Orifice plate type automatic inoculation instrument
The orifice plate automatic inoculation instrument solves the problems of low inoculation efficiency and high medium consumption in the prior art through the combination of rotating jaw robot arm and liquid-adding robot arm, and achieves the effect of high-throughput sample processing and medium saving. .
Patent Information
- Application Number
- CN202421028353.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-13
- Publication Date
- 2025-01-07
- Estimated Expiration
- 2034-05-13
AI Technical Summary
The existing automatic cell seeder has low inoculation efficiency, high-media consumption and cannot achieve high-throughput inoculation.
Using an automatic inoculation device for the well plate type, cell culture well plates are used to replace traditional cell culture tubes, and automatic barcode entry, blood collection tube clamping, culture medium absorption and cell sample transfer are achieved through rotating the jaw clamping robot arm and liquid addition robot arm, combined with ultraviolet disinfection Module and exhaust gas adsorption treatment module to optimize sample processing flow.
It greatly improves sample processing throughput and efficiency, saves the use of culture medium, shortens the inoculation process, and ensures the efficient use of experimental consumables and biosafety.
Smart Images

Figure CN222313169U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to a biological sample processing instrument, in particular to a well plate type automatic inoculation instrument. Background Art
[0002] The main process of chromosome karyotype analysis of peripheral blood lymphocytes includes: inoculation and culture of peripheral blood lymphocytes, cell harvesting, chromosome preparation, banding and karyotype analysis, etc. The inoculation process can be done manually or by automated instruments. At present, such biological sample processing instruments have initially realized the automation of sample processing.
[0003] Chinese patent CN218290939U discloses an automatic cell inoculation instrument, including an automatic opening module for blood collection tubes, an automatic pipetting module, an automatic barcode entry module for blood collection tubes, parallel electric grippers, a cell culture tube positioning and barcode entry module, a HEPA filtration module, an ultraviolet disinfection module, a control system, and a human-machine interface. The cell inoculation instrument uses traditional cell culture tubes and cell culture tube holders, and the cell culture tubes need to be labeled and the information needs to be scanned and entered each time. The inoculation process is cumbersome and the medium consumption is high, making it difficult to achieve high-throughput automated inoculation. Utility Model Content
[0004] In view of the problems existing in the prior art, the utility model provides a well plate type automatic inoculator, which is used to solve the technical problems of low inoculation efficiency, high culture medium consumption and inability to achieve high-throughput inoculation of current automatic cell inoculators.
[0005] In order to achieve the above purpose, the utility model adopts the following technical solutions:
[0006] A well plate type automatic inoculator, comprising a sample processing platform, a rotating gripper mechanical arm and a liquid adding mechanical arm;
[0007] The sample processing platform is provided with a blood collection tube sample rack, a blood collection tube clamping device, a culture medium vessel, a pipette tip placement box and a cell culture well plate; a plurality of blood collection tubes are arranged on the blood collection tube sample rack, and a plurality of pipette tips are arranged on the pipette tip placement box;
[0008] The rotating clamping claw mechanical arm is arranged above the sample processing platform, and is provided with a blood collection tube automatic barcode entry module and a blood collection tube transfer and cover opening module. The rotating clamping claw mechanical arm can move between the blood collection tube sample rack and the blood collection tube clamping device. The blood collection tube automatic barcode entry module sequentially scans and obtains the barcodes of multiple blood collection tubes on the blood collection tube sample rack, and the blood collection tube transfer and cover opening module clamps and transfers each blood collection tube to the blood collection tube clamping device and opens the bottle cap of the blood collection tube fixed on the blood collection tube clamping device.
[0009] The liquid-adding robot arm is arranged above the sample processing platform, and can move between the blood collection tube clamping device, the culture medium vessel, the pipette tip placement box and the cell culture well plate. The liquid-adding robot arm absorbs a pipette tip on the pipette tip placement box and absorbs culture medium from the culture medium vessel, and then transfers the absorbed culture medium to the cell culture well plate. The liquid-adding robot arm inserts the pipette tip into the blood collection tube on the blood collection tube clamping device and absorbs the cell sample, and then transfers the cell sample to the cell culture well plate to mix with the culture medium.
[0010] Furthermore, the rotating clamping robot arm includes a first three-dimensional motion mechanism and a blood collection tube clamping mechanism; the first three-dimensional motion mechanism is used to drive the blood collection tube clamping mechanism to perform three-dimensional movement on the blood collection tube, and the blood collection tube transfer and opening module is provided with the blood collection tube clamping mechanism, and the blood collection tube clamping mechanism is used to grasp the bottle cap of the blood collection tube, so that the grasped blood collection tube moves between the blood collection tube sample rack and the blood collection tube clamping device.
[0011] Furthermore, the cell culture well plate comprises a well plate holder and a plurality of well plate slots, and the well plate slots are mounted on the well plate holder.
[0012] Furthermore, the well plate holder is in a rectangular shape, with bayonet ports symmetrically provided on both sides of the well plate holder, and card blocks symmetrically provided on both sides of each well plate slot, and multiple culture slots are sequentially provided along the extension direction of the well plate slot; when multiple well plate slots are clamped on the well plate holder, the card blocks are clamped in the bayonet ports.
[0013] Furthermore, the card block is in an inverted L-shape, and is provided with an insertion portion and a handle portion. The card block is arranged on one side of the slot of the orifice plate and is flush with the slot of the orifice plate. The depth of the slot is equal to the length of the insertion portion, and the handle portion is located on the outside of the slot.
[0014] Furthermore, a pipette tip recovery box is also provided on the sample processing platform. The pipette tip recovery box is located on one side of the pipette tip placement box and can receive the pipette tips removed by the liquid adding robot arm.
[0015] Furthermore, the liquid-adding robot arm includes a second three-dimensional motion mechanism and a pipetting module; the second three-dimensional motion mechanism drives the pipetting module to move, and the pipetting module is used to automatically remove the pipette tip, transfer the culture medium in the culture medium vessel to the cell culture well plate, mix the cell sample in the blood collection tube on the blood collection tube clamping device, and transfer the cell sample to the cell culture well plate containing the culture medium.
[0016] Furthermore, the well plate automatic inoculator also includes an equipment cabin, a processing flow control device and a supporting mechanism, the sample processing platform is arranged at the bottom of the inner cavity of the equipment cabin, the two ends of the supporting mechanism are connected to the equipment cabin and are located above the sample processing platform, the rotating gripper robot arm and the liquid adding robot arm are installed on the supporting mechanism, the processing flow control device is arranged outside the equipment cabin, and the processing flow control device is signal-connected to the rotating gripper robot arm and the liquid adding robot arm.
[0017] Furthermore, the orifice plate automatic inoculator also includes a waste gas adsorption treatment module; the waste gas adsorption treatment module is arranged on the top of the equipment cabin, and the waste gas adsorption treatment module serves as an absorption and transportation device for the gas in the equipment cabin; the waste gas adsorption treatment module includes a waste gas external exhaust fan, a waste gas adsorbent and a fan outer frame fixing frame; the waste gas external exhaust fan is installed on the top of the equipment cabin through the fan outer frame fixing frame; the waste gas adsorbent is arranged below the waste gas external exhaust fan.
[0018] Furthermore, the well plate automatic inoculator also includes an ultraviolet disinfection module, which is composed of a multi-tube ultraviolet lamp and is used to disinfect the operating space area in the equipment cabin. The ultraviolet lamp is installed on the side wall or under the top of the equipment cabin, and the switch of the ultraviolet lamp is controlled by connecting to the control system signal.
[0019] The present application provides a well plate type automatic inoculator, which uses a cell culture well plate to replace the traditional cell culture tube. The volume of a single hole in the multi-well plate is much smaller than that of the culture tube, which saves the use of culture medium and reduces the space occupied by the instrument. The cell culture well plate is preferably detachable and adjustable, so that the number of cell culture tanks in the cell culture well plate is equivalent to the number of blood collection tubes, further improving the efficiency of the use of experimental consumables. A single culture tube is integrated into a smaller multi-well plate. During inoculation, there is no need to label the culture tube separately and scan the code to enter the information. Only the information of the multi-well plate needs to be entered once, which shortens the inoculation process and greatly improves the sample processing throughput and sample processing efficiency. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] Figure 1 This is a schematic diagram of the overall structure of the well plate type automatic inoculator of the utility model;
[0021] Figure 2 It is a front view of the well plate type automatic inoculator of the utility model;
[0022] Figure 3 This is a schematic diagram of the structure of the rotary gripper mechanical arm of the utility model;
[0023] Figure 4 This is a schematic diagram of the structure of the liquid adding mechanical arm of the utility model;
[0024] Figure 5 This is a schematic diagram of the structure of the cell culture well plate of the utility model;
[0025] Figure 6 This is a structural schematic diagram of the orifice plate holder of the utility model;
[0026] Figure 7 This is a structural schematic diagram of the orifice plate slot of the utility model;
[0027] Figure 8 This is a schematic diagram of the structure of the waste gas adsorption treatment module of the utility model;
[0028] Fig. 9 It is a structural schematic diagram of the ultraviolet disinfection module of the utility model.
[0029] The markings in the figure are as follows:
[0030] Sample processing platform 1, blood collection tube 10, blood collection tube sample rack 11, blood collection tube clamping device 12, culture medium vessel 13, pipette tip placement box 14, cell culture well plate 15, well plate holder 151, well plate slot 152, bayonet 153, card block 154, insertion part 1541, handle part 1542, culture tank 155, pipette tip recovery box 16, rotating clamping claw robot arm 2, blood collection tube automatic bar code entry module 21, blood collection tube transfer and opening module 22, first three-dimensional motion mechanism 23, liquid adding robot arm 3, second three-dimensional motion mechanism 31, pipetting module 32, equipment cabin 4, support mechanism 5, exhaust gas adsorption treatment module 6, exhaust gas external exhaust fan 61, exhaust gas adsorbent 62, fan outer frame fixing frame 63, ultraviolet disinfection module 7, ultraviolet lamp 71. DETAILED DESCRIPTION
[0031] The utility model is further described below in conjunction with the accompanying drawings.
[0032] Example 1.
[0033] In this embodiment, see Figure 1 , Figure 2 A well plate type automatic inoculator comprises a sample processing platform 1, a rotating gripper robot arm 2 and a liquid adding robot arm 3.
[0034] See also Figure 1 , Figure 2 The sample processing platform 1 is provided with a blood collection tube sample rack 11, a blood collection tube clamping device 12, a culture medium vessel 13, a pipette tip placement box 14 and a cell culture well plate 15; a plurality of blood collection tubes 10 are arranged on the blood collection tube sample rack 11, and a plurality of pipette tips are arranged on the pipette tip placement box 14.
[0035] See also Figure 3The rotating jaw robot arm 2 is arranged above the sample processing platform 1, and is provided with a blood collection tube automatic barcode entry module 21 and a blood collection tube transfer and cover opening module 22. The rotating jaw robot arm 2 can move between the blood collection tube sample rack 11 and the blood collection tube clamping device 12. The blood collection tube automatic barcode entry module 21 sequentially scans and obtains the barcodes of multiple blood collection tubes 10 on the blood collection tube sample rack 11, and the blood collection tube transfer and cover opening module 22 clamps and transfers each blood collection tube 10 to the blood collection tube clamping device 12 and opens the bottle cap of the blood collection tube 10 fixed on the blood collection tube clamping device 12.
[0036] The blood collection tube automatic barcode entry module 21 is a one-dimensional barcode module, which is used to automatically enter the barcode of the blood collection tube sample; preferably, the blood collection tube automatic barcode entry module 21 can be rotated to align with the barcode of the blood collection tube 10 on the blood collection tube sample rack 11 to realize the automation of sample barcode entry.
[0037] See also Figure 1 , Figure 2 The sample processing platform 1 is also provided with a pipette tip recovery box 16 , which is located on one side of the pipette tip placement box 14 and can receive the pipette tips removed by the liquid adding robot 3 .
[0038] Example 2.
[0039] This embodiment is basically the same as the above embodiment, with the following features:
[0040] See also Figure 1 , Figure 2 The liquid-adding robot 3 is arranged above the sample processing platform 1, and the liquid-adding robot 3 can move between the blood collection tube clamping device 12, the culture medium vessel 13, the pipette tip placement box 14 and the cell culture well plate 15. The liquid-adding robot 3 absorbs a pipette tip on the pipette tip placement box 14 and absorbs the culture medium from the culture medium vessel 13, and then transfers the absorbed culture medium to the well plate slot 152 of the cell culture well plate 15. The liquid-adding robot 3 inserts the pipette tip into the blood collection tube 10 on the blood collection tube clamping device 12 and absorbs the cell sample, and then transfers the cell sample to the well plate slot 152 of the cell culture well plate 15 to mix with the culture medium.
[0041] See also Figure 4 , Figure 5The liquid adding robot arm 3 includes a second three-dimensional motion mechanism 31 and a pipetting module 32; the second three-dimensional motion mechanism 31 drives the pipetting module 32 to move, and the pipetting module 32 is used to automatically take off the pipette tip, transfer the culture medium in the culture medium vessel 13 to the well plate slot 152 of the cell culture well plate 15, mix the cell sample in the blood collection tube 10 on the blood collection tube clamping device, and transfer the cell sample to the well plate slot 152 of the cell culture well plate 15 containing the culture medium.
[0042] The second three-dimensional motion mechanism 31 is an XYZ three-dimensional motion mechanism, and the pipetting module 32 is composed of an electric sample pump and a sensor. The electric sample pump realizes liquid suction and discharge through forward and reverse motion. The sensor is composed of a pressure sensor and a capacitance sensor. The pressure sensor is used to detect the pressure change in the pipeline to detect the volume pressure of the sample sucked into the pipette tip, and the capacitance sensor is used to detect the liquid level in the sample tube.
[0043] The pressure sensor is installed in the pipeline of the electric sample pump to detect slight pressure changes in the pipeline. When the electric sample pump absorbs the coagulation sample, the coagulation tissue blocks the sample tube. The pressure sensor is used to detect abnormal pressure changes in the pipeline, thereby realizing the detection of the coagulation sample. The capacitance sensor is connected to the pipette tip of the electric sample pump through a wire. During the sample absorption process, the pipette tip contacts the liquid surface in the sample tube. The electric sample pump detects the liquid surface by detecting the change in the capacitance value in the circuit, ensuring the accuracy and stability of the pipetting. Before the electric sample pump absorbs the liquid, it mixes the sample through multiple suction and discharge operations to ensure the uniformity of the sample and the quality of the sample.
[0044] Example 3.
[0045] This embodiment is basically the same as the above embodiment, with the following features:
[0046] See also Figure 3 The rotating clamping robot arm 2 includes a first three-dimensional motion mechanism 23 and a blood collection tube clamping mechanism; the first three-dimensional motion mechanism 23 is used to drive the blood collection tube clamping mechanism to perform three-dimensional motion on the blood collection tube 10, and the blood collection tube transfer and opening module 22 is provided with the blood collection tube clamping mechanism, and the blood collection tube clamping mechanism is used to grab the bottle cap of the blood collection tube 10, so that the grabbed blood collection tube 10 moves between the blood collection tube sample rack 11 and the blood collection tube clamping device 12.
[0047] The first three-dimensional motion mechanism 23 is an XYZ three-dimensional motion mechanism. The blood collection tube clamping mechanism can grab the bottle cap of the blood collection tube 10 to transfer the blood collection tube 10 to the blood collection tube clamping device 12. The blood collection tube clamping device 12 clamps the blood collection tube 10. The clamping mechanism can grab the bottle cap of the blood collection tube 10 and rotate it to open the bottle cap.
[0048] Example 4.
[0049] This embodiment is basically the same as the above embodiment, with the following features:
[0050] See also Figure 1 , Figure 2 The well plate automatic inoculator also includes an equipment cabin 4, a processing flow control device and a supporting mechanism 5. The sample processing platform 1 is arranged at the bottom of the inner cavity of the equipment cabin 4. Both ends of the supporting mechanism 5 are connected to the equipment cabin 4 and are located above the sample processing platform 1. The rotating gripper robot arm 2 and the liquid adding robot arm 3 are installed on the supporting mechanism 5. The processing flow control device is arranged outside the equipment cabin 4. The processing flow control device is connected to the rotating gripper robot arm 2 and the liquid adding robot arm 3 by signal.
[0051] The equipment cabin 4 is a closed structure, which can avoid contamination by impurities in the air. The equipment cabin 4 can fix the support mechanism 5, thereby fixing the rotating gripper robot arm 2 and the liquid adding robot arm 3.
[0052] The processing flow control device includes a program controller and a human-machine interface; the program controller is used for signal control and monitoring of the entire machine; the human-machine interface is composed of a touch control screen, a computer or other human-machine dialogue device and a barcode entry device; the human-machine interface is used to input and output instrument operation parameters, record the instrument operation status and detailed process records of sample processing; the human-machine interface has a module with a network connection function, which monitors the instrument operation status in real time through the network connection, and sends the instrument operation status information and sample processing information to the information management system for recording and analysis; the human-machine interface has a barcode entry function graphic area, which is used to enter the barcode information of the processed sample and the input area for related information such as the reagent batch number used during the operation.
[0053] Example 5.
[0054] This embodiment is basically the same as the above embodiment, with the following features:
[0055] See also Figure 1 , Figure 2 , Figure 8, including an exhaust gas adsorption treatment module 6; the exhaust gas adsorption treatment module 6 is arranged on the top of the equipment cabin 4, and the exhaust gas adsorption treatment module 6 serves as an absorption and transportation device for the gas in the equipment cabin 4; the exhaust gas adsorption treatment module 6 includes an exhaust gas external exhaust fan 61, an exhaust gas adsorbent 62 and a fan outer frame fixing frame 63; the exhaust gas external exhaust fan 61 is installed on the top of the equipment cabin 4 through the fan outer frame fixing frame 63; the exhaust gas adsorbent 62 is arranged below the exhaust gas external exhaust fan 61.
[0056] This embodiment adopts the exhaust gas adsorption treatment module 6, which adds an external exhaust device on the basis of the traditional exhaust gas adsorption, so as to effectively and completely remove the harmful exhaust gas generated in the sample processing process.
[0057] Example 6.
[0058] This embodiment is basically the same as the above embodiment, with the following features:
[0059] See also Figure 2 , Fig. 9 , including an ultraviolet disinfection module 7, which is composed of a multi-tube ultraviolet lamp 71 and is used to disinfect the operating space area in the equipment cabin 4. The ultraviolet lamp 71 is installed on the side wall or under the top of the equipment cabin 4, and the switch of the ultraviolet lamp 71 is controlled by connecting to the control system signal.
[0060] This embodiment adopts a module design of ultraviolet disinfection, which effectively protects the health of operators and the biosafety of the environment.
[0061] Example 7.
[0062] This embodiment is basically the same as the above embodiment, with the following features:
[0063] See also Figure 5 , Figure 6 , Figure 7 The cell culture well plate 15 is of plug-in adjustable type, including a well plate holder 151 and a plurality of well plate slots 152, wherein the well plate slots 152 are clamped on the well plate holder 151. The well plate holder 151 is in a rectangular parallelepiped shape, and the well plate holder 151 is symmetrically provided with bayonet ports 153 on both sides, and each well plate slot 152 is symmetrically provided with a clamping block 154 on both sides, and a plurality of culture grooves 155 are sequentially provided along the extension direction of the well plate slot 152; when the plurality of well plate slots 152 are clamped on the well plate holder 151, the clamping block 154 is clamped in the bayonet port 153.
[0064] The spacing distance of the bayonet 153 is equal to the width of the orifice plate slot 152, and the block 154 is located on the symmetry line of the orifice plate slot 152. In this way, when a row of orifice plate slots 152 are arranged in the orifice plate holder 151, there can be no gap between the multiple orifice plate slots 152.
[0065] The block 154 is in an inverted L shape, and is provided with an insertion portion 1541 and a handle portion 1542. The block 154 is provided at one side of the notch of the orifice plate slot 152 and is flush with the notch of the orifice plate slot 152. The depth of the slot 153 is equal to the length of the insertion portion 1541, and the handle portion 1542 is located outside the slot 153. The handle portion 1542 can facilitate a person to press the orifice plate slot 152 into the orifice plate holder 151 or to pull the orifice plate slot 152 out of the orifice plate holder 151.
[0066] The number of culture slots 155 provided on each well plate slot 152 is the same. The number of well plate slots 152 can be set according to the number of blood collection tubes 10. Multiple well plate slots 152 are arranged side by side and inserted into the well plate holder 151. The number of cell culture slots 155 of the cell culture well plate 15 can be equal to the number of blood collection tubes 10, thereby improving the use efficiency of experimental consumables.
[0067] The embodiments of the utility model are described above in conjunction with the accompanying drawings, but the utility model is not limited to the above embodiments, and various changes can be made according to the purpose of the invention of the utility model. Any changes, modifications, substitutions, combinations or simplifications made according to the spirit and principle of the technical solution of the utility model should be equivalent replacement methods. As long as they meet the purpose of the invention of the utility model and do not deviate from the technical principles and inventive concepts of the utility model, they belong to the protection scope of the utility model.
Claims
1. A well plate type automatic inoculator, characterized in that: It includes a sample processing platform, a rotating gripper robot arm and a liquid adding robot arm; The sample processing platform is provided with a blood collection tube sample rack, a blood collection tube clamping device, a culture medium vessel, a pipette tip placement box and a cell culture well plate; a plurality of blood collection tubes are arranged on the blood collection tube sample rack, and a plurality of pipette tips are arranged on the pipette tip placement box; The rotating clamping claw mechanical arm is arranged above the sample processing platform, and is provided with a blood collection tube automatic barcode entry module and a blood collection tube transfer and cover opening module. The rotating clamping claw mechanical arm can move between the blood collection tube sample rack and the blood collection tube clamping device. The blood collection tube automatic barcode entry module sequentially scans and obtains the barcodes of multiple blood collection tubes on the blood collection tube sample rack, and the blood collection tube transfer and cover opening module clamps and transfers each blood collection tube to the blood collection tube clamping device and opens the bottle cap of the blood collection tube fixed on the blood collection tube clamping device. The liquid-adding robot arm is arranged above the sample processing platform, and can move between the blood collection tube clamping device, the culture medium vessel, the pipette tip placement box and the cell culture well plate. The liquid-adding robot arm absorbs a pipette tip on the pipette tip placement box and absorbs culture medium from the culture medium vessel, and then transfers the absorbed culture medium to the cell culture well plate. The liquid-adding robot arm inserts the pipette tip into the blood collection tube on the blood collection tube clamping device and absorbs the cell sample, and then transfers the cell sample to the cell culture well plate to mix with the culture medium.
2. The well plate type automatic inoculator according to claim 1, characterized in that: The rotating clamping robot arm includes a first three-dimensional motion mechanism and a blood collection tube clamping mechanism; the first three-dimensional motion mechanism is used to drive the blood collection tube clamping mechanism to perform three-dimensional motion on the blood collection tube, and the blood collection tube transfer and opening module is provided with the blood collection tube clamping mechanism, and the blood collection tube clamping mechanism is used to grasp the bottle cap of the blood collection tube, so that the grasped blood collection tube moves between the blood collection tube sample rack and the blood collection tube clamping device.
3. The well plate type automatic inoculator according to claim 1, characterized in that: The cell culture well plate comprises a well plate holder and a plurality of well plate slots, and the well plate slots are mounted on the well plate holder.
4. The well plate type automatic inoculator according to claim 3, characterized in that: The well plate holder is in a rectangular shape, with bayonet ports symmetrically arranged on both sides of the well plate holder, and card blocks symmetrically arranged on both sides of each well plate card slot, and multiple culture slots are arranged in sequence along the extension direction of the well plate card slot; when multiple well plate card slots are arranged on the well plate holder, the card blocks are arranged in the bayonet ports.
5. The well plate type automatic inoculator according to claim 4, characterized in that: The card block is in an inverted L shape and is provided with an insertion portion and a handle portion. The card block is arranged on one side of the slot of the orifice plate and is flush with the slot of the orifice plate. The depth of the slot is equal to the length of the insertion portion, and the handle portion is located on the outside of the slot.
6. The well plate type automatic inoculator according to claim 1, characterized in that: The sample processing platform is also provided with a pipette tip recovery box, which is located on one side of the pipette tip placement box and can receive the pipette tips removed by the liquid adding robot arm.
7. The well plate type automatic inoculator according to claim 1, characterized in that: The liquid-adding robot arm includes a second three-dimensional motion mechanism and a pipetting module; the second three-dimensional motion mechanism drives the pipetting module to move, and the pipetting module is used to automatically remove the pipette tip, transfer the culture medium in the culture medium vessel to the cell culture well plate, mix the cell sample in the blood collection tube on the blood collection tube clamping device, and transfer the cell sample to the cell culture well plate containing the culture medium.
8. The well plate type automatic inoculator according to claim 1, characterized in that: The well plate automatic inoculator also includes an equipment cabin, a processing flow control device and a supporting mechanism. The sample processing platform is arranged at the bottom of the inner cavity of the equipment cabin. Both ends of the supporting mechanism are connected to the equipment cabin and are located above the sample processing platform. The rotating gripper robot arm and the liquid adding robot arm are installed on the supporting mechanism. The processing flow control device is arranged outside the equipment cabin, and the processing flow control device is signal-connected to the rotating gripper robot arm and the liquid adding robot arm.
9. The well plate type automatic inoculator according to claim 8, characterized in that: The orifice plate automatic inoculator also includes a waste gas adsorption treatment module; the waste gas adsorption treatment module is arranged on the top of the equipment cabin, and the waste gas adsorption treatment module serves as an absorption and transportation device for the gas in the equipment cabin; the waste gas adsorption treatment module includes a waste gas external exhaust fan, a waste gas adsorbent and a fan outer frame fixing frame; the waste gas external exhaust fan is installed on the top of the equipment cabin through the fan outer frame fixing frame; the waste gas adsorbent is arranged below the waste gas external exhaust fan.
10. The well plate type automatic inoculator according to claim 8, characterized in that: The well plate automatic inoculator also includes an ultraviolet disinfection module, which is composed of a multi-tube ultraviolet lamp and is used to disinfect the operating space area in the equipment cabin. The ultraviolet lamp is installed on the side wall or under the top of the equipment cabin, and the switch of the ultraviolet lamp is controlled by connecting to the control system signal.
Citation Information
Patent Citations
Automatic cell inoculation instrument
CN218290939U