Integrated collection device for exhaled air condensate

Abstract

The utility model discloses an exhaled air condensate integrated collecting device, which relates to the technical field of exhaled air condensate collection and comprises a refrigerating mechanism, a collecting mechanism and a control mechanism. The condensate collection assembly comprises a collection pipe, a cryopreservation pipe, a gas-liquid separation cover and a gas blowing pipe assembly; the gas-liquid separation cover covers a pipe orifice at the top end of the collecting pipe; the top end pipe orifice of the cryopreservation pipe is detachably connected and communicated with the bottom end pipe orifice of the collection pipe; one end of the air blowing pipe assembly penetrates through the air-liquid separation cover and is inserted into the collecting pipe to input exhaled air; when exhaled air condensate is collected, the collecting pipe is detachably inserted into the cooling inserting hole, so that exhaled air entering the collecting pipe is condensed and liquefied. The exhaled air condensate can be smoothly extracted and transferred, and the risk of being polluted is reduced.

Description

Technical Field

[0001] The utility model relates to the technical field of exhaled breath condensate collection, in particular to an exhaled breath condensate integrated collection device. Background Art

[0002] Exhaled breath condensate examination is a new method for detecting respiratory inflammation. During the breathing process, the exhaled gas contains a large amount of water vapor. The various biochemical molecules contained in these water vapors can indirectly reflect the internal conditions of the respiratory tract. The purpose of examining the respiratory tract can be achieved by observing the conditions of these biochemical molecules. Compared with the traditional sampling and detection methods, the method of collecting exhaled liquid by condensation is simpler. The working principles of existing EBC collectors are mainly divided into water bath method, compressor refrigeration and semiconductor refrigeration. Among them, the advantage of semiconductor refrigeration is that the equipment is smaller in size without generating aerosols.

[0003] A Chinese patent discloses an exhaled breath condensate collection device (authorization announcement number: CN 215135196U), which specifically includes a housing, a condensation block, a semiconductor refrigeration sheet, a heat dissipation device, a condensate collection unit, and a portable handle; the condensate collection unit includes a centrifuge tube, an air blowing pipe, and a gas-liquid separation cover; the gas-liquid separation cover covers the top of the centrifuge tube and is provided with an air outlet and a plug hole; the bottom end of the air blowing pipe passes through the plug hole and is inserted into the centrifuge tube; the condensation block is provided with a cavity that matches the shape of the centrifuge tube; and the top of the housing is provided with a through hole corresponding to the top opening of the cavity. It can be seen that the centrifuge tube is used to collect the exhaled breath condensate in its technical solution, but the exhaled breath condensate collected in the centrifuge tube is not convenient to take out and store, and the collected liquid is easily contaminated when the gas-liquid separation cover is opened for secondary transfer and collection, thereby affecting the detection accuracy.

[0004] Therefore, how to provide an integrated exhaled breath condensate collection device that can smoothly extract and transfer exhaled breath condensate and reduce the risk of contamination is a problem that technical personnel in this field urgently need to solve. Utility Model Content

[0005] In view of this, the utility model proposes an integrated exhaled breath condensate collection device, aiming to solve the technical problem that the exhaled breath condensate collected in the above-mentioned traditional exhaled breath condensate collection device is not convenient to extract and transfer, and is easily contaminated.

[0006] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0007] The utility model provides an integrated collection device for exhaled breath condensate, comprising:

[0008] A refrigeration mechanism, wherein a cooling socket is provided on the refrigeration mechanism;

[0009] A condensate collection assembly, the condensate collection assembly comprising a collection tube, a freezing tube, a gas-liquid separation cover and an air blowing tube assembly; the gas-liquid separation cover is sealed on the top end of the collection tube; the top end of the freezing tube is detachably connected and communicated with the bottom end of the collection tube; one end of the air blowing tube assembly passes through the gas-liquid separation cover and is inserted into the collection tube to input exhaled air; when collecting exhaled air condensate, the collection tube can be detachably inserted into the cooling socket to condense and liquefy the exhaled air entering the collection tube.

[0010] The utility model provides an integrated collection device for exhaled breath condensate. When in use, a collection tube is inserted into a cooling socket, and a refrigeration mechanism is turned on to make the cooling socket in a low-temperature state, thereby reducing the temperature of the collection tube; air is blown into the collection tube through an air blowing tube assembly, and the water vapor with biochemical molecules blown in can condense into droplets when cooled and adhere to the inner wall surface of the collection tube; after the collection is completed, the collection tube is taken out, and the condensate is directly guided into a cryopreservation tube by shaking or vibrating, and the cryopreservation tube is disassembled from the collection tube and refrigerated for storage; the utility model does not require pipetting operations, thereby avoiding cross contamination caused by secondary pipetting of the condensate.

[0011] As a further improvement of the above technical solution, the condensate collection assembly also includes a cryotube sealing cover and a sealing bag for sealing and storing the collection tube, the cryotube, the gas-liquid separation cover, the blowing tube assembly and the cryotube sealing cover;

[0012] The cryogenic tube sealing cover can detachably seal the top tube opening of the cryogenic tube.

[0013] The beneficial effects of the above technical solution are: the cryogenic tube sealing cap is used to timely seal the tube mouth of the cryogenic tube that collects and stores exhaled breath condensate; the sealing bag is used to seal and preserve the collection tube, cryogenic tube, gas-liquid separation cap, blowing tube assembly and cryogenic tube sealing cap that have been sterilized and disinfected, and is convenient for storage and transportation.

[0014] As a further improvement of the above technical solution, the gas-liquid separation cover is provided with an air blowing pipe jack and an exhaust hole; the air blowing pipe assembly includes an air blowing pipe and a blowing nozzle connected to one end of the air blowing pipe; the other end of the air blowing pipe passes through the air blowing pipe jack and is inserted into the collection tube.

[0015] The beneficial effects of the above technical solution are: the air tube insertion hole can seal and fix the inserted air tube; the mouthpiece can prevent saliva from entering the air tube when blowing; the exhaust hole is used to discharge excess gas to ensure the smooth flow of exhaled air in the collection tube.

[0016] As a further improvement of the above technical solution, filter cotton is installed in the exhaust hole; the air outlet of the air blowing pipe is close to the inner wall surface of the collection pipe, and its air outlet direction is tangent to the corresponding inner wall surface of the collection pipe.

[0017] The beneficial effects of the above technical solution are: the filter cotton can filter the aerosol in the exhaled breath to avoid the pollution of the aerosol to the environment; the air outlet of the blowing tube is close to the inner wall of the collection tube and its air outlet direction is tangent to the inner wall of the corresponding collection tube, so that the blown-in exhaled air can form a spiral airflow and flow along the inner wall of the collection tube, prolonging the contact time between the exhaled air and the collection tube wall, increasing the condensation effect, and at the same time, the condensate on the collection tube wall can be blown off, reducing the formation of liquid film and accelerating the collection efficiency.

[0018] As a further improvement of the above technical solution, the refrigeration mechanism includes a shell, a condensation block, a semiconductor refrigeration sheet, a radiator, a cooling fan, a temperature sensor and a temperature controller;

[0019] The condensation block is fixedly installed inside the shell, the top of which is provided with the cooling jack, and the side wall of which is provided with a sensor mounting hole; the cooling surface of the semiconductor refrigeration sheet is fixedly attached to a wall surface of one side of the condensation block; the radiator is located on a side of the semiconductor refrigeration sheet away from the condensation block and is fixedly attached to the heat dissipation surface of the semiconductor refrigeration sheet; the detection end of the temperature sensor is inserted into the sensor mounting hole;

[0020] A through hole is provided at the top of the shell corresponding to the cooling socket; ventilation holes are provided at two opposite side walls of the shell corresponding to the radiator, so as to form a heat dissipation duct between two corresponding ventilation holes inside the shell; the heat dissipation fan is fixedly installed inside the shell and corresponds to between the radiator and one of the ventilation holes;

[0021] The temperature controller is electrically connected to the semiconductor refrigeration sheet, the heat dissipation fan and the temperature sensor.

[0022] The beneficial effects of the above technical solution are: the semiconductor refrigeration plate is used to cool the condensation block; the radiator is used to quickly conduct the heat from the heat dissipation surface of the semiconductor refrigeration plate, the cooling fan can discharge the heat emitted by the radiator to the outside of the shell, the temperature sensor is used to detect the temperature of the condensation block in real time; the thermostat is used to adjust the temperature of the condensation block.

[0023] As a further improvement of the above technical solution, a heat insulation layer is provided on the outer surface of the condensation block.

[0024] The beneficial effect of the above technical solution is that the function of the heat insulation layer is to reduce the heat transfer between the condensation block and the outside world, and reduce the influence of the external environment temperature on the collection effect.

[0025] As a further improvement of the above technical solution, a partition is provided in the shell at the bottom corresponding to the radiator and the cooling fan to limit the cooling air duct to the area above the partition; and a portable handle is installed in the middle of the top surface of the shell.

[0026] The beneficial effects of the above technical solution are: the partition serves to isolate and seal the excess space below the radiator, thereby reducing the heat dissipation air duct space inside the shell and improving the heat dissipation efficiency; the device is designed with a portable handle for easy transportation and carrying.

[0027] As a further improvement of the above technical solution, there are two cooling fans, both of which are fixedly installed inside the shell and arranged on both sides of the radiator respectively; and the ventilation opening is a louver window.

[0028] The beneficial effect of the above technical solution is that the cooling fans are arranged on both sides of the corresponding radiator to further improve the ventilation and cooling effect. The vent is designed as a shutter structure, which is used to expand the cross-sectional area on the basis of ensuring the structural strength of the air inlet and outlet of the shell; the shutter window, the cooling fan, and the radiator are all arranged in sequence in the same direction. When the wind direction of the cooling fans on both sides is consistent, the airflow can enter the cooling air duct from the shutter window on one side, pass through the radiator, and then be discharged from the shutter window on the other side.

[0029] As a further improvement of the above technical solution, it also includes an ejection mechanism installed in the shell; the cooling socket is a through hole; the collection tube is inserted into the hole at one end of the cooling socket and is positioned in the cooling socket by interference fit, and the bottom end of the freezing tube is located outside the cooling socket, and the ejection end of the ejection mechanism can abut the bottom end of the freezing tube to drive it to move axially along the cooling socket and drive the collection tube to escape from the cooling socket.

[0030] The beneficial effects of the above technical solution are: the collection tube and the cooling socket are positioned by interference fit, the fit is tight and the heat conduction effect is good; the ejection end of the ejection mechanism abuts against the bottom end of the cryopreservation tube to eject the collection tube from the cooling socket, thereby realizing quick disassembly and assembly of the collection tube and improving detection efficiency.

[0031] As a further improvement of the above technical solution, the ejection mechanism includes a lever and a pull-back spring; the lever is hinged at the bottom of the condensation block, one end of the lever is an ejection end arranged corresponding to the bottom end of the cryogenic tube, the other end of the lever is a pressing end, and an operating port is provided on the outer wall of the shell corresponding to the pressing end; pressing the pressing end can drive the lever to swing, so that the ejection end abuts against and drives the cryogenic tube;

[0032] One end of the pull-back spring is fixedly installed inside the housing, and the other end is fixedly connected to the pressing end so as to pull the lever in the pressed state back and reset.

[0033] The beneficial effect of the above technical solution is that when taking out the collection tube, you can insert your finger into the operating port and press the pressing end to make the lever swing, thereby driving the ejection end to abut against the freezing tube, thereby ejecting the collection tube from the cooling socket; the technical effect of convenient operation, simple structure and low production cost is achieved.

[0034] It can be seen from the above technical solutions that, compared with the prior art, the utility model discloses an integrated collection device for exhaled breath condensate, which has the following advantages and beneficial effects:

[0035] 1. The supporting consumables (collection tube, cryopreservation tube, gas-liquid separation cover, air blowing tube assembly and cryopreservation tube sealing cover) of the utility model realize an integrated packaging design. A cryopreservation tube is added at the lower end of the collection tube, and the condensate directly enters the cryopreservation tube, which makes the collection of the condensate more convenient, avoids cross contamination caused by the pipetting of the condensate, simplifies the collection operation steps, and improves the efficiency of equipment use.

[0036] 2. The condensing block of the utility model adopts high thermal conductivity material and wraps a heat insulation layer on the outer surface, so that the equipment can be cooled evenly and quickly, and is less affected by the external ambient temperature; the condensing temperature of the condensing block can be automatically adjusted by a thermostat, and the cooling socket of the condensing block and the collection tube are designed to be an interference fit connection, which maximizes the thermal conductivity efficiency, reduces the heat capacity of the condensing block, and thus improves the collection efficiency.

[0037] 3. The utility model adopts semiconductor refrigeration to reduce the space of the refrigeration mechanism, which is conducive to the portability of the collection device; the collection tube uses the principle of lever, and the pressing end is pressed by hand to push the collection tube out of the condensation block, which is convenient for taking. The shell is designed as a shutter structure at the air inlet and outlet of the cooling fan, and the cooling air duct is centered on the center of the heat sink, which is convenient for heat dissipation and improves the cooling efficiency of the equipment; and multiple cooling fans cool the radiator in the same direction, and a partition is added inside the shell to seal and isolate the excess space below the radiator, so that the internal cooling air duct space becomes smaller, thereby improving the cooling efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0038] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings in the following description are only embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on the provided drawings without paying creative work.

[0039] Figure 1 A schematic diagram of the internal structure of an integrated exhaled breath condensate collection device according to the utility model;

[0040] Figure 2 A schematic diagram of the installation state of a collection tube of an integrated collection device for exhaled breath condensate according to the utility model;

[0041] Figure 3 A schematic diagram of a state in which a collection tube of an integrated collection device for exhaled breath condensate is pushed out of the utility model;

[0042] Figure 4 A schematic diagram of the packaging state of the consumables of the integrated exhaled breath condensate collection device of the utility model;

[0043] Figure 5 A schematic diagram of the unfolded state of the air blowing tube assembly of the integrated collection device for exhaled breath condensate according to the utility model;

[0044] Figure 6 A schematic diagram of the structure of a gas-liquid separation cover of an integrated collection device for exhaled breath condensate according to the utility model;

[0045] Figure 7 A schematic diagram of the installation state of the air blowing tube of the integrated collection device for exhaled air condensate of the utility model;

[0046] Figure 8 A schematic diagram of the structure of a condensate block of an integrated collection device for exhaled breath condensate according to the utility model;

[0047] Fig. 9 A schematic diagram of the bottom structure of a condensate block of an integrated collection device for exhaled breath condensate according to the utility model;

[0048] Fig.10 A schematic diagram of the external structure of an integrated exhaled breath condensate collection device according to the utility model;

[0049] Fig.11 A schematic diagram of the external structure of the utility model of an integrated collection device for exhaled breath condensate from another perspective;

[0050] In the figure: 1, refrigeration mechanism; 11, shell; 111, through hole; 112, vent; 113, partition; 114, portable handle; 115, operation port; 12, condensation block; 121, cooling jack; 122, sensor mounting hole; 123, thermal insulation layer; 124, semiconductor refrigeration plate mounting hole; 125, lever mounting groove; 126, fixed shaft mounting hole; 127, condensation block fixed mounting hole; 13, semiconductor refrigeration plate; 14, radiator; 15, Cooling fan; 16. Thermostat; 2. Condensate collection assembly; 21. Collection tube; 22. Cryogenic tube; 23. Gas-liquid separation cover; 231. Air blowing tube jack; 232. Exhaust hole; 2321. Filter cotton; 24. Air blowing tube assembly; 241. Air blowing tube; 242. Blowing nozzle; 243. Spiral airflow; 25. Cryogenic tube sealing cover; 26. Sealing bag; 3. Ejection mechanism; 31. Lever; 311. Ejection end; 312. Pressing end; 32. Pull-back spring. DETAILED DESCRIPTION

[0051] The embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, and should not be construed as limiting the present invention.

[0052] In the description of the present invention, it should be understood that the terms "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0053] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present utility model, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0054] In the present invention, unless otherwise clearly specified and limited, the terms "install", "connect", "connect", "fix" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0055] like Figures 1 to 11 As shown, an integrated exhaled breath condensate collection device comprises:

[0056] A refrigeration mechanism 1, wherein a cooling socket 121 is provided on the refrigeration mechanism 1;

[0057] The condensate collection assembly 2 includes a collection tube 21, a cryopreservation tube 22, a gas-liquid separation cover 23 and an air blowing tube assembly 24; the gas-liquid separation cover 23 is sealed on the top end of the collection tube 21; the top end of the cryopreservation tube 22 is threadedly connected and communicated with the bottom end of the collection tube 21; one end of the air blowing tube assembly 24 passes through the gas-liquid separation cover 23 and is inserted into the collection tube 21 to input the exhaled air; when collecting the exhaled air condensate, the collection tube 21 can be detachably inserted into the cooling socket 121 to condense and liquefy the exhaled air entering the collection tube 21.

[0058] The present embodiment is an integrated collection device for exhaled breath condensate. When in use, the collection tube 21 is inserted into the cooling socket 121, and the refrigeration mechanism 1 is turned on to make the cooling socket 121 in a low-temperature state, thereby reducing the temperature of the collection tube 21; air is blown into the collection tube 21 through the blowing tube assembly 24, and the water vapor with biochemical molecules blown in can condense into droplets when cooled and adhere to the inner wall surface of the collection tube 21; after the collection is completed, the collection tube 21 is taken out, and the condensate is directly guided into the freezing tube 22 by shaking or vibrating, and the freezing tube 22 is removed from the collection tube 21 and refrigerated. The utility model does not require pipetting operations, thereby avoiding cross contamination caused by secondary pipetting of the condensate.

[0059] In some embodiments, the condensate collection assembly 2 also includes a cryogenic tube sealing cover 25 and a sealing bag 26 for sealing and preserving the collection tube 21, the cryogenic tube 22, the gas-liquid separation cover 23, the blowing tube assembly 24 and the cryogenic tube sealing cover 25; the cryogenic tube sealing cover 25 is threadedly connected and sealed on the top tube opening of the cryogenic tube 22.

[0060] The cryotube sealing cap 25 is used to timely seal the mouth of the cryotube 22 that collects and stores exhaled breath condensate; the sealing bag 26 is used to seal and preserve the collection tube 21, cryotube 22, gas-liquid separation cap 23, blowing tube assembly 24 and cryotube sealing cap 25 that have been sterilized and disinfected, and is convenient for storage and transportation.

[0061] In some embodiments, the gas-liquid separation cover 23 is provided with an air blowing pipe jack 231 and an exhaust hole 232; the air blowing pipe assembly 24 includes an air blowing pipe 241 and a blowing nozzle 242 connected to one end of the air blowing pipe 241; the other end of the air blowing pipe 241 passes through the air blowing pipe jack 231 and is inserted into the collection tube 21.

[0062] The inner wall of the air tube insertion hole 231 is sealed to the outer wall of the air tube 241 to seal and fix the inserted air tube 241; the mouthpiece 242 can prevent saliva from entering the air tube when blowing; the exhaust hole 232 is used to discharge excess gas to ensure the smooth flow of exhaled air in the collection tube 21.

[0063] In some embodiments, a filter cotton 2321 is installed in the exhaust hole 232 ; the air outlet of the air blowing pipe 241 is close to the inner wall surface of the collection tube 21 , and its air outlet direction is tangent to the inner wall surface of the corresponding collection tube 21 .

[0064] The filter cotton 2321 can filter aerosols in the exhaled air to prevent aerosols from polluting the environment; the air outlet of the blowing tube 241 is close to the inner wall of the collection tube 21 and its air outlet direction is tangent to the inner wall of the corresponding collection tube 21, so that the blown-in exhaled air can form a spiral airflow 243 and flow along the inner wall of the collection tube 21, thereby extending the contact time between the exhaled air and the collection tube wall, increasing the condensation effect, and at the same time blowing off the condensate on the collection tube wall, reducing the formation of liquid film, and accelerating the collection efficiency.

[0065] In some embodiments, the refrigeration mechanism 1 includes a housing 11, a condensing block 12, a semiconductor refrigeration sheet 13, a radiator 14, a cooling fan 15, a temperature sensor and a temperature controller 16;

[0066] The condensation block 12 is fixedly installed at the bottom of the shell 11 with bolts, and a cooling socket 121 is provided at its top, and a sensor mounting hole 122 and a semiconductor refrigeration plate mounting hole 124 are provided on its side wall; the cooling surface of the semiconductor refrigeration plate 13 is attached to one side wall of the condensation block 12 and is fixed to the bolts through the semiconductor refrigeration plate mounting hole 124; the radiator 14 is located on the side of the semiconductor refrigeration plate 13 away from the condensation block 12 and is attached to the heat dissipation surface of the semiconductor refrigeration plate 13 and fixed by bolts; after thermal grease is applied on both sides of the semiconductor refrigeration plate 13, the cooling surface is tightly attached to the condensation block, and the heat dissipation surface is tightly attached to the radiator, so as to cool the condensation block. The detection end of the temperature sensor is adapted to be inserted into the sensor mounting hole 122;

[0067] A through hole 111 is provided at the top of the housing 11 corresponding to the cooling socket 121; ventilation holes 112 are provided at two opposite side walls of the housing 11 corresponding to the radiator 14, so as to form a heat dissipation duct between the two corresponding ventilation holes 112 inside the housing 11; a heat dissipation fan 15 is fixedly installed inside the housing 11 and between the corresponding radiator 14 and one of the ventilation holes 112;

[0068] The temperature controller 16 is electrically connected to the semiconductor cooling sheet 13 , the cooling fan 15 and the temperature sensor.

[0069] The semiconductor refrigeration plate 13 is used to cool the condensation block 12; the radiator 14 is used to quickly conduct the heat from the heat dissipation surface of the semiconductor refrigeration plate 13, and the cooling fan 15 can discharge the heat emitted by the radiator 14 to the outside of the shell 11. The temperature sensor is used to detect the temperature of the condensation block 12 in real time; the thermostat 16 is used to adjust the temperature of the condensation block 12.

[0070] In some embodiments, a heat insulation layer 123 is disposed on the outer surface of the condensation block 12 .

[0071] The function of the heat insulation layer 123 is to reduce the heat transfer between the condensation block 12 and the outside world, and reduce the influence of the external environment temperature on the collection effect.

[0072] Specifically, the heat insulation layer 123 is a heat insulation foam with a heat preservation function, which is evenly pasted and wrapped on the outer surface of the condensation block.

[0073] In some embodiments, a partition 113 is provided at the bottom of the shell 11 corresponding to the radiator 14 and the cooling fan 15 to limit the cooling air duct to the area above the corresponding partition 113; a portable handle 114 is installed in the middle of the top surface of the shell 11.

[0074] The partition 113 serves to isolate and seal the redundant space below the radiator, thereby reducing the space of the heat dissipation air duct inside the shell and improving the heat dissipation efficiency; the device is designed with a portable handle for easy transportation and carrying.

[0075] In some embodiments, there are two cooling fans 15 , both of which are fixedly installed inside the housing 11 and arranged on both sides of the radiator 14 ; the vents 112 are louvered windows.

[0076] The cooling fans 15 are arranged on both sides of the corresponding radiator 14 to further improve the ventilation and heat dissipation effect. The vent 112 is designed as a shutter structure, which is used to expand the cross-sectional area on the basis of ensuring the structural strength of the air inlet and outlet of the shell; the shutter window, the cooling fan, and the radiator are all arranged in sequence in the same direction. When the wind directions of the cooling fans on both sides are consistent, the airflow can enter the heat dissipation duct from the shutter window on one side, pass through the radiator, and then be discharged from the shutter window on the other side.

[0077] In some embodiments, it also includes an ejection mechanism 3 installed in the shell 11; the cooling socket 121 is a through hole that passes through the top end and the bottom end of the condensation block 12; the collection tube 21 is inserted into the hole at one end of the cooling socket 121 and is positioned in the cooling socket 121 by interference fit, and the bottom end of the cryopreservation tube 22 is located outside the cooling socket 121, and the ejection end of the ejection mechanism 3 can abut the bottom end of the cryopreservation tube 22 to drive it to move axially along the cooling socket 121 and drive the collection tube 21 to disengage from the cooling socket 121.

[0078] The collection tube 21 and the cooling socket 121 are positioned by interference fit, and the fit is tight and the heat conduction effect is good; the ejection end of the ejection mechanism 3 abuts against the bottom end of the cryopreservation tube 22 to eject the collection tube 21 from the cooling socket 121, thereby realizing quick disassembly and assembly of the collection tube 21 and improving detection efficiency.

[0079] In some embodiments, the ejection mechanism 3 includes a lever 31 and a pull-back spring 32; a lever mounting groove 125 is provided at the bottom end of the condensation block 12 corresponding to the cooling socket 121, the lever mounting groove 125 is an open groove and is connected to the cooling socket 121, a fixed shaft mounting hole 126 is provided on the side wall opposite to the lever mounting groove 125, the lever 31 is hinged on the inner wall of the lever mounting groove 125 through a fixed shaft passing through the fixed shaft mounting hole 126, one end of the lever 31 is an ejection end 311 arranged at the bottom end of the cryopreservation tube 22, the other end of the lever 31 is a pressing end 312, and an operating port 115 is provided on the outer wall of the shell 11 corresponding to the pressing end 312; pressing the pressing end 312 can drive the lever 31 to swing, so that the ejection end 311 abuts against the driving cryopreservation tube 22;

[0080] The upper end of the pull-back spring 32 is fixedly mounted on the upper inner portion of the housing 11 , and the lower end is fixedly connected to the pressing end 312 to pull the lever 31 in the pressed state back to reset.

[0081] When taking out the collection tube 21, one can insert a finger into the operating port 115 and press the pressing end 312 to make the lever 31 swing around the fixed axis, thereby driving the ejection end 311 to abut against the bottom end of the cryopreservation tube 22, thereby ejecting the collection tube 21 from the cooling socket 121; the technical effect of convenient operation, simple structure and low manufacturing cost is achieved.

[0082] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the utility model. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine different embodiments or examples described in this specification.

[0083] Although the embodiments of the present invention have been shown and described above, it can be understood that the above embodiments are exemplary and cannot be understood as limitations of the present invention. Ordinary technicians in the field can change, modify, replace and modify the above embodiments within the scope of the present invention.

Claims

1. An integrated exhaled breath condensate collection device, characterized in that: include: A refrigeration mechanism (1), wherein a cooling plug hole (121) is provided on the refrigeration mechanism (1); A condensate collection assembly (2), the condensate collection assembly (2) comprising a collection tube (21), a cryopreservation tube (22), a gas-liquid separation cover (23) and an air blowing pipe assembly (24); the gas-liquid separation cover (23) is sealed at the top end of the collection tube (21); the top end of the cryopreservation tube (22) is detachably connected and communicated with the bottom end of the collection tube (21); one end of the air blowing pipe assembly (24) passes through the gas-liquid separation cover (23) and is inserted into the collection tube (21) to input exhaled air; when collecting exhaled air condensate, the collection tube (21) is detachably inserted into a cooling socket (121) to condense and liquefy the exhaled air entering the collection tube (21).

2. The exhaled breath condensate integrated collection device according to claim 1, characterized in that: The condensate collection assembly (2) further comprises a cryotube sealing cover (25) and a sealing bag (26) for sealing and storing the collection tube (21), the cryotube (22), the gas-liquid separation cover (23), the air blowing tube assembly (24) and the cryotube sealing cover (25); The cryotube sealing cover (25) can be detachably sealed to cover the top tube opening of the cryotube (22).

3. The exhaled breath condensate integrated collection device according to claim 1, characterized in that: The gas-liquid separation cover (23) is provided with an air blowing pipe insertion hole (231) and an exhaust hole (232); the air blowing pipe assembly (24) comprises an air blowing pipe (241) and a blowing nozzle (242) connected to one end of the air blowing pipe (241); the other end of the air blowing pipe (241) passes through the air blowing pipe insertion hole (231) and is inserted into the collection pipe (21).

4. The exhaled breath condensate integrated collection device according to claim 3, characterized in that: The exhaust hole (232) contains filter cotton (2321); the air outlet of the air blowing pipe (241) is close to the inner wall surface of the collection pipe (21), and its air outlet direction is tangent to the inner wall surface of the corresponding collection pipe (21).

5. The exhaled breath condensate integrated collection device according to claim 1, characterized in that: The refrigeration mechanism (1) comprises a housing (11), a condensation block (12), a semiconductor refrigeration sheet (13), a radiator (14), a cooling fan (15), a temperature sensor and a temperature controller (16); The condensation block (12) is fixedly installed inside the shell (11), and the cooling plug hole (121) is opened on the top of the condensation block, and the sensor installation hole (122) is opened on the side wall; the cooling surface of the semiconductor refrigeration plate (13) is fixedly attached to the wall surface of one side of the condensation block (12); the heat sink (14) is located on the side of the semiconductor refrigeration plate (13) away from the condensation block (12) and is fixedly attached to the heat dissipation surface of the semiconductor refrigeration plate (13); the detection end of the temperature sensor is inserted into the sensor installation hole (122); A through hole (111) is provided at the top of the shell (11) corresponding to the cooling plug hole (121); ventilation holes (112) are provided on two opposite side walls of the shell (11) corresponding to the radiator (14) to form a heat dissipation duct between the two corresponding ventilation holes (112) inside the shell (11); the heat dissipation fan (15) is fixedly installed inside the shell (11) and between the radiator (14) and one of the ventilation holes (112); The temperature controller (16) is electrically connected to the semiconductor cooling sheet (13), the cooling fan (15) and the temperature sensor.

6. The exhaled breath condensate integrated collection device according to claim 5, characterized in that: The outer surface of the condensation block (12) is provided with a heat insulation layer (123).

7. The exhaled breath condensate integrated collection device according to claim 5, characterized in that: A partition (113) is provided at the bottom of the shell (11) corresponding to the radiator (14) and the cooling fan (15) so as to limit the cooling air duct to the area above the partition (113); and a portable handle (114) is installed in the middle of the top surface of the shell (11).

8. The exhaled breath condensate integrated collection device according to claim 5, characterized in that: There are two cooling fans (15), and the two cooling fans (15) are fixedly installed inside the housing (11) and are arranged corresponding to two sides of the radiator (14) respectively; the ventilation opening (112) is a shutter window.

9. The exhaled breath condensate integrated collection device according to claim 5, characterized in that: It also includes an ejection mechanism (3) installed in the shell (11); the cooling socket (121) is a through hole; the collection tube (21) is inserted into the hole at one end of the cooling socket (121) and is positioned in the cooling socket (121) by interference fit, and the bottom end of the freezing tube (22) is located outside the cooling socket (121); the ejection end of the ejection mechanism (3) can abut the bottom end of the freezing tube (22) to drive it to move axially along the cooling socket (121) and drive the collection tube (21) to escape from the cooling socket (121).

10. The exhaled breath condensate integrated collection device according to claim 9, characterized in that: The ejection mechanism (3) comprises a lever (31) and a pull-back spring (32); the lever (31) is hinged at the bottom of the condensation block (12); one end of the lever (31) is an ejection end (311) arranged corresponding to the bottom end of the cryogenic tube (22); the other end of the lever (31) is a pressing end (312); an operating port (115) is provided on the outer wall of the shell (11) corresponding to the pressing end (312); pressing the pressing end (312) can drive the lever (31) to swing, so that the ejection end (311) abuts against and drives the cryogenic tube (22); One end of the pull-back spring (32) is fixedly mounted inside the housing (11), and the other end is fixedly connected to the pressing end (312) so as to pull the lever (31) in the pressed state back to reset.

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