Protein dialysis device

By introducing the mechanical structure of springs and blocks into the protein dialysis device, combined with the electric heating and stirring function, the problem of difficult protein removal in the prior art is solved, and the rapid removal and efficient dialysis process is achieved, reducing the risk of contamination.

CN222324799UActive Publication Date: 2025-01-10上海逆耳生物科技有限公司
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Patent Information

Application Number
CN202421169319.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-27
Publication Date
2025-01-10
Estimated Expiration
2034-05-27

AI Technical Summary

Technical Problem

In existing protein dialysis devices, the dialysis barrel is located inside the reaction box, making it difficult to remove proteins after dialysis is completed.

Method used

A protein dialysis device including a reaction box, dialysis cylinder, electric heating plate, stirring assembly and lifting rod was designed. Through the mechanical structure of springs and blocks, the lifting rod can quickly remove the dialysis cylinder, combining electric heating and stirring functions. Speed ​​up the dialysis process and reduce dialysate contamination with a cleaning brush.

Benefits of technology

It realizes rapid removal of protein after dialysis, reducing dialysis fluid contamination and improving work efficiency and safety.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of protein dialysis, and discloses a protein dialysis device which comprises a reaction box and a dialysis cylinder arranged in the reaction box, a heating cavity is formed in the reaction box, and an electric heating plate is fixedly installed on the inner wall of the heating cavity formed in the reaction box. The electric heating plate can be communicated with an external power supply through a wire, a stirring assembly is arranged on the reaction box, two fixing blocks are symmetrically and fixedly mounted on the inner side wall of the reaction box, springs are fixedly mounted in the fixing blocks, clamping blocks are fixedly mounted at one ends of the springs, and a connecting cylinder is fixedly mounted at the top of the dialysis cylinder. After dialysis is completed, a worker can push the push rod to move, the push rod can drive the clamping block to move, and the clamping block can extrude the spring and be separated from the clamping groove in the lifting rod, so that the worker can quickly take down the connecting cylinder and the dialysis cylinder through the lifting rod and take out protein in the dialysis cylinder.
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Description

Technical Field

[0001] The utility model relates to the technical field of protein dialysis, in particular to a protein dialysis device. Background Art

[0002] In the process of biological experiments in the laboratory, it is often necessary to perform dialysis, purification and separation experiments on proteins. Among them, the protein dialysis process is to remove small molecules such as salt and impurities in the protein solution and retain the original large molecular protein.

[0003] The utility model with the existing announcement number CN213232080U discloses a protein dialysis device, including a base plate, a reaction box is provided in the middle of the upper surface of the base plate, a dialysis bucket is provided inside the reaction box, and connecting rods are evenly provided on the upper surface of the dialysis bucket. The connecting rods are "U"-shaped rods, and the bottom end of the outer side surface of the connecting rod is slidably installed with the top end of the outer side surface of the fixing rod, and a fixing rod is provided between the left and right sides of the inner cavity of the reaction box.

[0004] In the above technical solution, the inventors found that there are at least the following problems: the dialysis barrel is located inside the reaction box and is slidably connected to the fixed rod on the inner wall of the reaction box through a connecting rod, and the fixed rod is fixedly installed on the reaction box. As a result, after the dialysis is completed, it is inconvenient to take out the protein in the dialysis barrel inside the reaction box. Therefore, how to design a protein dialysis device has become a problem that we currently need to solve. Utility Model Content

[0005] 1. Technical issues to be resolved

[0006] In view of the deficiencies in the prior art, the utility model provides a protein dialysis device to solve the problems mentioned in the above background technology.

[0007] (II) Technical solution

[0008] To achieve the above object, the utility model provides the following technical solution: a protein dialysis device, comprising a reaction box and a dialysis cartridge arranged inside the reaction box, wherein a heating chamber is provided inside the reaction box, an electric heating plate is fixedly installed on the inner wall of the heating chamber provided inside the reaction box, the electric heating plate is electrically connected to an external power supply through a wire, and a stirring assembly is provided on the reaction box;

[0009] Two fixed blocks are symmetrically fixedly installed on the inner wall of the reaction box, a spring is fixedly installed inside the fixed block, a clamping block is fixedly installed at one end of the spring, a connecting cylinder is fixedly installed on the top of the dialysis cartridge, a connecting rod is fixedly installed on the outer surface of the connecting cylinder, a lifting rod is fixedly installed at one end of the connecting rod, a clamping groove matched with the clamping block is provided inside the lifting rod, and placement grooves for placing the lifting rods are provided inside the two fixed blocks.

[0010] Preferably, the stirring assembly includes a motor, which is fixedly connected to the reaction box, and a stirring rod is fixedly installed at the output end of the motor that passes through the reaction box. A cleaning brush is provided on the top of the stirring rod, and an insertion rod is fixedly installed on the bottom of the cleaning brush. The insertion rod is connected to the stirring rod by a fixing bolt.

[0011] Preferably, a foot is fixedly installed on the bottom of the reaction box, and a rubber anti-skid pad is fixedly installed on the bottom of the foot.

[0012] Preferably, an end of the clamping block away from the spring is provided with an inclined surface inclined upward.

[0013] Preferably, a protective shell is fixedly installed on the bottom of the reaction box, and the motor is arranged inside the protective shell.

[0014] Preferably, a push rod is fixedly mounted on the top of the clamping block, a long slide groove is opened on the top of the fixed block, and the push rod passes through the outside of the long slide groove.

[0015] (III) Beneficial effects

[0016] The utility model provides a protein dialysis device, which has the following beneficial effects:

[0017] First: After the dialysis is completed, the staff can push the push rod to move, and the push rod can drive the block to move. The block can squeeze the spring and separate from the slot on the lifting rod, so that the staff can quickly remove the connecting cylinder and the dialysis cartridge through the lifting rod and take out the protein in the dialysis cartridge.

[0018] Second: During dialysis, the staff can add protein solution to the dialysis cylinder, and then add dialysis fluid to the reaction box to the position below the connecting cylinder, start the electric heating plate and the motor, the electric heating plate can heat the dialysis fluid, and the motor can drive the stirring rod to stir the dialysis fluid, thereby speeding up the protein dialysis process.

[0019] Thirdly, when the staff takes out the dialysis cartridge, the cleaning brush on the rotating stirring rod can clean the dialysate attached to the outer surface of the dialysis cartridge, thereby reducing the situation where the dialysate on the outer surface of the dialysis cartridge contaminates the surrounding environment and the staff's clothes when taking out the protein in the dialysis cartridge; when the cleaning brush needs to be cleaned, the staff can separate the insertion rod and the stirring rod from each other by fixing the bolts, so that the staff can remove the cleaning brush for cleaning. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model;

[0021] Figure 2 This is a schematic diagram of the front cross-sectional structure of the utility model;

[0022] Figure 3 For this utility model Figure 2 The enlarged structural diagram at A in the middle;

[0023] Figure 4 This is a schematic diagram of the cleaning brush and the insertion rod structure of the utility model.

[0024] In the figure: 1. reaction box; 2. dialysis cylinder; 3. electric heating plate; 4. stirring assembly; 41. motor; 42. stirring rod; 5. fixing block; 6. spring; 7. clamping block; 8. connecting rod; 9. lifting rod; 10. mounting groove; 11. support foot; 12. inclined plane; 13. protective shell; 14. push rod; 15. connecting cylinder; 16. cleaning brush; 17. plug rod. DETAILED DESCRIPTION

[0025] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0026] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0027] In addition, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of such features. In the description of the present utility model, "multiple" means two or more, unless otherwise clearly and specifically defined.

[0028] like Figure 1-4 As shown, the utility model provides a technical solution: a protein dialysis device, comprising a reaction box 1 and a dialysis cartridge 2 arranged inside the reaction box 1, a support leg 11 is fixedly installed at the bottom of the reaction box 1, the number of the support legs 11 is four, and the four support legs 11 are respectively arranged at the four corners of the bottom of the reaction box 1, and a rubber anti-skid pad is fixedly installed at the bottom of the four support legs 11, and the rubber anti-skid pad can increase the anti-skid performance of the support legs 11.

[0029] Please refer to Figure 2 and Figure 3 Two fixed blocks 5 are symmetrically fixedly installed on the inner wall of the reaction box 1, a spring 6 is fixedly installed inside the fixed block 5, a clamping block 7 is fixedly installed at one end of the spring 6, a connecting cylinder 15 is fixedly installed on the top of the dialysis cylinder 2, and when the dialysis fluid is added into the reaction box 1, the dialysis fluid is located below the connecting cylinder 15. A connecting rod 8 is fixedly installed on the outer surface of the connecting cylinder 15, a lifting rod 9 is fixedly installed at one end of the connecting rod 8, a clamping groove adapted to the clamping block 7 is provided inside the lifting rod 9, and a placement groove 10 for placing the lifting rod 9 is provided inside the two fixed blocks 5.

[0030] Among them, the end of the block 7 away from the spring 6 is provided with an inclined surface 12 inclined upward. When the dialysis cartridge 2 is fixed, the lifting rod 9 on the dialysis cartridge 2 can push the block 7 to move through the inclined surface 12, so that the lifting rod 9 can be quickly connected to the fixed block 5. A push rod 14 is fixedly installed on the top of the block 7. A long chute is provided on the top of the fixed block 5. The push rod 14 runs through the outside of the long chute. The push rod 14 can facilitate the staff to push the block 7 to move.

[0031] Please refer to Figure 1 , Figure 2 and Figure 4A heating chamber is provided inside the reaction box 1. An electric heating plate 3 is fixedly installed on the inner wall of the heating chamber provided inside the reaction box 1. The electric heating plate 3 is electrically connected to an external power source through a wire. A stirring assembly 4 is provided on the reaction box 1. The stirring assembly 4 includes a motor 41. The motor 41 is fixedly connected to the reaction box 1. A stirring rod 42 is fixedly installed at the output end of the motor 41 that passes through the reaction box 1. When in use, the motor 41 can drive the stirring rod 42 to stir the dialysate in the reaction box 1. A cleaning brush 16 is provided on the top of the stirring rod 42. A plug rod 17 is fixedly installed on the bottom of the cleaning brush 16. The plug rod 17 is connected to the stirring rod 42 by a fixing bolt.

[0032] A protective shell 13 is fixedly installed at the bottom of the reaction box 1 , and the motor 41 is arranged inside the protective shell 13 . The protective shell 13 can protect the motor 41 and reduce the possibility of foreign objects touching the protective shell 13 .

[0033] The working process of the utility model is as follows: during dialysis, the staff can add protein solution to the dialysis cartridge 2, and then add dialysis fluid to the reaction box 1 to the position below the connecting cylinder 15, start the electric heating plate 3 and the motor 41, the electric heating plate 3 can heat the dialysis fluid, the motor 41 can drive the stirring rod 42 to stir the dialysis fluid, thereby accelerating the dialysis process of the protein, after the dialysis is completed, the staff can push the push rod 14 to move, the push rod 14 can drive the block 7 to move, the block 7 can squeeze the spring 6 and separate from the groove on the lifting rod 9, so that the staff can quickly remove the connecting cylinder 15 and the dialysis cartridge 2 through the lifting rod 9, and take out the protein in the dialysis cartridge 2;

[0034] When the staff takes out the dialysis cartridge 2 upwards, the cleaning brush 16 on the rotating stirring rod 42 can clean the dialysate attached to the outer surface of the dialysis cartridge 2, thereby reducing the situation where the dialysate on the outer surface of the dialysis cartridge 2 contaminates the surrounding environment and the staff's clothes when taking out the protein in the dialysis cartridge 2; when the cleaning brush 16 needs to be cleaned, the staff can separate the insertion rod 17 and the stirring rod 42 from each other by fixing the bolts, so that the staff can remove the cleaning brush 16 for cleaning.

[0035] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0036] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A protein dialysis device, comprising a reaction box (1) and a dialysis cartridge (2) arranged inside the reaction box (1), characterized in that: A heating chamber is provided inside the reaction box (1), an electric heating plate (3) is fixedly mounted on the inner wall of the heating chamber provided inside the reaction box (1), the electric heating plate (3) is electrically connected to an external power source via a wire, and a stirring assembly (4) is provided on the reaction box (1); Two fixed blocks (5) are symmetrically fixedly installed on the inner wall of the reaction box (1), a spring (6) is fixedly installed inside the fixed block (5), a clamping block (7) is fixedly installed at one end of the spring (6), a connecting cylinder (15) is fixedly installed on the top of the dialysis cartridge (2), a connecting rod (8) is fixedly installed on the outer surface of the connecting cylinder (15), a lifting rod (9) is fixedly installed at one end of the connecting rod (8), a clamping groove matched with the clamping block (7) is provided inside the lifting rod (9), and a placement groove (10) for placing the lifting rod (9) is provided inside the two fixed blocks (5).

2. A protein dialysis device according to claim 1, characterized in that: The stirring assembly (4) comprises a motor (41), the motor (41) is fixedly connected to the reaction box (1), a stirring rod (42) is fixedly installed at the output end of the motor (41) that passes through the reaction box (1), a cleaning brush (16) is arranged on the top of the stirring rod (42), an insertion rod (17) is fixedly installed at the bottom of the cleaning brush (16), and the insertion rod (17) and the stirring rod (42) are connected by a fixing bolt.

3. A protein dialysis device according to claim 1, characterized in that: A support foot (11) is fixedly mounted on the bottom of the reaction box (1), and a rubber anti-slip pad is fixedly mounted on the bottom of the support foot (11).

4. A protein dialysis device according to claim 1, characterized in that: An end of the clamping block (7) away from the spring (6) is provided with an inclined surface (12) inclined upward.

5. A protein dialysis device according to claim 2, characterized in that: A protective shell (13) is fixedly mounted on the bottom of the reaction box (1), and the motor (41) is arranged inside the protective shell (13).

6. A protein dialysis device according to claim 1, characterized in that: A push rod (14) is fixedly mounted on the top of the clamping block (7), a long sliding groove is provided on the top of the fixed block (5), and the push rod (14) penetrates to the outside of the long sliding groove.

Citation Information

Patent Citations

  • Protein dialysis device

    CN213232080U