Refining device for synthesizing phenylbutazone

Abstract

The utility model belongs to the field of preparation process of penctazone, and particularly relates to a refining device for synthesis of penctazone, which comprises a bottom plate, a water bath heater is fixedly arranged on the surface of the bottom plate, a water changing pipe is fixedly connected to the outer wall of the water bath heater, and a storage barrel is tightly attached to the inner wall of the water bath heater. A cover plate is fixedly mounted at the top of the storage barrel; through the structural design that the air pressure in the storage barrel is reduced through the sucking pump, the water bath heater is filled with hot water through the water changing pipe, meanwhile, the motor is started through an external power source, and the motor drives the stirring blades to work through the gear set and the rotating shaft, the reaction efficiency of the device is improved, solid-liquid separation is achieved through the condensation barrel, and the production efficiency of the device is improved; and secondly, through the structural design that the first valve and the second valve on one side are closed, the mounting cover is disassembled, the interior of the device is cleaned, and the condensation barrel on the other side continues to work, the device can continue to work during cleaning and maintenance, and the cleanliness and adaptability of the device are improved.

Description

Technical Field

[0001] The utility model relates to the field of phenylbutazone preparation technology, in particular to a refining device used for phenylbutazone synthesis. Background Art

[0002] Phenylbutazone is a hormone drug with miraculous anti-inflammatory and analgesic effects, especially for aseptic inflammation, such as rheumatic pain, muscle pain, etc. The crude product of Phenylbutazone is obtained, and then the crude product is refined with medicinal ethanol to obtain the fine Phenylbutazone, and a large amount of wastewater is generated in this process.

[0003] The existing synthetic and refined drug preparation process is not efficient enough, and there may be a problem of low production efficiency. The existing synthetic and refined drug preparation process is not easy to achieve the effect of cleaning the equipment without interfering with the normal operation of the device, and there may be a problem of low cleanliness and adaptability of the device.

[0004] Therefore, in view of the above problems, a refining device for synthesizing phenylbutazone is proposed. Utility Model Content

[0005] In order to remedy the problems in the prior art, the utility model provides a refining device for synthesizing phenylbutazone.

[0006] The technical solution adopted by the utility model to solve its technical problems is: a refining device for the synthesis of phenylbutazone described in the utility model comprises a bottom plate, a water bath heater is fixedly arranged on the surface of the bottom plate, a water changing pipe is fixedly connected to the outer wall of the water bath heater, a storage barrel is tightly fitted to the inner wall of the water bath heater, a cover plate is fixedly installed on the top of the storage barrel, a feed pipe is fixedly connected above the cover plate, a top cover is snap-fitted on the top of the feed pipe, one end of a connecting pipe is fixedly connected to one side of the storage barrel, the other end of the connecting pipe is fixedly connected to a first valve, and one end of the first valve is fixedly connected to the surface of a condensation barrel.

[0007] Preferably, a mounting cover is mounted on the top of the condensing barrel, the top of the mounting cover is fixedly connected to a second valve, and the rear side of the second valve is fixedly connected to a water cooling box.

[0008] Preferably, a water pump is fixedly provided inside the water cooling box, a condenser is fixedly connected to the surface of the water pump, and one end of the condenser is fixedly connected to the condenser inside the condensation barrel via a second valve.

[0009] Preferably, a rotating shaft is provided through the interior of the cover plate, a stirring blade is fixedly connected to the bottom end of the rotating shaft, one side of a gear set is fixedly connected to the top end of the rotating shaft, and the other side of the gear set is fixedly connected to the output end of the motor.

[0010] Preferably, a drain valve is fixedly connected to the outer wall of the condensation barrel near the bottom, and the number of the condensation barrels and the number of the first valve and the second valve are both two.

[0011] Preferably, one end of the material storage barrel is fixedly connected to one end of an air extraction valve, and the other end of the air extraction valve is fixedly connected to an air extraction pump.

[0012] The utility model is beneficial in that:

[0013] 1. The utility model reduces the internal air pressure of the storage barrel through the vacuum pump, fills the water bath heater with hot water through the water exchange pipe, and starts the motor through the external power supply. The motor drives the stirring blades to work through the gear set and the rotating shaft, thereby improving the reaction efficiency of the device, realizing solid-liquid separation through the condensation barrel, and improving the production efficiency of the device;

[0014] 2. The utility model closes the first valve and the second valve on one side, removes the installation cover, cleans the inside of the device, and the condensation barrel on the other side continues to work. The structural design facilitates the device to continue working during cleaning and maintenance, thereby improving the cleanliness and adaptability of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0016] Figure 1 This is a schematic diagram of the structure of the water bath heater of the utility model;

[0017] Figure 2 This is a schematic diagram of the material storage barrel structure of the utility model;

[0018] Figure 3 This is a schematic diagram of the water cooling box structure of the utility model;

[0019] Figure 4 This is a schematic diagram of the structure of the liquid discharge valve of the utility model.

[0020] In the figure: 1, bottom plate; 2, water bath heater; 3, water exchange pipe; 4, storage barrel; 5, cover plate; 6, feed pipe; 61, top cover; 7, rotating shaft; 8, stirring blade; 9, gear set; 10, motor; 11, air extraction valve; 12, air extraction pump; 13, connecting pipe; 14, first valve; 15, condensation barrel; 151, installation cover; 16, drain valve; 17, second valve; 18, water cooling box; 19, water pump; 20, condensation pipe. DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0022] See also Figure 1-Figure 4 As shown, a refining device for the synthesis of phenylbutazone comprises a bottom plate 1, a water bath heater 2 is fixedly arranged on the surface of the bottom plate 1, a water changing pipe 3 is fixedly connected to the outer wall of the water bath heater 2, a storage barrel 4 is closely fitted to the inner wall of the water bath heater 2, a cover plate 5 is fixedly installed on the top of the storage barrel 4, a feed pipe 6 is fixedly connected above the cover plate 5, a top cover 61 is clamped and installed on the top of the feed pipe 6, one end of a connecting pipe 13 is fixedly connected to one side of the storage barrel 4, a first valve 14 is fixedly connected to the other end of the connecting pipe 13, and one end of the first valve 14 is fixedly connected to the surface of a condensation barrel 15;

[0023] Furthermore, a mounting cover 151 is mounted on the top of the condensation barrel 15, the top of the mounting cover 151 is fixedly connected to the second valve 17, and the rear side of the second valve 17 is fixedly connected to the water cooling box 18;

[0024] During operation, the top of the condensation barrel 15 is engaged with the mounting cover 151 , which is designed to facilitate disassembly of the device when cleaning the condensation barrel 15 .

[0025] Furthermore, a water pump 19 is fixedly arranged inside the water cooling box 18, a condenser pipe 20 is fixedly connected to the surface of the water pump 19, and one end of the condenser pipe 20 is fixedly connected to the condenser pipe 20 inside the condenser barrel 15 through the second valve 17;

[0026] During operation, a water pump 19 is fixedly provided inside the water cooling box 18 , and a condenser pipe 20 is fixedly connected to the surface of the water pump 19 , so as to facilitate cooling the inside of the condensation barrel 15 through the condenser pipe 20 .

[0027] Furthermore, a rotating shaft 7 is provided inside the cover plate 5, a stirring blade 8 is fixedly connected to the bottom end of the rotating shaft 7, a side of a gear set 9 is fixedly connected to the top end of the rotating shaft 7, and the other side of the gear set 9 is fixedly connected to the output end of the motor 10;

[0028] During operation, a stirring blade 8 is fixedly connected to the bottom of the rotating shaft 7, and the top of the rotating shaft 7 is connected to the motor 10 through a gear set 9, so as to automatically stir the raw materials in the storage barrel 4 and improve the automation efficiency of the device.

[0029] Furthermore, a drain valve 16 is fixedly connected to the outer wall of the condensation barrel 15 near the bottom, and the number of the condensation barrels 15 and the number of the first valves 14 and the second valves 17 are both two;

[0030] During operation, due to the structural design of the two condensation barrels 15, when one condensation barrel 15 is being cleaned, the other condensation barrel 15 is working normally, so that the device can continue to work.

[0031] Furthermore, one end of the storage barrel 4 is fixedly connected to one end of the air extraction valve 11, and the other end of the air extraction valve 11 is fixedly connected to the air extraction pump 12;

[0032] During operation, an exhaust valve 11 is connected to one end of the storage barrel 4, and the exhaust valve 11 is connected to an exhaust pump 12, so as to exhaust air and reduce the pressure inside the storage barrel 4, thereby improving the reaction efficiency of the device.

[0033] Working principle: In the process of synthesizing and refining phenylbutazone, firstly, the top cover 61 is opened, and the crude phenylbutazone raw material and medicinal ethanol are put into the storage barrel 4 through the feed pipe 6. At this time, the top cover 61 is closed, the air extraction valve 11 is opened, and the air extraction pump 12 is started through an external power supply to reduce the air pressure inside the storage barrel 4. The air extraction valve 11 is closed, and the water bath heater 2 is filled with hot water through the water exchange pipe 3. At the same time, the motor 10 is started through an external power supply. The motor 10 drives the stirring blade 8 to work through the gear set 9 and the rotating shaft 7 to improve the reaction efficiency of the device. The connecting pipe 13 is opened, and the vapor of the solution volatilized after heating enters the condensation barrel 15 through the connecting pipe 13. The vapor is cooled by the water cooling box 18 and the condensation pipe 20 connected to the inside of the condensation barrel 15 to achieve solid-liquid separation and crystallization.

[0034] When the device works for a long time, residual crystals may be attached to the inner wall of the condensation barrel 15 and the surface of the internal condensation tube 20. At this time, close the first valve 14 and the second valve 17 on one side, remove the installation cover 151, clean the inside of the device, and the condensation barrel 15 on the other side continues to work, thereby improving the cleanliness and adaptability of the device.

[0035] The above shows and describes the basic principle, main features and advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments, and the above embodiments and descriptions are only for explaining the principle of the utility model. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, and these changes and improvements fall within the scope of the utility model to be protected.

Claims

1. A refining device for the synthesis of phenylbutazone, comprising a bottom plate (1), characterized in that: A water bath heater (2) is fixedly arranged on the surface of the bottom plate (1), a water exchange pipe (3) is fixedly connected to the outer wall of the water bath heater (2), a storage barrel (4) is tightly fitted to the inner wall of the water bath heater (2), a cover plate (5) is fixedly installed on the top of the storage barrel (4), a feed pipe (6) is fixedly connected above the cover plate (5), a top cover (61) is snap-fitted on the top of the feed pipe (6), one end of a connecting pipe (13) is fixedly connected to one side of the storage barrel (4), the other end of the connecting pipe (13) is fixedly connected to a first valve (14), and one end of the first valve (14) is fixedly connected to the surface of a condensation barrel (15).

2. A refining device for the synthesis of phenylbutazone according to claim 1, characterized in that: The top of the condensation barrel (15) is snap-fitted with a mounting cover (151), the top of the mounting cover (151) is fixedly connected to a second valve (17), and the rear side of the second valve (17) is fixedly connected to a water cooling box (18).

3. A refining device for the synthesis of phenylbutazone according to claim 2, characterized in that: A water pump (19) is fixedly arranged inside the water cooling box (18), a condenser (20) is fixedly connected to the surface of the water pump (19), and one end of the condenser (20) is fixedly connected to the condenser (20) inside the condensation barrel (15) via a second valve (17).

4. A refining device for the synthesis of phenylbutazone according to claim 1, characterized in that: A rotating shaft (7) is provided inside the cover plate (5), the bottom end of the rotating shaft (7) is fixedly connected to a stirring blade (8), the top end of the rotating shaft (7) is fixedly connected to one side of a gear set (9), and the other side of the gear set (9) is fixedly connected to the output end of a motor (10).

5. A refining device for the synthesis of phenylbutazone according to claim 1, characterized in that: A drain valve (16) is fixedly connected to the outer wall of the condensation barrel (15) near the bottom, and the number of the condensation barrels (15) and the number of the first valves (14) and the second valves (17) are both two.

6. A refining device for the synthesis of phenylbutazone according to claim 1, characterized in that: One end of the material storage barrel (4) is fixedly connected to one end of an air extraction valve (11), and the other end of the air extraction valve (11) is fixedly connected to an air extraction pump (12).

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