High-efficiency HPV (human papillomavirus) typing rapid detection kit

Abstract

The utility model relates to the technical field of kits, in particular to an efficient HPV (human papillomavirus) typing rapid detection kit which comprises a kit body, and a kit cover is mounted on the outer wall of the kit body; the arc-shaped convex edge drives the sealing adhesive tape to be torn off, the sampling brush in the clamping groove is taken, after the sampling brush extracts a sample, the liquid storage bottle body is opened, the extracted sample is mixed with liquid in the liquid storage bottle body, and then the dropper is used for dropping the mixed liquid onto the pyrophosphoric acid test plate and the DNA test plate for determination. DNA bar code technology detection and pyrosequencing technology detection can be directly carried out, operation is easy and convenient, the step of taking packaging bags is omitted, and the whole detection process is faster; the medical waste in the inner cavity of the sealing groove is sealed by inserting the sealing rubber plug into the end opening of the sealing groove, the box body is not easily punctured by the sharp part of the sampling brush, and then the box body is placed in the inner cavity of the recycling bag, so that the medical waste is further sealed, and the pollution to the environment is prevented.

Description

Technical Field

[0001] The utility model relates to the technical field of reagent kits, in particular to a high-efficiency HPV typing rapid detection kit. Background Art

[0002] HPV, or human papillomavirus, is a species-specific epitheliotropic virus and a spherical DNA virus without an envelope. Persistent HPV infection is the main cause of CIN and its progression to invasive cancer. It is a necessary condition for the development of cervical cancer and precancerous lesions. HPV can be divided into two categories: low-risk and high-risk types according to the pathogenicity or carcinogenic risk of HPV subtypes. Common high-risk HPV types include HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, and 68. High-risk HPV can cause cervical cancer and high-grade cervical intraepithelial neoplasia. Therefore, high-risk HPV testing plays an increasingly important role in cervical cancer screening.

[0003] The HPV typing rapid detection kits currently on the market are relatively complex in design and contain multiple components, such as independent sampling sticks, detection reagents and sample storage bottles. These components need to be packaged separately and the packaging bags must be opened and taken out separately before use. This makes the operation steps cumbersome and increases the overall detection time, thereby affecting the detection efficiency and failing to achieve rapid detection. In addition, the amount of waste after use is large and needs to be properly handled to prevent environmental pollution. For this reason, special storage bags are usually required for waste storage. However, since the tip of the sampling stick is sharp, it can easily penetrate the storage bag, which may cause potential environmental pollution problems, thereby reducing the practicality of the product.

[0004] Therefore, an efficient HPV typing rapid detection kit is needed to improve the above problems. Utility Model Content

[0005] In order to solve the problem that when a rapid detection kit is used to detect HPV, all components need to be packaged separately and the packaging bags need to be opened and taken out separately before use, which makes the operation steps cumbersome and increases the overall detection time, thereby affecting the detection efficiency and failing to achieve rapid detection, the utility model provides an efficient HPV typing rapid detection kit to solve the above problem.

[0006] To achieve the above objectives, the present invention provides the following technical solutions:

[0007] A high-efficiency HPV typing rapid detection kit comprises a box body, a box cover is installed on the outer wall of the box body, a flexible board is installed on the side wall of the box cover, and a sealing rubber plug is provided on the inner wall of the flexible board, a sealing groove is provided on the side wall of the box body, and a recovery bag is provided on the inner wall of the sealing groove, a shell is provided on the inner wall of the box body, a reagent fixing groove is provided on the outer wall of the shell, two groups of the reagent fixing grooves are provided and respectively place a pyrophosphate test plate and a DNA test plate, a liquid bottle placement groove is provided on the outer wall of the shell, a liquid bottle fixing hole is provided on the outer wall of the shell, a storage groove is provided on the outer wall of the shell, a card slot is provided on the outer wall of the shell, and the card slot is shaped like a cross structure, and sealing tapes are adhered to the ports of the reagent fixing groove, the liquid bottle placement groove and the card slot, and one end of the sealing tape is provided with an arc-shaped convex edge.

[0008] As a preferred solution of the present invention, a liquid storage bottle body is provided on the inner wall of the liquid storage bottle placement groove, and the inner cavity of the liquid storage bottle body is provided with sample preservation liquid, a sampling brush is provided on the inner wall of the card slot, and a crease line is provided at the connection between the box cover and the box body.

[0009] As a preferred solution of the present invention, the sealing rubber plug is located on one side of the box body, and the connection between the sealing rubber plug and the sealing groove is a plug-in connection.

[0010] As a preferred solution of the present invention, the recycling bag is located directly below the shell, and the cross-section of the shell is a Z-shaped structure, and the material of the flexible board is paper material.

[0011] As a preferred solution of the present invention, the reagent fixing grooves are provided in two groups and are respectively located on the outer wall of the shell, and the reagent fixing grooves are located directly below the box cover, and the liquid storage bottle placement groove is located on one side of the liquid storage bottle fixing hole.

[0012] As a preferred solution of the present invention, the inner cavity of the storage slot is provided with instructions and a dropper, the card slot is located on one side of the liquid storage bottle placement slot, and a sealing gasket is provided just below the box cover and at the port of the box body.

[0013] As a preferred solution of the present invention, the sealing tapes are provided in multiple groups and are respectively located at the ports of the reagent fixing slot, the liquid storage bottle placement slot and the card slot.

[0014] As a preferred solution of the present invention, the sealing tape and the arc-shaped convex edge are both made of medical plastic materials, and the recycling bag is made of low-density polyethylene material.

[0015] Compared with the prior art, the present invention sets a flexible plate in the high-efficiency HPV typing rapid detection kit to drive the box cover to open, and the flexible plate drives the sealing rubber plug to pull out the sealing groove. When the box body is fully unfolded, the recovery bag can be taken out. It is only necessary to pull the arc-shaped convex edge to drive the sealing tape to tear off, and then the sampling brush in the card slot can be taken out. After the sampling brush extracts the sample, the liquid storage bottle is opened in the same way as above, and the extracted sample is mixed with the liquid in the liquid storage bottle. Then, a dropper is used to drop the mixed liquid onto the pyrophosphate test plate and the DNA test plate for measurement, and DNA barcode technology detection and pyrophosphate detection can be directly performed. The sequencing technology is used for detection and is easy to operate. Compared with traditional test kits, the device saves the step of taking the packaging bag. You only need to open the box body and tear off the sealing tape to take it out for testing, making the entire detection process faster, thus solving the problem that the HPV typing rapid detection kits on the current market are relatively complex in design. They contain multiple components, such as independent sampling sticks, detection reagents and sample storage bottles. These parts need to be packaged separately and the packaging bags must be opened and taken out separately before use. This makes the operation steps cumbersome and increases the overall detection time, thereby affecting the detection efficiency and failing to achieve rapid detection.

[0016] The utility model places sealing tape in the inner cavity of the sealing groove for storage in the high-efficiency HPV typing rapid detection kit, and then after the test results come out, the liquid storage bottle and the sampling brush can be placed in the inner cavity of the sealing groove. It is only necessary to insert the sealing rubber plug into the port of the sealing groove to seal the medical waste in the inner cavity of the sealing groove. Since the box body is not easily pierced by the sharp part of the sampling brush, the box body is then placed in the inner cavity of the recovery bag to further seal the medical waste to prevent pollution to the environment, thereby solving the problem of a large amount of waste after use, which needs to be properly handled to prevent environmental pollution. For this reason, it is usually necessary to use a special storage bag for waste storage. However, since the tip of the sampling stick is sharp, it is easy to penetrate the storage bag, which may cause potential environmental pollution problems, thereby reducing the practicality of the product. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0018] Figure 2 This is a schematic diagram of the expanded structure of the box body of the present utility model;

[0019] Figure 3 This is a schematic diagram of the top view of the structure of the utility model;

[0020] Figure 4 This is a schematic diagram of the box body structure of the utility model;

[0021] Figure 5 This is a schematic diagram of the sealing rubber plug structure of the present utility model.

[0022] In the figure: 1. Box body; 2. Box cover; 3. Flexible board; 4. Sealing rubber plug; 5. Sealing groove; 6. Recovery bag; 7. Shell; 8. Reagent fixing groove; 9. Pyrophosphate test plate; 10. DNA test plate; 11. Liquid storage bottle placement groove; 12. Liquid storage bottle fixing hole; 13. Storage slot; 14. Card slot; 15. Sealing tape; 16. Arc convex edge; 17. Liquid storage bottle body; 18. Sampling brush. DETAILED DESCRIPTION

[0023] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0024] Example: See Figure 1-5 The shown high-efficiency HPV typing rapid detection kit includes a box body 1, a box cover 2 is installed on the outer wall of the box body 1, a flexible board 3 is installed on the side wall of the box cover 2, and a sealing rubber plug 4 is provided on the inner wall of the flexible board 3, a sealing groove 5 is provided on the side wall of the box body 1, and a recovery bag 6 is provided on the inner wall of the sealing groove 5, a shell 7 is provided on the inner wall of the box body 1, a reagent fixing groove 8 is provided on the outer wall of the shell 7, two groups of reagent fixing grooves 8 are provided and respectively place a pyrophosphate test plate 9 and a DNA test plate 10, a liquid bottle placement groove 11 is provided on the outer wall of the shell 7, a liquid bottle fixing hole 12 is provided on the outer wall of the shell 7, a storage groove 13 is provided on the outer wall of the shell 7, and a card slot 14 is provided on the outer wall of the shell 7, and the card slot 14 is shaped like a cross structure, and sealing tape 15 is adhered to the ends of the reagent fixing groove 8, the liquid bottle placement groove 11 and the card slot 14, and one end of the sealing tape 15 is provided with an arc-shaped convex edge 16.

[0025] In this embodiment, specific reference Figure 1 、 Figure 2 、 Figure 3 、 Figure 4 and Figure 5, a liquid storage bottle body 17 is provided on the inner wall of the liquid storage bottle placement groove 11, and the inner cavity of the liquid storage bottle body 17 is provided with a sample preservation liquid, a sampling brush 18 is provided on the inner wall of the card slot 14, a crease line is provided at the connection between the box cover 2 and the box body 1, a sealing rubber plug 4 is located on one side of the box body 1, and the connection method of the sealing rubber plug 4 and the sealing groove 5 is a plug-in connection, a recovery bag 6 is located directly below the shell 7, and the cross-section of the shell 7 is a Z-shaped structure, the material of the flexible board 3 is paper material, and the reagent fixing groove 8 is provided with two groups and is respectively located on the outer wall of the shell 7 , and the reagent fixing groove 8 is located directly below the box cover 2, the liquid storage bottle placement groove 11 is located on one side of the liquid storage bottle fixing hole 12, the inner cavity of the storage groove 13 is provided with an instruction manual and a dropper, the card slot 14 is located on one side of the liquid storage bottle placement groove 11, and a sealing gasket is provided directly below the box cover 2 and at the port of the box body 1. There are multiple groups of sealing tapes 15 and they are respectively located at the ports of the reagent fixing groove 8, the liquid storage bottle placement groove 11 and the card slot 14. The materials of the sealing tapes 15 and the arc-shaped convex edge 16 are both medical plastic materials, and the material of the recovery bag 6 is low-density polyethylene material.

[0026] Among them, the box body 1 and the box cover 2 are both made of plastic film paper material, which makes the device more waterproof, and the reagent fixing groove 8 has a fixing effect on the pyrophosphate test plate 9 and the DNA test plate 10, and the liquid storage bottle fixing hole 12 is located between the pyrophosphate test plate 9 and the DNA test plate 10 to facilitate detection.

[0027] When the high-efficiency HPV typing rapid detection kit of this scheme is in operation, a box cover 2 is installed on the outer wall of the box body 1, a flexible plate 3 is installed on the side wall of the box cover 2, and a sealing rubber plug 4 is provided on the inner wall of the flexible plate 3. It only needs to apply tension to the flexible plate 3 to make the flexible plate 3 drive the box cover 2 to open. At the same time, a sealing groove 5 is opened on the side wall of the box body 1, and a recycling bag 6 is provided on the inner wall of the sealing groove 5. The sealing rubber plug 4 is located on one side of the box body 1, and the connection method of the sealing rubber plug 4 and the sealing groove 5 is plug-in connection. The recycling bag 6 is convenient to use. The bag 6 is located just below the shell 7, and the flexible plate 3 drives the sealing rubber plug 4 to pull out the sealing groove 5. The box body 1 is fully unfolded, and the recovery bag 6 can be taken out. At the same time, the reagent fixing groove 8, the liquid bottle placement groove 11 and the end of the card slot 14 are respectively adhered with sealing tape 15, and one end of the sealing tape 15 is provided with an arc-shaped convex edge 16. When it is needed to be used, it is only necessary to pull the arc-shaped convex edge 16 to make the arc-shaped convex edge 16 drive the sealing tape 15 to tear, and then the sampling brush 18 in the card slot 14 can be taken out. After the sample is extracted by the sample brush 18, the liquid storage bottle 17 is taken out in the same way as above, and then the liquid storage bottle 17 is opened. After the extracted sample is mixed with the liquid in the liquid storage bottle 17, a dropper is used to drop the mixed liquid onto the pyrophosphate test plate 9 and the DNA test plate 10 for measurement. DNA barcode technology detection and pyrophosphate sequencing technology detection can be directly performed. The operation is simple and the operation steps are fewer than those of traditional test kits. The previous one required opening the box body 1, first taking out the component packaging bags in turn, and then tearing them open in turn for use. The device saves the step of taking out the packaging bags. It only needs to open the box body 1 and tear off the sealing tape 15 to take it out for testing, making the entire testing process faster, thereby solving the problem that the HPV typing rapid detection kit currently on the market is relatively complex in design, which contains multiple components, such as independent sampling sticks, detection reagents and sample storage bottles. These components need to be packaged separately and the packaging bags must be opened and taken out before use. This results in cumbersome operation steps, increases the overall detection time, thereby affecting the detection efficiency and failing to achieve rapid detection.

[0028] By opening a sealing groove 5 on the side wall of the box body 1 and providing a recovery bag 6 on the inner wall of the sealing groove 5, the device first generates less waste. Compared with packaging bags, the device only generates sealing tape 15. The sealing tape 15 is placed in the inner cavity of the sealing groove 5 for storage. After the test results are out, the liquid storage bottle 17 and the sampling brush 18 can be placed in the inner cavity of the sealing groove 5. The waste pollution source is placed in the inner cavity of the sealing groove 5. It is only necessary to insert the sealing rubber plug 4 into the port of the sealing groove 5 to seal the medical waste in the inner cavity of the sealing groove 5. Since the box body 1 is not easily pierced by the sharp part of the sampling brush 18, the box body 1 is then placed in the inner cavity of the recovery bag 6 to further seal the medical waste to prevent pollution to the environment, thereby solving the problem of a large amount of waste after use, which needs to be properly handled to prevent environmental pollution. To this end, a special storage bag is usually required to store the waste. However, since the tip of the sampling rod is sharp, it is easy to penetrate the storage bag, which may cause potential environmental pollution problems, thereby reducing the practicality of the product.

[0029] Although the embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations may be made to these embodiments without departing from the principles and spirit of the present invention, and the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An efficient HPV typing rapid detection kit, comprising a box body (1), characterized in that: The outer wall of the box body (1) is provided with a box cover (2), the side wall of the box cover (2) is provided with a flexible plate (3), and the inner wall of the flexible plate (3) is provided with a sealing rubber plug (4), the side wall of the box body (1) is provided with a sealing groove (5), and the inner wall of the sealing groove (5) is provided with a recovery bag (6), the inner wall of the box body (1) is provided with a shell (7), and the outer wall of the shell (7) is provided with a reagent fixing groove (8), and the reagent fixing groove (8) is provided with two groups, and a pyrophosphate test plate (9) and a DNA test plate (9) are placed respectively. The plate (10) is provided with a liquid storage bottle placement groove (11) on the outer wall of the shell (7), a liquid storage bottle fixing hole (12) is provided on the outer wall of the shell (7), a storage groove (13) is provided on the outer wall of the shell (7), a card slot (14) is provided on the outer wall of the shell (7), and the card slot (14) is in the shape of a cross structure, and sealing tapes (15) are respectively adhered to the ends of the reagent fixing groove (8), the liquid storage bottle placement groove (11) and the card slot (14), and one end of the sealing tape (15) is provided with an arc-shaped convex edge (16).

2. An efficient HPV typing rapid detection kit according to claim 1, characterized in that: A liquid storage bottle body (17) is arranged on the inner wall of the liquid storage bottle placement groove (11), and a sample preservation liquid is arranged in the inner cavity of the liquid storage bottle body (17), a sampling brush (18) is arranged on the inner wall of the card slot (14), and a crease line is arranged at the connection between the box cover (2) and the box body (1).

3. An efficient HPV typing rapid detection kit according to claim 1, characterized in that: The sealing rubber plug (4) is located on one side of the box body (1), and the sealing rubber plug (4) and the sealing groove (5) are connected in a plug-in manner.

4. The high-efficiency HPV typing rapid detection kit according to claim 1, characterized in that: The recycling bag (6) is located directly below the shell (7), and the cross-section of the shell (7) is a Z-shaped structure. The material of the flexible board (3) is paper material.

5. The high-efficiency HPV typing rapid detection kit according to claim 1, characterized in that: The reagent fixing grooves (8) are provided in two groups and are respectively located on the outer wall of the housing (7), and the reagent fixing grooves (8) are located directly below the box cover (2), and the liquid storage bottle placement groove (11) is located on one side of the liquid storage bottle fixing hole (12).

6. The high-efficiency HPV typing rapid detection kit according to claim 1, characterized in that: The inner cavity of the storage slot (13) is provided with an instruction manual and a dropper, the card slot (14) is located on one side of the liquid storage bottle placement slot (11), and a sealing gasket is provided directly below the box cover (2) and at the port of the box body (1).

7. The high-efficiency HPV typing rapid detection kit according to claim 1, characterized in that: The sealing tapes (15) are provided in multiple groups and are respectively located at the ports of the reagent fixing slot (8), the liquid storage bottle placement slot (11) and the card slot (14).

8. The high-efficiency HPV typing rapid detection kit according to claim 1, characterized in that: The sealing tape (15) and the arc-shaped convex edge (16) are both made of medical plastic materials, and the recycling bag (6) is made of low-density polyethylene material.

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