Filtering and purifying device for recombinant collagen

Abstract

The utility model discloses a filtering and purifying device for recombinant collagen, which comprises a mounting block, one side of the mounting block is provided with a squeezing assembly, the squeezing assembly comprises two-way screw rods, the outer walls of the two-way screw rods are in threaded connection with nut blocks, one end of an extension rod is fixedly connected with an extrusion block, and the other end of the extension rod is fixedly connected with a screw rod. The squeezing assembly further comprises a storage box, a filter plate is fixedly connected to the interior of the side inner wall of the storage box, and a conical block is fixedly connected to the bottom of the storage box. According to the filtering and purifying device for the recombinant collagen, after a sealing block is screwed and taken down, a raw material subjected to primary purification is guided into a storage box, a driving gear can drive two driven gears to rotate, the driven gears can drive two nut blocks to get close to each other, and then an extension rod is promoted to drive an extrusion block to extrude the raw material; and primary pulp beneficial to purification can be squeezed out.

Description

Technical Field

[0001] The utility model relates to the technical field of recombinant collagen preparation, in particular to a filtering and purifying device for recombinant collagen. Background Art

[0002] Recombinant collagen generally refers to recombinant human collagen, which is collagen prepared using DNA recombination technology. Its amino acid sequence can be designed and improved according to demand. The gene sequence of recombinant collagen is highly consistent with the human gene sequence, and has good tissue compatibility. It can be directly absorbed by the human body and participate in the construction of collagen to help with tissue repair and part filling. There are various types of collagen in the human body, and the common types are type I, type II, type III, type V and type XI. The preparation of recombinant collagen is a high-quality protein raw material obtained by separating and recombining collagen raw materials from different sources and qualities. During its preparation process, it is necessary to conduct detailed analysis and comparison of various collagen raw materials in chemistry, biology and physics, and on this basis, select suitable raw materials for combination. In this process, a series of process means such as identification, quantification, purification, and modification of collagen are required to finally obtain recombinant collagen that has undergone strict quality control.

[0003] Many raw materials for recombinant collagen are extracted from animals and plants. During the preparation process, the raw materials are often only purified once and then no longer used. However, these raw materials still contain some useful collagen substances. The useful substances can be extracted by pressing, filtering and purifying them twice. If they are directly discarded, it will cause a certain amount of waste.

[0004] Therefore, the utility model provides a filtering and purifying device for recombinant collagen to solve the above problems. Utility Model Content

[0005] In view of the deficiencies in the prior art, the utility model provides a filtering and purification device for recombinant collagen, which solves the above-mentioned problems. After the sealing block is removed by twisting, the raw materials after one purification are introduced into the storage box, and then the first servo motor is started to drive the driving gear to rotate, and the driving gear will then drive the two driven gears to rotate, and the driven gear will then drive the two nut blocks to approach each other, thereby prompting the extension rod to drive the extrusion block to extrude the raw materials, so that the raw pulp that is conducive to purification can be squeezed out, and after preliminary filtration through the filter plate, it can be guided into the cylinder through the conical block; when the squeezed raw pulp is guided into the cylinder by the conical block, the second servo motor can be started to drive the worm to rotate, and the worm will then drive the worm wheel to rotate, and the worm wheel will then drive the cylinder to rotate to generate centrifugal force, and the raw pulp will seep out through the secondary filtration of the filter cylinder, and then flow into the containing barrel through the through hole, so that the raw pulp with higher purity and less impurities can be obtained, which is conducive to subsequent processing.

[0006] To achieve the above objectives, the utility model is implemented through the following technical solutions: a recombinant collagen filtering and purification device, comprising a mounting block, a pressing assembly is arranged on one side of the mounting block, and a centrifugal filtering assembly is arranged on the outer side of the mounting block; the pressing assembly comprises a bidirectional screw rod, the bidirectional screw rod is rotatably connected between the two mounting blocks, the outer walls of the two bidirectional screw rods are threadedly connected with nut blocks, one side of the nut block is fixedly connected with an extension rod, one end of the extension rod is fixedly connected with an extrusion block, the pressing assembly also comprises a storage box, the extrusion block is slidably connected to the inner wall of the storage box, a filter plate is fixedly connected to the inside of the side inner wall of the storage box, and a conical block is fixedly connected to the bottom of the storage box.

[0007] Furthermore, a sealing block is threadedly connected to the top of the storage box.

[0008] The technical solution is adopted to seal the storage box.

[0009] Furthermore, one side of the mounting block is rotatably connected to a driven gear, and the two driven gears are fixedly connected to one end of the two bidirectional screw rods respectively. One side of the mounting block is rotatably connected to a driving gear, and the driving gear is meshed with the two driven gears. One side of the mounting block is fixedly mounted with a first servo motor, and the output shaft of the first servo motor is fixedly connected to one side of the driving gear.

[0010] By adopting the above technical solution, power is provided to drive the two bidirectional screw rods to rotate.

[0011] Furthermore, the centrifugal filter assembly includes a support plate, the top of the support plate is fixedly connected to the storage box, and an assembly block is fixedly connected between the two support plates.

[0012] By adopting the above technical solution, other important components can be installed.

[0013] Furthermore, the inner walls of the two assembly blocks are rotatably connected with a cylinder, the top of the cylinder is fixedly connected to the conical block, the inside of the cylinder is fixedly connected with a filter cylinder, the bottom side wall of the cylinder is provided with a through hole, and the centrifugal filter assembly also includes a containing barrel, which is located directly below the cylinder.

[0014] The above technical solution is adopted for secondary filtration.

[0015] Furthermore, a worm gear is fixedly connected to the outer wall of the cylinder, a worm is rotatably connected between the two support plates, the worm is meshed with the worm gear, a second servo motor is fixedly installed on one side of the support plate, and an output shaft of the second servo motor is fixedly connected to one end of the worm.

[0016] By adopting the above technical solution, power is provided to drive the cylinder to rotate and provide centrifugal force.

[0017] Beneficial Effects

[0018] The utility model provides a filtering and purifying device for recombinant collagen. Compared with the prior art, the utility model has the following beneficial effects:

[0019] 1. The filtering and purification device of the recombinant collagen is to remove the sealing block by twisting it, and then the raw materials after one purification are introduced into the storage box, and then the first servo motor is started to drive the driving gear to rotate, and the driving gear will then drive the two driven gears to rotate, and the driven gear will then drive the two nut blocks to approach each other, and then the extension rod drives the extrusion block to extrude the raw materials, so that the original pulp that is conducive to purification can be squeezed out.

[0020] 2. The filtering and purification device of the recombinant collagen can perform preliminary filtration through the filter plate and then guide it into the cylinder through the conical block; when the squeezed raw pulp is guided into the cylinder by the conical block, the second servo motor can be started to drive the worm to rotate, and the worm will then drive the worm wheel to rotate, and the worm wheel will then drive the cylinder to rotate to generate centrifugal force, and the raw pulp will seep out through the secondary filtration of the filter cylinder, and then flow into the containing barrel through the through hole, so that raw pulp with higher purity and less impurities can be obtained, which is conducive to subsequent processing. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] In order to more clearly illustrate the implementation scheme of the utility model or the technical scheme in the prior art, the drawings required for use in the implementation scheme or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some implementation schemes of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0022] Figure 1 It is a three-dimensional diagram of the external structure of the utility model;

[0023] Figure 2 It is a structural side view of the utility model;

[0024] Figure 3 This is a top view of the structure of the utility model after the storage box is removed;

[0025] Figure 4 It is a partial structural diagram of the utility model.

[0026] In the figure: 1. mounting block; 2. pressing assembly; 21. bidirectional screw; 22. nut block; 23. first servo motor; 24. driven gear; 25. extension rod; 26. driving gear; 27. extrusion block; 28. sealing block; 29. ​​filter plate; 210. conical block; 211. storage box; 3. centrifugal filter assembly; 31. support plate; 32. assembly block; 33. cylinder; 34. filter cartridge; 35. through hole; 36. holding barrel; 37. worm wheel; 38. second servo motor; 39. worm. DETAILED DESCRIPTION

[0027] It should be noted that in the description of the embodiments of the present application, the terms "front, rear", "left, right", "up, down", etc. indicating directions or positional relationships are based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation on the present application. The terms "install", "connect", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a direct connection, or an indirect connection through an intermediate medium, or it can be a connection between the two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present application can be understood according to specific circumstances.

[0028] The present application is further described in detail below through drawings and examples.

[0029] Reference Figures 1 to 4The embodiment of the present application provides a filtering and purifying device for recombinant collagen, comprising a mounting block 1, a pressing assembly 2 is arranged on one side of the mounting block 1, and a centrifugal filter assembly 3 is arranged on the outside of the mounting block 1; the pressing assembly 2 comprises a bidirectional screw rod 21, the bidirectional screw rod 21 is rotatably connected between the two mounting blocks 1, the outer walls of the two bidirectional screw rods 21 are threadedly connected with a nut block 22, one side of the nut block 22 is fixedly connected with an extension rod 25, and one end of the extension rod 25 is fixedly connected with an extrusion block 27, the pressing assembly 2 also comprises a storage box 211, the extrusion block 27 is slidably connected to the inner wall of the storage box 211, a filter plate 29 is fixedly connected to the inner side wall of the storage box 211, and a conical block 210 is fixedly connected to the bottom of the storage box 211. The top of the storage box 211 is threadedly connected with a sealing block 28. A driven gear 24 is rotatably connected to one side of the mounting block 1, and the two driven gears 24 are fixedly connected to one end of the two bidirectional screw rods 21 respectively. A driving gear 26 is rotatably connected to one side of the mounting block 1, and the driving gear 26 meshes with the two driven gears 24. A first servo motor 23 is fixedly installed on one side of the mounting block 1, and the output shaft of the first servo motor 23 is fixedly connected to one side of the driving gear 26.

[0030] During specific implementation: after removing the sealing block 28 by twisting it, the raw materials after one purification are introduced into the storage box 211, and then the first servo motor 23 is started to drive the driving gear 26 to rotate, and the driving gear 26 will then drive the two driven gears 24 to rotate, and the driven gear 24 will then drive the two nut blocks 22 to approach each other, and then the extension rod 25 drives the extrusion block 27 to extrude the raw materials, so that the raw pulp that is conducive to purification can be squeezed out, and after preliminary filtration through the filter plate 29, it can be guided into the cylinder 33 through the conical block 210.

[0031] Reference Figures 1 to 4 In one aspect of the present embodiment, the centrifugal filter assembly 3 includes a support plate 31, the top of the support plate 31 is fixedly connected to the storage box 211, and an assembly block 32 is fixedly connected between the two support plates 31. The inner walls of the two assembly blocks 32 are rotatably connected with a cylinder 33, the top of the cylinder 33 is fixedly connected to the conical block 210, the inside of the cylinder 33 is fixedly connected with a filter cylinder 34, and the bottom side wall of the cylinder 33 is provided with a through hole 35. The centrifugal filter assembly 3 also includes a container 36, which is located directly below the cylinder 33. The outer wall of the cylinder 33 is fixedly connected with a worm wheel 37, and a worm 39 is rotatably connected between the two support plates 31, and the worm 39 is meshed with the worm wheel 37. A second servo motor 38 is fixedly installed on one side of the support plate 31, and the output shaft of the second servo motor 38 is fixedly connected to one end of the worm 39.

[0032] In specific implementation: after the squeezed raw pulp is guided into the cylinder 33 by the conical block 210, the second servo motor 38 can be started to drive the worm 39 to rotate, and the worm 39 will then drive the worm wheel 37 to rotate, and the worm wheel 37 will then drive the cylinder 33 to rotate to generate centrifugal force, and the raw pulp will seep out through the secondary filtration of the filter cylinder 34, and then flow into the containing barrel 36 through the through hole 35, so that raw pulp with higher purity and less impurities can be obtained, which is conducive to subsequent processing.

[0033] All electrical equipment in this solution are powered by an external power supply.

[0034] Working principle: After removing the sealing block 28 by twisting it, the raw materials after one purification are introduced into the storage box 211, and then the first servo motor 23 is started to drive the driving gear 26 to rotate, and the driving gear 26 will then drive the two driven gears 24 to rotate, and the driven gear 24 will then drive the two nut blocks 22 to approach each other, and then the extension rod 25 drives the extrusion block 27 to squeeze these raw materials, so that the original pulp that is conducive to purification can be squeezed out, and the initial filtration can be carried out through the filter plate 29, and then it can be passed The conical block 210 guides the squeezed pulp into the cylinder 33. After the squeezed pulp is guided into the cylinder 33 by the conical block 210, the second servo motor 38 can be started to drive the worm 39 to rotate. The worm 39 will then drive the worm wheel 37 to rotate. The worm wheel 37 will then drive the cylinder 33 to rotate and generate centrifugal force. The pulp will seep out through the secondary filtration of the filter cylinder 34 and then flow into the containing barrel 36 through the through hole 35. Thus, pulp with higher purity and less impurities can be obtained, which is beneficial for subsequent processing.

[0035] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0036] Although the embodiments of the present application have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present application, and that the scope of the present application is defined by the appended claims and their equivalents.

Claims

1. A filtering and purification device for recombinant collagen, comprising a mounting block (1), characterized in that: A pressing assembly (2) is arranged on one side of the mounting block (1), and a centrifugal filter assembly (3) is arranged on the outer side of the mounting block (1); the pressing assembly (2) comprises a bidirectional screw rod (21), the bidirectional screw rod (21) is rotatably connected between the two mounting blocks (1), the outer walls of the two bidirectional screw rods (21) are threadedly connected with nut blocks (22), one side of the nut block (22) is fixedly connected with an extension rod (25), one end of the extension rod (25) is fixedly connected with an extrusion block (27), the pressing assembly (2) also comprises a storage box (211), the extrusion block (27) is slidably connected to the inner wall of the storage box (211), a filter plate (29) is fixedly connected to the inner side wall of the storage box (211), and a conical block (210) is fixedly connected to the bottom of the storage box (211).

2. The filtration and purification device for recombinant collagen according to claim 1, characterized in that: The top of the storage box (211) is threadedly connected with a sealing block (28).

3. The filtration and purification device for recombinant collagen according to claim 1, characterized in that: One side of the mounting block (1) is rotatably connected to a driven gear (24), and the two driven gears (24) are fixedly connected to one end of two bidirectional screw rods (21) respectively; one side of the mounting block (1) is rotatably connected to a driving gear (26), and the driving gear (26) is meshed with the two driven gears (24); one side of the mounting block (1) is fixedly mounted with a first servo motor (23), and the output shaft of the first servo motor (23) is fixedly connected to one side of the driving gear (26).

4. The filtration and purification device for recombinant collagen according to claim 1, characterized in that: The centrifugal filter assembly (3) comprises a support plate (31), the top of the support plate (31) is fixedly connected to the storage box (211), and an assembly block (32) is fixedly connected between the two support plates (31).

5. The filtration and purification device for recombinant collagen according to claim 4, characterized in that: The inner walls of the two assembly blocks (32) are rotatably connected to a cylinder (33); the top of the cylinder (33) is fixedly connected to the conical block (210); the interior of the cylinder (33) is fixedly connected to a filter cartridge (34); a through hole (35) is provided on the bottom side wall of the cylinder (33); and the centrifugal filter assembly (3) further comprises a container barrel (36) which is located directly below the cylinder (33).

6. The filtration and purification device for recombinant collagen according to claim 5, characterized in that: A worm wheel (37) is fixedly connected to the outer wall of the cylinder (33); a worm (39) is rotatably connected between the two support plates (31); the worm (39) is meshed with the worm wheel (37); a second servo motor (38) is fixedly mounted on one side of the support plate (31); an output shaft of the second servo motor (38) is fixedly connected to one end of the worm (39).

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