Biological sample extraction mechanism for liquid nitrogen tank

Abstract

The utility model discloses a biological sample extraction mechanism for a liquid nitrogen tank. The biological sample extraction mechanism comprises a datum plate, a base, a driving assembly, a storage bin and a lifting cylinder with an opening in the bottom, the datum plate is installed at the top of the tank body and provided with an extraction opening, the base is slidably connected to the datum plate through the driving assembly, a storage bin is arranged on the upper side of the base, a through channel is formed in the bottom of the storage bin, a transfer opening is formed in the side wall of the storage bin, and the bottom of the lifting cylinder is connected with the side wall of the storage bin. The driving assembly drives the base to move so that the channel and the extraction opening can be vertically aligned. A manipulator penetrates through a top plate of the lifting cylinder, extends into the tank body and is connected with the sample basket; the sample basket is moved up and down to drive the lifting cylinder to be folded or unfolded up and down; the base is provided with a shovel plate mechanism aligned with the transfer port, and the cryopreservation box in the sample basket enters and exits from the shovel plate mechanism through the transfer port. The sample storage box is simple in structure and low in manufacturing cost, and independent cooling is not needed during sample storage.

Description

Technical Field

[0001] The utility model relates to the technical field of biological sample extraction, in particular to a biological sample extraction mechanism for a liquid nitrogen tank. Background Art

[0002] The biological sample library is a large-scale device used for long-term low-temperature storage of important biological samples. The samples are generally arranged in cryopreservation boxes and stored in biological sample baskets. The baskets are evenly placed in the liquid nitrogen tank of the biological sample library. When the samples need to be stored and taken out, a special manipulator is used to reach into the liquid nitrogen tank to take out the basket. Due to the large temperature difference between the liquid nitrogen tank and the surrounding environment, if the environment in which the samples are located cannot be in a low-temperature environment, irreversible damage will be caused to the biological samples. In order to reduce the impact of adverse environments on samples, a basket cabin is set on the liquid nitrogen tank or the manipulator, and a cooling component is set in the basket cabin to cool the basket cabin separately so that the temperature in the basket cabin meets the temperature requirements for cryopreservation box storage. The basket cabin is large in size and the manufacturing cost of separate cooling is high. Utility Model Content

[0003] The utility model aims to overcome the shortcomings of the above-mentioned prior art and provide a biological sample extraction mechanism for a liquid nitrogen tank, so as to solve the problems that in the existing liquid nitrogen tank for storing and accessing biological samples, special low-temperature equipment needs to be set up to avoid the influence of freezing and thawing during the process of storing and accessing samples, and the low-temperature structure is complex and costly.

[0004] The technical solution adopted by the utility model to solve its technical problems is:

[0005] A biological sample extraction mechanism for a liquid nitrogen tank comprises a reference plate, a base, a driving assembly, a storage bin, and a lifting cylinder with an opening at the bottom; the reference plate is horizontally mounted on the top of the tank body of the liquid nitrogen tank, and an extraction port for a sample basket to enter and exit the tank body is provided on the reference plate; the base is connected to the reference plate by sliding left and right through the driving assembly, a storage bin is arranged on the upper side of the base, a channel penetrating the base is provided at the bottom of the storage bin, and the driving assembly drives the base to move so that the channel is aligned with the extraction port up and down; a transfer port is provided on the side wall of the storage bin, the bottom of the lifting cylinder is higher than the transfer port and connected to the side wall of the storage bin, and the top plate of the lifting cylinder is pulled up and down to enter and exit the storage bin; a circular hole smaller than the top plane of the sample basket is provided on the top plate of the lifting cylinder; a shovel plate mechanism aligned with the transfer port is installed on the base, and a cryopreservation box in the sample basket enters and exits the shovel plate mechanism from the transfer port.

[0006] Furthermore, the driving assembly includes a guide rail, a driving motor, a gear, and a rack; the guide rail and the rack are installed on the reference plate along the left and right directions, and the base is equipped with a pulley that cooperates with the guide rail; the output end of the driving motor is equipped with a gear that meshes with the rack; and the driving motor is connected to the base.

[0007] Furthermore, the lifting cylinder is a folding cylinder, and the inner side of the folding cylinder is provided with a heat-insulating material; the lifting cylinder is folded in the storage bin.

[0008] Furthermore, the lifting cylinder includes a top plate and several annular covers. The ends of the upper and lower adjacent annular covers are annularly connected to each other, and the inner sides of the annular covers are provided with insulation materials; the top of the annular cover located on the uppermost side is connected to the top plate, and the bottom of the annular cover located on the uppermost side is connected to the side wall of the storage bin.

[0009] Furthermore, the lifting cylinder also includes a scissor-type telescopic member, which includes a hinge shaft, a first connecting rod, and a second connecting rod; the ends of multiple first connecting rods and the ends of second connecting rods are rotatably connected end to end; the middle parts of adjacent first connecting rods and second connecting rods are rotatably connected through a hinge shaft; the hinge shaft located at the bottom is rotatably connected to the storage bin, and the remaining hinge shafts are rotatably connected to the annular cover in sequence.

[0010] The utility model has the following beneficial effects:

[0011] 1. The utility model provides a biological sample extraction mechanism for a liquid nitrogen tank, comprising a reference plate, which is mounted on the top of the tank body, and on which a base, a driving assembly, a storage bin, and a lifting cylinder are arranged; the base is slidably connected to the reference plate through the driving assembly, a storage bin is arranged on the base, and the lifting cylinder is folded in the storage bin, and a manipulator specially used for lifting a sample basket passes through the top plate of the lifting cylinder and extends into the liquid nitrogen tank to connect the sample basket, and then, the top plate of the lifting cylinder is pulled upward by the sample basket, so that the lifting cylinder is unfolded to provide a space with an ambient temperature and humidity that meets the requirements for the sample basket, thereby reducing the freeze-thaw effect on the sample during the sample storage and retrieval process, and the lifting cylinder has a simple structure and does not require additional low-temperature equipment.

[0012] 2. The lifting cylinder adopts a folding cylinder and is provided with heat-insulating materials; or a plurality of annular covers are adopted, and the ends of the annular covers are connected to each other in an annular manner. The structure is simple, the weight is light, and the manufacturing cost is low. The lifting cylinder can be folded in the storage bin and occupies little space.

[0013] 3. A scissor-type telescopic part is set on the side of the lifting cylinder. When the sample basket drives the lifting cylinder to extend and retract up and down, the lifting cylinder can be expanded or retracted at equal intervals up and down, and the movement is uniform and smooth. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] The utility model is further described below in conjunction with the accompanying drawings:

[0015] Figure 1 This is a schematic diagram of the three-dimensional structure of the first embodiment of the utility model;

[0016] Figure 2 It is a top view of the first embodiment of the utility model;

[0017] Figure 3 It is a front view of the first embodiment of the utility model;

[0018] Figure 4 for Figure 1 A partial enlarged view of the middle part;

[0019] Figure 5 for Figure 1 A partial enlarged view of point B in the middle;

[0020] Figure 6 This is a schematic diagram of the structure of the lifting cylinder after unfolding according to the second embodiment of the utility model;

[0021] Figure 7 It is a schematic diagram of the structure of the lifting cylinder after being folded in the second embodiment of the utility model.

[0022] In the figure, 1. tank body; 2. sample basket; 3. reference plate; 31. extraction port; 4. base; 5. drive assembly; 51. guide rail; 52. drive motor; 6. storage bin; 61. transfer port; 7. lifting cylinder; 71. top plate; 72. annular cover; 8. shovel plate mechanism; 9. scissor-type telescopic member; 91. hinge shaft; 92. first connecting rod; 93. second connecting rod. DETAILED DESCRIPTION

[0023] In order to enable those skilled in the art to better understand the technical solution of the present invention, the technical solution of the present invention will be clearly and completely described below in conjunction with the accompanying drawings of the present invention.

[0024] Embodiment 1

[0025] like Figure 1 , 2 As shown in Figure 3, the utility model provides a biological sample extraction mechanism for a liquid nitrogen tank, including a reference plate 3; the reference plate 3 is horizontally installed on the top of the tank body 1 of the liquid nitrogen tank, and an extraction port 31 for the sample basket 2 to enter and exit the tank body 1 is opened on the reference plate 3; a base 4, a driving component 5, a storage bin 6, and a lifting cylinder 7 with an opening at the bottom are arranged on the reference plate 3; the base 4 is connected to the reference plate 3 by sliding left and right through the driving component 5, the storage bin 6 is arranged on the upper side of the base 4, and a channel penetrating the base 4 is opened at the bottom of the storage bin 6, and the driving component 5 drives the base 4 to move so that the channel is aligned with the extraction port 31 up and down;

[0026] A transfer port 61 is provided on the side wall of the storage bin 6, and the bottom of the lifting cylinder 7 is higher than the transfer port 61 and connected to the side wall of the storage bin 6, and the top plate 71 of the lifting cylinder 7 is pulled up and down to enter and exit the storage bin 6; a circular hole smaller than the top plane of the sample basket 2 is provided on the top plate 71 of the lifting cylinder 7; when in use, first open the lid of the liquid nitrogen tank, move the base 4 to align the channel with the extraction port 31, and move the manipulator specially used to lift the sample basket 2 downward through the circular hole, extend into the liquid nitrogen tank, and connect with the top of the sample basket 2; preferably, the connection between the manipulator and the sample basket 2 adopts electromagnetic connection, which is accurate and efficient. Then, the manipulator moves upward to drive the sample basket 2 into the lifting cylinder 7, so that the top of the sample basket 2 contacts the inner side of the top plate 71 of the lifting cylinder 7; after that, the manipulator pulls the sample basket 2 and the top plate 71 of the lifting cylinder 7 upward together, so that the sample basket 2 is completely out of the liquid nitrogen tank and enters the lifting cylinder 7; at this time, the space inside the lifting cylinder 7 and the liquid nitrogen tank are connected, ensuring that the process of lifting the sample basket 2 is always maintained in a temperature and humidity environment that meets the requirements, thereby ensuring the quality of the sample.

[0027] A shovel mechanism 8 aligned with the transfer port 61 is installed on the base 4, and the cryobox in the sample basket 2 enters and exits the shovel mechanism 8 from the transfer port 61; the shovel mechanism 8 includes a receiving box with a top opening, a shovel driver and a shovel. When the sample basket 2 enters the lifting cylinder 7, the cryobox in the sample basket 2 and the transfer port 61 are adjusted up and down, and then the shovel driver can drive the shovel through the transfer port 61 to shovel the cryobox into the receiving box; similarly, the shovel mechanism 8 can complete the work of shoveling the cryobox into the sample basket 2. The shovel mechanism 8 adopts the existing technology and will not be described in detail here. The shovel mechanism 8 not only completes the sample in and out of the sample basket 2, but also serves as a transfer station for the sample in and out of the liquid nitrogen tank.

[0028] like Figure 2 As shown, the driving assembly 5 includes a guide rail 51, a driving motor 52, a gear, and a rack; the guide rail 51 and the rack are installed on the reference plate 3 along the left and right direction, and the base 4 is installed with a pulley that cooperates with the guide rail 51; the output end of the driving motor 52 is installed with a gear that meshes with the rack; the driving motor 52 is connected to the base 4, and through the rotation of the driving motor 52, it is transmitted through the gear rack and converted into left and right movement of the base 4.

[0029] like Figure 4 , 5 As shown, the lifting cylinder 7 is a folding cylinder, and the inner side of the folding cylinder is provided with a heat-insulating material; the lifting cylinder 7 is folded in the storage bin 6 by gravity. The sample basket 2 is pulled upward or downward to drive the top plate 71 of the lifting cylinder 7 to move upward or downward, and the folding part of the lifting cylinder 7 is adaptively retracted; the lifting cylinder 7 surrounds the sample basket 2, providing it with a moving space that meets the temperature and humidity requirements. The folding structure of the cylinder is simple, light, and low in cost, and no additional low-temperature equipment is required.

[0030] Embodiment 2

[0031] The difference between the second embodiment and the first embodiment lies in the lifting cylinder, and the specific contents are as follows: Figure 6 , 7 As shown, the lifting cylinder 7 includes a top plate 71 and a plurality of annular covers 72. The ends of the annular covers 72 adjacent to each other are annularly connected. The inner side of the annular covers 72 is provided with a heat-insulating material. The top of the annular cover 72 located at the uppermost side is connected to the top plate 71, and the bottom of the annular cover 72 located at the uppermost side is connected to the side wall of the storage bin 6. The material of the annular cover 72 is preferably made of thin steel plate. The upper and lower ends of the annular cover 72 are provided with a clamping strip and a clamping groove structure. After the lifting cylinder 7 is fully extended upward, the clamping strips and clamping grooves on the adjacent annular covers 72 are clamped, and the clamping strips and clamping grooves play a limiting role. When the lifting cylinder 7 is folded downward, the clamping strips and clamping grooves on the adjacent annular covers 72 are separated, and the inner and outer walls of the annular cover 72 are attached to the side walls of the adjacent annular covers 72 and folded in the storage bin 6.

[0032] The lifting cylinder 7 also includes a scissor-type telescopic member 9, which includes a hinge shaft 91, a first connecting rod 92, and a second connecting rod 93; the ends of multiple first connecting rods 92 and the ends of multiple second connecting rods 93 are rotatably connected end to end; the middle parts of adjacent first connecting rods 92 and second connecting rods 93 are rotatably connected through the hinge shaft 91; the hinge shaft 91 located at the bottom is rotatably connected to the storage bin 6 through a bearing, and the remaining hinge shafts 91 are sequentially rotatably connected to the annular cover 72 through bearings; when the scissor-type telescopic member 9 is extended or retracted, multiple hinge shafts 91 move up and down at equal intervals, driving the correspondingly connected annular cover 72 to move up and down at equal intervals, ensuring that the extension and retraction of the lifting cylinder 7 is uniform and smooth.

[0033] In the description of the present invention, the terms "upper", "lower", "front", "back", "left", "right", "top", "bottom", "vertical", "horizontal" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the purpose of describing the present invention rather than requiring the present invention to be constructed or operated in a specific position, and therefore cannot be understood as a limitation on the present invention. The terms "connected" and "connected" in the present invention should be understood in a broad sense, for example, it can be a connection or a detachable connection; it can be a direct connection or an indirect connection through an intermediate component. For those of ordinary skill in the art, the specific meanings of the above terms can be understood according to specific circumstances.

[0034] The above is a preferred embodiment of the present invention, and the description of the specific embodiment is only used to better understand the concept of the present invention. For ordinary technicians in this technical field, several improvements or equivalent substitutions can be made according to the principle of the present invention, and these improvements or equivalent substitutions are also considered to fall within the protection scope of the present invention.

Claims

1. A biological sample extraction mechanism for a liquid nitrogen tank, characterized in that: The invention comprises a reference plate (3), a base (4), a driving assembly (5), a storage bin (6), and a lifting cylinder (7) with an opening at the bottom; the reference plate (3) is horizontally mounted on the top of a tank body (1) of a liquid nitrogen tank, and an extraction port (31) is provided on the reference plate (3) for a sample basket (2) to enter and exit the tank body (1); the base (4) is connected to the reference plate (3) by sliding left and right through the driving assembly (5), a storage bin (6) is arranged on the upper side of the base (4), and a passage penetrating the base (4) is provided at the bottom of the storage bin (6); the driving assembly (5) drives the base (4) to move so that the passage (31) can be extracted. The channel is aligned with the extraction port (31) in upper and lower parts; a transfer port (61) is provided on the side wall of the storage bin (6); the bottom of the lifting cylinder (7) is higher than the transfer port (61) and is connected to the side wall of the storage bin (6), and the top plate (71) of the lifting cylinder (7) is pulled up and down to enter and exit the storage bin (6); a circular hole smaller than the top plane of the sample basket (2) is provided on the top plate (71) of the lifting cylinder (7); a shovel mechanism (8) aligned with the transfer port (61) is installed on the base (4), and the frozen storage box in the sample basket (2) enters and exits the shovel mechanism (8) from the transfer port (61).

2. A biological sample extraction mechanism for a liquid nitrogen tank as claimed in claim 1, characterized in that: The driving assembly (5) comprises a guide rail (51), a driving motor (52), a gear and a rack; the guide rail (51) and the rack are mounted on the reference plate (3) in the left-right direction, and the base (4) is equipped with a pulley matched with the guide rail (51); the output end of the driving motor (52) is equipped with a gear meshing with the rack; and the driving motor (52) is connected to the base (4).

3. A biological sample extraction mechanism for a liquid nitrogen tank as claimed in claim 2, characterized in that: The lifting cylinder (7) is a folding cylinder, and the inner side of the folding cylinder is provided with a heat-insulating material; the lifting cylinder (7) is folded in the storage bin (6).

4. A biological sample extraction mechanism for a liquid nitrogen tank as claimed in claim 2, characterized in that: The lifting cylinder (7) comprises a top plate (71) and a plurality of annular covers (72). The ends of the upper and lower adjacent annular covers (72) are annularly connected to each other, and the inner side surfaces of the annular covers (72) are provided with heat-insulating materials; the top of the annular cover (72) located at the uppermost side is connected to the top plate (71), and the bottom of the annular cover (72) located at the uppermost side is connected to the side wall of the storage bin (6).

5. A biological sample extraction mechanism for a liquid nitrogen tank as claimed in claim 4, characterized in that: The lifting cylinder (7) also includes a scissor-type telescopic member (9), which includes a hinge shaft (91), a first connecting rod (92), and a second connecting rod (93); the ends of multiple first connecting rods (92) and the ends of second connecting rods (93) are rotatably connected end to end; the middle parts of adjacent first connecting rods (92) and second connecting rods (93) are rotatably connected through the hinge shaft (91); the hinge shaft (91) located at the bottom is rotatably connected to the storage bin (6), and the remaining hinge shafts (91) are rotatably connected to the annular cover (72) in sequence.

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