Freezing tube filling machine

By designing an automated frozen storage tube filling machine, the problems of inefficiency and difficulty in ensuring accuracy in the traditional frozen storage tube filling process are solved, and efficient and accurate automatic filling is achieved, reducing the risk of contamination and loss of biological samples.

CN222556576UActive Publication Date: 2025-03-04GUANGZHOU YONGZHUO MASCH EQUIP CO LTD
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202420906740.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-28
Publication Date
2025-03-04
Estimated Expiration
2034-04-28

AI Technical Summary

Technical Problem

The filling process of traditional frozen storage tubes requires manual operation, which is inefficient, and long-term operation leads to muscle fatigue, making it difficult to ensure accuracy, and easily leads to contamination or loss of biological samples.

Method used

A frozen storage tube filling machine is designed, including a bracket, a control machine, a conveying mechanism and a filling mechanism. Through an automated xyz three-axis mobile station and precise liquid filling control, the automatic bottle top, lower bottle and liquid filling of the frozen storage tube is realized.

Benefits of technology

It improves the automation of the filling process, reduces manual operation, reduces operation difficulty, ensures filling accuracy, reduces the risk of biological sample contamination and loss, and improves production efficiency.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN222556576U_ABST
    Figure CN222556576U_ABST
Patent Text Reader

Abstract

The utility model discloses a cryopreservation tube filling machine, relates to the technical field of filling equipment, and provides the following scheme aiming at the problems that the precision is difficult to guarantee and even biological samples are polluted or lost due to muscle fatigue and the like when an arm is lifted for filling for a long time in the prior art: the cryopreservation tube filling machine comprises a bracket, a control machine is arranged on one side of the support, containing discs are symmetrically arranged above the middle of the support in parallel, a conveying mechanism is connected to one side of the interior of the support and electrically connected with the control machine, a filling mechanism is arranged in the portion, between the two containing discs, of the support, and the filling mechanism is electrically connected with the control machine. The filling mechanism is matched with the conveying mechanism to be used for filling a preset amount of liquid into the cryopreservation tubes, the automatic grabbing device is novel in structure and high in automation degree, the cryopreservation tubes can be automatically grabbed, and bottle feeding and bottle discharging actions can be stably carried out on the filling mechanism for a long time.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The utility model relates to the technical field of filling equipment, in particular to a freezing tube filling machine. Background Art

[0002] Nowadays, cryopreservation tubes are widely used in the fields of biotechnology, medicine, scientific research, etc. to store cells, tissues or biological samples;

[0003] The traditional process of filling cryotubes mostly requires manual operation, which is not only inefficient, but also when the arms are raised for a long time to fill, the operator will suffer from muscle fatigue, etc., which makes it difficult to ensure accuracy and may even cause contamination or loss of biological samples. Utility Model Content

[0004] The cryopreservation tube filling machine provided by the utility model solves the existing problems.

[0005] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a cryopreservation tube filling machine, including a bracket, a control machine is arranged on one side of the bracket, and the bracket is a square frame structure, a placement tray is arranged parallel and symmetrically above the middle part of the bracket, a conveying mechanism is connected to one side of the inside of the bracket, the conveying mechanism is electrically connected to the control machine, the conveying mechanism is used to automatically load and unload the cryopreservation tubes placed on the placement tray, a filling mechanism is arranged inside the bracket between the two placement trays, the filling mechanism is electrically connected to the control machine, and the filling mechanism cooperates with the conveying mechanism to fill a preset amount of liquid into the cryopreservation tube.

[0006] Preferably, a working plate is provided inside the bracket, a mounting plate is connected to the inner side of the bracket on one side above the working plate, and the mounting plate is connected to the conveying mechanism, and a placing plate is provided in the middle of the upper end of the working plate.

[0007] Preferably, the conveying mechanism includes a first electric box, and an empty slot is opened inside the first electric box, sliding rods are connected to the upper and lower ends of the first electric box, a first rotating rod is connected to the middle of the sliding rod, and the other end of the first rotating rod is connected to a first motor, the sliding rod and the first rotating rod are externally connected to a first connecting plate, and a keel is connected above the first connecting plate.

[0008] Preferably, a connecting plate is connected to one side of the first linkage plate, and a second electric box is connected to one side of the connecting plate, and a second motor is arranged on the upper end thereof, a second linkage plate is connected inside the second electric box, and a third electric box is connected to one side of the second linkage plate, a third motor is arranged at one end of the third electric box, and a third linkage plate is connected inside the third electric box, a long plate is connected to one side of the third linkage plate, a fourth electric box is connected to one side of the long plate, a second rotating rod is arranged inside the fourth electric box, two grippers are connected to the outer end of the second rotating rod in parallel, the two grippers move relative to each other, a detection light eye is arranged between the grippers below the fourth electric box, and a fourth motor is connected to one end of the second rotating rod.

[0009] Preferably, the filling mechanism includes a square plate and a metering pump, a fifth motor is connected to one side of the square plate, a turntable is connected above the fifth motor, two bottle grabbing clamps are symmetrically connected to both ends of one side above the square plate, a third rotating rod is connected to the middle of the turntable, a sixth motor is connected to the lower end of the third rotating rod, and an electric capping plate is connected to the upper end of the third rotating rod.

[0010] Preferably, bottle loading photoeyes are arranged around the inside of the turntable, capping photoeyes are arranged on both sides of the two bottle grabbing clamps around the turntable, filling photoeyes are arranged on one side of the turntable corresponding to the metering pump, lower bottle photoeyes are arranged on the side of the turntable opposite to the upper bottle photoeye, and origin photoeyes are arranged on the side of the turntable opposite to the filling photoeye.

[0011] The beneficial effects of the utility model are as follows: the degree of automation is high, the device forms an xyz three-axis moving platform through the coordinated movement of the first electric box, the second electric box and the third electric box, and the two grippers are driven to move relative to each other by the rotation of the second rotating rod, so that the cryogenic tube can be automatically grasped, and the filling mechanism can stably carry out the bottle loading and unloading actions for a long time; the device facilitates the upper and lower bottle positioning of the conveying mechanism through the upper bottle photoeye and the lower bottle photoeye arranged inside the turntable, and the filling of the cryogenic tube by the filling photoeye can accurately control the filling amount of the liquid in conjunction with the metering pump, so as to meet the strict requirements of biological sample storage and improve production efficiency; the capping photoeye and the bottle grabbing clamp can quickly realize the operation of removing the cap before filling and screwing the cap after filling of the cryogenic tube, so as to reduce the probability of foreign object contamination; the automatic operation of the entire filling process is realized by the control machine, so that manual operation is reduced and the operation difficulty is reduced. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 It is a structural schematic diagram of the utility model.

[0013] Figure 2 It is a schematic diagram of the bracket of the utility model.

[0014] Figure 3 This is a disassembled diagram of the transmission mechanism of the utility model.

[0015] Figure 4 This is a disassembled diagram of the transmission mechanism of the utility model from another perspective.

[0016] Figure 5 It is a schematic diagram of the filling mechanism of the utility model.

[0017] Figure 6 This is a schematic diagram of the filling mechanism of the utility model from another perspective.

[0018] Numbers in the figure: 1, bracket; 101, working plate; 102, mounting plate; 2, control machine; 3, placement plate; 4, transmission mechanism; 401, first electric box; 402, sliding rod; 403, first rotating rod; 404, first motor; 405, first linkage plate; 406, keel; 407, connecting plate; 408, second electric box; 409, second motor; 410, second linkage plate; 411, third electric box; 412, third motor; 413, third linkage plate ; 414, long board; 415, fourth electric box; 416, second rotating rod; 417, gripper; 418, fourth motor; 5, filling mechanism; 501, square plate; 502, metering pump; 503, fifth motor; 504, turntable; 505, bottle grabbing clamp; 506, third rotating rod; 507, sixth motor; 508, electric capping plate; 509, bottle loading light eye; 510, capping light eye; 511, filling light eye; 512, bottle unloading light eye; 513, origin light eye. DETAILED DESCRIPTION

[0019] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0020] Reference Figure 1-Figure 6 The cryopreservation tube filling machine includes a bracket 1, a control machine 2 is arranged on one side of the bracket 1, and the bracket 1 is a square frame structure, a placement tray 3 is arranged parallel and symmetrically above the middle part of the bracket 1, a conveying mechanism 4 is connected to one side of the inside of the bracket 1, and the conveying mechanism 4 is electrically connected to the control machine 2. The conveying mechanism 4 is used to automatically load and unload the cryopreservation tubes placed on the placement tray 3, and a filling mechanism 5 is arranged inside the bracket 1 between the two placement trays 3. The filling mechanism 5 is electrically connected to the control machine 2, and the filling mechanism 5 cooperates with the conveying mechanism 4 to fill a preset amount of liquid into the cryopreservation tube, a working plate 101 is arranged inside the bracket 1, and a mounting plate 102 is connected to the inner side of the bracket 1 on one side above the working plate 101, and the mounting plate 102 is connected to the conveying mechanism 4, and a placement tray 3 is arranged in the middle of the upper end of the working plate 101.

[0021] Reference Figure 3 , Figure 4The transmission mechanism 4 includes a first electric box 401, and an empty slot is opened inside the first electric box 401, and the upper and lower ends of the first electric box 401 are connected to sliding rods 402, and the middle of the sliding rod 402 is connected to a first rotating rod 403, and the other end of the first rotating rod 403 is connected to a first motor 404, and the sliding rod 402 and the first rotating rod 403 are connected to the outside of the first linkage plate 405, and the top of the first linkage plate 405 is connected to a keel 406, and one side of the first linkage plate 405 is connected to a connecting plate 407, and one side of the connecting plate 407 is connected to a second electric box 408. The upper end is provided with a second motor 409, and the second electric box 408 is connected to a second linkage plate 410, and the second linkage plate 410 is connected to a third electric box 411. One end of the third electric box 411 is provided with a third motor 412, and the third electric box 411 is connected to a third linkage plate 413, and one side of the third linkage plate 413 is connected to a long plate 41 4. A fourth electric box 415 is connected to one side below the long board 414, and a second rotating rod 416 is arranged inside the fourth electric box 415. Two grippers 417 are connected to the outer end of the second rotating rod 416 in parallel, and the two grippers 417 move relative to each other. A detection light eye is arranged between the grippers 417 below the fourth electric box 415, and a fourth motor 418 is connected to one end of the second rotating rod 416. The conveying mechanism 4 can automatically grab the cryopreservation tube and place it at a predetermined position, and the gripper 417 is driven to move left and right by the first rotating rod 403 inside the first electric box 401. Similarly, the gripper 417 is moved forward and backward by the rotating rod inside the second electric box 408, and the gripper 417 is moved up and down by the rotating rod inside the third electric box 411. The position and state of the cryopreservation tube are detected by the detection light eye at the lower end of the fourth electric box 415 to ensure the accuracy and stability of conveying and filling.

[0022] Reference Figure 5 , Figure 6The filling mechanism 5 includes a square plate 501 and a metering pump 502. A fifth motor 503 is connected to one side of the square plate 501. A turntable 504 is connected above the fifth motor 503. Two bottle grabbing clamps 505 are symmetrically connected to both ends of one side above the square plate 501. A third rotating rod 506 is connected to the middle of the turntable 504. A sixth motor 507 is connected to the lower end of the third rotating rod 506. An electric capping disk 508 is connected to the upper end of the third rotating rod 506. Bottle loading photoeyes 509 are arranged around the turntable 504. Capping photoeyes 510 are arranged on both sides of the turntable 504 corresponding to the two bottle grabbing clamps 505. A bottle loading light eye 510 is arranged around the turntable 504 corresponding to one side of the metering pump 502. Filling photoeye 511, lower bottle photoeye 512 is arranged on the side of the turntable 504 opposite to the upper bottle photoeye 509, and origin photoeye 513 is arranged on the side of the turntable 504 opposite to the filling photoeye 511. The metering pump 502 in the filling mechanism 5 adopts high-precision flow control technology to accurately control the flow and speed of the liquid, and cooperates with the filling photoeye 511 on the turntable 504 to ensure that the liquid flows smoothly into the cryopreservation tube. The upper bottle photoeye 509, capping photoeye 510, filling photoeye 511, lower bottle photoeye 512 and origin photoeye 513 on the turntable 504 are used to identify the position of the cryopreservation tube and perform corresponding operations to avoid waste and pollution.

[0023] Working principle: First, place the filled cryopreservation tube on a placement tray 3, connect and control the conveying mechanism 4 and the filling mechanism 5 through the control machine 2, start the first motor 404, the second motor 409 and the third motor 412 to drive the gripper 417 to move randomly in the xyz three axes, detect the position of the cryopreservation tube through the detection photoeye under the fourth electric box 415, and start the fourth motor 418 to rotate the second rotating rod 416 to move the gripper 417 to clamp the cryopreservation tube;

[0024] Next, the cryopreservation tube is moved to the upper bottle photoeye 509 on the turntable 504, the fifth motor 503 is rotated to rotate the turntable 504 to the square plate 501, the cryopreservation tube is fixed by the bottle grabbing clamp 505, the upper cover of the cryopreservation tube is removed by the electric capping disk 508, the bottle grabbing clamp 505 is sent away, the fifth motor 503 is started to rotate the turntable 504 to the filling photoeye 511, and the metering pump 502 is started to fill the cryopreservation tube. After the end, the fifth motor 503 is started again to rotate the turntable 504 to another capping photoeye 510, and the bottle grabbing clamp 505 is started to cooperate with the electric capping disk 508 to screw the cap, the bottle grabbing clamp 505 is closed, and the fifth motor 503 is started to rotate the turntable 504 to the lower bottle photoeye 512. Finally, the filled cryopreservation tube is taken out by the conveying mechanism 4 and placed on another placement disk 3 to complete the entire filling process.

[0025] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A cryotube filling machine, comprising a support (1), characterized in that: A control machine (2) is arranged on one side of the support (1), and the support (1) is a cubic frame structure. A placement tray (3) is arranged parallel and symmetrically above the middle of the support (1). A conveying mechanism (4) is connected to one side of the interior of the support (1). The conveying mechanism (4) is electrically connected to the control machine (2). The conveying mechanism (4) is used to automatically load and unload the cryopreservation tubes placed on the placement tray (3). A filling mechanism (5) is arranged inside the support (1) between the two placement trays (3). The filling mechanism (5) is electrically connected to the control machine (2), and the filling mechanism (5) cooperates with the conveying mechanism (4) to fill a preset amount of liquid into the cryopreservation tube.

2. The cryotube filling machine according to claim 1, characterized in that: A working plate (101) is arranged inside the bracket (1), a mounting plate (102) is connected to the inner side of the bracket (1) above the working plate (101), and the mounting plate (102) is connected to the conveying mechanism (4), and a placement plate (3) is arranged in the middle of the upper end of the working plate (101).

3. The cryotube filling machine according to claim 1, characterized in that: The transmission mechanism (4) comprises a first electric box (401), and an empty slot is opened inside the first electric box (401), the upper and lower ends of the first electric box (401) are connected with sliding rods (402), the middle of the sliding rod (402) is connected with a first rotating rod (403), and the other end of the first rotating rod (403) is connected with a first motor (404), the sliding rod (402) and the first rotating rod (403) are externally connected with a first linkage plate (405), and the top of the first linkage plate (405) is connected with a keel (406).

4. The cryotube filling machine according to claim 3, characterized in that: One side of the first linkage plate (405) is connected to a linkage plate (407), and one side of the linkage plate (407) is connected to a second electric box (408) having a second motor (409) disposed on its upper end, the second electric box (408) is internally connected to a second linkage plate (410), and one side of the second linkage plate (410) is connected to a third electric box (411), one end of the third electric box (411) is provided with a third motor (412), and the third electric box (411) is internally connected to a third linkage plate (413), One side of the third linkage plate (413) is connected to a long plate (414), and one side below the long plate (414) is connected to a fourth electric box (415). A second rotating rod (416) is arranged inside the fourth electric box (415), and two clamping hands (417) are connected in parallel to the outer end of the second rotating rod (416). The two clamping hands (417) move relative to each other, and a detection light eye is arranged between the clamping hands (417) below the fourth electric box (415), and one end of the second rotating rod (416) is connected to a fourth motor (418).

5. The cryotube filling machine according to claim 1, characterized in that: The filling mechanism (5) comprises a square plate (501) and a metering pump (502); a fifth motor (503) is connected to one side of the square plate (501); a rotating disk (504) is connected above the fifth motor (503); two bottle grabbing clamps (505) are symmetrically connected to both ends of one side above the square plate (501); a third rotating rod (506) is connected to the middle of the rotating disk (504); a sixth motor (507) is connected to the lower end of the third rotating rod (506); and an electric capping disk (508) is connected to the upper end of the third rotating rod (506).

6. The cryotube filling machine according to claim 5, characterized in that: Bottle loading photoeyes (509) are arranged around the rotating disk (504), capping photoeyes (510) are arranged on both sides of the rotating disk (504) corresponding to the two bottle grabbing clamps (505), filling photoeyes (511) are arranged on one side of the rotating disk (504) corresponding to the metering pump (502), lower bottle photoeyes (512) are arranged on the side of the rotating disk (504) opposite to the bottle loading photoeye (509), and origin photoeyes (513) are arranged on the side of the rotating disk (504) opposite to the filling photoeyes (511).