thereby maximizing the fitting area and squeezing stability between the fixing plate 213 and the experimental mouse.

[0029] See also Figure 1As shown, the four limb fixing components 220 surround the experimental part 120 and are arranged corresponding to the mouse limbs. Any of the limb fixing components 220 includes a fixing ring 223, and the mouse limbs are correspondingly arranged in the four limb fixing rings 223. Further, the limb fixing component 220 also includes a first slide 221 and a first slider 222, the first slider 222 is slidably embedded in the first slide 221, and the fixing ring 223 is connected to the slider. In this embodiment, the limbs of the experimental mouse are respectively set and fixed in the four fixing rings 223, and the four first slides 221 extend in the direction away from the experimental part 120. At the same time, the movement of the first slider 222 in the first slide 221 can make the test bench suitable for mice of different sizes, thereby expanding the scope of use of the test bench. Specifically, the limb fixing component 220 also includes a stop mechanism 224, and the stop mechanism 224 is arranged inside the first slide 221. In this embodiment, the anti-recognition mechanism 224 is preferably a rack, which can increase the sliding friction of the first slider 222. When the first slider 222 is not subjected to a sufficiently large external force, the anti-recognition mechanism 224 can prevent the relative sliding between the first slider 222 and the first slide groove 221, thereby improving the stability of the mouse fixation.

[0030] See also Figure 1 and Figure 2 As shown, the neck fixing assembly 230 is arranged on one side of the experimental part 120 and is arranged corresponding to the position of the mouse neck, and includes a first clamping plate 231, a second clamping plate 232 and a return member 233. The return member 233 and the first clamping plate 231 are connected to the second clamping plate 232 in sequence. The first clamping plate 231, the second clamping plate 232 and the return member 233 jointly enclose a neck clamping space, and the mouse neck is located in the neck clamping space. Further, the neck fixing assembly 230 also includes a second slide groove 235 and a second slider 234. The second slider 234 is slidably embedded in the second slide groove 235, and the second clamping plate 232 is connected to the second slider 234. During the experiment, the operator can pull up the first clamping plate 231, thereby increasing the neck clamping space, and then insert the mouse's neck into the neck clamping space and release the pulling force on the first clamping plate 231, so that the mouse's neck can be clamped and fixed. Similarly, the second slider 234 and the second slide groove 235 can also be adaptively adjusted according to the actual size of the mouse, thereby expanding the scope of use of this experimental table.

[0031] See also Figure 1 and Figure 3As shown, the tail fixing assembly 240 is arranged on one side of the experimental part 120 and corresponds to the mouse tail, and includes a mounting post 241 and a buckle ring 242, and the buckle ring 242 is connected to the table 110 through the mounting post 241. In this embodiment, the mouse tail is inserted into the buckle ring 242, and the operator fixes the mouse tail by adjusting the circle of the buckle ring 242.

[0032] Embodiment 2

[0033] This embodiment provides an experimental system, which includes the mouse experimental platform described in the first embodiment.

[0034] In summary, the mouse experimental platform and experimental system described in the present invention can clamp and fix the mouse's limbs, neck, tail, waist and abdomen through the fixing mechanism 200, and can fix the mouse as a whole without harming the mouse as much as possible, thereby reducing the changes in the concentration of biological macromolecules caused by the stress response of the mouse. At the same time, it can also fully expose the mouse's waist and abdomen in a long-term and stable manner, thereby making the subsequent operation process smoother. Compared with traditional test benches, the present application has the advantages of high clamping stability, little harm to experimental mice, and easy to fully expose the mouse's waist and abdomen. It is a new mouse experimental platform and experimental system with broad application prospects.

[0035] Obviously, the above embodiments are merely examples for the purpose of clear explanation and are not intended to limit the implementation methods. For those skilled in the art, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to list all the implementation methods here. The obvious changes or modifications derived from these are still within the scope of protection of the invention of the utility model.

Claims

1. A mouse experimental platform, characterized in that: include: A table body, the table body comprising a table top, and a laboratory part is arranged at the center of the table top; A fixing mechanism, the fixing mechanism includes four limb fixing components, a neck fixing component, two waist and abdomen fixing components and a tail fixing component, wherein the two waist and abdomen fixing components are respectively arranged on both sides of the experimental part and correspond to the waist and abdomen positions of the experimental mouse, any of the waist and abdomen fixing components includes a driving member, a push rod and a fixing plate, the push rod is arranged at the working end of the driving member, the fixing plate is arranged at one end of the push rod facing the experimental part, and the two fixing plates move synchronously towards / away from the experimental part to clamp / release the mouse; the four limb fixing components surround the experimental part and are arranged corresponding to the limbs of the mouse, and any of the The limb fixing components all include fixing rings, and the mouse limbs are correspondingly arranged in the four limb fixing rings; the neck fixing component is arranged at one side of the experimental part and corresponding to the position of the mouse neck, and includes a first splint, a second splint and a return piece, and the return piece and the first splint are connected to the second splint in sequence, and the first splint, the second splint and the return piece jointly enclose a neck clamping space, and the mouse neck is located in the neck clamping space; the tail fixing component is arranged at one side of the experimental part and corresponding to the mouse tail, and includes a mounting column and a snap ring, and the snap ring is connected to the table through the mounting column.

2. The mouse test bench according to claim 1, characterized in that: One of the waist and abdomen fixing components also includes at least one tie hole, which is connected to the table and located on one side of the experimental part, and the fixing plate is connected to the tie hole through a tie.

3. The mouse test bench according to claim 1, characterized in that: The limb fixing assembly also includes a first sliding groove and a first sliding block, the first sliding block is slidably embedded in the first sliding groove, and the fixing ring is connected to the sliding block.

4. The mouse test bench according to claim 3, characterized in that: The limb fixing assembly further comprises a backstop mechanism, and the backstop mechanism is arranged inside the first sliding groove.

5. The mouse test bench according to claim 1, characterized in that: The neck fixing assembly further comprises a second slide groove and a second slider, wherein the second slider is slidably embedded in the second slide groove, and the second clamping plate is connected to the second slider.

6. The mouse test bench according to claim 1, characterized in that: The experimental part is configured as a blind groove sunken downward from the upper surface of the table top.

7. An experimental system, characterized in that: A mouse test bench comprising the mouse test bench described in any one of claims 1 to 6.

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