Protein thermal stability analyzer

Abstract

The utility model relates to the technical field of protein analyzers, and discloses a protein thermal stability analyzer, which comprises a thermal stability analysis box and a protection box which are arranged on a base, the top of the protection box is rotatably connected with a box cover through a hinge, one side of the protection box is fixedly provided with a motor, and the other side of the protection box is fixedly provided with a temperature sensor. The output end, penetrating through the protection box, of the motor is fixedly provided with a two-way screw rod, the end, away from the motor, of the two-way screw rod is rotationally connected with the protection box, and the two ends of the outer surface of the two-way screw rod are in threaded connection with threaded blocks; when a sample in a test tube needs to be heated, a worker can place the test tube into the placing hole in the fixing plate, and the elastic cushion in the placing hole can extrude and fix the test tube under the action of the spring for the test tube with different sizes, so that the condition that the test tube shakes during heating is reduced, the application range of the equipment is expanded, and the test tube is convenient to use. The time waste caused by replacing different test tube fixing plates is avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of protein analyzers, in particular to a protein thermal stability analyzer. Background Art

[0002] The stability of protein is determined not only by its own spatial conformation, such as amino acid composition, hydrogen bonds, disulfide bonds, and hydrophobic bonds, but also by the pH value, salt concentration, and various auxiliary factors in the protein storage or reaction buffer. Whether in the use of industrial enzyme production or in the application of protein drugs in the medical field, people hope that the protein has good stability to improve its efficiency, and protein analyzers are often used to analyze and study proteins.

[0003] When analyzing the thermal stability of proteins, the experimental samples in the test tubes need to be heated. When heating the test tubes, the test tube placement plate can mostly only hold one type of test tube. Test tubes of different sizes may shake or cannot be placed in. Therefore, how to design a protein thermal stability analyzer has become a problem that we currently need to solve. Utility Model Content

[0004] 1. Technical issues to be solved

[0005] In view of the deficiencies of the prior art, the utility model provides a protein thermal stability analyzer to solve the problems mentioned in the above background technology.

[0006] (II) Technical solution

[0007] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a protein thermal stability analyzer, comprising a base and a thermal stability analysis box and a protection box arranged on the base, the top of the protection box is rotatably connected with a box cover through a hinge, a motor is fixedly installed on one side of the protection box, a bidirectional screw is fixedly installed on the output end of the motor that passes through the protection box, the end of the bidirectional screw away from the motor is rotatably connected to the protection box, both ends of the outer surface of the bidirectional screw are threadedly connected with a threaded block, a sliding assembly is arranged at the bottom of the threaded block, a support rod is hinged on the top of the threaded block, a lifting plate is hinged on the end of the support rod away from the threaded block, and a heating box is fixedly installed on the top of the lifting plate;

[0008] A fixing plate is fixedly installed on the inner wall of the heating box, a plurality of placement holes are opened inside the fixing plate, a spring is fixedly installed inside the fixing plate, an elastic pad is fixedly installed at one end of the spring, and the elastic pad is arranged inside the placement hole.

[0009] Preferably, universal wheels are installed at the bottom of the base.

[0010] Preferably, a heating groove is provided inside the heating box, and an electric heating plate is fixedly installed on the inner wall of the heating groove provided inside the heating box, and the electric heating plate is connected to an external power source through a wire.

[0011] Preferably, the sliding assembly comprises a sliding block, one side of the sliding block is fixedly connected to the threaded block, and a sliding groove adapted to the sliding block is provided inside the protection box.

[0012] Preferably, a push rod is fixedly mounted on one side of the protection box, and an anti-slip groove is formed on the outer surface of the push rod.

[0013] Preferably, a protective net is fixedly mounted on the outer surface of the protection box, and the motor is arranged inside the protective net.

[0014] (III) Beneficial effects

[0015] The utility model provides a protein thermal stability analyzer, which has the following beneficial effects:

[0016] First: When it is necessary to heat the sample in the test tube, the staff can put the test tube into the placement hole in the fixing plate. When facing test tubes of different sizes, the elastic pad in the placement hole can squeeze and fix the test tube under the action of the spring, reducing the shaking of the test tube during heating, increasing the application range of the equipment, and avoiding the time wasted in replacing different test tube fixing plates.

[0017] Second: After putting the test tube in, the staff can turn on the motor and the electric heating plate. The electric heating plate can heat the solution in the heating box. The motor can control the movement of the lifting plate. The lifting plate can drive the heating box to move downward to the inside of the protective box, and finally close the box cover to reduce the situation where foreign objects touch the heating box during heating, thereby protecting the test tube samples in the heating box. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model;

[0019] Figure 2 This is a schematic diagram of the cross-sectional structure of the protection box of the utility model;

[0020] Figure 3 For this utility model Figure 2 Enlarged structural diagram at A in the middle.

[0021] In the figure: 1. Thermal stability analysis box; 2. Protection box; 3. Box cover; 4. Motor; 5. Bidirectional lead screw; 6. Threaded block; 7. Sliding assembly; 71. Sliding block; 72. Slide groove; 8. Support rod; 9. Lifting plate; 10. Heating box; 11. Fixed plate; 12. Spring; 13. Elastic pad; 14. Universal wheel; 15. Electric heating plate; 16. Base; 17. Push rod; 18. Protective net. DETAILED DESCRIPTION

[0022] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0023] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0024] In addition, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of such features. In the description of the present utility model, "multiple" means two or more, unless otherwise clearly and specifically defined.

[0025] like Figure 1-3 As shown, the utility model provides a technical solution: a protein thermal stability analyzer, comprising a base 16 and a thermal stability analysis box 1 and a protection box 2 arranged on the base 16, and a universal wheel 14 is installed at the bottom of the base 16, and the number of the universal wheels 14 is four, and the four universal wheels 14 are respectively arranged at the four corners of the bottom of the base 16. A hand push rod 17 is fixedly installed on one side of the protection box 2, and an anti-skid groove is provided on the outer surface of the hand push rod 17, and the anti-skid groove can increase the friction between the hand of the staff and the hand push rod 17, and can reduce the slipping of the hand of the staff when pushing the hand push rod 17.

[0026] Please refer to Figure 1 and Figure 2 The top of the protection box 2 is rotatably connected to a box cover 3 through a hinge, a motor 4 is fixedly installed on one side of the protection box 2, a protection net 18 is fixedly installed on the outer surface of the protection box 2, and the motor 4 is arranged inside the protection net 18. The protection net 18 can protect the motor 4 and reduce the contact of foreign objects with the motor 4.

[0027] Please refer to Figure 1 and Figure 2 A bidirectional screw rod 5 is fixedly installed at the output end of the motor 4 that passes through the protection box 2. The end of the bidirectional screw rod 5 away from the motor 4 is rotatably connected to the protection box 2. Both ends of the outer surface of the bidirectional screw rod 5 are threadedly connected with thread blocks 6. A sliding component 7 is provided at the bottom of the thread block 6. The sliding component 7 includes a slider 71. One side of the slider 71 is fixedly connected to the thread block 6. A sliding groove 72 adapted to the slider 71 is provided inside the protection box 2. The slider 71 and the sliding groove 72 can limit the moving range of the thread block 6 and make the thread block 6 move more smoothly.

[0028] Please refer to Figure 2 and Figure 3 The top of the threaded block 6 is hinged with a support rod 8, and the end of the support rod 8 away from the threaded block 6 is hinged with a lifting plate 9, and a heating box 10 is fixedly installed on the top of the lifting plate 9. A heating groove is provided inside the heating box 10, and an electric heating plate 15 is fixedly installed on the inner wall of the heating groove provided inside the heating box 10. The electric heating plate 15 is connected to an external power supply through a wire, and the electric heating plate 15 can heat the solution inside the heating box 10.

[0029] Among them, a fixing plate 11 is fixedly installed on the inner wall of the heating box 10, and a plurality of placement holes are opened inside the fixing plate 11. A spring 12 is fixedly installed inside the fixing plate 11, and an elastic pad 13 is fixedly installed at one end of the spring 12. The elastic pad 13 is arranged inside the placement hole.

[0030] The working process of the utility model is as follows: when it is necessary to heat the sample in the test tube, the staff can put the test tube into the placement hole in the fixing plate 11. When facing test tubes of different sizes, the elastic pad 13 in the placement hole can squeeze and fix the test tube under the action of the spring 12, thereby reducing the shaking of the test tube during heating, increasing the applicable scope of the equipment, and avoiding the time wasted in replacing different test tube fixing plates 11; after putting in the test tube, the staff can turn on the motor 4 and the electric heating plate 15, and the electric heating plate 15 can heat the solution in the heating box 10, and the motor 4 can drive the bidirectional screw rod 5 to rotate, and the bidirectional screw rod 5 can drive the threaded block 6 to move with the cooperation of the slider 71 and the slide groove 72, and the threaded block 6 can drive the lifting plate 9 to move with the cooperation of the support rod 8, and the lifting plate 9 can drive the heating box 10 to move downward to the inside of the protection box 2, and finally close the box cover 3, thereby reducing the situation where foreign objects touch the heating box 10 during heating, and the test tube samples in the heating box 10 can be protected.

[0031] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0032] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A protein thermal stability analyzer, comprising a base (16) and a thermal stability analysis box (1) and a protection box (2) arranged on the base (16), characterized in that: The top of the protection box (2) is rotatably connected to a box cover (3) via a hinge, a motor (4) is fixedly installed on one side of the protection box (2), a bidirectional screw rod (5) is fixedly installed on the output end of the motor (4) that passes through the protection box (2), the end of the bidirectional screw rod (5) away from the motor (4) is rotatably connected to the protection box (2), both ends of the outer surface of the bidirectional screw rod (5) are threadedly connected to thread blocks (6), a sliding assembly (7) is provided at the bottom of the thread block (6), a support rod (8) is hingedly connected to the top of the thread block (6), and a lifting plate (9) is hingedly connected to the end of the support rod (8) away from the thread block (6), and a heating box (10) is fixedly installed on the top of the lifting plate (9); A fixing plate (11) is fixedly mounted on the inner wall of the heating box (10), a plurality of placement holes are provided inside the fixing plate (11), a spring (12) is fixedly mounted inside the fixing plate (11), an elastic pad (13) is fixedly mounted at one end of the spring (12), and the elastic pad (13) is arranged inside the placement hole.

2. A protein thermal stability analyzer according to claim 1, characterized in that: A universal wheel (14) is installed at the bottom of the base (16).

3. A protein thermal stability analyzer according to claim 1, characterized in that: A heating groove is provided inside the heating box (10), and an electric heating plate (15) is fixedly installed on the inner wall of the heating groove provided inside the heating box (10), and the electric heating plate (15) is connected to an external power source via a wire.

4. A protein thermal stability analyzer according to claim 1, characterized in that: The sliding assembly (7) comprises a sliding block (71), one side of which is fixedly connected to the threaded block (6), and a sliding groove (72) adapted to the sliding block (71) is provided inside the protection box (2).

5. A protein thermal stability analyzer according to claim 1, characterized in that: A push rod (17) is fixedly mounted on one side of the protection box (2), and an anti-slip groove is provided on the outer surface of the push rod (17).

6. A protein thermal stability analyzer according to claim 1, characterized in that: A protective net (18) is fixedly mounted on the outer surface of the protection box (2), and the motor (4) is arranged inside the protective net (18).

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