Helicobacter pylori immunofluorescence quantitative detection kit
By designing a movable plate system with torsion spring in the Helicobacter pylori immunofluorescence quantitative detection kit, the reagent bottle shaking up and down, the problem of slow mixing of fluorescent labeled immune complexes and Helicobacter pylori antigens is solved, and the detection efficiency is improved .
Patent Information
- Application Number
- CN202420630024.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-03-29
- Publication Date
- 2025-02-25
- Estimated Expiration
- 2034-03-29
AI Technical Summary
In the existing Helicobacter pylori immunofluorescence quantitative detection kit, the fluorescently labeled immune complex and Helicobacter pylori antigen are slow to mix themselves, resulting in low detection efficiency.
A Helicobacter pylori immunofluorescence quantitative detection kit was designed. By rotating the rotating rod, the gears and racks are rotated, and then the top rod on the movable plate is moved upward. After loosening, the torsion spring drives the movable plate to rebound, so that the reagent bottle is Sway up and down, thereby increasing the mixing speed of the fluorescently labeled immune complex with Helicobacter pylori antigen.
Through the above design, the mixing speed of fluorescently labeled immune complexes and Helicobacter pylori antigens is significantly improved, thereby improving the detection efficiency and meeting the needs of users.
Smart Images

Figure CN222529366U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of detection kits, in particular to a Helicobacter pylori immunofluorescence quantitative detection kit. Background Art
[0002] Helicobacter pylori is a common stomach bacterium that is associated with digestive system diseases such as gastritis, peptic ulcer and gastric cancer. In order to accurately diagnose and treat these diseases, efficient and accurate detection methods are needed, among which the Helicobacter pylori immunofluorescence quantitative detection kit is a commonly used detection tool.
[0003] After searching, the Chinese patent announcement number: CN215362509U discloses a Helicobacter pylori immunofluorescence quantitative detection kit, including a box body, the box body is hinged with a box cover, a plurality of placement circular grooves are opened on the upper end of the box body, and springs, pads and support seats are sequentially assembled inside the circular grooves from bottom to top, the pads are rotatably connected to the support seats, and an annular groove is opened on the upper inner side of the placement circular groove, and a first limiting groove that penetrates the upper end of the box body is provided on the front and rear sides of the upper end of the annular groove, and a second limiting groove that does not penetrate the upper end of the box body is provided on the left and right sides of the upper end of the annular groove, and a reagent bottle for storing detection reagents is placed in the placement circular groove, and limit blocks are provided on the left and right sides of the reagent bottle. The reagent test kit can store the reagent bottle and fix the reagent bottle at the same time to prevent it from moving at will and avoid the reagent bottle from being damaged. In addition, the reagent test kit is convenient for users to take out the reagent bottle. However, the device only places the reagent bottle into the placement slot, and then performs detection by self-mixing the fluorescently labeled immune complex with the Helicobacter pylori antigen. Since the self-mixing speed of the fluorescently labeled immune complex and the Helicobacter pylori antigen is slow, the detection efficiency is reduced and cannot meet the needs of users. Utility Model Content
[0004] In order to make up for the above shortcomings, the utility model provides a Helicobacter pylori immunofluorescence quantitative detection kit, aiming to improve the problem of slow self-mixing speed of fluorescent labeled immune complex and Helicobacter pylori antigen in the prior art Helicobacter pylori immunofluorescence quantitative detection kit.
[0005] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a Helicobacter pylori immunofluorescence quantitative detection kit comprises a box body, a fixed block is fixedly connected to the inside of the box body, a plurality of placement holes are equidistantly provided on the top of the fixed block, a rotating rod is rotatably connected to the left side of the box body, a gear is fixedly connected to the middle part of the outer side of the rotating rod, grooves are provided on the left and right sides of the inside of the box body, the same movable plate is slidably connected to the inside of the two grooves, a rack is fixedly connected to the bottom of the movable plate, the rack is meshed with the gear, a fixed plate is fixedly connected to the left side of the outer wall of the rotating rod, torsion springs are provided on the left and right ends of the outer wall of the rotating rod, one end of the torsion spring is fixedly connected to the fixed plate, and the other end of the torsion spring is fixedly connected to the right side of the inside of the box body, a plurality of push rods are equidistantly fixedly connected to the top of the movable plate, the top ends of the plurality of push rods respectively pass through the corresponding placement holes and are fixedly connected to the placement grooves, and a sterilization mechanism is provided on the top of the box body.
[0006] As a further description of the above technical solution:
[0007] The sterilization mechanism includes a box cover, which is arranged on the top of the box body, and an open groove is opened at the bottom of the box cover. A micro motor is fixedly connected to the right side of the opening groove, and a screw rod is fixedly connected to the output end of the micro motor. The outer side of the screw rod is threadedly connected to a movable block, and the bottom of the movable block is fixedly connected to an ultraviolet disinfection lamp. The front and rear sides of the ultraviolet disinfection lamp are fixedly connected to batteries, and the battery is electrically connected to the ultraviolet disinfection lamp.
[0008] As a further description of the above technical solution:
[0009] A reagent bottle is arranged inside the placement hole, and first limiting grooves are opened on the left and right sides of the interiors of multiple placement holes, and sliders are fixedly connected to the left and right sides of multiple reagent bottles, and multiple sliders are respectively slidably connected to the corresponding first limiting grooves. An annular groove is opened in the middle and upper part of the inner side of the placement hole, and multiple sliders are respectively slidably connected to the corresponding annular grooves. Second limiting grooves are opened on the front and rear sides of multiple placement holes, and multiple sliders are respectively slidably connected to the corresponding second limiting grooves.
[0010] As a further description of the above technical solution:
[0011] The right side of the box body is fixedly connected with a controller, and the controller is electrically connected with the micro motor and the battery respectively.
[0012] As a further description of the above technical solution:
[0013] A protective cover is arranged on the outer side of the controller, and one side of the protective cover is rotatably connected to the right side of the box body.
[0014] As a further description of the above technical solution:
[0015] The sterilization mechanism also includes a rotating shaft, and the two rotating shafts are respectively arranged on the left and right sides of the rear end of the box cover. The box cover is rotatably connected to the left and right ends of the rear side of the box body through the rotating shafts, and the left and right sides of the front end of the box cover are both provided with locking structures.
[0016] As a further description of the above technical solution:
[0017] The movable block is slidably connected to the inside of the opening groove.
[0018] As a further description of the above technical solution:
[0019] The sterilization mechanism also includes a handle, which is fixedly connected to the middle part of the top end of the box cover.
[0020] The utility model has the following beneficial effects:
[0021] 1. In the utility model, rotating the rotating rod can drive the gear to rotate, and the rack will rotate accordingly, thereby driving the top rod on the movable plate to move upward, and then releasing the rotating rod. At this time, the torsion spring will drive the movable plate to rebound through its own elastic potential energy. Repeating the above operation can drive the reagent bottle in the placement hole to shake up and down, thereby increasing the mixing speed of the fluorescent labeled immune complex and the Helicobacter pylori antigen, thereby improving the detection efficiency and meeting the needs of users.
[0022] 2. In the utility model, the micro motor can drive the screw to rotate, and the movable block on the screw will drive the ultraviolet disinfection lamp to move left and right. At the same time, the ultraviolet disinfection lamp can be started to disinfect the inside of the box body, and the inside of the reagent bottle is not easily infected by bacteria, thereby improving the practicality of the device. BRIEF DESCRIPTION OF THE DRAWINGS
[0023] Figure 1 A three-dimensional diagram of the Helicobacter pylori immunofluorescence quantitative detection kit proposed by the utility model;
[0024] Figure 2 It is a partial structural cross-sectional view of the Helicobacter pylori immunofluorescence quantitative detection kit proposed by the utility model;
[0025] Figure 3 This is a cross-sectional view of the fixed block structure of the Helicobacter pylori immunofluorescence quantitative detection kit proposed by the utility model;
[0026] Figure 4 The utility model provides a schematic diagram of the structure of the sterilization mechanism of the Helicobacter pylori immunofluorescence quantitative detection kit.
[0027] Legend:
[0028] 1. Box body; 2. Sterilization mechanism; 201. Box cover; 202. Opening slot; 203. Micro motor; 204. Screw rod; 205. Movable block; 206. Ultraviolet disinfection lamp; 207. Battery; 208. Rotating shaft; 209. Locking structure; 210. Handle; 3. Fixed block; 4. Placement hole; 5. Rotating rod; 6. Gear; 7. Rack; 8. Groove; 9. Movable plate; 10. Fixed plate; 11. Torsion spring; 12. Push rod; 13. Placement slot; 14. Reagent bottle; 15. First limit slot; 16. Sliding block; 17. Annular slot; 18. Second limit slot; 19. Controller; 20. Protective cover. DETAILED DESCRIPTION
[0029] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0030] Reference Figure 1 , Figure 2 and Figure 3 , an embodiment provided by the utility model: a Helicobacter pylori immunofluorescence quantitative detection kit, comprising a box body 1, a fixed block 3 is fixedly connected inside the box body 1, a plurality of placement holes 4 are equidistantly provided on the top of the fixed block 3, a rotating rod 5 is rotatably connected to the left side of the box body 1, a gear 6 is fixedly connected to the middle part of the outer side of the rotating rod 5, grooves 8 are provided on the left and right sides of the interior of the box body 1, the same movable plate 9 is slidably connected inside the two grooves 8, a rack 7 is fixedly connected to the bottom of the movable plate 9, the rack 7 is meshed with the gear 6, a fixed plate 10 is fixedly connected to the left side of the outer wall of the rotating rod 5, a torsion spring 11 is provided on the left and right ends of the outer wall of the rotating rod 5, one end of the torsion spring 11 is fixedly connected to the fixed plate 10, and the other end of the torsion spring 11 is fixedly connected to the right side of the interior of the box body 1, a plurality of ejector rods 12 are equidistantly fixedly connected to the top of the movable plate 9, the top ends of the plurality of ejector rods 12 respectively penetrate the corresponding placement holes 4 and are fixedly connected to placement grooves 13, and a sterilization mechanism 2 is provided on the top of the box body 1;
[0031] Specifically, when the rotating rod 5 is rotated, the gear 6 will rotate accordingly. Since the gear 6 is meshed with the rack 7, the rack 7 can also follow the movement of the gear 6. This design cleverly transfers the rotational kinetic energy to the movable plate 9. The top rod 12 on the movable plate 9 is another key component. When the rack 7 drives the movable plate 9 to rotate, the top rod 12 will move upward due to inertia. There is a placement groove 13 at the top of the top rod 12, which can fix the reagent bottle 14. As the top rod 12 moves upward, the reagent bottle 14 will also rise accordingly. After completing the rising operation, the rotating rod 5 is released. At this time, the torsion spring 11 begins to play a role, and it uses its own elastic potential energy to drive the movable plate 9 to rebound. In this way, the reagent bottle 14 will move downward due to the tension of the spring. By repeating the above operation, the reagent bottle 14 will shake up and down in the placement hole 4. This shaking method can increase the mixing speed of the fluorescent labeled immune complex and the Helicobacter pylori antigen. The increase in mixing speed means an increase in detection efficiency, which can meet the needs of users.
[0032] Reference Figure 1 and Figure 4 The sterilization mechanism 2 includes a box cover 201, which is arranged on the top of the box body 1. An open slot 202 is provided at the bottom of the box cover 201. A micro motor 203 is fixedly connected to the right side of the open slot 202. A screw rod 204 is fixedly connected to the output end of the micro motor 203. A movable block 205 is threadedly connected to the outer side of the screw rod 204. An ultraviolet disinfection lamp 206 is fixedly connected to the bottom of the movable block 205. A battery 207 is fixedly connected to the front and rear sides of the ultraviolet disinfection lamp 206. The battery 207 is electrically connected to the ultraviolet disinfection lamp 206. The movable block 205 is slidably connected to the inside of the open slot 202.
[0033] Specifically, in the process of frequently opening the box cover 201, external germs may enter the box body 1. At this time, the micro motor 203 can drive the screw rod 204 to rotate, and the movable block 205 will also move accordingly, thereby driving the ultraviolet disinfection lamp 206 to move left and right. At the same time, the ultraviolet disinfection lamp 206 can emit strong ultraviolet rays to disinfect the inside of the box body 1, which can not only effectively prevent external germs from entering the box body 1, but also disinfect the inside of the box body 1 when necessary, ensuring that the reagent bottle 14 is not invaded by germs. In this way, the reagent bottle 14 inside the box body 1 can always be kept clean and hygienic, ensuring the accuracy of the experimental results.
[0034] Reference Figure 3, a reagent bottle 14 is arranged inside the placement hole 4, a first limiting groove 15 is provided on the left and right sides of the interiors of the plurality of placement holes 4, a slider 16 is fixedly connected to the left and right sides of the plurality of reagent bottles 14, and the plurality of sliders 16 are respectively slidably connected to the corresponding first limiting groove 15, an annular groove 17 is provided in the middle and upper part of the inner side of the placement hole 4, and the plurality of sliders 16 are respectively slidably connected to the corresponding annular groove 17, and a second limiting groove 18 is provided on the front and rear sides of the plurality of placement holes 4, and the plurality of sliders 16 are respectively slidably connected to the corresponding second limiting groove 18;
[0035] Specifically, first place the reagent bottle 14 in the placement hole 4, then rotate the reagent bottle 14 so that the slider 16 on its outside enters the annular groove 17, and then continue to rotate so that the slider 16 enters the first limiting groove 15. The reagent bottle 14 can be limited in position, and the reagent bottle 14 will not easily fall over during transportation, thereby improving the practicality of the device.
[0036] Reference Figure 1 The right side of the box body 1 is fixedly connected with a controller 19, and the controller 19 is electrically connected with the micro motor 203 and the battery 207 respectively. A protective cover 20 is arranged outside the controller 19, and one side of the protective cover 20 is rotatably connected with the right side of the box body 1;
[0037] Specifically, the operation of the micro motor 203 and the battery 207 can be controlled by the controller 19, and the protective cover 20 can protect the controller 19 from being damaged by external factors.
[0038] Reference Figure 1 and Figure 4 The sterilization mechanism 2 further includes a rotating shaft 208, and the two rotating shafts 208 are respectively arranged at the left and right sides of the rear end of the box cover 201. The box cover 201 is rotatably connected to the left and right ends of the rear side of the box body 1 through the rotating shaft 208. The left and right sides of the front end of the box cover 201 are both provided with a locking structure 209. The sterilization mechanism 2 further includes a handle 210, and the handle 210 is fixedly connected to the middle part of the top end of the box cover 201;
[0039] Specifically, the box cover 201 can be opened through the locking structure 209 to facilitate the user to take out the reagent bottle 14, and the handle 210 can facilitate the user to carry the box body 1.
[0040] Working principle: When using the reagent kit, first open the box cover 201 and then place the reagent bottles 14 into the placement grooves 13 inside the corresponding placement holes 4, and then rotate the reagent bottle 14 so that the slider 16 on its outside enters the second limit groove 18 from the first limit groove 15, which can improve the safety of transporting the reagent bottle 14, and then close the box cover 201, and then rotate the rotating rod 5 to drive the gear 6 to rotate, and the rack 7 will also rotate due to the engagement with the gear 6, so as to drive the push rod 12 on the movable plate 9 to move upward, and the placement groove 13 at the top of the push rod 12 will drive the reagent bottle 14 to move upward, and then release the rotating rod 5. At this time, the torsion spring 11 will use its own elastic potential energy The movable plate 9 is driven to rebound, and repeating the above operation can drive the reagent bottle 14 in the placement hole 4 to shake up and down, thereby increasing the mixing speed of the fluorescent-labeled immune complex and the Helicobacter pylori antigen, thereby improving the detection efficiency and meeting the needs of users. In addition, since the box cover 201 is frequently opened, external pathogens can easily enter the box body 1. At this time, the micro motor 203 can drive the screw rod 204 to rotate, and the movable block 205 on the screw rod 204 will drive the ultraviolet disinfection lamp 206 to move left and right. At the same time, starting the ultraviolet disinfection lamp 206 can disinfect the inside of the box body 1, and the inside of the reagent bottle 14 is not easily infected with pathogens, thereby improving the practicality of the device.
[0041] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.
Claims
1. A Helicobacter pylori immunofluorescence quantitative detection kit, comprising a box body (1), characterized in that: The box body (1) is fixedly connected with a fixed block (3) inside, and a plurality of placement holes (4) are equidistantly provided on the top of the fixed block (3). The left side of the box body (1) is rotatably connected with a rotating rod (5), and a gear (6) is fixedly connected to the middle of the outer side of the rotating rod (5). The box body (1) is provided with grooves (8) on both the left and right sides inside, and the insides of the two grooves (8) are slidably connected with the same movable plate (9). The bottom of the movable plate (9) is fixedly connected with a rack (7), and the rack (7) is meshed with the gear (6). The rotating rod (5) A fixed plate (10) is fixedly connected to the left side of the outer wall of the rotating rod (5); torsion springs (11) are arranged at the left and right ends of the outer wall of the rotating rod (5); one end of the torsion spring (11) is fixedly connected to the fixed plate (10); the other end of the torsion spring (11) is fixedly connected to the right side of the inside of the box body (1); a plurality of push rods (12) are fixedly connected to the top of the movable plate (9) at equal intervals; the top ends of the plurality of push rods (12) respectively penetrate the corresponding placement holes (4) and are fixedly connected to the placement grooves (13); a sterilization mechanism (2) is arranged on the top of the box body (1).
2. The Helicobacter pylori immunofluorescence quantitative detection kit according to claim 1, characterized in that: The sterilization mechanism (2) comprises a box cover (201), wherein the box cover (201) is arranged on the top of the box body (1), and an open groove (202) is provided at the bottom of the box cover (201), a micro motor (203) is fixedly connected to the right side of the inside of the open groove (202), a screw rod (204) is fixedly connected to the output end of the micro motor (203), a movable block (205) is threadedly connected to the outer side of the screw rod (204), an ultraviolet disinfection lamp (206) is fixedly connected to the bottom of the movable block (205), and a storage battery (207) is fixedly connected to the front and rear sides of the ultraviolet disinfection lamp (206), and the storage battery (207) is electrically connected to the ultraviolet disinfection lamp (206).
3. The Helicobacter pylori immunofluorescence quantitative detection kit according to claim 1, characterized in that: A reagent bottle (14) is arranged inside the placement hole (4), and first limiting grooves (15) are provided on the left and right sides of the interiors of the plurality of placement holes (4). Slide blocks (16) are fixedly connected to the left and right sides of the plurality of reagent bottles (14), and the plurality of slide blocks (16) are respectively slidably connected to the interiors of the corresponding first limiting grooves (15). An annular groove (17) is provided in the middle and upper part of the inner side of the placement hole (4), and the plurality of slide blocks (16) are respectively slidably connected to the interiors of the corresponding annular grooves (17). Second limiting grooves (18) are provided on the front and rear sides of the plurality of placement holes (4), and the plurality of slide blocks (16) are respectively slidably connected to the interiors of the corresponding second limiting grooves (18).
4. The Helicobacter pylori immunofluorescence quantitative detection kit according to claim 1, characterized in that: A controller (19) is fixedly connected to the right side of the box body (1), and the controller (19) is electrically connected to the micro motor (203) and the storage battery (207) respectively.
5. The Helicobacter pylori immunofluorescence quantitative detection kit according to claim 4, characterized in that: A protective cover (20) is arranged on the outside of the controller (19), and one side of the protective cover (20) is rotatably connected to the right side of the box body (1).
6. The Helicobacter pylori immunofluorescence quantitative detection kit according to claim 2, characterized in that: The sterilization mechanism (2) further comprises a rotating shaft (208), wherein two rotating shafts (208) are respectively arranged on the left and right sides of the rear end of the box cover (201), and the box cover (201) is rotatably connected to the left and right ends of the rear side of the box body (1) via the rotating shafts (208), and locking structures (209) are arranged on the left and right sides of the front end of the box cover (201).
7. The Helicobacter pylori immunofluorescence quantitative detection kit according to claim 2, characterized in that: The movable block (205) is slidably connected to the inside of the opening groove (202).
8. The Helicobacter pylori immunofluorescence quantitative detection kit according to claim 2, characterized in that: The sterilization mechanism (2) further comprises a handle (210), and the handle (210) is fixedly connected to the middle part of the top end of the box cover (201).
Citation Information
Patent Citations
Helicobacter pylori immunofluorescence quantitative detection kit
CN215362509U