Liquid preparation tank for preparing liquid medicine
By using the decomposition parts of the liquid dispensing tank in the production of lyophilized powder injection, the problem of the raw material liquid not being removed is solved, and the quality of the drug and the removal efficiency are improved.
Patent Information
- Application Number
- CN202420979344.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-08
- Publication Date
- 2025-02-11
- Estimated Expiration
- 2034-05-08
AI Technical Summary
During the production process of lyophilized powder injection, the raw material liquid is not treated with impurities, resulting in excess macromolecules in the solution, affecting the quality of the drug.
A liquid dispensing tank is designed, including a tank body, agitating parts and impurity removal parts. The decomposition removal component includes a rotating and sliding up and down mounting frame, decomposition frame and decomposition net. The decomposition removal component is driven to rotate and jump through the transmission component to improve the decomposition removal efficiency.
By setting up decomposition components in the liquid dispensing tank, the excess macromolecules in the solution are effectively removed, improving the stability of the quality of the drug and the decompression efficiency.
Smart Images

Figure CN222446340U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of medicine production equipment, in particular to a liquid preparation tank used for preparing medicine liquid. Background Art
[0002] Lyophilized powder injection is made from protease as the active ingredient through a freeze-drying process.
[0003] During the production process of freeze-dried powder injection, the protease raw material needs to be dissolved into a solution. In the prior art, the raw material liquid is not treated for impurities during the production process, resulting in the presence of excess macromolecules in the solution, affecting the quality of the final drug. In order to solve this technical problem, a liquid preparation tank for preparing the drug solution is proposed. Utility Model Content
[0004] The purpose of the utility model is to provide a liquid preparation tank for preparing liquid medicine, so as to solve the problems raised in the above background technology.
[0005] In order to achieve the above purpose, the utility model provides the following technical solutions:
[0006] A liquid preparation tank for preparing liquid medicine, comprising: a tank body, wherein the tank body is provided with a feeding port and a discharging port;
[0007] A stirring component is rotatably arranged inside the tank body;
[0008] The impurity removal component is arranged below the feeding port; the impurity removal component comprises an installation frame which is arranged inside and rotates and slides up and down, the installation frame is provided with an impurity removal frame inside, and the impurity removal frame is provided with an impurity removal net inside;
[0009] And, the transmission component arranged between the stirring component and the impurity removing component is used to drive the impurity removing component to rotate and jump when adding materials and removing impurities.
[0010] As a further solution of the utility model: the stirring component includes a stirring shaft rotatably mounted on the tank body and a plurality of stirring blades arranged in an array on the stirring shaft, and the stirring blades are welded and arranged on the stirring shaft.
[0011] As a further solution of the utility model: at least two elastic telescopic rods are arranged at the bottom of the installation frame, the elastic telescopic rods are fixedly mounted on the installation ring, the installation ring is rotatably arranged on the support seat, and the support seat is fixedly mounted inside the tank body.
[0012] As a further solution of the utility model: the transmission component includes a transmission telescopic rod symmetrically arranged on the stirring shaft and a matching block fixedly installed on the bottom of the installation frame, and a plurality of drive grooves are arranged in a circular array on the matching block, and the transmission telescopic rod is used to be inserted into the drive groove when the installation frame is lowered.
[0013] As a further solution of the utility model: at least two interference rods are arranged in an array outside the installation frame, a support ring is sleeved on the outside of the installation frame, and the support ring is fixedly installed inside the tank body; a plurality of interference protrusions are arranged in an array on the support ring, and the interference protrusions are arranged on the trajectory of the interference rods.
[0014] As a further solution of the utility model: the impurity removal frame is slidably arranged inside the installation frame.
[0015] As a further solution of the utility model: a plurality of guide sliding blocks are arranged on the outer side of the impurity removal frame, and the guide sliding blocks are slidably arranged in the slide grooves inside the installation frame.
[0016] As a further solution of the utility model: the impurity removal net is a barrel-shaped structure with an opening on the top.
[0017] As a further solution of the utility model: a pressure ring is installed at the top opening of the impurity removal frame to fix the bottom of the impurity removal net.
[0018] Compared with the prior art, the utility model has the following beneficial effects: protease raw materials are added to the interior of the tank body through the feeding port, the impurity removal component removes impurities from the protease raw materials, and at the same time the stirring component rotates to drive the impurity removal component to rotate and jump, thereby improving the impurity removal efficiency. The utility model solves the problem of the need to remove impurities from the raw materials by providing the impurity removal component, and at the same time the impurity removal component can rotate and jump, thereby improving the impurity removal efficiency. BRIEF DESCRIPTION OF THE DRAWINGS
[0019] Figure 1 It is a schematic diagram of the structure of a liquid preparation tank used for preparing liquid medicine.
[0020] Figure 2 for Figure 1 Enlarged view of point A in the middle.
[0021] Figure 3 This is a schematic diagram of the structure of the matching block in the liquid preparation tank used to prepare the medicine solution.
[0022] Figure 4 The figure is a schematic diagram of the structure of the installation frame in the liquid preparation tank used for preparing the liquid medicine.
[0023] In the figure: 10-tank body, 11-lower tank body, 12-upper tank body, 20-stirring component, 101-feeding port, 102-discharge port, 201-stirring shaft, 202-driving motor, 203-stirring blade, 204-transmission telescopic rod, 30-impurity removal component, 301-installation frame, 302-impurity removal frame, 303-pressing ring, 304-impurity removal net, 305-matching block, 306-telescopic rod, 307-installation ring, 308-support seat, 3011-slide groove, 3012-resistance rod, 3013-support ring, resistance protrusion-3014, 3021-guide slider, 3051-drive groove. DETAILED DESCRIPTION
[0024] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0025] Example 1
[0026] See also Figures 1 to 4 In Example 1 of the utility model, a structural diagram of a liquid preparation tank for preparing liquid medicine provided by the utility model embodiment includes: a tank body 10, on which a feeding port 101 and a discharging port 102 are provided; a stirring component 20, which is rotatably arranged inside the tank body 10; a de-dusting component 30, which is arranged below the feeding port 101; the de-dusting component 30 includes a mounting frame 301 which is rotatably and slidably arranged inside the tank body 10, a de-dusting frame 302 is arranged inside the mounting frame 301, and a de-dusting net 304 is arranged inside the de-dusting frame 302; a transmission component arranged between the stirring component 20 and the de-dusting component 30, which is used to drive the de-dusting component 30 to rotate and jump when adding and removing de-dusting.
[0027] The utility model adds protease raw materials into the tank body 10 through the feeding port 101, and the impurity removing component 30 removes impurities from the protease raw materials. At the same time, the stirring component 20 rotates and drives the impurity removing component 30 to rotate and jump, thereby improving the impurity removing efficiency. The utility model solves the problem of the need to remove impurities from the raw materials by setting the impurity removing component 30, and at the same time, the impurity removing component 30 can rotate and jump, thereby improving the impurity removing efficiency.
[0028] like Figure 1As shown, as a preferred embodiment of the utility model, the stirring component 20 includes a stirring shaft 201 rotatably mounted on the tank body 10 and a plurality of stirring blades 203 arranged in an array on the stirring shaft 201, and the stirring blades 203 are welded and arranged on the stirring shaft 201. In order to drive the stirring shaft 201 to rotate, a driving motor 202 is also provided on the tank body 10, and the driving motor 202 is transmission-connected with the stirring shaft 201. The driving motor 202 can be connected to the stirring shaft 201 through a gear or a coupling. In this way, the stirring shaft 201 drives the stirring blades 203 to rotate to provide power.
[0029] In order to realize the rotation of the mounting frame 301 and the elastic arrangement of the mounting frame 301 up and down inside the tank body 10, at least two elastic telescopic rods 306 are arranged at the bottom of the mounting frame 301, and the elastic telescopic rods 306 are fixedly mounted on the mounting ring 307, and the mounting ring 307 is rotatably arranged on the support seat 308, and the support seat 308 is fixedly mounted inside the tank body 10. The elastic telescopic rods 306 are fixedly mounted on the bottom of the mounting frame 301. The support seat 308 can be fixedly mounted inside the tank body 10 by bolts.
[0030] The transmission component includes a transmission telescopic rod 204 symmetrically arranged on the stirring shaft 201 and a matching block 305 fixedly installed at the bottom of the installation frame 301. A plurality of driving grooves 3051 are arranged in a circumferential array on the matching block 305. The transmission telescopic rod 204 is used to be inserted into the driving groove 3051 when the installation frame 301 is lowered. Specifically, when the protease raw material is added to the feeding port 101, the installation frame 301 compresses the elastic telescopic rod 306, the installation frame 301 drives the matching block 305 to descend, the transmission telescopic rod 204 hits the matching block 305, and at the same time, the driving motor 202 drives the stirring shaft 201 to rotate, the stirring shaft 201 drives the transmission telescopic rod 204 to rotate, the transmission telescopic rod 204 cooperates with the driving groove 3051, and drives the installation frame 301 to rotate.
[0031] like Figure 2As shown, as a preferred embodiment of the utility model, in order to make the installation frame 301 jump up and down during the rotation process, no less than two interference rods 3012 are arranged in an array on the outer side of the installation frame 301, and a support ring 3013 is sleeved on the outer side of the installation frame 301, and the support ring 3013 is fixedly installed inside the tank body 10; a plurality of interference protrusions 3014 are arranged in an array on the support ring 3013, and the interference protrusions 3014 are arranged on the track of the interference rod 3012. The interference rods 3012 are arranged in two, and the interference protrusions 3014 are arranged in an even number. Specifically, when the installation frame 301 rotates, the interference rods 3012 are driven to rotate, and the interference rods 3012 are in contact with the interference protrusions 3014 during the rotation process, so that the installation frame 301 slides up and down. If there are many attachments on the impurity removal net 304, which affects the impurity removal efficiency, the installation frame 301 is driven by gravity to drop, and the overlapping height of the contact rod 3012 and the contact protrusion 3014 vibrates, increasing the height of the installation frame 301 jumping, thus increasing the impurity removal efficiency; in this way, the efficiency can be automatically adjusted according to the impurity removal process. The impurity removal net 304 is an ultrafiltration impurity removal membrane with a molecular weight of 30,000.
[0032] In order to facilitate the replacement of the impurity removal net 304, the impurity removal frame 302 is slidably arranged inside the installation frame 301.
[0033] A plurality of guide slide blocks 3021 are arranged outside the impurity removal frame 302 , and the guide slide blocks 3021 are slidably arranged in the slide grooves 3011 inside the installation frame 301 , so that the impurity removal frame 302 can be slid up and down in the installation frame 301 .
[0034] like Figure 2 As shown, as a preferred embodiment of the utility model, the impurity removal net 304 is a barrel-shaped structure with an opening at the top. A pressure ring 303 is installed at the top opening of the impurity removal frame 302 to fix the bottom of the impurity removal net 304, so that the impurity removal net 304 is fixed. When the impurity removal net 304 needs to be cleaned, the pressure ring 303 can be removed from the impurity removal frame 302. The pressure ring 303 can be fixed on the impurity removal frame 302 by screw thread or by buckle.
[0035] In order to facilitate the removal of the mounting frame 301 from the tank body 10, the tank body 10 includes a lower tank body 11 and an upper tank body 12, wherein the lower tank body 11 is detachably arranged on the upper tank body 12. The lower tank body 11 can be connected to the upper tank body 12 by bolts. The stirring shaft 201 and the discharge port 102 are arranged on the lower tank body 11, and the discharge port 102 is arranged on the upper tank body 12.
[0036] The working principle of the utility model is:
[0037] The protease raw material is added into the tank body 10 through the feeding port 101, and the driving motor 202 is driven to rotate, so as to drive the stirring shaft 201 and the stirring blade 203 to rotate. The stirring shaft 201 drives the transmission telescopic rod 204 to drive the matching block 305 and the installation frame 301 to rotate, and the installation frame 301 drives the resistance rod 3012 to rotate. The resistance rod 3012 resists 3104 during the rotation, so that the installation frame 301 slides up and down, so that the impurity removal net 304 jumps up and down and rotates when removing impurities from the protease raw material, and the rotation utilizes the centrifugal force to improve the impurity removal efficiency, and the up and down jumping avoids clogging; if there are many attachments on the impurity removal net 304, which affects the impurity removal efficiency, the installation frame 301 descends under the drive of gravity at this time, and the overlapping height of the resistance rod 3012 and the resistance protrusion 3014 vibrates, so as to increase the jumping height of the installation frame 301, thereby increasing the impurity removal efficiency; in this way, the efficiency can be automatically adjusted according to the impurity removal process.
[0038] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.
[0039] In the present invention, unless otherwise clearly specified and limited, the terms "install", "connect", "connect", "fix" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0040] In the present utility model, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.
[0041] Although the embodiments of the present invention have been shown and described above, it can be understood that the above embodiments are exemplary and cannot be understood as limitations of the present invention. Ordinary technicians in the field can change, modify, replace and modify the above embodiments within the scope of the present invention.
Claims
1. A liquid preparation tank for preparing liquid medicine, characterized in that: include: A tank body (10), wherein the tank body (10) is provided with a feeding port (101) and a discharging port (102); A stirring component (20) is rotatably disposed inside the tank body (10); An impurity removal component (30) is arranged below the feeding port (101); the impurity removal component (30) comprises an installation frame (301) which is rotatably and slidably arranged inside the tank body (10); an impurity removal frame (302) is arranged inside the installation frame (301); and an impurity removal net (304) is arranged inside the impurity removal frame (302); And, a transmission component is arranged between the stirring component (20) and the impurity removing component (30), and is used to drive the impurity removing component (30) to rotate and jump when adding materials and removing impurities.
2. A liquid preparation tank for preparing liquid medicine according to claim 1, characterized in that: The stirring component (20) comprises a stirring shaft (201) rotatably mounted on the tank body (10) and a plurality of stirring blades (203) arranged in an array on the stirring shaft (201); the stirring blades (203) are welded and mounted on the stirring shaft (201).
3. A liquid preparation tank for preparing liquid medicine according to claim 2, characterized in that: At least two elastic telescopic rods (306) are arranged at the bottom of the installation frame (301), and the elastic telescopic rods (306) are fixedly mounted on the installation ring (307). The installation ring (307) is rotatably mounted on a support seat (308), and the support seat (308) is fixedly mounted inside the tank body (10).
4. A liquid preparation tank for preparing liquid medicine according to claim 3, characterized in that: The transmission component comprises a transmission telescopic rod (204) symmetrically arranged on the stirring shaft (201) and a matching block (305) fixedly installed at the bottom of the installation frame (301), wherein a plurality of driving grooves (3051) are arranged in a circumferential array on the matching block (305), and the transmission telescopic rod (204) is used to be inserted into the driving groove (3051) when the installation frame (301) descends.
5. A liquid preparation tank for preparing liquid medicine according to claim 4, characterized in that: At least two abutment rods (3012) are arranged in an array on the outside of the installation frame (301); a support ring (3013) is sleeved on the outside of the installation frame (301); the support ring (3013) is fixedly installed inside the tank body (10); a plurality of abutment protrusions (3014) are arranged in an array on the support ring (3013); the abutment protrusions (3014) are arranged on the track of the abutment rods (3012).
6. A liquid preparation tank for preparing liquid medicine according to claim 5, characterized in that: The impurity removal frame (302) is slidably arranged inside the installation frame (301) up and down.
7. A liquid preparation tank for preparing liquid medicine according to claim 6, characterized in that: A plurality of guide slide blocks (3021) are arranged outside the impurity removal frame (302), and the guide slide blocks (3021) are slidably arranged in the slide grooves (3011) inside the installation frame (301).
8. A liquid preparation tank for preparing liquid medicine according to claim 1, characterized in that: The impurity removal net (304) is a barrel-shaped structure with an opening at the top.
9. A liquid preparation tank for preparing liquid medicine according to claim 7, characterized in that: A pressure ring (303) for fixing the bottom of the impurity removal net (304) is installed at the top opening of the impurity removal frame (302).