Serum mixing device with cleaning and sterilizing functions

By designing a serum mixing device with cleaning and sterilization function, the existing serum mixing tanks have been solved, and automated cleaning and sterilization have been achieved, and the efficiency and reliability of the serum mixing process have been improved.

CN222586376UActive Publication Date: 2025-03-11INNER MONGOLIA OPTIMUS BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202520036556.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-01-08
Publication Date
2025-03-11
Estimated Expiration
2035-01-08

AI Technical Summary

Technical Problem

Existing serum mixing tanks are inefficient and poorly effective during cleaning, and lack automation and sterilization functions.

Method used

A serum mixing device with cleaning and sterilization function is designed, including a serum mixing tank and a cleaning and sterilization device in communication with it. The device realizes an automated cleaning and sterilization process through spray cleaning of pure water and alkaline water, combined with SIP sterilization mechanism.

Benefits of technology

It significantly improves the efficiency, safety and reliability of the serum mixing process, ensures efficient cleaning and sterilization of the serum mixing tank, and avoids the inadequacy of manual cleaning.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a serum mixing device with cleaning and sterilizing functions, which belongs to the field of serum mixing and comprises a serum mixing tank and cleaning and sterilizing equipment communicated with the serum mixing tank, the cleaning and sterilizing equipment comprises a pure water tank, an alkaline water tank and an SIP (Session Initiation Protocol) sterilizing mechanism, the pure water tank and the alkaline water tank are respectively communicated with a cleaning and disinfecting opening formed in the top end of the serum mixing tank through a pure water pipe and an alkaline water pipe, and the pure water pipe and the alkaline water pipe are respectively provided with a pumping pump; the SIP sterilization mechanism is communicated with a feeding port formed in the top end of the serum mixing tank and two cleaning and disinfecting holes, the feeding port is communicated with the top end of a feeding pipe, the bottom end of the feeding pipe extends into the serum mixing tank, and a circulation channel is reserved between the end, extending into the serum mixing tank, of the feeding pipe and the inner wall of the bottom end of the serum mixing tank. According to the serum mixing device with the cleaning and sterilizing functions, pure water and alkaline water are provided through the pure water tank and the alkaline water tank respectively, and the situation that the cleaning effect is reduced due to solution mixing is avoided.
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Description

Technical Field

[0001] The utility model relates to the technical field of serum mixing, in particular to a serum mixing device with cleaning and sterilization functions. Background Art

[0002] A serum mixing tank is a device used to mix and store serum in the biopharmaceutical and medical fields. It is usually designed to ensure that the serum remains homogeneous and stable during the mixing process and can meet specific process requirements.

[0003] The existing serum mixing tank is generally cleaned manually, which has the defects of low cleaning efficiency and poor cleaning effect. Utility Model Content

[0004] The utility model aims to provide a serum mixing device with cleaning and sterilizing functions to solve the above technical problems.

[0005] To achieve the above-mentioned purpose, the utility model provides a serum mixing device with cleaning and sterilizing functions, comprising a serum mixing tank and a cleaning and sterilizing device connected to the serum mixing tank, the cleaning and sterilizing device comprising a pure water tank, an alkaline water tank and a SIP sterilizing mechanism, the pure water tank and the alkaline water tank are respectively connected to a cleaning and sterilizing port opened at the top of the serum mixing tank through a pure water pipe and an alkaline water pipe, and a pumping pump is arranged on the pure water pipe and the alkaline water pipe;

[0006] The SIP sterilization mechanism is connected to the feed port and two cleaning and disinfection holes opened at the top of the serum mixing tank. The feed port is connected to the top of the feeding tube. The bottom end of the feeding tube extends into the interior of the serum mixing tank. A flow channel is left between the end of the feeding tube extending into the interior of the serum mixing tank and the inner wall of the bottom end of the serum mixing tank.

[0007] Preferably, a double-layer annular hole is provided at the top of the serum mixing tank, and the double-layer annular hole includes an inner annular hole and an outer annular hole, wherein the inner annular hole includes two cleaning and disinfection holes arranged axially symmetrically, and the two cleaning and disinfection holes are both connected to the top of the cleaning and disinfection tube, and the bottom end of the cleaning and disinfection tube is extended into the serum mixing tank and connected to the spray head;

[0008] The outer ring hole includes a feed port, a pressure gauge port, a first differential pressure level gauge port, a bursting disc port, a safety valve port, a respirator port, a first spare port, a first split sight glass installation port, a second split sight glass installation port, and a second spare port arranged in a circumferential array;

[0009] A discharge port is arranged at the center position of the bottom end of the serum mixing tank. A second differential pressure level gauge port, a thermometer port and a sewage port are also arranged at the bottom end of the serum mixing tank. The sewage port is connected to one end of a sewage pipe. A conductivity meter and a first temperature sensor are respectively arranged at the other end of the sewage pipe. The conductivity meter and the first temperature sensor are respectively electrically connected to the pumping pump and the SIP sterilization mechanism through a PLC controller.

[0010] Preferably, the tank body of the serum mixing tank is a double-layer structure, the serum mixing tank includes an outer layer and an inner layer, a refrigerant flow channel is left between the outer layer and the inner layer, one end of the refrigerant flow channel is connected to the refrigerant inlet opened at the bottom end of the serum mixing tank, and the other end is connected to the refrigerant outlet opened at the top end of one side of the serum mixing tank, and the refrigerant inlet and the refrigerant outlet are both connected to the refrigerator;

[0011] A second temperature sensor is also provided inside the refrigerant flow channel, and the second temperature sensor is electrically connected to the refrigerator via a PLC controller.

[0012] Preferably, a weight scale is provided at the bottom end of the serum mixing tank and the bottom end of the alkaline water tank.

[0013] Preferably, an electromagnetic stirring mechanism is provided at the bottom end of the serum mixing tank.

[0014] Preferably, the outer wall of the feeding tube located inside the serum mixing tank is positioned and connected to the side wall of the serum mixing tank via a suspension rod.

[0015] Therefore, the utility model adopts the above-mentioned serum mixing device with cleaning and sterilization function, which has the following beneficial effects:

[0016] Through its multi-functional interface design, efficient cleaning and sterilization system, precise temperature control and metering, uniform mixing mechanism and automated control system, the efficiency, safety and reliability of the serum mixing process are significantly improved.

[0017] The technical solution of the utility model is further described in detail below through the accompanying drawings and embodiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a layout diagram of a serum mixing device with cleaning and sterilization functions of the utility model;

[0019] Figure 2 The utility model is a top view of a serum mixing device with cleaning and sterilization functions.

[0020] Reference numerals

[0021] 1. Pure water tank; 11. Pure water pipe; 2. Serum mixing tank; 21. Feeding pipe; 22. Cleaning and disinfection pipe; 23. Electromagnetic stirring mechanism; 24. Weight scale; 25. Refrigerant inlet; 26. Second temperature sensor; 27. Refrigerant outlet; 28. Pressure gauge port; 29. ​​Cleaning and disinfection hole; 210. First differential pressure level gauge port; 211. Bursting disc port; 212. Safety valve port; 213. Respirator port; 214. First spare port; 215. First split sight glass installation port; 216. Second split sight glass installation port; 217. Second spare port; 218. Discharge port; 219. Feed port; 3. SIP sterilization mechanism; 4. Alkaline water tank; 41. Alkaline water pipe. DETAILED DESCRIPTION

[0022] In the description of the present utility model, it should be noted that the terms "upper", "lower", "inside", "outside", etc. indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, or the positions or positional relationships in which the utility model product is usually placed when in use, and are only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific position, be constructed and operated in a specific position, and therefore cannot be understood as a limitation on the present utility model. In the description of the present utility model, it should also be noted that, unless otherwise clearly specified and limited, the terms "set", "install", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be a connection between the two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific circumstances.

[0023] The following is a detailed description of the embodiments of the present invention in conjunction with the accompanying drawings.

[0024] like Figure 1 and Figure 2 As shown, a serum mixing device with cleaning and sterilization functions includes a serum mixing tank 2 and a cleaning and sterilization device connected to the serum mixing tank 2, the cleaning and sterilization device includes a pure water tank 1, an alkaline water tank 4 and a SIP sterilization mechanism 3, the pure water tank 1 and the alkaline water tank 4 are respectively connected to the cleaning and disinfection port opened at the top of the serum mixing tank 2 through a pure water pipe 11 and an alkaline water pipe 41, and a pumping pump is provided on the pure water pipe 11 and the alkaline water pipe 41; the SIP sterilization mechanism 3 is connected to the feed port and two cleaning and disinfection holes opened at the top of the serum mixing tank 2, the feed port is connected to the top of the feeding pipe 21, the bottom end of the feeding pipe 21 extends into the interior of the serum mixing tank 2, and a flow channel is left between the end of the feeding pipe 21 extending into the interior of the serum mixing tank 2 and the inner wall of the bottom end of the serum mixing tank 2.

[0025] A double-layer annular hole is provided at the top of the serum mixing tank 2, and the double-layer annular hole includes an inner annular hole and an outer annular hole, wherein the inner annular hole includes two cleaning and disinfection holes 29 arranged axially symmetrically, and the two cleaning and disinfection holes 29 are both connected to the top of the cleaning and disinfection tube 22, and the bottom end of the cleaning and disinfection tube 22 is extended into the serum mixing tank 2 and connected to the spray head; the outer annular hole includes a feed port 219, a pressure gauge port 28, a first differential pressure level gauge port 210, a bursting disc port 211, a safety valve port 212, a respirator port 213, a first differential pressure level gauge port 214, a first differential pressure level gauge port 215, a first differential pressure level gauge port 216, a first differential pressure level gauge port 217, a first differential pressure level gauge port 218, a first differential pressure level gauge port 219, a first differential pressure level gauge port 219, a first differential pressure level gauge port 219, a first differential pressure level gauge port 211, a first differential pressure level gauge port 211, a first differential pressure level gauge port 212, a first differential pressure level gauge port 213, a first differential pressure level gauge port 214, a first differential pressure level gauge port 215, a first differential pressure level gauge port 216, a first differential pressure level gauge port 217, a first differential pressure level gauge port 218, a first differential pressure level gauge port 219 ... A spare port 214, a first split mirror installation port 215, a second split mirror installation port 216 and a second spare port 217; a discharge port 218 is arranged at the center position of the bottom end of the serum mixing tank, and the bottom end of the serum mixing tank is also provided with a second differential pressure level gauge port, a thermometer port and a sewage outlet, the sewage outlet is connected with one end of the sewage pipe, and the other end of the sewage pipe is respectively provided with a conductivity meter and a first temperature sensor, the conductivity meter and the first temperature sensor are respectively electrically connected to the pumping pump and the SIP sterilization mechanism 3 through the PLC controller.

[0026] The tank body of the serum mixing tank 2 is a double-layer structure. The serum mixing tank 2 includes an outer layer and an inner layer. A refrigerant circulation channel is left between the outer layer and the inner layer. One end of the refrigerant circulation channel is connected to the refrigerant inlet 25 opened at the bottom end of the serum mixing tank 2, and the other end is connected to the refrigerant outlet 27 opened at the top of one side of the serum mixing tank 2. The refrigerant inlet 25 and the refrigerant outlet 27 are both connected to the refrigerator; a second temperature sensor 26 is also arranged inside the refrigerant circulation channel, and the second temperature sensor 26 is electrically connected to the refrigerator via a PLC controller.

[0027] It should be noted that the above-mentioned electronic components are mature products on the market. This embodiment only needs to purchase them and connect them according to the instructions. No improvement is made to them, so their circuit connection structure and principle will not be described in detail here.

[0028] The bottom end of the serum mixing tank 2 and the bottom end of the alkaline water tank 4 are both provided with a weight scale 24 .

[0029] An electromagnetic stirring mechanism 23 is provided at the bottom end of the serum mixing tank 2 to prevent serum precipitation.

[0030] The outer wall of the feeding tube 21 located inside the serum mixing tank 2 is positioned and connected to the side wall of the serum mixing tank 2 via a suspension rod.

[0031] Cleaning, disinfection and sterilization process: first, empty the serum in the serum mixing tank 2, then open the pure water pipe 11, spray pure water into the serum mixing tank 2 through the two cleaning and disinfection holes 29 and the spray head, use the pure water to pre-clean, and use the sewage pipe to discharge the cleaning sewage; then close the pure water pipe 11, and open the alkaline water pipe 41, spray 2% NaOH solution into the serum mixing tank 2 through the two cleaning and disinfection holes 29 and the spray head for alkaline washing, and use the circulation pump to pump the washed NaOH solution to the alkaline water tank 4; then open the pure water pipe 11 again, Close the alkaline water pipe 41 for flushing, and after the flushing is completed, use a conductivity meter to check whether the set cleaning effect is achieved. If not, continue to wash with pure water until the set cleaning effect is achieved; finally, open the SIP sterilization mechanism 3 (in-situ sterilization) and introduce steam into the serum mixing tank 2 through the two cleaning and disinfection holes 29 and the spray head, and at the same time, intermittently introduce steam into the serum mixing tank 2 through the feed port 219 until the temperature collected by the first temperature sensor reaches the set temperature, start timing, and close the SIP sterilization mechanism 3 until the set time is reached.

[0032] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the utility model rather than to limit it. Although the utility model has been described in detail with reference to the preferred embodiments, ordinary technicians in this field should understand that they can still modify or replace the technical solution of the utility model with equivalents, and these modifications or equivalent replacements cannot cause the modified technical solution to deviate from the spirit and scope of the technical solution of the utility model.

Claims

1. A serum mixing device with cleaning and sterilizing functions, comprising a serum mixing tank and a cleaning and sterilizing device connected to the serum mixing tank, characterized in that: The cleaning and sterilization equipment includes a pure water tank, an alkaline water tank and a SIP sterilization mechanism. The pure water tank and the alkaline water tank are connected to the cleaning and sterilization port opened at the top of the serum mixing tank through a pure water pipe and an alkaline water pipe respectively. Pumping pumps are provided on the pure water pipe and the alkaline water pipe. The SIP sterilization mechanism is connected to a feed port and two cleaning and disinfection holes provided at the top of the serum mixing tank, the feed port is connected to the top of a feed pipe, the bottom end of the feed pipe extends into the interior of the serum mixing tank, and a flow channel is left between the end of the feed pipe extending into the interior of the serum mixing tank and the inner wall of the bottom end of the serum mixing tank; A double-layer ring hole is provided at the top of the serum mixing tank, and the double-layer ring hole includes an inner ring hole and an outer ring hole, wherein the inner ring hole includes two cleaning and disinfection holes arranged axially symmetrically, and the two cleaning and disinfection holes are both connected to the top of the cleaning and disinfection tube, and the bottom end of the cleaning and disinfection tube is extended into the serum mixing tank and connected to the spray head; The outer ring hole includes a feed port, a pressure gauge port, a first differential pressure level gauge port, a bursting disc port, a safety valve port, a respirator port, a first spare port, a first split sight glass installation port, a second split sight glass installation port, and a second spare port arranged in a circumferential array; A discharge port is arranged at the center of the bottom end of the serum mixing tank. A second differential pressure level gauge port, a thermometer port and a sewage outlet are also arranged at the bottom end of the serum mixing tank. The sewage outlet is connected to one end of a sewage pipe. A conductivity meter and a first temperature sensor are arranged at the other end of the sewage pipe. The conductivity meter and the first temperature sensor are electrically connected to the pumping pump and the SIP sterilization mechanism through a PLC controller. The tank body of the serum mixing tank is a double-layer structure, and the serum mixing tank includes an outer layer and an inner layer, and a refrigerant flow channel is left between the outer layer and the inner layer. One end of the refrigerant flow channel is connected to the refrigerant inlet opened at the bottom of the serum mixing tank, and the other end is connected to the refrigerant outlet opened at the top of one side of the serum mixing tank. The refrigerant inlet and the refrigerant outlet are both connected to the refrigerator; A second temperature sensor is also provided inside the refrigerant flow channel, and the second temperature sensor is electrically connected to the refrigerator via a PLC controller.

2. A serum mixing device with cleaning and sterilization function according to claim 1, characterized in that: The bottom of the serum mixing tank and the bottom of the alkaline water tank are both provided with weight scales.

3. A serum mixing device with cleaning and sterilization function according to claim 1, characterized in that: An electromagnetic stirring mechanism is arranged at the bottom end of the serum mixing tank.

4. A serum mixing device with cleaning and sterilization function according to claim 1, characterized in that: The outer wall of the feeding tube located inside the serum mixing tank is positioned and connected with the side wall of the serum mixing tank via a hanging rod.