Blood culture bottle

Abstract

The utility model relates to the technical field of microbial culture, and discloses a blood culture bottle which comprises a transparent bottle body, a bottle cap and an adsorption filter element, an inner cavity for accommodating a culture solution is formed in the transparent bottle body and is communicated with a bottle opening of the transparent bottle body; the bottle cap hermetically covers the bottle opening; the adsorption filter element comprises a filter element body, the filter element body is provided with fine pores, and the adsorption filter element is arranged in the inner cavity of the transparent bottle body and is used for absorbing substances for inhibiting microbial culture. According to the technical scheme of the utility model, the detection accuracy can be improved.

Description

Technical Field

[0001] The utility model relates to the technical field of microbial culture, in particular to a blood culture bottle. Background Art

[0002] Bacterial culture and testing of blood samples are necessary measures for diagnosing blood-borne infections. Sepsis and bacteremia caused by microbial invasion of the blood are clinically critical conditions. For patients with blood-borne infections, whether they can be effectively cured depends largely on rapid, timely and accurate bacterial culture test reports.

[0003] Currently, automated blood culture systems dominate the market, and are used with blood culture bottles for incubation and testing, mainly colorimetric and laser detection methods. Both of these detection methods require light to pass through the culture fluid in the blood culture bottle. However, in current blood culture bottles, a large amount of adsorbents for absorbing substances that inhibit microbial culture are placed in the blood culture bottles because they need to absorb antibiotics or other substances that inhibit microbial culture in the blood. A large amount of adsorbents dispersed in the blood culture bottles will block light and affect the test results. Utility Model Content

[0004] The main purpose of the utility model is to provide a blood culture bottle, aiming to improve the accuracy of detection.

[0005] In order to achieve the above-mentioned purpose, the blood culture bottle proposed by the utility model comprises:

[0006] A transparent bottle body, wherein the transparent bottle body is provided with an inner cavity for accommodating a culture solution, and the inner cavity is connected to a bottle mouth of the transparent bottle body;

[0007] a bottle cap, wherein the bottle cap sealing cover is disposed on the bottle mouth; and

[0008] The adsorption filter element comprises a filter element body, the filter element body has fine pores, and the adsorption filter element is arranged in the inner cavity of the transparent bottle body.

[0009] Optionally, the filter element body is a filter element with fine pores formed by sintering a high molecular polymer.

[0010] Optionally, the adsorption filter element further includes adsorption particles, and the adsorption particles are arranged inside the filter element body.

[0011] Optionally, the adsorption particles are activated carbon.

[0012] Optionally, the adsorption filter element is provided in plurality.

[0013] Optionally, the blood culture bottle further comprises a biochemical sensor, which is disposed at the bottom of the transparent bottle body and is used for biochemical colorimetric detection.

[0014] Optionally, the biochemical sensor is color-changing silica gel.

[0015] Optionally, the blood culture bottle further comprises a sealing plug, wherein the sealing plug is disposed in the bottle cap and has an interference fit with the inner circumferential wall of the bottle mouth of the transparent bottle body.

[0016] Optionally, the transparent bottle is made of polycarbonate.

[0017] Optionally, the capacity of the transparent bottle is 20ml to 40ml.

[0018] In the technical solution of the utility model, the inner cavity of the transparent bottle body contains culture fluid, and the adsorption filter element includes a filter element body. The filter element body has tiny pores for the culture fluid to flow through. When the culture fluid flows through the filter element body, the filter element body can adsorb antibiotics or other substances that inhibit microbial culture in the blood in the culture fluid, so that the bacteria in the culture fluid are not inhibited and grow normally. The adsorption filter element can be observed with the naked eye. When conducting inspections, the inspectors can easily control the light to avoid the adsorption filter element, thereby improving the accuracy of the inspection. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on the structures shown in these drawings without paying creative work.

[0020] Figure 1 This is a schematic diagram of the three-dimensional structure of an embodiment of a blood culture bottle provided by the utility model;

[0021] Figure 2 It is a schematic diagram of the three-dimensional structure of the bottle cap.

[0022] Description of Figure Numbers:

[0023]

[0024]

[0025] The realization of the purpose, functional features and advantages of the utility model will be further explained in conjunction with embodiments and with reference to the accompanying drawings. DETAILED DESCRIPTION

[0026] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0027] It should be noted that all directional indications in the embodiments of the present invention (such as up, down, left, right, front, back...) are only used to explain the relative position relationship, movement status, etc. between the components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication will also change accordingly.

[0028] In addition, the descriptions of "first", "second", etc. in the present utility model are only used for descriptive purposes and cannot be understood as indicating or implying their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In addition, the technical solutions between the various embodiments can be combined with each other, but they must be based on the ability of ordinary technicians in this field to implement them. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by the present utility model.

[0029] Please refer to Figure 1 to Figure 2 The utility model proposes a blood culture bottle 1000, comprising a transparent bottle body 1, a bottle cap 2 and an adsorption filter element 3; the transparent bottle body 1 is provided with an inner cavity for accommodating culture fluid, and the inner cavity is connected to the bottle mouth of the transparent bottle body 1; the bottle cap 2 is a sealing cover arranged at the bottle mouth; the adsorption filter element 3 comprises a filter element body, the filter element body has fine pores, and the adsorption filter element 3 is arranged in the inner cavity of the transparent bottle body 1.

[0030] In this embodiment, the inner cavity of the transparent bottle body 1 contains culture fluid 6, and the adsorption filter element 3 includes a filter element body. The filter element body has tiny pores for the culture fluid 6 to flow through. When the culture fluid 6 flows through the filter element body, the filter element body can adsorb antibiotics or other substances that inhibit microbial culture in the blood in the culture fluid 6, so that the bacteria in the culture fluid 6 are not inhibited and grow normally. The adsorption filter element 3 can be observed with the naked eye. When performing detection, the detection personnel can easily control the light to avoid the adsorption filter element 3, thereby improving the accuracy of the detection.

[0031] In order to ensure good adsorption performance, the filter element body is a filter element with fine pores formed by sintering a high molecular polymer. There are many choices for the high molecular polymer, as long as it can capture the substances that inhibit the culture of microorganisms in the culture solution 6. In one embodiment of the utility model, the high molecular polymer is polypropylene, which has good chemical stability and low water absorption, can be used normally in the culture solution 6, and will not absorb the water in the culture solution 6. Polypropylene has the characteristics of low density, so it can float on the culture solution 6 and will not block light. In another embodiment of the utility model, the high molecular polymer is polyethylene, which also has the advantages of good chemical stability, low density, etc., and meets the use requirements.

[0032] Specifically, in one embodiment of the utility model, the adsorption filter element 3 also includes adsorption particles, which are arranged inside the filter element body. The filter element body is sintered from a high molecular polymer, has a large surface area and fine pores, and can effectively capture substances that inhibit microbial culture in the culture solution 6. The adsorption particles have adsorption properties and can adsorb substances that inhibit microbial culture in the culture solution 6. When the adsorption filter element 3 is placed in the transparent bottle body 1, it will directly contact the culture solution 6 to adsorb antibiotics or other substances that inhibit microbial culture in the blood, so that the bacteria in the culture solution 6 are not inhibited and grow normally. In addition, due to its own light weight, the filter element body can float on the culture solution 6 when placed in the transparent bottle body 1, and adsorb substances that inhibit microbial culture in the culture solution 6 through contact with the culture solution 6, and will not block light, so that the staff can detect the blood in the transparent bottle body 1 by colorimetry or laser detection.

[0033] There are many choices for adsorption particles. In one embodiment of the utility model, the adsorption particles are activated carbon, which is an adsorption material with a highly porous structure that can adsorb organic matter, gas and some soluble substances. In another embodiment of the utility model, the adsorption particles are polystyrene adsorption resins, which can adsorb drug residues such as antibiotics and antibacterial agents in the blood to reduce the interference of antibiotics on culture results.

[0034] Further, in order to ensure the adsorption effect, in one embodiment of the present utility model, please refer to Figure 1 There are multiple adsorption filter elements 3, and the multiple adsorption filter elements 3 float on the culture solution 6. Through contact with the culture solution 6, they adsorb antibiotics or other substances that inhibit microbial culture in the blood, so that the bacteria in the culture solution 6 are not inhibited and grow normally.

[0035] To adapt to the biochemical colorimetric detection system, please refer to Figure 1The blood culture bottle 1000 also includes a biochemical sensor 4, which is arranged at the bottom of the transparent bottle body 1. The biochemical sensor 4 is used for biochemical colorimetric detection. In one embodiment of the utility model, the biochemical sensor 4 is a color-changing silica gel, which has the property of changing color. The color-changing silica gel is usually mixed with silica gel and an indicator. The indicator is a chemical substance that will produce a color-changing or color-changing reaction under different humidity conditions. This indicator can be a chemical reagent or a dye or pigment. The silica gel allows acidic gases such as CO2 to pass through but is impermeable to water molecules. The growth of microorganisms in the culture solution 6 produces acidic gases, which causes the silica gel to change color, so that it can be adapted to the biochemical colorimetric detection system.

[0036] Further, in one embodiment of the present invention, please refer to Figure 2 The blood culture bottle 1000 also includes a sealing plug 5, which is arranged in the bottle cap 2. The sealing plug 5 is interference fit with the inner circumferential wall of the bottle mouth of the transparent bottle body 1. After the bottle cap 2 is connected to the transparent bottle body 1, the sealing plug 5 can be squeezed into the transparent bottle body 1 through the bottle mouth of the transparent bottle body 1. Since the sealing plug 5 and the inner circumferential wall of the bottle mouth of the transparent bottle body 1 are interference fit, there is no gap between the sealing plug 5 and the inner circumferential wall of the bottle mouth, thereby avoiding air exchange between the transparent bottle body 1 and the outside world, ensuring good sealing performance, and preventing the blood sample in the transparent bottle body 1 from leaking or being contaminated by the outside world.

[0037] Specifically, in one embodiment of the present invention, the transparent bottle body 1 is made of polycarbonate, which has good optical properties, a transparency close to that of glass, and can transmit most visible light, making it convenient for workers to detect the blood in the transparent bottle body 1 by colorimetry or laser detection, and has high strength and rigidity, and can maintain a stable shape when subjected to a large external force, thereby protecting the items in the transparent bottle body 1. In another embodiment of the present invention, the transparent bottle body 1 is made of polyethylene terephthalate, which has good heat insulation and transparency, and can effectively protect the items in the transparent bottle body 1.

[0038] Furthermore, in one embodiment of the utility model, considering that the current clinical laboratory department usually collects 8 to 10 ml of blood from adults and 1 to 3 ml of blood from children for culture testing in specific practice, the amount of blood collected by adults is significantly different from that of children. At present, the automated blood culture system occupies a dominant position on the market, and its matching blood culture bottle 1000 is an adaptation instrument that adopts a blood culture bottle system of uniform specifications. After actual measurement, the commercial blood culture bottle system on the market is about 80 ml with little difference. The adult blood culture bottle 1000 is the same size as the children's blood culture bottle 1000, the difference is that the amount of liquid in the bottle is different, and the liquid volume of each manufacturer is also different, ranging from 20ml to 40ml. In the treatment of clinical bloodstream infection, continuous blood sampling and culture monitoring of the treatment effect is required. The problem of large blood collection volume brings great psychological pressure and poor compliance to patients, which is particularly prominent in children. Since the blood culture standard recommends a blood collection volume of 1 to 3 ml for children, the currently popular 80 ml system culture bottle is relatively large, and it is relatively difficult to draw blood from infants and young children in clinical use. The huge blood culture bottle 1000 brings great psychological pressure to children and parents, and the patient compliance is poor, and we have received a lot of relevant feedback. To address this problem, we designed a small system blood culture bottle 1000, with a transparent bottle body 1 with a capacity of 20 to 40 ml, which eliminates the psychological pressure of patients when drawing blood and improves patient compliance and experience.

[0039] The above description is only a preferred embodiment of the present invention, and does not limit the patent scope of the present invention. All equivalent structural changes made by using the contents of the present invention specification and drawings under the inventive concept of the present invention, or directly / indirectly applied in other related technical fields are included in the patent protection scope of the present invention.

Claims

1. A blood culture bottle, characterized in that: include: A transparent bottle body, wherein the transparent bottle body is provided with an inner cavity for accommodating a culture solution, and the inner cavity is connected to a bottle mouth of the transparent bottle body; A bottle cap, wherein the bottle cap sealing cover is arranged on the bottle mouth; as well as The adsorption filter element comprises a filter element body, the filter element body has fine pores, and the adsorption filter element is arranged in the inner cavity of the transparent bottle body.

2. The blood culture bottle according to claim 1, characterized in that The filter element body is a filter element with fine pores formed by sintering a high molecular polymer.

3. The blood culture bottle according to claim 1, characterized in that: The adsorption filter element further comprises adsorption particles, and the adsorption particles are arranged inside the filter element body.

4. The blood culture bottle according to claim 3, characterized in that: The adsorption particles are activated carbon.

5. The blood culture bottle according to claim 1, characterized in that: The adsorption filter element is provided in plurality.

6. The blood culture bottle according to any one of claims 1 to 5, characterized in that: The blood culture bottle also includes a biochemical sensor, which is arranged at the bottom of the transparent bottle body and is used for biochemical colorimetric detection.

7. The blood culture bottle according to claim 6, characterized in that: The biochemical sensor is color-changing silica gel.

8. The blood culture bottle according to any one of claims 1 to 5, characterized in that: The blood culture bottle also includes a sealing plug, which is arranged in the bottle cap and has an interference fit with the inner circumferential wall of the bottle mouth of the transparent bottle body.

9. The blood culture bottle according to any one of claims 1 to 5, characterized in that: The transparent bottle is made of polycarbonate.

10. The blood culture bottle according to any one of claims 1 to 5, characterized in that: The capacity of the transparent bottle is 20ml to 40ml.

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