Immunoreagent strip clamping shell

By designing the immune reagent strips to be stuck, using upper and lower clamping structures and double bevel structures, uniform diffusion of samples and multi-channel parallel detection are achieved, solving the problem that multiple indicators cannot be detected simultaneously in the existing technology, and improving the detection efficiency and accuracy.

CN222482255UActive Publication Date: 2025-02-14JIANGNAN UNIV
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Patent Information

Application Number
CN202420711094.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-08
Publication Date
2025-02-14
Estimated Expiration
2034-04-08

AI Technical Summary

Technical Problem

The existing immunochromatography test strips cannot detect multiple indicators at the same time, resulting in inefficient detection and problems of uneven diffusion and time difference.

Method used

An immune reagent strip jam was designed, adopting an upper and lower clamping structure, including multiple clamp slots and display windows, combined with a double bevel structure, to achieve uniform diffusion of the sample and multi-channel parallel detection.

Benefits of technology

The advantage of detecting multiple indicators simultaneously is realized, ensuring the accuracy and efficiency of the detection results, reducing experimental errors, and solving the time difference problem.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to an immunoreagent strip clamping shell, and belongs to the technical field of biological detection. The utility model provides an immunoreagent strip clamping shell which comprises an upper clamping shell and a lower clamping shell which are clamped with each other, and a multi-channel parallel structure is arranged to be matched with a double-inclined-surface part, so that the advantage of simultaneously detecting a plurality of indexes can be realized; and a good effect of slowly overflowing along the inclined surfaces and uniformly entering the clamping groove at the same time can be formed under the action of the double inclined surfaces, so that nine indexes can be detected at the same time. Meanwhile, the reagent strip clamping shell is arranged to be of an up-down clamping structure and is convenient to disassemble and splice at any time, and the clamping shell can be adjusted to be placed on the horizontal plane by utilizing a gradienter before detection so as to ensure the accuracy of a detection result.
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Description

Technical Field

[0001] The utility model relates to an immune reagent strip card shell, belonging to the technical field of biological detection. Background Art

[0002] Immunochromatography is a simple and rapid diagnostic method and an important tool for point of care testing (POCT). It was first used for the detection of human chorionic gonadotropin (HCG) as a basis for the diagnosis of early pregnancy. Immunochromatography is mainly performed with the help of immunochromatography test strips. Immunochromatography is not only easy to operate, fast in detection, highly specific, stable, but also easy to carry. It has been widely used in clinical diagnosis, food safety, drug testing, environmental pollution and other fields.

[0003] In recent years, immunochromatography technology has been increasingly used in the field of rapid testing. It combines the advantages of immunology and chromatography technology to provide a fast, simple, and highly sensitive detection method for target substances in various samples. However, most of the test strips currently on the market can only detect one or two indicators at the same time, and cannot detect multiple indicators of a sample at the same time. During rapid testing, testers need to bring different types of reagent strips for separate testing, which has the defect of low efficiency.

[0004] At present, although there is a parallel arrangement of multiple detection slots structure disclosed in publication number CN213023170U, it is difficult to achieve uniform diffusion in each detection slot after the sample is added. There will be uneven diffusion and even slow diffusion speed in some detection slots, which will affect the detection efficiency.

[0005] In addition, the existing test strip structure cannot solve the problem of time difference between the previous and next tests in some actual test application environments, such as (1) rapid food safety detection: In the field of food safety, in order to ensure the immediate safety of food, it is necessary to perform rapid tests on multiple indicators at the same time. For example, on a food production line, it may be necessary to simultaneously detect indicators such as microbial contamination, chemical residues, and physical pollutants in food. The detection of these indicators needs to be carried out simultaneously to ensure the timely release of food or take corresponding treatment measures. (2) Real-time readings for environmental monitoring: In some environmental monitoring scenarios, such as air pollution monitoring or water pollution monitoring, it is necessary to obtain concentration data of multiple pollutants in real time. These pollutants may include microorganisms, harmful substances, heavy metals, etc. In order to accurately assess the environmental conditions, these indicators need to be detected simultaneously without time difference so that timely countermeasures can be taken. With respect to the above-mentioned time difference problems, the test strip structures of the prior art (including CN213023170U) cannot solve them accordingly, which greatly reduces the efficiency in the actual production process. Utility Model Content

[0006] In order to solve the above problems, the utility model provides an immunoreagent strip card shell, comprising an upper card shell and a lower card shell that are mutually engaged, wherein the lower card shell has a plurality of card slots, a first inclined portion connected to the plurality of card slots, a second inclined portion connected to the first inclined portion, and a sample absorption structure connected to the second inclined portion;

[0007] The upper card housing comprises a plurality of display windows corresponding to the card slots and a sample loading window corresponding to the sample absorption structure; a test strip can be placed in the card slot;

[0008] At least a portion of the upper surface of the upper chuck or the lower chuck is provided with a level.

[0009] Furthermore, the upper card shell and the lower card shell are connected via a card connector.

[0010] In an implementation manner of the utility model, there are nine card slots connected side by side, and each card slot has the same size.

[0011] In an implementation manner of the present utility model, each display window corresponding to the card slot is an elliptical transparent window.

[0012] Furthermore, the sample absorption structure includes a partition portion close to one side of the second inclined portion and a sample loading groove, and a gap is left between the partition portion and the bottom of the lower casing.

[0013] In one embodiment of the present invention, the sample adding slot is provided with an absorption pad.

[0014] Further, the slope of the first inclined surface portion is greater than the slope of the second inclined surface portion.

[0015] In the present invention, the terms "first" and "second" are only used to distinguish similar components / parts with different positions or different characteristics and have no other limiting meanings; the term "upper" refers to the direction of each component away from the ground, and the term "lower" refers to the direction of each component close to the ground.

[0016] Beneficial effects of the utility model:

[0017] The utility model can achieve the advantage of detecting multiple indicators at the same time by setting a multi-channel parallel structure and cooperating with the double inclined surface, and can also form a good effect of slowly overflowing along the inclined surface and evenly entering the card slot at the same time under the action of the double inclined surface, thereby ensuring that nine indicators are detected at the same time, so that the reaction differences of different test strips can be observed through parallel control experiments, and it is helpful to reduce experimental errors, avoid changes in samples due to different placement times, and solve the time difference problem in the simultaneous detection process. At the same time, the reagent strip card shell is set as an upper and lower card connection structure, which is convenient for disassembly and splicing at any time, and before the test, the card shell can also be adjusted to a horizontal plane using a level meter to ensure the accuracy of the test results. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a schematic diagram of the structure after the upper card shell and the lower card shell are separated in one embodiment of the utility model.

[0019] Figure 2 It is a schematic structural diagram of an upper locking shell and a lower locking shell after locking in one embodiment of the utility model.

[0020] Figure 3 It is a structural side view of an embodiment of the utility model after the upper locking shell and the lower locking shell are locked.

[0021] In the figure, 1, upper casing; 11, sample loading window; 12, display window; 13, snap hole; 2, lower casing; 21, absorption pad; 221, first inclined portion, 222, second inclined portion; 23, slot; 24, snap column, 25, partition portion, 26, sample loading slot, 3: level. DETAILED DESCRIPTION

[0022] Example 1

[0023] The utility model provides an immunological reagent strip card shell, comprising an upper card shell 1 and a lower card shell 2, wherein the upper card shell 1 is connected to the lower card shell 2 through a buckle hole 13 and a buckle column 24, and the lower card shell 2 has nine card slots 23 connected in parallel and having the same size, a first inclined surface 221 connected to the nine card slots 23, a second inclined surface 222 connected to the first inclined surface 221, and a sample absorption structure connected to the second inclined surface 222, wherein each card slot 23 is equipped with a test paper strip; the sample absorption structure comprises a partition portion 25 close to one side of the second inclined surface 222 and a sample adding slot 26, wherein a gap is left between the partition portion 25 and the bottom of the lower card shell 2, and the sample adding slot 23 is provided with an absorption pad 21.

[0024] The upper card housing 1 includes nine oval transparent display windows 12 corresponding to the card slots 23 and a sample loading window 11 corresponding to the sample absorption structure; a test strip can be placed in the card slots 23;

[0025] At least a portion of the upper surface of the upper card shell 1 or the lower card shell 2 is provided with a level meter 3, which is convenient for checking whether the immunoreagent strip card shell is in a horizontal position before testing to ensure accuracy and facilitate uniform dispersion, and can further promote the nine card slots to absorb samples for testing at the same time.

[0026] Furthermore, the slope of the first inclined portion 221 is greater than the slope of the second inclined portion 222, so that after passing through the gap, the sample can slowly climb / overflow to the top along the second inclined portion 222 and be evenly and quickly dispersed to the test strips in each card slot, preventing problems such as uneven dispersion of the nine channels or poor sample flow.

[0027] The working principle of this utility model:

[0028] The sample is added from the sample adding window 11 so that the sample enters the sample adding slot 26. After passing through the gap below the partition 25, the sample in the sample adding slot 26 will first slowly climb to the top of the first inclined portion 221, and then quickly and evenly disperse along the second inclined portion 222 into the test strips fixed to the nine card slots 23. If the test item measured by the card slot is positive, two clear strips can be seen on the corresponding display window 12; if the test item measured is negative, a clear strip can be seen on the corresponding display window 12. In addition, different batches of tests can be performed by replacing the test strips on the card slot 23.

[0029] Although the present invention has been disclosed as above in terms of preferred embodiments, it is not intended to limit the present invention. Anyone familiar with the technology may make various changes and modifications without departing from the spirit and scope of the present invention. Therefore, the scope of protection of the present invention should be based on the definition of the claims.

Claims

1. An immunoassay reagent strip cartridge, characterized in that: It comprises an upper card shell and a lower card shell which are connected to each other, wherein the lower card shell has a plurality of card slots, a first inclined portion connected to the plurality of card slots, a second inclined portion connected to the first inclined portion, and a sample absorption structure connected to the second inclined portion; The upper card housing includes a plurality of display windows corresponding to the card slots and a sample loading window corresponding to the sample absorption structure; At least a portion of the upper surface of the upper chuck or the lower chuck is provided with a level.

2. The immunoassay reagent strip cartridge according to claim 1, characterized in that: The upper card shell is connected with the lower card shell through a card connector.

3. The immunoassay reagent strip cartridge according to claim 1, characterized in that: There are nine card slots which are connected side by side, and each card slot has the same size.

4. The immunoassay reagent strip cartridge according to claim 3, characterized in that: Each display window corresponding to the card slot is an elliptical transparent window.

5. The immunoassay reagent strip cartridge according to claim 1, characterized in that: The sample absorption structure comprises a partition portion close to one side of the second inclined portion and a sample adding groove, and a gap is left between the partition portion and the bottom of the lower casing.

6. The immunoassay reagent strip cartridge according to claim 5, characterized in that: The sample adding groove is provided with an absorption pad.

7. The immunoassay reagent strip cartridge according to claim 1, characterized in that: The slope of the first slope portion is greater than the slope of the second slope portion.

Citation Information

Patent Citations

  • Piece of shell clamping test paper for realizing one-time sample application detection of various medicines

    CN213023170U