Cleaning device for cell staining slide preparation

By designing a cleaning device with a slide cleaning chamber and a debris cleaning chamber in a cell staining chip machine, the problem of complex and inefficient cleaning process in the prior art is solved, and rapid cleaning of slides and space savings are achieved.

CN222607491UActive Publication Date: 2025-03-14GUANGZHOU LBP AUTOMATED TESTING EQUIP
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Patent Information

Application Number
CN202420635948.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-03-28
Publication Date
2025-03-14
Estimated Expiration
2034-03-28

AI Technical Summary

Technical Problem

The existing cell staining chip machine cleaning device has a complicated process and a long time, resulting in low efficiency of the entire equipment.

Method used

A cleaning device including a slide cleaning room and a slide debris cleaning room was designed to achieve rapid cleaning of the slides through the flushing channel, and a ladder was installed on the base to save space.

Benefits of technology

The cleaning process of slides is simplified, the efficiency of the entire cell staining machine is improved, and the space of the cleaning device is effectively saved.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a cleaning device for cell staining slide preparation, which comprises a cavity with an opening at the top end, a slide cleaning chamber and a slide fragment cleaning chamber are arranged in the cavity, and the bottom of the slide cleaning chamber is communicated with the bottom of the slide fragment cleaning chamber; and a flushing channel communicated with the slide cleaning chamber is also arranged. And the glass slide is convenient and rapid to clean, so that the efficiency of the whole cell staining slide making machine is improved.
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Description

Technical Field

[0001] The utility model belongs to the technical field of cell slide making, and in particular relates to a cleaning device used for cell staining slide making. Background Art

[0002] In the cell staining equipment, during the staining process, there will be dye and rubber ring residues around the sealing ring of the staining chamber and the slide, which will affect the later reading of the slide. Therefore, it is necessary to clean the slide to remove the residue on the surface of the slide before sealing.

[0003] The current cleaning device has a complicated process and a long cleaning time when cleaning the slide, which makes the efficiency of the entire cell staining machine low. Summary of the invention

[0004] The utility model aims to provide a cleaning device for cell staining slide making, so as to solve the problem that the slide cannot be cleaned simply, conveniently and efficiently.

[0005] The technical solution is as follows:

[0006] The utility model is a cleaning device for cell staining and slide making, comprising:

[0007] The cavity with an opening at the top,

[0008] A glass slide cleaning chamber and a glass slide debris cleaning chamber are provided in the cavity, and the bottom of the glass slide cleaning chamber is communicated with the bottom of the glass slide debris cleaning chamber;

[0009] A flushing channel communicated with the slide cleaning chamber is also provided.

[0010] In one embodiment, the flushing channel includes an inlet provided at the bottom of the slide washing chamber for the inflow of the washing liquid, a vertically arranged first channel and a horizontally arranged second channel, and the inlet, the first channel and the second channel are connected in sequence.

[0011] In one of the embodiments, a plurality of flushing ports connected to the cavity are provided on the second channel, and the center lines of the flushing ports are arranged to be inclined downward.

[0012] In one embodiment, the top edge of the slide cleaning chamber is chamfered.

[0013] In one embodiment, a waste outlet is provided on the bottom surface of the glass chip cleaning chamber, a filter is provided on the waste outlet, and the bottom surface of the inner wall of the glass chip cleaning chamber is inclined toward the waste outlet.

[0014] In one embodiment, two slide cleaning chambers are provided in the cavity.

[0015] In one of the embodiments, it further comprises a base connected to the cavity, the base is provided with at least two steps, the heights of the steps are different, and the top of the steps is provided with a liquid adding needle cleaning groove.

[0016] In one of the embodiments, a channel is provided in the base, which runs through the bottom wall of the base to one of the platforms, and a channel opening on the channel connected to the platform forms a consumables discarding opening.

[0017] In one of the embodiments, a positioning boss is provided on the base, and a positioning groove coupled to the positioning boss is provided on the cavity.

[0018] In one embodiment, the side wall of the base is hollow, and a plurality of threaded holes are provided on the bottom wall of the base.

[0019] The technical solution provided by the utility model has the following advantages and effects:

[0020] A slide cleaning chamber and a slide debris cleaning chamber which are connected at the bottom are arranged in the cavity. The slide placed in the slide cleaning chamber is cleaned through the flushing channel, and then the waste water and slide debris flow into the slide debris cleaning chamber. Cleaning the slide is simple and convenient, thereby improving the efficiency of the entire cell staining slide making machine. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 is a three-dimensional diagram of the cleaning device provided in this embodiment;

[0022] Figure 2 yes Figure 1 A top view of a cleaning device of an embodiment;

[0023] Figure 3 yes Figure 1 A cross-sectional view of a cleaning device of an embodiment;

[0024] Figure 4 is a top view of the second cleaning tank provided in this embodiment;

[0025] Figure 5 yes Figure 4 A cross-sectional view of the second cleaning tank of the embodiment taken along the line AA;

[0026] Figure 6 yes Figure 4 A cross-sectional view taken along line BB of the second cleaning tank of the embodiment.

[0027] Description of reference numerals:

[0028] K10, base, K11, step, K12, positioning boss, K13, screw hole, K14, channel, K15, consumables discard port, K20, first cleaning tank, K30, second cleaning tank, K31, positioning slot, K32, slide cleaning chamber, K32a, cavity, K32b, cleaning interface tube, K32c, flushing port, K32d, chamfer, K32e, first pipeline, K32f, second pipeline, K33, slide debris cleaning chamber, K34, waste outlet, K35, waste outlet pipeline, K36, channel, K37, fixing hole, K40, slide. DETAILED DESCRIPTION

[0029] In order to facilitate the understanding of the present invention, the specific embodiments of the present invention will be described in more detail below with reference to the accompanying drawings.

[0030] Unless otherwise specified or defined, the "first, second..." used in this article is merely used to distinguish names and does not represent a specific quantity or order.

[0031] Unless specifically stated or defined otherwise, the term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0032] It should be noted that, in this document, “fixed to” or “connected to” may mean directly fixing or connecting to an element, or indirectly fixing or connecting to an element.

[0033] When staining cells, the dosing needles and slides need to be cleaned, but the current cleaning device has low space utilization, occupies a large space on the workbench, and increases the size of the cell staining machine. In particular, when performing automated cell staining, multiple dosing needles need to be cleaned at the same time, which occupies a larger workbench space.

[0034] In view of the above problems, the utility model designs a trapezoidal cleaning device, wherein a plurality of steps of different heights are arranged on the base, a first cleaning tank is installed at the top of each step, and then a second cleaning tank is installed near the front step or the rear step, that is, each cleaning device is arranged along the longitudinal gradient, saving space and reducing the size of the cleaning device. The first cleaning tank and the second cleaning tank can both be a liquid-adding needle cleaning tank or a glass slide cleaning tank, which can be selected according to needs.

[0035] In this embodiment, Figure 1 , Figure 2 and Figure 3As shown, in order to improve the cleaning efficiency of the dosing needle, five steps K11 are set on the base K10, and a first cleaning tank K20 is installed on each step K11, and a total of five first cleaning tanks K20 are arranged vertically in a stepped shape. The first cleaning tank K20 is a dosing needle cleaning tank, which is used to clean the sample adding needle on the robot arm, and the second cleaning tank K30 is a glass slide cleaning tank, which is used to clean the glass slide. The shape of the dosing needle cleaning tank is not limited. After a groove matching the shape of the dosing needle cleaning tank is dug on the step K11, the dosing needle cleaning tank can be installed on the step K11 by various methods such as snapping, bonding, etc.

[0036] refer to Figure 2 and Figure 4 In this embodiment, the second cleaning tank K30 is installed next to the front step K11, that is, next to the first cleaning tank K20 with the lowest height, so that space can be saved to the maximum extent. Specifically, the front end of the base K10 extends forward to form a positioning boss K12, and one side of the second cleaning tank K30 is provided with a positioning groove K31 coupled with the positioning boss K12 according to the shape of the positioning boss K12. The second cleaning tank K30 is installed on the base K10 by inserting the positioning boss K12 into the positioning groove K31. The specific shapes of the positioning boss K12 and the positioning groove K31 are not limited and can be set accordingly according to needs.

[0037] The side wall of the base K10 is provided with a through cutout, and the bottom wall of the base K10 is provided with a screw hole K13. The hollowing out of the side wall can reduce the weight of the base K10 and facilitate the screws to pass through the screw holes K13, thereby fixing the base K10 on the workbench. The bottom wall of the second cleaning tank K30 is also provided with a fixing hole K37, which is used to fix the second cleaning tank K30 on the workbench.

[0038] When staining cells and making slides, waste will also be generated, such as used suction nozzles, slide making chambers, etc. In order to facilitate the robot arm to discard these wastes, this embodiment has dug a channel K14 in the base K10 that runs from the bottom wall of the base K10 to the second step K11. The channel K14 is connected to the step K11 to form a consumables discarding port K15. In this embodiment, a guide tube is also provided under the workbench, which is connected to the channel K14. After the robot arm throws the waste into the consumables discarding port K15, it can collect the waste into the collection basket along the channel K14 and the guide tube connected to the channel K14. It should be noted that the consumables discarding port K15 is not limited to the second step K11, and can be opened on any of the steps K11.

[0039] In order to conveniently and quickly clean the slides and improve the efficiency of the entire cell staining machine, the utility model also improves the slide cleaning tank, which can not only conveniently and quickly clean the slides, but also has a simple structure and a smaller size, and can be combined with the liquid adding needle cleaning tank to form a trapezoidal cleaning device, thereby reducing the occupied space of the workbench.

[0040] like Figure 4 , Figure 5 and Figure 6 As shown, the second cleaning tank K30 specifically includes a glass slide cleaning chamber K32 and a glass slide debris cleaning chamber K33. The glass slide cleaning chamber K32 includes a cavity K32a with an opening at the top, and the cavity K32a is used to accommodate the slide K40. The size of the cavity K32a is set according to the size of the slide K40. A flushing channel connected to the cavity K32a is installed on the slide cleaning chamber K32. The bottom of the slide cleaning chamber K32 is connected to the bottom of the slide debris cleaning chamber K33. After the slide K40 is cleaned in the slide cleaning chamber K32, waste water and glass slide debris flow into the slide debris cleaning chamber K33.

[0041] In this embodiment, the slide cleaning chamber K32 is provided with two cavities K32a for cleaning slides in parallel, and two slides K40 can be cleaned at the same time. The slide debris cleaning chamber K33 is located on the right side of the slide cleaning chamber K32. The slide cleaning chamber K32 is connected to the bottom of the slide debris cleaning chamber K33, forming a channel K36 for waste water and slide debris to flow from the slide cleaning chamber K32 to the slide debris cleaning chamber K33. The channel K36 provided at the bottom can make the cleaning water flow more unobstructed. At the same time, since the inflow of the cleaning water flow is greater than the discharge of the water flow after cleaning, the K36 provided at the bottom can also make the slide debris cleaning chamber K33 better play the water storage function to prevent overflow.

[0042] There is a flushing channel for each cavity K32a. The flushing channel mainly includes a cleaning interface tube K32b, a first channel K32e, a second channel K32f and a flushing port K32c. Specifically, there are two cleaning interface tubes K32b below the slide cleaning chamber K32, and a cleaning inlet connected to the cleaning interface tube K32b is provided at the bottom of the slide cleaning chamber K32 for the inflow of cleaning liquid. The cleaning inlet is connected to the vertically arranged first channel K32e to transfer the cleaning liquid to the top of the slide cleaning chamber K32, and the second channel K32f is horizontally arranged along the width direction of the slide K40, and the first channel K32e is connected to the second channel K32f. The first channel K32e is arranged along the vertical plane, and the second channel K32f is arranged along the horizontal plane, and the first channel K32e and the second channel K32f are orthogonal. Then, a flushing port K32c is opened on the second channel K32f to use the cleaning liquid to rinse the slide K40.

[0043] In order to flush more thoroughly, in this embodiment, a plurality of flushing ports K32c connected to the cavity K32a are provided on the second channel K32f, that is, a row of small flushing ports. And the center line of the flushing port K32c is set to be inclined downward. By setting the flushing port K32c to be inclined downward at a small angle, the cross-sectional area of ​​the channel is changed, the flushing force can be increased, and the flushing is cleaner. The inclined downward angle can also reduce water splashing.

[0044] A waste outlet K34 is provided on the bottom surface of the glass chip cleaning chamber K33, and the waste outlet K34 is connected to a waste outlet pipe K35 below the glass chip cleaning chamber K33. A filter is installed on the waste outlet K34 to filter the broken glass to prevent the broken glass from entering the pump and damaging the device. In order to completely discharge the waste liquid, the bottom surface of the inner wall of the glass chip cleaning chamber K33 is designed to be inclined toward the waste outlet K34, and an opening is provided at the top of the glass chip cleaning chamber K33 to facilitate the cleaning of the debris.

[0045] In order to enable the robot to smoothly insert the glass slide K40 into the glass slide cleaning chamber K32 for cleaning, the present embodiment further designs a chamfer K32d on the top edge of the glass slide cleaning chamber K32.

[0046] In summary, by installing multiple liquid-filling needle cleaning tanks on the step platform and installing a glass slide cleaning tank at the front end of the step platform, the space utilization rate is high, saving the space occupied by the cleaning device. The glass slide cleaning tank is designed with a glass slide cleaning chamber and a glass slide debris cleaning chamber connected at the bottom, which makes it simple and convenient to clean the slides. The glass slide cleaning tank adopts a double-cavity design, which can clean multiple slides at the same time; small flushing ports that are tilted downward side by side are also designed on the cavity, which not only makes the glass slide cleaning cleaner, but also reduces water splashing.

[0047] The above embodiments are not exhaustive enumerations based on the present invention, and there may be multiple other implementations not listed. Any replacement and improvement made without violating the concept of the present invention shall fall within the protection scope of the present invention.

Claims

1. A cleaning device for cell staining and slide preparation, characterized in that: include: The cavity with an opening at the top, A glass slide cleaning chamber and a glass slide debris cleaning chamber are provided in the cavity, and the bottom of the glass slide cleaning chamber is communicated with the bottom of the glass slide debris cleaning chamber; A flushing channel communicated with the slide cleaning chamber is also provided.

2. The cleaning device for cell staining and slide preparation according to claim 1, characterized in that: The flushing channel comprises an inlet provided at the bottom of the slide cleaning chamber for the inflow of cleaning liquid, a vertically arranged first channel and a horizontally arranged second channel, and the inlet, the first channel and the second channel are connected in sequence.

3. The cleaning device for cell staining and slide preparation according to claim 2, characterized in that: The second channel is provided with a plurality of flushing ports connected with the cavity, and the center lines of the flushing ports are arranged to be inclined downward.

4. The cleaning device for cell staining and slide preparation according to claim 1, characterized in that: The top edge of the slide cleaning chamber is provided with a chamfer.

5. The cleaning device for cell staining and slide preparation according to claim 1, characterized in that: A waste outlet is arranged on the bottom surface of the glass chip cleaning chamber, a filter screen is arranged on the waste outlet, and the bottom surface of the inner wall of the glass chip cleaning chamber is inclined toward the waste outlet.

6. The cleaning device for cell staining and slide preparation according to claim 1, characterized in that: Two slide cleaning chambers are arranged in the cavity.

7. The cleaning device for cell staining and slide preparation according to claim 1, characterized in that: It also includes a base connected to the cavity, the base is provided with at least two steps, the heights of the steps are different, and the top of the steps is provided with a liquid-filling needle cleaning groove.

8. The cleaning device for cell staining and slide preparation according to claim 7, characterized in that: The base is provided with a passage penetrating from the bottom wall of the base to one of the platforms, and a passage opening on the channel connected to the platform forms a consumables discarding opening.

9. The cleaning device for cell staining and slide preparation according to claim 7, characterized in that: The base is provided with a positioning boss, and the cavity is provided with a positioning groove coupled with the positioning boss.

10. The cleaning device for cell staining and slide preparation according to claim 7, characterized in that: The side wall of the base is hollowed out, and a plurality of threaded holes are arranged on the bottom wall of the base.