Reagent storage device and sequencing system

By setting up a pressurized module and a drain module in the reagent storage device, the problem of condensate water contamination reagents caused by the entry of external air is solved, and the effect of improving the quality of the reagent and sequencing accuracy is achieved.

CN222555589UActive Publication Date: 2025-03-04MGI TECH CO LTD
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Patent Information

Application Number
CN202421333258.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-12
Publication Date
2025-03-04
Estimated Expiration
2034-06-12

AI Technical Summary

Technical Problem

During gene sequencing, the negative pressure in the reagent storage device causes external air to enter, causing condensate water to form and contaminate the reagent, affecting the sequencing quality.

Method used

A reagent storage device is designed, including a pressurization module and a liquid discharge module. The pressurized module replenishes gas into the interior of the tank through an air pump, increases the air pressure and prevents external air from entering; the liquid discharge module discharges condensed water through the liquid discharge pipe.

Benefits of technology

By increasing the air pressure inside the cabin, external air is prevented from entering, thereby reducing the formation of condensate, avoiding reagent contamination, and ensuring the quality of reagents and the accuracy of sequencing results.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a reagent storage device, comprising: a storage cabin, which comprises a cabin door, a refrigeration part and a cabin body, the refrigeration part is arranged in the cabin body, and the cabin door and the cabin body jointly form an accommodating cavity for accommodating a reagent; the pressurizing module comprises an air channel pipe and an air pump, the air pump is arranged on the outer side of the cabin body, the air channel pipe communicates with the air pump and penetrates through the cabin body to communicate the inner side and the outer side of the cabin body, and the end, located in the cabin body, of the air channel pipe faces the refrigerating part; the liquid discharging module comprises a liquid discharging pipe, the liquid discharging pipe is arranged on the outer side of the cabin body and communicates with the inner side of the cabin body, and the liquid discharging pipe is used for discharging condensed water in the cabin body. The reagent storage device provided by the utility model is beneficial to preventing condensed water in the cabin body from polluting the reagent placed in the cabin body. The utility model further provides a sequencing system applying the reagent storage device.
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Description

Technical Field

[0001] The present application relates to a reagent storage device and a sequencing system using the reagent storage device. Background Art

[0002] Common gene sequencing systems usually include a reagent storage device, which is used to store reagents for reacting with samples so that the reagents are stored under low temperature conditions that can maintain activity. The reagent storage device is usually provided with a pinhole so that the reagent needle can extract the reagent placed in the reagent storage device through the pinhole. However, the operation of extracting the reagent will cause negative pressure in the reagent storage device. Some reagent storage devices will be provided with a condensation water extraction device, which will also cause negative pressure in the reagent storage device, so that the external air with a high temperature and a certain humidity enters the reagent storage device. In addition, during the sequencing process, the door of the reagent storage device is often opened, which further aggravates the entry of external air into the reagent storage device. The air with a high temperature and humidity will produce a condensation effect after entering the low temperature environment and condense into condensed water. The condensed water formed on the inner upper wall of the reagent storage device or the condensed water formed at the pinhole may fall into the reagent, causing the reagent to be contaminated, thereby affecting the quality of sequencing. Utility Model Content

[0003] On the one hand, the present application provides a reagent storage device. The reagent storage device comprises:

[0004] A storage cabin, comprising a cabin door, a refrigeration unit and a cabin body, wherein the refrigeration unit is arranged in the cabin body, and the cabin door and the cabin body together constitute a containing cavity for containing reagents; and

[0005] A pressurizing module, comprising an air pipe and an air pump, wherein the air pump is arranged outside the cabin, the air pipe is communicated with the air pump and penetrates the cabin to connect the inside and outside of the cabin, and one end of the air pipe located in the cabin is arranged toward the refrigeration unit;

[0006] The drainage module comprises a drainage pipe, wherein the drainage pipe is arranged outside the cabin and communicated with the inside of the cabin, and the drainage pipe is used to discharge the condensed water in the cabin.

[0007] The reagent storage device provided in the embodiment of the present application can replenish gas to the interior of the cabin by setting a pressurizing module, thereby increasing the air pressure inside the cabin, making the air pressure inside the cabin higher than the air pressure outside the cabin, thereby making it difficult for air with higher external temperature to enter the cabin. The gas entering the cabin through the pressurizing module can be quickly cooled by the refrigeration unit, thereby avoiding the formation of condensed water on the inner upper wall of the cabin, thereby avoiding contamination of the reagent, which is beneficial to ensuring the quality of the reagent.

[0008] In one embodiment, the pressurizing module further includes an air filter unit, the air filter unit is connected to an end of the air pump away from the cabin, the air filter unit includes an impurity filter module, and the impurity filter module is used to filter impurities in the air.

[0009] In one embodiment, the air filter unit further includes a dehumidification module, and the dehumidification module is used to filter moisture in the air.

[0010] In one embodiment, the pressurizing module further includes a pressure sensing unit, which is disposed in the cabin and is used to sense the air pressure in the cabin.

[0011] In one embodiment, the pressurizing module further includes a control unit, which is electrically connected to the pressure sensing unit and the air pump, and is used to control the switch of the air pump according to the air pressure sensed by the pressure sensing unit.

[0012] In one embodiment, the drainage module further includes a liquid pump, which is disposed on the outside of the cabin and communicated with the drainage pipe for extracting moisture from the cabin.

[0013] In one embodiment, the drainage module further includes a collection box, which is disposed on the outside of the cabin and communicated with the drainage pipe for collecting moisture discharged from the cabin by the drainage pipe.

[0014] In one embodiment, a drainage groove and a drainage port are provided on the bottom wall of the cabin body, the drainage groove is communicated with the drainage port, and the drainage port is communicated with the drainage pipe.

[0015] In one embodiment, a liquid collection needle hole is further provided on the top wall of the cabin, and the liquid collection needle hole is used to connect the inner and outer sides of the cabin.

[0016] Another aspect of the present application provides a sequencing system, comprising:

[0017] The reagent storage device described in any of the above embodiments, wherein the reagent storage device is used to store reagents;

[0018] a liquid extraction device, comprising a liquid extraction needle, the liquid extraction needle being used to extract the reagent from the reagent storage device; and

[0019] The sequencing device is used for sequencing the sample. The sequencing device is also used for receiving the reagent extracted by the liquid collection needle and for making the reagent react with the sample.

[0020] The sequencing system provided in the embodiment of the present application, by adopting the reagent storage device in the above embodiment, is conducive to avoiding the generation of condensed water on the inner upper wall of the reagent storage device, thereby avoiding reagent contamination caused by condensed water falling into the reagent, which is conducive to ensuring the quality of sequencing. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 Schematic diagram of the structure of the reagent storage device in the embodiment of the present application.

[0022] Figure 2 for Figure 1 Schematic diagram of the cross-sectional structure of the storage compartment along line II-II.

[0023] Figure 3 Schematic diagram of the structure of the sequencing system in the embodiment of the present application.

[0024] Main component symbols

[0025] Reagent storage device 100

[0026] Storage compartment 10

[0027] Hatch 11

[0028] Accommodating chamber 12

[0029] Cabin 13

[0030] Side wall 131

[0031] Drain port 132

[0032] Bottom wall 133

[0033] Drainage tank 134

[0034] Upper wall 135

[0035] Liquid collection pinhole 136

[0036] Refrigeration unit 15

[0037] Pressurized module 30

[0038] Gas line 31

[0039] Air pump 33

[0040] Air filter 35

[0041] Impurity Filter Module 351

[0042] Dehumidification module 353

[0043] Pressure sensing unit 37

[0044] Control unit 39

[0045] Drainage module 50

[0046] Drain pipe 51

[0047] Liquid pump 53

[0048] Collection Box 55

[0049] Sequencing System 200

[0050] Liquid taking device 210

[0051] Liquid collection needle 211

[0052] Sequencing device 230

[0053] The following specific implementation methods will further illustrate the present application in conjunction with the above-mentioned drawings. DETAILED DESCRIPTION

[0054] The technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all of the embodiments.

[0055] Unless otherwise defined, all technical and scientific terms used in this application have the same meaning as those commonly understood by those skilled in the art to which this application belongs. The terms used in the specification of this application are only for the purpose of describing specific embodiments and are not intended to limit this application.

[0056] In order to further explain the technical means and effects adopted by the present application to achieve the intended purpose, the present application is described in detail below in conjunction with the accompanying drawings and preferred implementation methods.

[0057] See also Figure 1 The reagent storage device 100 provided in the embodiment of the present application includes a storage compartment 10, a pressurizing module 30, and a drainage module 50. The storage compartment 10 is used to store reagents, and the pressurizing module 30 is used to fill gas into the storage compartment 10 to increase the air pressure in the storage compartment 10. The drainage module 50 is used to discharge moisture in the storage compartment 10.

[0058] The storage compartment 10 includes a compartment door 11, a compartment body 13, and a refrigeration unit 15. The compartment door 11 and the compartment body 13 together form a receiving chamber 12 for receiving reagents. The refrigeration unit 15 is disposed in the compartment body 13 and is used to adjust the temperature in the receiving chamber 12.

[0059] Specifically, in this embodiment, the hatch 11 is rotatably connected to the cabin body 13, and the hatch 11 can be opened and closed by rotating relative to the cabin body 13. In other embodiments, the hatch 11 and the cabin body 13 can also be combined in other ways, for example, the hatch 11 can be set as a push-pull structure, pushed toward the cabin body 13 through a guide rail to form a closed accommodating cavity 12 with the cabin body 13, or set as a snap-fit ​​structure, snapped on the cabin body 13 by snaps, etc., and the present application does not limit the specific combination method of the hatch 11 and the cabin body 13.

[0060] Please refer to Figure 1 and Figure 2 The cabin 13 includes a plurality of side walls 131, a bottom wall 133 and an upper wall 135. The bottom wall 133 is arranged opposite to the upper wall 135. Each side wall 131 is connected between the bottom wall 133 and the upper wall 135. In the present embodiment, the pressurizing module 30 and the drainage module 50 respectively penetrate a side wall 131 to connect the inner and outer sides of the cabin 13. Specifically, the pressurizing module 30 penetrates the side wall 131 to fill the cabin 13 with gas so as to increase the air pressure in the accommodating cavity 12. The drainage module 50 penetrates the side wall 131 to discharge the condensed water condensed in the cabin 13. In other embodiments, the pressurizing module 30 may also penetrate the bottom wall 133 or the upper wall 135, and the drainage module 50 may also penetrate the bottom wall 133, and the present application does not limit this.

[0061] In this embodiment, a drainage groove 134 and a drainage port 132 are provided on the bottom wall 133. The drainage port 132 is connected to the drainage groove 134, and penetrates the side wall 131 from the connection between the bottom wall 133 and the side wall 131, so as to be connected to the drainage module 50. Specifically, the drainage groove 134 is a mesh groove provided on the bottom wall 133 and connected to each other, and the drainage groove 134 is used to collect condensed water condensed in the cabin 13. The drainage port 132 is connected to one end of the drainage groove 134, and is used to guide the condensed water to the drainage module 50. The bottom wall of the drainage groove 134 can be designed to have a certain continuous slope, and the drainage port 132 is located at the lowest end of the slope of the drainage groove 134, so that the condensed water flowing into the drainage groove 134 can flow toward the drainage port 132 under the action of gravity. The drain port 132 extends from the bottom wall 133 and penetrates the side wall 131, so that the drain module 50 can be connected to the interior of the cabin 13 through the drain port 132, thereby discharging the condensed water flowing to the drain port 132. In other embodiments, the drain module 50 can also be completely arranged on the outside of the cabin 13 and connected to the drain port 132. Or the bottom wall 133 of the cabin 13 can also be only provided with the drain port 132, and the bottom wall 133 as a whole is an inclined surface inclined toward the position of the drain port 132. This application does not limit this, as long as the drain module 50 can discharge the condensed water in the cabin 13, it is within the scope of this application.

[0062] A liquid collection needle hole 136 is also provided on the upper wall 135 of the cabin 13, and the liquid collection needle hole 136 is used to connect the inner and outer sides of the cabin 13. Specifically, in the present embodiment, the reagent is contained in a container (not shown) with an opening on the top, and is placed in the cabin 13, and the opening of the container is provided corresponding to the liquid collection needle hole 136. The liquid collection needle located outside the storage cabin 10 can penetrate into the cabin 13 through the liquid collection needle hole 136, so as to extract the reagent from the container. Only one liquid collection needle hole 136 can be provided, or multiple liquid collection needle holes 136 can be provided, and can be specifically provided according to the number of containers for containing the reagents corresponding to the actual placement of the reagents. The position of the liquid collection needle hole 136 can also be provided in accordance with the arrangement position of the containers placed in the storage cabin 10.

[0063] Please continue reading Figure 1 The refrigeration unit 15 is disposed in the cabin 13 to adjust the temperature in the cabin 13. Specifically, the refrigeration unit 15 may be a refrigeration plate, and a refrigeration medium is disposed inside the refrigeration unit 15. The refrigeration unit 15 is connected to an external compressor so that the refrigeration medium is converted between gas and liquid, thereby absorbing the heat in the cabin 13 and further reducing the temperature of the cabin 13. In other embodiments, the refrigeration unit 15 may also be configured as a refrigeration device of other structures, such as a Peltier, which is not limited in the present application.

[0064] In the present embodiment, the refrigeration unit 15 is used to adjust the temperature in the cabin 13 to 2-8°C. Specifically, the reagent storage device 100 is used to store reagents for reacting with samples during gene sequencing. In an environment of 2-8°C, the reagents can remain active so that they can fully react with the samples. In other embodiments, the reagent storage device 100 can also be used to store other reagents. Depending on the different temperatures at which different reagents maintain their activity, the refrigeration unit 15 can also adjust the temperature in the cabin 13 to different temperature ranges, and the present application does not impose any restrictions on this.

[0065] The pressurizing module 30 includes an air pipe 31, an air pump 33, and an air filter 35. The air pipe 31 is connected to the air pump 33 and penetrates the side wall 131 of the cabin 13 to connect the inside and outside of the cabin 13. The air pump 33 is arranged on the outside of the cabin 13 and is used to pump gas into the cabin 13 through the air pipe 31. The air filter 35 is connected to one end of the air pump 33 away from the cabin 13.

[0066] One end of the gas circuit tube 31 located in the cabin 13 is arranged toward the refrigeration unit 15. Specifically, when the air pump 33 pumps gas into the cabin 13 through the gas circuit tube 31, the gas will first encounter the refrigeration unit 15 because the end of the gas circuit tube 31 is arranged toward the refrigeration unit 15. On the one hand, when the gas with a higher external temperature enters the cabin 13, it will first contact with the refrigeration unit 15, so the temperature can be quickly reduced, so as not to affect the overall temperature in the cabin 13. On the other hand, since the gas may contain water vapor, since the gas first contacts with the refrigeration unit 15, the water vapor will first condense on the refrigeration unit 15 to form condensed water, and will not condense at other locations in the cabin 13, especially the container for containing reagents, the upper wall 135 of the cabin 13, and the position near the liquid collection needle hole 136, thereby avoiding condensed water from contaminating the reagent.

[0067] The air pump 33 may be a brushless air pump, or other air pump structures, which is not limited in the present application.

[0068] The air pump 33 is used to pump gas into the cabin 13, so that the air pressure in the cabin 13 is higher than the external atmospheric pressure. Specifically, by setting the air pump 33 to pump gas into the cabin 13, a slightly positive pressure state can be achieved, so that the external air is not easy to enter the cabin 13. First, when the liquid extraction needle extracts the liquid in the cabin 13, the air pump 33 will supplement the negative pressure generated by the extraction of the reagent, thereby preventing the external air from entering the cabin 13 through the liquid extraction needle hole 136. Second, when the liquid discharge module 50 discharges the condensed water in the cabin 13, the air pump 33 will also supplement the negative pressure generated by the discharge of the condensed water, thereby preventing the external air from entering the cabin 13. Third, when the cabin door 11 is opened, since the air pressure inside the cabin 13 is higher than the external air pressure, the gas in the cabin 13 will flow toward the outside of the cabin 13, thereby blocking the external gas from flowing toward the cabin 13.

[0069] By blocking external air from entering the cabin 13, it is possible to effectively prevent water vapor in the external air from condensing into condensed water after encountering the low-temperature structure in the cabin 13, especially near the container for reagents, the upper wall 135 of the cabin 13, and the liquid extraction needle hole 136, thereby preventing condensed water from flowing into the reagent and contaminating the reagent.

[0070] In this embodiment, the air filter 35 is arranged at one end of the air pump 33 away from the cabin 13, so as to filter the air flowing to the air pump 33. Specifically, the air filter 35 includes an impurity filter module 351 and a dehumidification module 353. The impurity filter module 351 is used to filter impurities in the air, such as bacteria, dust, dust and other tiny particles, or chemical substances that easily react with the reagents in the cabin 13. The components filtered by the impurity filter module 351 can be set according to actual needs, and this application does not limit this. The dehumidification module 353 is arranged between the impurity filter module 351 and the air pump 33, and is used to filter the moisture in the air, thereby reducing the amount of condensed water condensed in the cabin 13. In other embodiments, according to actual use requirements, the reagent storage device 100 may not include the air filter 35, or only include one of the impurity filter module 351 or the dehumidification module 353, or integrate the impurity filter module 351 and the dehumidification module 353 into one, and this application does not limit this.

[0071] In this embodiment, the pressurizing module 30 further includes a pressure sensing unit 37 and a control unit 39. The pressure sensing unit 37 is disposed in the cabin 13 and is used to sense the air pressure in the cabin 13. The control unit 39 is electrically connected to the pressure sensing unit 37 and the air pump 33 and is used to control the switch of the air pump 33 according to the air pressure sensed by the pressure sensing unit 37.

[0072] Specifically, the pressure sensing unit 37 senses the air pressure in the cabin 13 to ensure that the air pressure in the cabin 13 is greater than the external air pressure. The control unit 39 can adjust the switch of the air pump 33 according to the air pressure value measured in the cabin 13. When the air pressure in the cabin 13 is lower than the external air pressure, the control unit 39 controls the air pump 33 to turn on, thereby pumping air into the cabin 13 to increase the air pressure inside the cabin 13. When the air pressure in the cabin 13 is higher than the external air pressure, the control unit 39 can turn off the air pump 33, thereby achieving an energy-saving effect. The control unit 39 can also be used to prevent the air pressure in the cabin 13 from being too high, so as to avoid damage to the structure of the cabin 13 due to high air pressure.

[0073] In other embodiments, the pressurizing module 30 may not include the pressure sensing unit 37 and the control unit 39, and the reagent storage device 100 may control the switch of the air pump 33 in other ways to achieve a micro-positive pressure. For example, the air pump 33 is turned on when the liquid extraction needle extracts the reagent, the air pump 33 is turned on when the liquid discharge module 50 discharges condensed water, and the air pump 33 is turned on after the door 11 is opened or closed, etc. The pressurizing module 30 may also only include the pressure sensing unit 37, and the user manually controls the switch of the air pump 33 according to the air pressure measured by the pressure sensing unit 37, and the present application does not limit this.

[0074] In this embodiment, the liquid discharge module 50 includes a liquid discharge pipe 51, a liquid pump 53, and a collection box 55. The liquid discharge pipe 51 is at least partially disposed outside the cabin 13 and communicated with the inside of the cabin 13. The liquid discharge pipe 51 is used to discharge condensed water in the cabin 13. The liquid pump 53 is disposed outside the cabin 13 and communicated with the liquid discharge pipe 51 to extract water from the cabin 13. The collection box 55 is disposed outside the cabin 13 and communicated with the liquid discharge pipe 51 to collect water discharged from the cabin 13.

[0075] Specifically, the drain pipe 51 sequentially connects the cabin 13, the liquid pump 53, and the collection box 55. The drain pipe 51 passes through the drain port 132 to communicate with the cabin 13, and is thereby connected with the drain groove 134, so that the condensed water condensed and flowing into the drain groove 134 can flow toward the drain pipe 51, and flow to the outside of the cabin 13 through the drain pipe 51. In other embodiments, the drain pipe 51 can also be arranged on the outside of the cabin 13 and communicate with the drain port 132, and the condensed water in the cabin 13 first passes through the drain port 132, and then flows into the drain pipe 51. The present application does not limit the specific arrangement of the drain pipe 51, as long as it can be connected with the inside of the cabin 13 to discharge the condensed water in the cabin 13, it is within the scope of the present application.

[0076] The liquid pump 53 is a diaphragm liquid pump, and the liquid pump 53 directly extracts the condensed water in the cabin 13 through the liquid discharge pipe 51, thereby accelerating the discharge speed of the condensed water. In other embodiments, the liquid discharge module 50 may not be provided with the liquid pump 53, and the condensed water is naturally discharged through the liquid discharge pipe 51.

[0077] The collecting box 55 is arranged on the side of the liquid pump 53 away from the storage compartment 10, and is used to collect the condensed water pumped out by the liquid pump 53. In other embodiments, the drainage module 50 may not include the collecting box 55, and the drainage pipe 51 may be directly connected to the outdoor or indoor drainage system. This application does not impose any restrictions on this.

[0078] The reagent storage device 100 provided in the embodiment of the present application can pump air into the cabin 13 of the storage cabin 10 by setting a pressurizing module 30, thereby increasing the air pressure in the cabin 13, and then forming a slightly positive pressure state with the external environment of the cabin 13, thereby avoiding or reducing the condensation of the external air into the cabin 13 as much as possible, thereby avoiding contamination of the reagents placed in the storage cabin 10, which is beneficial to ensure the quality of the reagents. By setting the air pipe 31 of the pressurizing module 30 toward the refrigeration part 15 in the cabin 13, the air entering the cabin 13 through the air pipe 31 can flow to the refrigeration part 15, thereby achieving rapid cooling, which is beneficial to maintaining the temperature in the cabin 13.

[0079] See also Figure 3The sequencing system 200 provided in the embodiment of the present application includes the reagent storage device 100, the liquid extraction device 210 and the sequencing device 230 in the above embodiment. The reagent storage device 100 is used to store reagents, and the liquid extraction device 210 includes a liquid extraction needle 211, which is used to extract reagents from the reagent storage device 100. The sequencing device 230 is used to sequence the sample.

[0080] The sequencing device 230 is also used to receive the reagent extracted by the liquid extraction needle 211 and to react the reagent with the sample. Specifically, after the sample to be sequenced is placed in the sequencing device 230, it needs to react with the reagent first to facilitate the subsequent sequencing process. The liquid extraction device 210 can be moved between the reagent storage device 100 and the sequencing device 230, so as to transfer the reagent from the reagent storage device 100 to the sequencing device 230.

[0081] The liquid collection device 210 may include only one liquid collection needle 211, or may include multiple liquid collection needles 211. The arrangement positions of the liquid collection needles 211 correspond one-to-one to the positions of the liquid collection needle holes 136 on the chamber 13 of the reagent storage device 100, so that each liquid collection needle 211 can penetrate into the chamber 13 through one liquid collection needle hole 136, thereby extracting the reagent placed in the chamber 13.

[0082] The sequencing device 230 may be a sequencing instrument of any structure, and this application does not impose any limitation on this.

[0083] The sequencing system 200 provided in the embodiment of the present application, by adopting the reagent storage device 100 in the above-mentioned embodiment, can reduce the condensation of condensed water by pressurizing the storage compartment 10, thereby preventing the reagents placed in the storage compartment 10 from being contaminated by condensed water, which is beneficial to ensuring the quality of the reagents and further ensuring the quality of sequencing.

[0084] Those skilled in the art should recognize that the above embodiments are only used to illustrate the present application and are not intended to be limiting of the present application. As long as they are within the spirit and scope of the present application, appropriate changes and modifications to the above embodiments are within the scope of protection claimed in the present application.

Claims

1. A reagent storage device, characterized in that: include: A storage cabin, comprising a cabin door, a refrigeration unit and a cabin body, wherein the refrigeration unit is arranged in the cabin body, and the cabin door and the cabin body together constitute a receiving cavity for receiving reagents; A pressurizing module, comprising an air pipe and an air pump, wherein the air pump is arranged outside the cabin, the air pipe is communicated with the air pump and penetrates the cabin to connect the inside and outside of the cabin, and one end of the air pipe located in the cabin is arranged toward the refrigeration unit; as well as The drainage module comprises a drainage pipe, wherein the drainage pipe is at least partially arranged outside the cabin and communicated with the inside of the cabin, and the drainage pipe is used to discharge the condensed water in the cabin.

2. The reagent storage device according to claim 1, characterized in that: The pressurizing module also includes an air filter unit, which is connected to an end of the air pump away from the cabin. The air filter unit includes an impurity filter module, which is used to filter impurities in the air.

3. The reagent storage device according to claim 2, characterized in that: The air filter unit further includes a dehumidification module, and the dehumidification module is used to filter moisture in the air.

4. The reagent storage device according to claim 1, characterized in that: The pressurizing module further includes a pressure sensing unit, which is disposed in the cabin and is used to sense the air pressure in the cabin.

5. The reagent storage device according to claim 4, characterized in that: The pressurizing module also includes a control unit, which is electrically connected to the pressure sensing unit and the air pump, and is used to control the switch of the air pump according to the air pressure sensed by the pressure sensing unit.

6. The reagent storage device according to claim 1, characterized in that: The drainage module also includes a liquid pump, which is arranged on the outside of the cabin and communicated with the drainage pipe for extracting moisture from the cabin.

7. The reagent storage device according to claim 1, characterized in that: The drainage module also includes a collection box, which is arranged on the outside of the cabin and communicated with the drainage pipe, and is used to collect the water discharged from the cabin by the drainage pipe.

8. The reagent storage device according to claim 1, characterized in that: A drainage groove and a drainage port are provided on the bottom wall of the cabin body. The drainage groove is communicated with the drainage port, and the drainage port is communicated with the drainage pipe.

9. The reagent storage device according to claim 1, characterized in that: The top wall of the cabin is also provided with a liquid collection needle hole, and the liquid collection needle hole is used to connect the inner and outer sides of the cabin.

10. A sequencing system, characterized in that: include: The reagent storage device according to any one of claims 1 to 9, wherein the reagent storage device is used to store reagents; A liquid extraction device, comprising a liquid extraction needle, wherein the liquid extraction needle is used to extract the reagent from the reagent storage device; as well as The sequencing device is used to sequence the sample. The sequencing device is also used to receive the reagent extracted by the liquid collection needle and to make the reagent react with the sample.