Cell culture plate sample adding positioning device

Abstract

The utility model relates to the technical field of cell culture plate sample adding and positioning, in particular to a cell culture plate sample adding and positioning device which comprises a placing frame, a plurality of groups of culture frames are arranged on the inner side of the placing frame, a plurality of groups of culture holes are formed in the culture frames, and marking and positioning mechanisms are arranged on the culture frames and the placing frame. The marking and positioning mechanism comprises a marking assembly, a positioning assembly and an adjusting assembly, the marking assembly is used for marking culture holes for sample adding, the positioning assembly is used for positioning a row of culture holes for sample adding, and the adjusting assembly is used for adjusting indication positions of part of the positioning assembly; the marking assembly comprises a plurality of groups of movable grooves formed in the top end of the culture frame, and an abutting groove is formed in the culture frame and located on one side of the movable grooves; the device has a simple structure, is convenient to operate, effectively positions and marks the culture holes with samples added, is convenient for a worker to judge which hole is filled with liquid medicine more easily, and ensures an experimental result.

Description

Technical Field

[0001] The utility model relates to the technical field of sample adding and positioning of a cell culture plate, in particular to a sample adding and positioning device of a cell culture plate. Background Art

[0002] Cell culture plates are commonly used experimental consumables in cell experiments, especially in experiments involving cell growth activity, such as MTT experiments, XTT experiments, CCK-8 experiments, etc. Since the above experiments mostly use 96-well cell culture plates, this article mainly uses 96-well plates as examples. These experiments all require very strict liquid addition requirements. Due to the large number of wells on 96-well plates, it is easy to make mistakes during liquid addition operations. For example, when drug A has been added to each well and drug B needs to be added to each well, if drug B has the same color as drug A, it is often impossible to distinguish which well has been added and which well has not been added during the liquid addition process, resulting in repeated liquid addition or missed addition, which seriously affects the experimental results. Utility Model Content

[0003] The utility model aims to provide a sample adding and positioning device for a cell culture plate to solve the problems raised in the above-mentioned background technology.

[0004] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0005] A cell culture plate loading and positioning device comprises a placement rack, wherein a plurality of culture racks are arranged and installed on the inner side of the placement rack, and a plurality of culture wells are arranged and provided on the culture rack, and a marking positioning mechanism is installed on the culture rack and the placement rack, and the marking positioning mechanism comprises a marking component, a positioning component and an adjusting component, the marking component is used to mark the culture wells for loading, the positioning component is used to locate a row of culture wells for loading, and the adjusting component is used to adjust the indicated position of part of the positioning component, the marking component comprises a plurality of movable grooves opened on the top of the culture rack, a pressing button is slidably connected to the inner side of the movable groove, an abutting groove is opened on one side of the movable groove inside the culture rack, an abutting block slidably connected to the abutting groove is installed on one end of the pressing button, a reset spring is installed between the two ends of one side of the abutting block and the inner wall of the abutting groove, a clamping groove is opened on one side of the abutting groove inside the culture rack, and the abutting groove is communicated with the inner side of the clamping groove, The cam is provided with a plurality of locking plates at the bottom end, the locking plate is provided with a plurality of locking plates at the bottom end, the plurality of locking plates are provided with a plurality of locking plates at the bottom end.

[0006] As a preferred solution of the utility model, the positive cross-section of the clamping block of the side cross-section of the abutting block is "U"-shaped, and the ends of the clamping block and the abutting block are both provided with inclined surfaces that fit each other.

[0007] As a preferred solution of the utility model, the positioning assembly includes multiple groups of first positioning plates arranged and installed on the adjustment plate, the bottom end of the first positioning plate is installed with an indicator arrow, and one side of the inner wall of the placement rack is arranged and installed with multiple groups of second positioning plates corresponding to the culture hole positions.

[0008] As a preferred solution of the utility model, the top surfaces of the first positioning plate and the second positioning plate are both printed with Arabic numerals, and the surface of the card plate is coated with red pigment.

[0009] Compared with the prior art, the beneficial effects of the utility model are:

[0010] In the utility model, after adding a sample to one of the culture wells, the button is pressed to trigger the marking component, so that the first spring drives the marking frame to pop out, and the red card plate inside the marking frame is more eye-catching, which can remind the staff that the culture well has been added with a sample, and then the adjustment component is used to adjust part of the positioning component to the top of a row of culture wells where the sample is specified for addition, and the Arabic numerals printed on the positioning component are used to remind the staff that the row of culture wells is being added with the sample. The utility model has a simple structure and is easy to operate. It can effectively locate and mark the culture wells where the sample has been added, so that the staff can more easily judge which well has been added with the medicine solution, thereby ensuring the experimental results. BRIEF DESCRIPTION OF THE DRAWINGS

[0011] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0012] Figure 2 This is a schematic diagram of a partial cross-sectional structure of the culture rack of the utility model;

[0013] Figure 3 For this utility model Figure 1 Schematic diagram of the enlarged structure of part A.

[0014] In the figure: 1. placement rack; 2. culture rack; 3. culture hole; 4. press button; 5. abutment block; 6. reset spring; 7. clamping block; 8. connecting plate; 9. marking frame; 10. clamping plate; 11. mounting rod; 12. adjusting cylinder; 13. threaded rod; 14. adjusting plate; 15. handle; 16. first positioning plate; 17. indicator arrow; 18. second positioning plate. DETAILED DESCRIPTION

[0015] The technical solutions in the embodiments of the utility model will be clearly and completely described below in conjunction with the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model.

[0016] Example:

[0017] See also Figure 1-Figure 3 , the utility model provides a technical solution:

[0018] A cell culture plate sample loading and positioning device comprises a placement rack 1, wherein a plurality of groups of culture racks 2 are arranged and installed inside the placement rack 1, and a plurality of groups of culture wells 3 are arranged and opened on the culture rack 2. A marking and positioning mechanism is installed on the culture rack 2 and the placement rack 1, and the marking and positioning mechanism comprises a marking component, a positioning component and an adjusting component. The marking component is used to mark the culture wells 3 for sample loading, the positioning component is used to locate a row of culture wells 3 for sample loading, and the adjusting component is used to adjust the indicated position of part of the positioning component. When the device is in use, after adding a sample to one of the culture wells 3, a pressing button 4 is pressed to trigger the marking component, so that a first spring drives a marking frame 9 to pop out, and a red card plate 10 inside the marking frame 9 is relatively eye-catching, which can remind a staff member that the culture well 3 has been loaded with samples, and then the adjusting component is used to adjust part of the positioning component to the top of a row of culture wells 3 for designated sample loading for positioning, and the Arabic numerals printed on the positioning component are used to remind the staff member that the row of culture wells 3 is being loaded with samples. The device has a simple structure and is easy to operate, and can effectively locate and mark the culture wells 3 for sample loading, so that it is easier for the staff member to judge which well has been loaded with liquid medicine, thereby ensuring the experimental results.

[0019] In this embodiment, if Figure 1 , Figure 2 and Figure 3 As shown, the marking component includes multiple groups of movable grooves opened at the top of the culture rack 2, and a pressure button 4 is slidably connected to the inner side of the movable groove. An abutting groove is opened inside the culture rack 2 at one side of the movable groove, and an abutting block 5 slidably connected to the abutting groove is installed at one end of the pressure button 4. Reset springs 6 are installed between the two ends of one side of the abutting block 5 and the inner wall of the abutting groove. A card slot is opened inside the culture rack 2 at one side of the abutting groove, and the abutting groove is communicated with the inner side of the card slot. A card block 7 is slidably connected to the inner side of the card slot. A connecting groove is opened on one side of the culture rack 2, and a connecting plate 8 is carded on the inner side of the connecting groove. The connecting groove is communicated with the inner side of the card slot, and one end of the card block 7 is fixedly connected to one side of the connecting plate 8. First, press the pressure button 4 on one side of the culture well 3 where the sample has been added, so that the abutting block 5 retracts and squeezes the reset spring 6. After the raised end of the abutting block 5 is separated from the U-shaped recessed part of the card block 7, the first spring loses resistance and cooperates with the connecting plate 8 to drive the card block 7 and the marking frame 9 to pop out, and the red card plate 10 is displayed to achieve the marking effect.

[0020] In this embodiment, if Figure 1 , Figure 2 and Figure 3As shown, the positive cross-section of the card block 7 of the side section of the abutment block 5 is "U"-shaped, and the end where the card block 7 and the abutment block 5 are abutted is provided with inclined surfaces that fit each other, a marking frame 9 is installed on one side of the connecting plate 8, and a mounting groove slidably connected to the marking frame 9 is provided on one side of the culture rack 2, a first spring is installed between the other end of the marking frame 9 and the inner wall of the mounting groove, and a card plate 10 is embedded and installed on the inner side of the marking frame 9, and then, the pressing button 4 is pressed again, and then the connecting plate 8 is pressed to let the first spring retract again, so that the card block 7 is stuck in the slot, so that the inclined surfaces of the card block 7 and the abutment block 5 abut against each other, forcing the abutment block 5 to retract and squeeze the reset spring 6, and after the card block 7 is fully stuck, the protruding end of the abutment block 5 pops out and abuts against the recessed part of the card block 7 to prevent its movement, and at the same time, the marking frame 9 enters the inner side of the mounting groove to complete the reset.

[0021] In this embodiment, if Figure 1 As shown, the adjustment component includes a mounting rod 11 fixedly connected to one end of the top of the placement frame 1, an adjustment cylinder 12 is installed on the outer side of one end of the mounting rod 11, an adjustment groove is opened on one side of the adjustment cylinder 12, a threaded rod 13 is rotatably connected to the inner side of the adjustment groove, an adjustment plate 14 is threadedly connected to the outer side of the threaded rod 13, the adjustment plate 14 is slidably connected to the adjustment groove, one end of the adjustment cylinder 12 is rotatably connected to a handle 15, one end of the handle 15 extends to the inner side of the adjustment groove and is fixedly connected to one end of the threaded rod 13, the positioning component includes a plurality of groups of first positioning plates 16 arranged and installed on the adjustment plate 14, and the first positioning plates 16 are arranged and installed on the adjustment plate 14. An indicating arrow 17 is installed at the bottom end of the positioning plate 16, and a plurality of second positioning plates 18 corresponding to the positions of the culture holes 3 are arranged on one side of the inner wall of the placement rack 1. Arabic numerals are printed on the top surfaces of the first positioning plate 16 and the second positioning plate 18, and the surface of the card plate 10 is coated with red paint. Furthermore, the rotating handle 15 drives the threaded rod 13 to rotate, so that the adjustment plate 14 slides on the inside of the adjustment groove, and then drives the first positioning plate 16 to move. When the indicating arrow 17 is located above a row of culture holes 3 where samples need to be added, the movement can be stopped, thereby prompting the personnel that samples are currently being added to the row of culture holes 3.

[0022] The implementation principle of the sample loading and positioning device for a cell culture plate of the present application embodiment is as follows: the push button 4 on one side of the sample loaded culture hole 3 is pressed to allow the abutment block 5 to retract and squeeze the reset spring 6. After the protruding end of the abutment block 5 is separated from the U-shaped recess of the clamping block 7, the first spring loses resistance and cooperates with the connecting plate 8 to drive the clamping block 7 and the marking frame 9 to pop out, and the red clamping plate 10 is displayed to achieve the marking effect. The push button 4 is pressed again, and then the connecting plate 8 is pressed to allow the first spring to retract again, so that the clamping block 7 is clamped into the clamping slot, so that the clamping block 7 and the abutment block 5 are connected. The inclined surfaces of the two abut against each other, forcing the abutment block 5 to retract and squeeze the reset spring 6. After the block 7 is fully inserted, the protruding end of the abutment block 5 pops out and abuts against the recessed part of the block 7 to block its movement. At the same time, the marking frame 9 enters the inner side of the installation groove to complete the reset. The rotating handle 15 drives the threaded rod 13 to rotate, so that the adjustment plate 14 slides on the inner side of the adjustment groove, and then drives the first positioning plate 16 to move. When the indicator arrow 17 is located above the row of culture holes 3 where samples need to be added, it can stop, which has the effect of reminding the personnel that samples are currently being added to the row of culture holes 3.

[0023] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A cell culture plate sample loading and positioning device, comprising a placement rack (1), characterized in that: A plurality of culture racks (2) are arranged and installed inside the placement rack (1), and a plurality of culture wells (3) are arranged and opened on the culture rack (2). A marking and positioning mechanism is installed on the culture rack (2) and the placement rack (1), and the marking and positioning mechanism comprises a marking component, a positioning component and an adjustment component. The marking component is used to mark the culture wells (3) for sample addition, the positioning component is used to locate a row of culture wells (3) for sample addition, and the adjustment component is used to adjust the indicated position of part of the positioning component. The marking component comprises a positioning component opened on the culture rack (2 ) at the top, a plurality of movable grooves are provided at the inner side of the movable grooves, a pressing button (4) is slidably connected thereto, an abutting groove is provided inside the culture rack (2) at one side of the movable groove, an abutting block (5) slidably connected to the abutting groove is installed at one end of the pressing button (4), a return spring (6) is installed between the two ends of one side of the abutting block (5) and the inner wall of the abutting groove, a clamping groove is provided inside the culture rack (2) at one side of the abutting groove, the abutting groove is communicated with the inner side of the clamping groove, a clamping block (7) is slidably connected thereto, and one side of the culture rack (2) is provided with a A connecting groove is provided, the inner side of the connecting groove is clamped with a connecting plate (8), the connecting groove is communicated with the inner side of the clamping groove, one end of the clamping block (7) is fixedly connected to one side of the connecting plate (8), the adjustment component comprises a mounting rod (11) fixedly connected to one end of the top of the placement rack (1), an adjustment cylinder (12) is installed on the outer side of one end of the mounting rod (11), one side of the adjustment cylinder (12) is provided with an adjustment groove, the inner side of the adjustment groove is rotatably connected with a threaded rod (13), the outer side of the threaded rod (13) is threadedly connected to the adjustment plate (1 4), the adjustment plate (14) is slidably connected to the adjustment groove, one end of the adjustment cylinder (12) is rotatably connected to a handle (15), one end of the handle (15) extends to the inner side of the adjustment groove and is fixedly connected to one end of the threaded rod (13), the positioning assembly includes a plurality of groups of first positioning plates (16) arranged and installed on the adjustment plate (14), the bottom end of the first positioning plate (16) is installed with an indicating arrow (17), and a plurality of groups of second positioning plates (18) corresponding to the positions of the culture holes (3) are arranged and installed on one side of the inner wall of the placement rack (1).

2. A cell culture plate sample loading and positioning device according to claim 1, characterized in that: The front cross-sections of the clamping block (7) of the side cross-section of the abutting block (5) are all in a "U" shape, and the ends of the clamping block (7) and the abutting block (5) are both provided with mutually fitting inclined surfaces.

3. A cell culture plate sample loading and positioning device according to claim 2, characterized in that: A marking frame (9) is installed on one side of the connecting plate (8), a mounting groove slidably connected to the marking frame (9) is opened on one side of the culture rack (2), a first spring is installed between the other end of the marking frame (9) and the inner wall of the mounting groove, and a clamping plate (10) is embedded and installed on the inner side of the marking frame (9).

4. A cell culture plate sample loading and positioning device according to claim 3, characterized in that: The top surfaces of the first positioning plate (16) and the second positioning plate (18) are both printed with Arabic numerals, and the surface of the card plate (10) is coated with red pigment.

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