Potassium sodium dehydroandroan drographolide succinate solid-liquid separation device

Abstract

The utility model discloses a potassium sodium dehydroandroan drographolide succinate solid-liquid separation device, relates to the field of medicine separation, and aims to solve the problems that continuous solid-liquid separation of a large amount of extracts cannot be realized and the separation efficiency is relatively high in the conventional potassium sodium dehydroandroan drographolide succinate solid-liquid separation. The device comprises a separation box, a filter cartridge, a collection cylinder, a liquid storage box, a medicine residue collection box and a filter screen, the filtering efficiency of the filtering net can be remarkably improved through the arranged filtering barrel and the collecting barrel, and the problem that a large number of solid phases and liquid phases are accumulated on the filtering net is solved. The device disclosed by the utility model can realize long-time solid-liquid separation of a large amount of potassium sodium dehydroandroan drographolide succinate extract, and is suitable for industrial mass production.

Description

Technical Field

[0001] The utility model belongs to the field of drug separation, and in particular relates to a solid-liquid separation device for linalool. Background Art

[0002] Yanhuning is an antiviral drug extracted from Andrographis paniculata extract. It is suitable for viral pneumonia and viral upper respiratory tract infection. During the production and processing of Yanhuning, the extract needs to be separated into solid and liquid to make the final product.

[0003] CN219646874U, "A solid-liquid separation device for the production of inflammatory oxaline" discloses: A solid-liquid separation device for the production of inflammatory oxaline, including an equipment body, the bottom of the equipment body is fixedly connected with a support column, the outside of the equipment body is fixedly installed with a controller, the top of the equipment body is fixedly connected with a liquid inlet hopper, the inside of the equipment body is movably connected with a running box, the outside of the running box is fixedly connected with a moving plate, the outside of the moving plate is fixedly connected with a handle, the inside of the running box is provided with a leak hole, the outside of the running box is fixedly connected with a reset spring, the top of the running box is fixedly connected with an L-shaped rod, the top of the L-shaped rod is fixedly connected with an extrusion cover, and the inside of the equipment body is fixedly connected with a connecting plate. The utility model is easy to use, can make solids and liquids quickly separated, and can make solids air-dried in time. The solid-liquid separation device of this patent only screens solids and liquids through a running box with a leak hole, and cannot continuously separate a large number of extracts, and the separation efficiency is low.

[0004] CN113663396B, "A solid-liquid high-speed separation of Yanhuning injection production screening equipment" discloses: A solid-liquid high-speed separation of Yanhuning injection production screening equipment, including a shell and a top cover, a rotating disk is movably installed in the bottom of the shell, a filter cartridge is fixedly installed at the edge of the top of the rotating disk, a connecting ring is fixedly installed on the inner side of the top of the filter cartridge, the top cover is installed on the top of the shell by bolts, and a mounting bearing is fixedly installed at the bottom of the top cover. The solid-liquid high-speed separation of Yanhuning injection production screening equipment is reasonably designed, when the rotating disk and the filter cartridge rotate, the spiral conveying rod can be driven to rotate synchronously, and the spiral conveying rod can actively convey the raw material downward through the addition pipe, and the faster the filter cartridge rotates, the faster the solid-liquid separation speed is, and the faster the raw material supply speed is, so that the amount of raw materials in the filter cartridge is kept within a suitable range, and then the solid-liquid separation speed is always kept high efficiency. This patent adopts a filter cartridge for separation by centrifugation, but its separation method is single, and the separation effect of the extract is not significantly improved.

[0005] Therefore, the solid-liquid separation of indomethacin requires an indomethacin solid-liquid separation device that is suitable for industrial production, can continuously separate the solid and liquid of a large amount of extracts, and has a high separation efficiency. Utility Model Content

[0006] The purpose of the utility model is to solve the problem that the current solid-liquid separation of indole is unable to achieve continuous solid-liquid separation of a large amount of extracts and has a higher separation efficiency, and to provide an indole solid-liquid separation device.

[0007] The utility model discloses a solid-liquid separation device for yanhuning, which comprises a separation box, a filter cylinder, a collection cylinder, a liquid storage box, a medicine residue collection box and a filter screen;

[0008] The separation box is composed of a separation area and a filtration area, and the separation area and the filtration area are connected through a material through hole; a filter cartridge and a collecting cartridge are arranged in the separation area; a filter cartridge is arranged in the collecting cartridge, one end face of the filter cartridge is fixed to the inner wall of the separation box through a rotating shaft, and the other end face is connected to the transmission shaft of a motor arranged outside the separation box; a plurality of liquid phase outlets are opened on the cylinder wall of the filter cartridge, a plurality of arc-shaped baffle plates are arranged circumferentially on the inner wall of the collecting cartridge, a plurality of water holes are opened on the arc-shaped baffle plates, an arc-shaped liquid drainage plate is arranged behind the arc-shaped baffle plate, the arc-shaped liquid drainage plate away from the opening of the collecting cartridge is in contact with the end of the arc-shaped baffle plate, and the arc-shaped liquid drainage plate close to the opening of the collecting cartridge is away from the end of the arc-shaped baffle plate; one end of the collecting cartridge is open, and the opening The mouth faces the filtration area, and the collecting cylinder opening is connected with the material through hole; the collecting cylinder is arranged on the supporting roller transmission system, and the supporting roller transmission system is composed of a supporting roller, a frame, a motor pulley and a belt; the collecting cylinder is arranged on the supporting roller, the supporting roller is installed on the frame, and the supporting roller is connected with the motor pulley through a belt; the feed port of the filter cylinder is connected with the feed hopper through a pipeline, and the discharge port of the filter cylinder is connected with the feed port of the slag suction machine through a pipeline, and the discharge port of the slag suction machine is connected with the feed port of the residue collection box; a filter screen and a liquid storage tank are arranged in the filtration area, one end of the filter screen is installed on the inner wall of the filtration area close to the material through hole, and the other end is installed on the inner wall of the filtration area opposite to the material through hole, and a solid phase discharge port is opened on the top, and the filtration area is connected with the residue collection box through the solid phase discharge port.

[0009] The utility model has the following beneficial effects:

[0010] The filter cartridge and collecting cartridge provided in the utility model can significantly improve the filtering efficiency of the filter screen and prevent the problem of a large amount of solid phase and liquid phase accumulating on the filter screen. The device of the utility model can realize the solid-liquid separation of a large amount of inflammatory oxaline extract for a long time and is suitable for large-scale industrial production. BRIEF DESCRIPTION OF THE DRAWINGS

[0011] Figure 1 It is a schematic diagram of the structure of the utility model;

[0012] Figure 2This is a schematic diagram of the filter cartridge, collecting cartridge and supporting wheel transmission system of the utility model;

[0013] Figure 3 It is a schematic diagram of an arc-shaped baffle plate, an arc-shaped liquid drainage plate, and a water hole. DETAILED DESCRIPTION

[0014] In order to make the objectives, technical solutions and advantages of the embodiments of the present invention more clearly understood, the spirit of the contents disclosed by the present invention will be described in detail below. After understanding the embodiments of the contents of the present invention, any technician in the relevant technical field can change and modify them according to the techniques taught by the contents of the present invention without departing from the spirit and scope of the contents of the present invention.

[0015] The exemplary embodiments of the present invention and the description thereof are used to explain the present invention but are not intended to limit the present invention.

[0016] Specific implementation method 1: This implementation method is described in conjunction with the figure. This implementation method is a solid-liquid separation device of Yanhuning, which includes a separation box 1, a filter cylinder 2, a collection cylinder 3, a liquid storage box 4, a drug residue collection box 5 and a filter screen 6;

[0017] The separation box 1 is composed of a separation area 111 and a filtration area 112, and the separation area 111 is connected to the filtration area 112 through a material through hole 113; a filter cartridge 2 and a collecting cartridge 3 are arranged in the separation area 111; a filter cartridge 2 is arranged in the collecting cartridge 3, one end face of the filter cartridge 2 is fixed to the inner wall of the separation box 1 through a rotating shaft, and the other end face is connected to the transmission shaft of the motor 7 arranged outside the separation box 1; a plurality of liquid phase outlets 21 are opened on the cylinder wall of the filter cartridge 2, a plurality of arc-shaped baffle plates 31 are arranged on the inner wall of the collecting cartridge 3 along the circumferential direction, a plurality of water holes 32 are opened on the arc-shaped baffle plates 31, and an arc-shaped liquid drainage plate 33 is arranged behind the arc-shaped baffle plate 31, and the arc-shaped liquid drainage plate 33 away from the opening of the collecting cartridge 3 is in contact with the end of the arc-shaped baffle plate 31, and the arc-shaped liquid drainage plate 33 close to the opening of the collecting cartridge 3 is away from the end of the arc-shaped baffle plate 31; one end of the collecting cartridge 3 is open, and the opening faces Towards the filtering area 112, and the collecting cylinder 3 opening is connected to the material through hole 113; the collecting cylinder 3 is arranged on the supporting roller transmission system, and the supporting roller transmission system is composed of a supporting roller 9, a frame 10, a motor pulley 11 and a belt 12; the collecting cylinder 3 is arranged on the supporting roller 9, the supporting roller 9 is installed on the frame 10, and the supporting roller is connected to the motor pulley 11 through the belt 12; the feed port of the filter cylinder 2 is connected to the feed hopper 8 through a pipeline, and the discharge port of the filter cylinder 2 is connected to the The feed port of the residue suction machine 20 is connected, and the discharge port of the residue suction machine 20 is connected to the feed port of the residue collection box 5; a filter screen 6 and a liquid storage tank 4 are arranged in the filtering area 112, one end of the filter screen 6 is installed on the inner wall of the filtering area 112 near the material through hole 113, and the other end is installed on the inner wall of the filtering area 112 opposite to the material through hole 113, and a solid phase discharge port 14 is opened on the top, and the filtering area 112 is connected to the residue collection box 5 through the solid phase discharge port 14.

[0018] The transmission shaft of the motor 7 of this embodiment passes through the filter cylinder 2 and the collecting cylinder 3 and is connected to the motor 7 .

[0019] The present utility model device is aimed at the traditional filter cartridge in centrifugal filtration, in which some solid phases are often mixed in the liquid phase separation, and a filter screen is usually used for further separation. However, in industrial production, the amount of indigofera extract that needs to be separated is large. Due to the long separation time, a large amount of solid phase and liquid phase will need to be filtered through the filter screen, which reduces the filtration efficiency. In order to prevent a large amount of solid phase and liquid phase from accumulating on the filter screen and reducing the filtration efficiency, the present utility model utilizes the combined effect of the filter cartridge 2 and the collecting cartridge 3 to collect the liquid phase and the mixture mixed with a small amount of solid phase filtered out by the filter cartridge 2 of the indigofera extract entering from the feed hopper 8 through the collecting cartridge 3. The long arc-shaped baffle plate 31 arranged along the length of the collecting cartridge 3 will collect the mixture. Since the rotation direction of the collecting cartridge 3 is the same as the concave surface of the arc-shaped baffle plate 31, the collected mixture will be fixed in the arc-shaped baffle plate 31 by centrifugal force, and the water holes on the arc-shaped baffle plate 31 can be adjusted. 32 size, the residue is retained in the arc-shaped baffle plate 31 as much as possible, the liquid flows out from the water hole 32 to the arc-shaped liquid drainage plate 33, the inner concave surface of the arc-shaped liquid drainage plate 33 is in the same direction as the inner concave surface of the arc-shaped baffle plate 31, so that the outflowing liquid can be collected, and the arc-shaped liquid drainage plate 33 is tilted, that is, the arc-shaped baffle plate 31 and the end face of the opening of the collecting tube 3 can be vertically arranged, and the arc-shaped drainage plate 33 and the end face of the opening of the collecting tube 3 can be tilted. Under the action of centrifugation, the collected liquid can be thrown out from the opening of the collecting tube 3, and the separation situation can be observed at any time using the observation window 15. The areas of the arc-shaped baffle plate 31 and the arc-shaped guide plate 33 can be adjusted according to actual production; when the collecting tube 3 stops rotating, since the opening of the collecting tube 3 is larger than the bottom, the size of the opening is adjusted according to actual production, and the solid phase in the collecting tube 3 will flow out from the opening to the filter screen 6, and the remaining liquid will be filtered through the filter screen 6, and the solid phase will enter the drug residue collection box 5 through the material through hole 113. The above method can prevent a large amount of solid phase and liquid phase from accumulating on the filter screen 6 and reducing the filtering efficiency.

[0020] Specific embodiment 2: This embodiment is described with reference to the figures. The difference between this embodiment and specific embodiment 1 is that a drainage platform 16 is provided at the bottom of the material through hole 113 .

[0021] The rest is the same as the first specific implementation mode.

[0022] Specific implementation method three: This implementation method is described in conjunction with the figures. The difference between this implementation method and specific implementation method one is that the drainage platform 16 is a right-angled triangle structure, the drainage platform 16 of the triangle structure has its hypotenuse facing upward and its short side facing the outlet of the collecting tube 3.

[0023] The rest is the same as the first specific implementation mode.

[0024] Specific embodiment 4: This embodiment is described with reference to the figures. The difference between this embodiment and specific embodiment 1 is that the filter cartridge 2 and the collecting cartridge 3 are both placed horizontally in the separation box 1.

[0025] The rest is the same as the first specific implementation mode.

[0026] Specific embodiment 5: This embodiment is described with reference to the figures. The difference between this embodiment and specific embodiment 1 is that a filter screen is provided on the liquid phase outlet 21 .

[0027] The rest is the same as the first specific implementation mode.

[0028] Specific embodiment 6: This embodiment is described with reference to the figures. The difference between this embodiment and specific embodiment 1 is that an observation window 15 is provided on the filtering area 112 .

[0029] The rest is the same as the first specific implementation mode.

[0030] Specific embodiment 7: This embodiment is described with reference to the figures. The difference between this embodiment and specific embodiment 1 is that the drug residue collection box 5 is provided with a box door 51.

[0031] The rest is the same as the first specific implementation mode.

[0032] Specific embodiment eight: This embodiment is described with reference to the figures. The difference between this embodiment and specific embodiment one is that a liquid outlet pipe 41 is provided at the bottom of the liquid storage tank 4 .

[0033] Other components and connection methods are the same as those in the first embodiment.

[0034] Specific embodiment 9: This embodiment is described with reference to the figures. The difference between this embodiment and specific embodiment 1 is that the inner concave part of the arc-shaped baffle plate 31 faces the rotation direction of the collecting tube 3.

[0035] The rest is the same as the first specific implementation mode.

[0036] Specific embodiment ten: This embodiment is described with reference to the figures. The difference between this embodiment and specific embodiment one is that the diameter of the opening of the collecting tube 3 is greater than the diameter of the bottom of the collecting tube 3 .

[0037] Other components and connection methods are the same as those in the first embodiment.

Claims

1. A solid-liquid separation device for linalool, characterized in that It comprises a separation box (1), a filter cylinder (2), a collecting cylinder (3), a liquid storage box (4), a medicine residue collection box (5) and a filter screen (6); The separation box (1) is composed of a separation area (111) and a filtration area (112), and the separation area (111) and the filtration area (112) are connected through a material through hole (113); a filter cartridge (2) and a collecting cartridge (3) are arranged in the separation area (111); a filter cartridge (2) is arranged in the collecting cartridge (3), one end face of the filter cartridge (2) is fixed to the inner wall of the separation box (1) through a rotating shaft, and the other end face is connected to the transmission shaft of a motor (7) arranged outside the separation box (1); a plurality of liquid phase outlet ports are opened on the wall of the filter cartridge (2) The collecting tube (3) has an inner wall provided with a plurality of arc-shaped baffle plates (31) along the circumferential direction, the arc-shaped baffle plates (31) are provided with a plurality of water holes (32), an arc-shaped liquid drainage plate (33) is provided behind the arc-shaped baffle plates (31), the arc-shaped liquid drainage plate (33) away from the opening of the collecting tube (3) is in contact with the end of the arc-shaped baffle plate (31), and the arc-shaped liquid drainage plate (33) close to the opening of the collecting tube (3) is away from the end of the arc-shaped baffle plate (31); one end of the collecting tube (3) is open, and the opening faces the water-passing opening. The filter area (112) is provided, and the opening of the collecting cylinder (3) is connected to the material through hole (113); the collecting cylinder (3) is arranged on a supporting roller transmission system, and the supporting roller transmission system is composed of a supporting roller (9), a frame (10), a motor pulley (11) and a belt (12); the collecting cylinder (3) is arranged on the supporting roller (9), the supporting roller (9) is installed on the frame (10), and the supporting roller is connected to the motor pulley (11) through the belt (12); the feed port of the filter cylinder (2) is connected to the feed hopper (8) through a pipeline, and the discharge port of the filter cylinder (2) is connected to the feed hopper (8) through a pipeline. The filter (112) is connected to the feed port of the residue suction machine (20), and the discharge port of the residue suction machine (20) is connected to the feed port of the residue collection box (5); a filter screen (6) and a liquid storage box (4) are arranged in the filter area (112); one end of the filter screen (6) is installed on the inner wall of the filter area (112) near the material through hole (113), and the other end is installed on the inner wall of the filter area (112) opposite to the material through hole (113), and a solid phase discharge port (14) is opened on the top, and the filter area (112) is connected to the residue collection box (5) through the solid phase discharge port (14).

2. A solid-liquid separation device for linalool according to claim 1, characterized in that A drainage platform (16) is provided at the bottom of the material through hole (113).

3. A solid-liquid separation device for linalool according to claim 2, characterized in that The drainage platform (16) is a right-angled triangle structure, the hypotenuse of the drainage platform (16) of the triangle structure faces upward, and the short side faces the outlet of the collecting tube (3).

4. The solid-liquid separation device of claim 1, characterized in that The filter cylinder (2) and the collecting cylinder (3) are both placed horizontally in the separation box (1).

5. The solid-liquid separation device of yanhuning according to claim 1 is characterized in that The liquid phase outlet (21) is provided with a filter screen.

6. The solid-liquid separation device of yanhuning according to claim 1, characterized in that An observation window (15) is provided on the filtering area (112).

7. The solid-liquid separation device of yanhuning according to claim 1 is characterized in that The medicinal residue collection box (5) is provided with a box door (51).

8. The solid-liquid separation device of yanhuning according to claim 1 is characterized in that A liquid outlet pipe (41) is provided at the bottom of the liquid storage tank (4).

9. The solid-liquid separation device of yanhuning according to claim 1, characterized in that The inner concave part of the arc-shaped baffle plate (31) faces the rotation direction of the collecting cylinder (3).

10. The solid-liquid separation device of yanhuning according to claim 1, characterized in that The diameter of the opening of the collecting tube (3) is larger than the diameter of the bottom of the collecting tube (3).

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