Raw material extraction device for producing atorvastatin calcium

By designing an extraction device including a quantitative feed silo, agitator leaf, centrifugal cylinder and extrusion box, the problems of raw material adhesion, waste of extract and low efficiency in traditional extraction devices are solved, and quantitative feed and efficient extraction are achieved Liquid separation improves the extraction effect and efficiency.

CN222468121UActive Publication Date: 2025-02-14NANJING HUAWE MEDICINE TECH DEV
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Patent Information

Application Number
CN202421262836.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-04
Publication Date
2025-02-14
Estimated Expiration
2034-06-04

AI Technical Summary

Technical Problem

During the extraction process of raw materials for atorvastatin calcium production, traditional extraction devices have problems such as raw material adhesion, waste of extract, poor extraction effect and low efficiency, and the amount of extract cannot be effectively controlled.

Method used

An extraction device including a quantitative feed silo, a weighing plate, a gravity sensor, agitating blade, a centrifugal cylinder and an extrusion chamber was designed to improve the extraction effect and efficiency by quantitative feeding, full stirring, centrifugal separation and extrusion separation. .

Benefits of technology

The quantitative feed and quantity control of the raw materials for atorvastatin calcium production is achieved, reducing the waste of extract and improving the extraction effect and efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a raw material extraction device for producing atorvastatin calcium, which comprises an extraction box, the extraction box is provided with a discharge pipe, a quantitative feed bin and a liquid inlet pipe used for leading in extract liquor, the inner bottom of the quantitative feed bin is provided with a support column, the support column is provided with a weighing plate, and a gravity sensor is arranged between the support column and the weighing plate. An annular flow guide table and a fixing rod are arranged in the extraction box, a centrifugal barrel is arranged below the annular flow guide table, a mixing cavity is formed above the annular flow guide table, a fixing pipe is arranged on the annular flow guide table, a rotating shaft is arranged in the mixing cavity, a deslagging pipe is arranged at the bottom of the centrifugal barrel, an extrusion box is arranged on the fixing rod, and the deslagging pipe is communicated with the extrusion box; through the arrangement of the weighing plate and the gravity sensor, the quantity of raw materials for producing atorvastatin calcium can be conveniently observed and controlled, and quantitative feeding is realized, so that the quantity of corresponding extract liquor is estimated, the waste of the extract liquor is reduced, and resources are saved.
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Description

Technical Field

[0001] The utility model relates to the technical field of extraction, in particular to a raw material extraction device for producing atorvastatin calcium. Background Art

[0002] Drugs refer to substances used to prevent, treat, and diagnose human diseases, purposefully regulate human physiological functions, and have prescribed indications or functional indications, usage, and dosage, including traditional Chinese medicine, chemical drugs, and biological products. The processing of atorvastatin calcium involves the extraction of raw materials for the production of atorvastatin calcium.

[0003] However, when the conventional extraction device performs mixed extraction on the raw materials and the extract for the production of atorvastatin calcium, the raw materials may adhere to the inner wall of the extraction box during the stirring process. The extract is collected after the extraction, but there is still residual extract in the raw material residue after the extraction, resulting in waste of the extract, poor extraction effect, and low extraction efficiency. At the same time, when the raw materials for the production of atorvastatin calcium are extracted, the amount of the extract cannot be controlled. When the amount of the extract is small, the raw materials cannot be well extracted. When the amount of the extract is large, the extract will be wasted. Utility Model Content

[0004] The utility model aims to solve the technical problems existing in the prior art and provide a raw material extraction device for producing atorvastatin calcium.

[0005] To achieve the above-mentioned purpose, the technical solution provided by the utility model is: a raw material extraction device for the production of atorvastatin calcium, comprising an extraction box, the extraction box is provided with a discharge pipe, a quantitative feed bin and a liquid inlet pipe for introducing an extract, a support column is provided at the bottom of the quantitative feed bin, a weighing plate is provided on the support column, and a gravity sensor is provided between the support column and the weighing plate, an annular guide table and a fixed rod are provided in the extraction box, a centrifugal cylinder is provided below the annular guide table, a mixing chamber is provided above the annular guide table, a fixed pipe connected to the mixing chamber is provided on the annular guide table, a rotating shaft is provided in the mixing chamber, the rotating shaft passes through the fixed pipe and is fixedly connected to the bottom of the centrifugal cylinder, a slag discharge pipe is provided at the bottom of the centrifugal cylinder, an extrusion box is provided on the fixed rod, and the slag discharge pipe is connected to the extrusion box.

[0006] Preferably, the extraction box is provided with a motor, the motor is connected to the rotating shaft, the mixing chamber includes a connecting rod and a stirring blade, the connecting rod and the stirring blade are both arranged on the rotating shaft, the connecting rod is provided with a cleaning brush, and the cleaning brush abuts against the inner wall of the mixing chamber.

[0007] Preferably, filter holes are arranged on the cylinder wall of the centrifugal cylinder, a fixing seat is fixedly arranged on the bottom of the centrifugal cylinder, and the fixing seat is fixedly connected to the rotating shaft.

[0008] Preferably, a ball bearing is arranged between the neck of the centrifugal cylinder and the fixed tube to form a rotating structure.

[0009] Preferably, an electric push rod is arranged in the extrusion box, an extrusion plate is arranged on the electric push rod, a liquid outlet is arranged on the extrusion box, and a filter is arranged in the liquid outlet.

[0010] Preferably, the extraction box is provided with a box door for sealing, the weighing plate is provided with a feed pipe, and the feed pipe, liquid inlet pipe, slag discharge pipe and discharge pipe are all provided with electric valves.

[0011] Beneficial effects of the utility model:

[0012] The utility model can conveniently observe and control the amount of raw materials used in the production of atorvastatin calcium through the arrangement of a weighing plate and a gravity sensor, realize quantitative feeding, and thus estimate the amount of the corresponding extract, thereby reducing the waste of the extract and saving resources.

[0013] The utility model fully stirs and mixes the raw materials and the extract for producing atorvastatin calcium by means of a stirring blade, and then separates the extract by centrifugal separation of the extract by a centrifugal cylinder and separates the extract in the residue in the centrifugal cylinder by squeezing in an extrusion box, thereby improving the extraction effect and efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] The drawings described herein are used to provide a further understanding of the present invention and constitute a part of the present invention. The illustrative embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an improper limitation on the present invention.

[0015] Figure 1 This is a schematic diagram of the internal structure of the extraction box of the utility model;

[0016] Figure 2 This is a schematic diagram of the structure of the quantitative feeding bin of the utility model;

[0017] Figure 3 It is a schematic diagram of the external structure of the extraction box of the utility model.

[0018] Figure annotation:

[0019] 1-extraction box 2-motor 3-quantitative feeding bin 4-rotating shaft 5-stirring blade 6-annular guide table 7-fixed tube 8-ball 9-filter hole 10-centrifugal cylinder 11-fixed seat 12-slag discharge pipe 13-extrusion box 14-fixed rod 15-extrusion plate 16-electric push rod 17-filter screen 18-discharge pipe 19-liquid inlet pipe 20-weighing plate 21-gravity sensor 22-support column 23-feeding pipe 24-connecting rod 25-cleaning brush. DETAILED DESCRIPTION

[0020] This section will describe in detail the specific embodiments of the utility model. The preferred embodiments of the utility model are shown in the accompanying drawings. The purpose of the accompanying drawings is to supplement the description of the text part of the specification with graphics, so that people can intuitively and vividly understand each technical feature and the overall technical solution of the utility model, but it cannot be understood as a limitation on the protection scope of the utility model.

[0021] In the description of the present invention, it should be understood that descriptions involving orientation, such as up, down, front, back, left, right, etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0022] In the description of the present utility model, "several" means one or more, "more" means more than two, "greater than", "less than", "exceed" etc. are understood to exclude the number itself, and "above", "below", "within" etc. are understood to include the number itself. If there is a description of "first" or "second", it is only used for the purpose of distinguishing the technical features, and cannot be understood as indicating or implying the relative importance or implicitly indicating the number of the indicated technical features or implicitly indicating the order of the indicated technical features.

[0023] In the description of the present invention, unless otherwise clearly defined, terms such as setting, installing, connecting, etc. should be understood in a broad sense, and technicians in the relevant technical field can reasonably determine the specific meanings of the above terms in the present invention based on the specific content of the technical solution.

[0024] Example 1

[0025] Reference Figure 1-Figure 3The preferred embodiment of the utility model is a raw material extraction device for the production of atorvastatin calcium, comprising an extraction box 1, the extraction box 1 is provided with a discharge pipe 18, a quantitative feed bin 3 and a liquid inlet pipe 19 for introducing an extract, the bottom of the quantitative feed bin 3 is provided with a support column 22, a weighing plate 20 is provided on the support column 22, a feed pipe 23 is provided on the weighing plate 20, an electric valve is provided on the feed pipe 23, and a gravity sensor 21 is provided between the support column 22 and the weighing plate 20, (the gravity sensor 21 is connected to the outside with a display The control box of the screen is electrically connected (this technical means is a conventional technical means and will not be described in detail)) The extraction box 1 is provided with an annular guide table 6 and a fixed rod 14, a centrifugal cylinder 10 is provided below the annular guide table 6, and a mixing chamber is provided above the annular guide table 6. A motor 2 is provided on the extraction box 1, and the motor 2 is connected to the rotating shaft 4. The mixing chamber includes a connecting rod 24 and a stirring blade 5, and the connecting rod 24 and the stirring blade 5 are both arranged on the rotating shaft 4. A cleaning brush 25 is provided on the connecting rod 24, and the cleaning brush 25 abuts against the inner wall of the mixing chamber.

[0026] Specifically, the utility model weighs the raw materials for the production of atorvastatin calcium entering the extraction box 1 through the weighing plate 20 in the quantitative feeding bin 3, and transmits the gravity data on the weighing plate to the outside world through the gravity sensor 21. The utility model can conveniently observe and control the amount of raw materials for the production of atorvastatin calcium through the arrangement of the weighing plate 20 and the gravity sensor 21, realize quantitative feeding, and thus estimate the amount of the corresponding extract, reduce the waste of the extract, and save resources; after the raw materials for the production of atorvastatin calcium and the extract enter the mixing chamber in the extraction box 1, the motor 2 drives the rotating shaft 4 to rotate, the rotating shaft 4 drives the stirring blade 5 and the connecting rod 24 to rotate, the stirring blade 5 fully stirs and mixes the raw materials for the production of atorvastatin calcium and the extract to improve the extraction effect, and the connecting rod 24 drives the cleaning brush 25 to clean the inner wall of the extraction box 1 to prevent the raw materials for the production of atorvastatin calcium from adhering to the inner wall of the extraction box 1, thereby improving the extraction effect.

[0027] Example 2

[0028] The annular guide platform 6 is provided with a fixed pipe 7 connected with the mixing chamber, the rotating shaft 4 passes through the fixed pipe 7 and is fixedly connected with the bottom of the centrifugal cylinder 10, the bottom of the centrifugal cylinder 10 is provided with a slag discharge pipe 12, the fixed rod 14 is provided with an extrusion box 13, and the slag discharge pipe 12 is connected with the extrusion box 13.

[0029] In this embodiment, filter holes 9 are provided on the wall of the centrifugal cylinder 10, and a fixing seat 11 is fixedly provided at the bottom of the centrifugal cylinder 10, and the fixing seat 11 is fixedly connected to the rotating shaft 4; a ball 8 is provided between the neck of the centrifugal cylinder 10 and the fixed tube 7 to form a rotating structure, so that the centrifugal cylinder 10 can rotate with the stirring shaft 4.

[0030] Specifically, the raw materials and extract for the production of atorvastatin calcium fall into the centrifuge cylinder 10 along the fixed tube 7 after being stirred, and the rotating shaft 4 drives the centrifuge cylinder 10 to rotate, so that centrifugal force is generated in the centrifuge cylinder 10, and the extract is thrown out through the filter hole 9 and falls into the extraction box 1, and the filter residue remains in the centrifuge cylinder 10, completing the initial separation, and finally enters the extrusion box 13 through the residue discharge pipe 12.

[0031] In this embodiment, an electric push rod 16 is disposed in the squeezing box 13 , a squeezing plate 15 is disposed on the electric push rod 16 , a liquid outlet is disposed on the squeezing box 13 , and a filter screen 17 is disposed in the liquid outlet.

[0032] Specifically, the electric push rod 16 drives the extrusion plate 15 to move in the horizontal direction, and the material after centrifugation by the centrifuge cylinder 10 is squeezed on the inner wall of the extrusion box 13 to squeeze out the residual liquid. The liquid passes through the filter screen 17 in the liquid outlet and falls into the extraction box 1, and is then discharged from the discharge pipe 18 to complete the secondary separation, thereby achieving the separation of the residual liquid in the residue and improving the extraction effect.

[0033] Furthermore, the extraction box 1 is provided with a box door for sealing, and the liquid inlet pipe 19 , the slag discharge pipe 12 , and the material discharge pipe 18 are all provided with electric valves.

[0034] In summary, the utility model can conveniently observe and control the amount of raw materials for atorvastatin calcium production through the arrangement of the weighing plate 20 and the gravity sensor 21, realize quantitative feeding, and thus estimate the amount of the corresponding extract, thereby reducing the waste of the extract and saving resources.

[0035] The utility model fully stirs and mixes the raw materials and the extract for producing atorvastatin calcium through the stirring blade 5, and then separates the extract by centrifugation through the centrifuge 10 and squeezes and separates the extract in the residue in the centrifuge 10 in the squeezing box 13, thereby improving the extraction effect and efficiency.

[0036] Under the premise that no conflict occurs, those skilled in the art may freely combine and superimpose the above-mentioned additional technical features.

[0037] The above description is only a preferred implementation mode of the present utility model. Any technical solution that achieves the purpose of the present utility model by substantially the same means shall fall within the protection scope of the present utility model.

Claims

1. A raw material extraction device for the production of atorvastatin calcium, characterized in that: The invention comprises an extraction box (1), wherein the extraction box (1) is provided with a discharge pipe (18), a quantitative feed bin (3) and a liquid inlet pipe (19) for introducing an extraction liquid, wherein a support column (22) is provided at the bottom of the quantitative feed bin (3), a weighing plate (20) is provided on the support column (22), and a gravity sensor (21) is provided between the support column (22) and the weighing plate (20), wherein an annular flow guide platform (6) and a fixing rod (14) are provided in the extraction box (1), wherein the annular flow guide platform (6) ) is provided below the annular guide platform (6), a mixing chamber is provided above the annular guide platform (6), a fixed pipe (7) connected to the mixing chamber is provided on the annular guide platform (6), a rotating shaft (4) is provided in the mixing chamber, the rotating shaft (4) passes through the fixed pipe (7) and is fixedly connected to the bottom of the centrifugal cylinder (10), a slag discharge pipe (12) is provided at the bottom of the centrifugal cylinder (10), an extrusion box (13) is provided on the fixed rod (14), and the slag discharge pipe (12) is connected to the extrusion box (13).

2. The raw material extraction device for producing atorvastatin calcium according to claim 1, characterized in that: The extraction box (1) is provided with a motor (2), the motor (2) is connected to the rotating shaft (4), the mixing chamber comprises a connecting rod (24) and a stirring blade (5), the connecting rod (24) and the stirring blade (5) are both arranged on the rotating shaft (4), the connecting rod (24) is provided with a cleaning brush (25), and the cleaning brush (25) abuts against the inner wall of the mixing chamber.

3. The raw material extraction device for producing atorvastatin calcium according to claim 1, characterized in that: The centrifugal cylinder (10) has filter holes (9) arranged on its wall, and a fixing seat (11) is fixedly arranged on the bottom of the centrifugal cylinder (10), wherein the fixing seat (11) is fixedly connected to the rotating shaft (4).

4. The raw material extraction device for producing atorvastatin calcium according to claim 1, characterized in that: A ball (8) is arranged between the neck of the centrifugal cylinder (10) and the fixed tube (7) to form a rotating structure.

5. The raw material extraction device for producing atorvastatin calcium according to claim 1, characterized in that: An electric push rod (16) is arranged in the extrusion box (13), an extrusion plate (15) is arranged on the electric push rod (16), a liquid outlet is arranged on the extrusion box (13), and a filter screen (17) is arranged in the liquid outlet.

6. The raw material extraction device for producing atorvastatin calcium according to claim 1, characterized in that: The extraction box (1) is provided with a box door for sealing, the weighing plate (20) is provided with a feed pipe (23), and the feed pipe (23), the liquid inlet pipe (19), the slag discharge pipe (12), and the discharge pipe (18) are all provided with electric valves.

Citation Information

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