Multiband fluorescent turntable assembly and fluorescent switching device

Abstract

The utility model provides a multiband fluorescent turntable assembly and a fluorescent switching device, the multiband fluorescent turntable assembly comprises: N fluorescent turntables which are coaxially stacked, any one of the fluorescent turntables is provided with at least three through holes for fixing fluorescent modules, and the fluorescent modules located on different fluorescent turntables are arranged in a staggered manner; the driving assembly is used for driving the N fluorescent rotating discs to rotate synchronously and is arranged in the N fluorescent rotating discs; wherein N is an integer and N is greater than or equal to 2. According to the utility model, no gear is needed to transmit power, the precision is high, the service life is long, and the cost can be reduced; the number of the fluorescent modules is increased in a longitudinal extension mode, the size of the fluorescent rotating disc does not need to be increased, the transverse size can be greatly reduced, the occupied space and size are reduced by at least 40% compared with an existing automatic objective lens switching device, and the automatic objective lens switching device has the advantages of being high in manufacturing efficiency, few in parts and high in consistency.

Description

Technical Field

[0001] The utility model relates to the field of multi-band fluorescent turntables, in particular to a multi-band fluorescent turntable component and a fluorescent switching device. Background Art

[0002] Fluorescence technology refers to the ability of a substance to emit visible light after being excited. Fluorescence is based on the release of light of a specific wavelength through the excitation and transition of electrons after a substance absorbs energy. Fluorescence accessories use fluorescence technology to enable the accessories to fluoresce after being exposed to an external light source, thereby achieving visualization or marking of the target. Fluorescence accessories usually need to be designed as an optical system to guide the light from the excitation source to the fluorescent dye and collect the emitted fluorescent light. This optical system generally includes optical components such as lenses, filters, and reflectors to ensure the effective transmission and collection of excitation and fluorescence.

[0003] In the prior art, a Chinese utility model patent with publication number CN214749774U discloses an electric fluorescent turntable, including a turntable, a fluorescent module, a driving mechanism, a fixing device, an origin sensor, a magnetic encoding group, a Hall sensor group and a controller, wherein the driving mechanism includes a stepper motor, a first gear arranged on the output shaft of the stepper motor, a first rotating shaft, a second gear rotatably connected to the first rotating shaft and meshing with the first gear, and a third gear meshing with the second gear, wherein the third gear is fixed to the turntable, and a plurality of working positions are arranged in the circumferential direction inside the turntable, and a fluorescent module is installed at each working position. However, the fluorescent turntable still has the following problems:

[0004] 1. The gear meshing transmission positioning accuracy is poor and the service life is short;

[0005] 2. The assembly process is complicated, with many parts and a long debugging cycle;

[0006] 3. The wavelength bands are relatively small. If a fluorescent module is required, the size of the turntable will increase.

[0007] 4. There is a lot of dust, the gears are easy to wear, and there is a hidden danger of affecting the optical path. Utility Model Content

[0008] The utility model aims to provide a multi-band fluorescent turntable assembly and a fluorescent switching device, which do not need to use gears to transmit power and have the characteristics of high precision, long life and smaller space occupation.

[0009] In order to achieve the above-mentioned utility model object, the utility model provides a multi-band fluorescent turntable assembly, comprising:

[0010] N coaxially stacked fluorescent rotating disks, any of which is provided with at least three through holes for fixing fluorescent modules, and the fluorescent modules on different fluorescent rotating disks are staggered;

[0011] A driving assembly for driving the N fluorescent rotating disks to rotate synchronously, which is arranged inside the N fluorescent rotating disks;

[0012] Wherein, N is an integer and N≥2.

[0013] According to a technical solution of the present utility model, any of the fluorescent modules is fixedly disposed on the lower surface of the corresponding fluorescent rotating disk.

[0014] According to a technical solution of the utility model, the driving assembly includes a harmonic reducer and a stepping motor.

[0015] According to a technical solution of the utility model, the plurality of fluorescent modules located on the N fluorescent rotating disks are arranged in an equidistant and staggered manner.

[0016] According to a technical solution of the utility model, the fluorescent module and the fluorescent turntable are fixed by magnetic attraction or bolts.

[0017] According to a technical solution of the present utility model, the fluorescent modules of the same fluorescent rotating disk are of the same type.

[0018] According to one aspect of the utility model, a fluorescence switching device is provided, comprising:

[0019] Support platform;

[0020] A rotatable light source turntable is horizontally arranged on the supporting platform, a plurality of light sources are fixed on the light source turntable through light source fixing holes, and the emission direction of any of the light sources is perpendicular to the supporting platform;

[0021] As the multi-band fluorescent rotating disk assembly described in any one of the above technical solutions, any one of the fluorescent rotating disks is arranged horizontally with the supporting platform;

[0022] The optical path diameters are the same as the number of the fluorescent rotating disks and are arranged one-to-one;

[0023] A vertically movable reflector located below the light source turntable;

[0024] An optical path camera is arranged above the multi-band fluorescent turntable assembly.

[0025] According to a technical solution of the utility model, the light source turntable is arranged on the supporting platform through supporting columns.

[0026] According to a technical solution of the utility model, the reflector is arranged on the side of the supporting column.

[0027] According to a technical solution of the utility model, the optical path tube diameter is fixed on the supporting platform through a tube diameter fixing piece.

[0028] According to a technical solution of the utility model, the reflector is provided with a position switching device for switching the reflector between a plurality of the optical path diameters.

[0029] According to a technical solution of the utility model, the light source turntable is in a "cross" shape, and the four light source fixing holes are arranged at the four end points of the "cross".

[0030] According to a technical solution of the utility model, a position sensor is arranged directly below one of the light sources, and the position sensor is fixed on the supporting column.

[0031] According to one concept of the utility model, a multi-band fluorescence turntable assembly is proposed. By assembling N fluorescence turntables in a coaxial staggered manner, multiple fluorescence modules arranged on the N fluorescence turntables can form a path with the light source, the optical path tube diameter, and the optical path camera, so that a multi-band fluorescence microscope allows the user to switch between different excitation wavelengths to observe structures marked by different fluorescent dyes in the sample. A multi-band fluorescence turntable assembly can be configured with at least 6 fluorescence modules and is compatible with more bands. It uses a drive assembly placed on the inner side of the fluorescence turntable for electronic control, does not need to use gears to transmit power, has the characteristics of high precision and high life, and can also reduce costs.

[0032] Furthermore, the multi-band fluorescent turntable assembly of the present application increases the number of fluorescent modules by longitudinal extension without increasing the size of the fluorescent turntable, which can greatly reduce the lateral size. The space and volume occupied are reduced by at least 40% compared to the existing automatic objective lens switching device, and has the characteristics of high manufacturing efficiency, fewer parts and high consistency.

[0033] According to another concept of the utility model, a fluorescence switching device is proposed, which realizes switching by being equipped with a rotatable light source turntable, a reflector that can be moved up and down, and a multi-band fluorescence turntable assembly. It has the characteristics of smoothness, no jamming, and low noise, and the switching of each component is softer. It is compatible with the scanning application scenarios of the microscope and can achieve compatibility between bright field and fluorescence. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0035] Figure 1 A three-dimensional diagram schematically shows a fluorescence switching device equipped with a multi-band fluorescence turntable assembly according to an embodiment of the utility model.

[0036] Reference numerals:

[0037] 1. Fluorescent turntable; 2. Through hole; 3. Fluorescent module; 4. Support platform; 5. Light source turntable; 6. Optical path tube diameter; 7. Reflector; 8. Optical path camera; 9. Support column; 10. Tube diameter fixing piece; 11. Position switching device; 12. Position sensor; 13. Gantry. DETAILED DESCRIPTION

[0038] The description of the embodiments of this specification should be combined with the corresponding drawings, which should be considered as part of the complete specification. In the drawings, the shape or thickness of the embodiments may be enlarged and indicated for simplification or convenience. Furthermore, the parts of each structure in the drawings will be described separately. It is worth noting that the elements not shown in the drawings or not described in words are in a form known to ordinary technicians in the relevant technical field.

[0039] The description of the embodiments herein and any reference to directions and orientations are only for the convenience of description and are not to be construed as any limitation on the scope of protection of the present invention. The following description of the preferred embodiments may involve combinations of features, which may exist independently or in combination, and the present invention is not particularly limited to the preferred embodiments. The scope of the present invention is defined by the claims.

[0040] When describing the embodiments of the present invention, the orientation or positional relationship expressed by the terms "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside" and "outside" are based on the orientation or positional relationship shown in the relevant drawings. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operate in a specific orientation. Therefore, the above terms cannot be understood as limiting the present invention.

[0041] The present invention will be described in detail below in conjunction with the accompanying drawings and specific implementation methods. The implementation methods cannot be described one by one here, but the implementation methods of the present invention are not therefore limited to the following implementation methods.

[0042] like Figure 1 As shown, according to one embodiment of the utility model, the utility model provides a multi-band fluorescent turntable assembly, including:

[0043] N coaxially stacked fluorescent rotating disks 1, any fluorescent rotating disk 1 is provided with at least three through holes 2 for fixing fluorescent modules 3, and the fluorescent modules 3 located on different fluorescent rotating disks 1 are staggered;

[0044] A driving assembly (not shown in the figure, and it can be arranged inside the fluorescent rotating disk 1) for driving the N fluorescent rotating disks 1 to rotate synchronously is arranged inside the N fluorescent rotating disks 1;

[0045] Wherein, N is an integer and N≥2.

[0046] In this embodiment, N fluorescent turntables 1 are assembled in a coaxial staggered manner, so that the multiple fluorescent modules 3 arranged on the N fluorescent turntables 1 can form a path with the light source, the optical path tube 6, and the optical path camera 8, so that a multi-band fluorescence microscope allows the user to switch between different excitation wavelengths to observe structures marked by different fluorescent dyes in the sample. A multi-band fluorescent turntable assembly can be equipped with at least 6 fluorescent modules 3, which is compatible with more bands. It uses a driving assembly placed on the inner side of the fluorescent turntable 1 for electronic control, and does not need to use gears to transmit power. It has the characteristics of high precision and long life, and can also reduce costs.

[0047] Furthermore, the multi-band fluorescent turntable assembly of the present application increases the number of fluorescent modules 3 by longitudinal extension, without increasing the size of the fluorescent turntable 1, and can greatly reduce the lateral size. The space and volume occupied are reduced by at least 40% compared to the existing automatic objective lens switching device, and it has the characteristics of high manufacturing efficiency, few parts and high consistency.

[0048] The staggered arrangement means that all the fluorescent modules 3 are regarded as being on the same plane, and two adjacent fluorescent modules 3 are respectively located on two different fluorescent rotating disks 1 .

[0049] It is understandable that the fluorescent rotating disk 1 should also be provided with light-through holes, and the positions of the light-through holes are located at positions corresponding to the fluorescent modules 3 of other layers.

[0050] In addition, a plurality of fluorescent rotating disks are stacked and arranged at equal intervals.

[0051] In some embodiments of the present invention, any fluorescent module 3 is fixedly disposed on the lower surface of the corresponding fluorescent rotating disk 1 .

[0052] In some embodiments of the present invention, the driving assembly includes a harmonic reducer and a stepper motor.

[0053] In this embodiment, N fluorescent turntables 1 are synchronously fixed on the stepper motor through fixing parts. After installation, the upper and lower turntables are calibrated to ensure concentricity, which can ensure the position accuracy of the fluorescent module 3. At the same time, the harmonic reducer is used in conjunction with the stepper motor to increase the reduction ratio, improve the accuracy, and increase the torque, thereby supporting the rotation of fluorescent modules 3 of more bands.

[0054] The fluorescent rotating disk 1 is arranged in an evenly spaced staggered manner, and the stepping motor can be arranged to rotate at an evenly spaced interval.

[0055] For example, two fluorescent turntables 1 are used to form a multi-band fluorescent turntable assembly, and each fluorescent turntable 1 is configured with three fluorescent modules 3. Then the multi-band fluorescent turntable assembly has a total of six fluorescent modules 3. The six fluorescent modules 3 are arranged in an equidistant and staggered manner, and are regarded as being on the same plane. Two adjacent fluorescent modules 3 are respectively located on two fluorescent turntables 1, and the angle between two adjacent fluorescent modules 3 is 60°.

[0056] It is understandable that a non-equidistant staggered arrangement may also be adopted.

[0057] In some embodiments of the utility model, the fluorescence module 3 is fixed to the fluorescence turntable 1 by magnetic attraction or bolts, which is beneficial to improve stability. Typically, the fluorescence module 3 includes an upper module, a dichroic mirror and a lower module. In addition to the dichroic mirror, the fluorescence module 3 can be used to fix the excitation filter and the emission filter. The second lower suction piece is located on the bottom surface of the lower module, and the second upper suction piece is located on the side of the upper module. The dichroic mirror is clamped between the upper module and the lower module, and the upper module and the lower module are fixed together by snaps, bolts or glue, wherein the dichroic mirror can be embedded between the upper module and the lower module, or can be fixed between the upper module and the lower module by glue.

[0058] In some embodiments of the utility model, the fluorescent modules 3 of the same fluorescent turntable 1 are of the same type. For example, a double-layer multi-band fluorescent turntable assembly is used, with the upper layer being long wave and the lower layer being short wave. At the same time, the lower layer can be a commonly used band and the upper layer can be an uncommon band, which has the advantage of easy disassembly.

[0059] According to one aspect of the utility model, a fluorescence switching device is provided, comprising:

[0060] Support platform 4;

[0061] A rotatable light source turntable 5 is horizontally arranged on the supporting platform 4. A plurality of light sources are fixed on the light source turntable 5 through light source fixing holes. The emission direction of any light source is perpendicular to the supporting platform 4.

[0062] As in any one of the multi-band fluorescent turntable components of the above technical solutions, any fluorescent turntable 1 is arranged horizontally with the supporting platform 4;

[0063] The optical path diameters 6 are the same in number as the fluorescent rotating disks 1 and are arranged one-to-one;

[0064] A reflector 7 located below the light source turntable 5 and capable of vertical movement, for example, when two fluorescent turntables 1 are stacked up and down, two optical path diameters 6 are correspondingly arranged, and when a fluorescent module 3 on the upper fluorescent turntable 1 is used, the reflector 7 is moved upward to the corresponding position of the upper fluorescent turntable 1;

[0065] An optical path camera 8 is arranged above the multi-band fluorescent turntable assembly.

[0066] In this embodiment, the fluorescent switching device is equipped with a supporting platform 4, which can provide a more stable supporting force and ensure stability, thereby ensuring the accuracy of light transmission; the rotatable light source turntable 5 is horizontally arranged on the supporting platform 4, and the reflector 7 can move vertically up and down, corresponding to the optical path tube diameter 6 and the fluorescent turntable 1 at each position, and the light source forms a complete optical path through the reflector 7, the optical path tube diameter 6, the fluorescent module 3 and the optical path camera 8.

[0067] The switching is achieved by using a rotatable light source turntable 5, a reflector 7 that can be moved up and down, and a multi-band fluorescent turntable assembly. It has the characteristics of smoothness, no jamming, and low noise. The switching of each component is softer, compatible with the scanning application scenarios of the microscope, and can achieve compatibility with bright field and fluorescence.

[0068] In addition, the multiple light sources fixed on the light source turntable 5 are compatible with multi-color LED and fiber optic lighting.

[0069] In some embodiments of the present invention, the light source turntable 5 is disposed on the supporting platform 4 via supporting columns 9 to ensure the height of the light source and improve stability.

[0070] A gantry 13 is disposed on the light source turntable 5 , and a wire arrangement hole is provided at the center of the gantry 13 to prevent the connecting wires from blocking the light source.

[0071] In some embodiments of the present invention, the reflector 7 is disposed on the side of the supporting column 9 .

[0072] In some embodiments of the present invention, the optical path tube diameter 6 is fixed on the supporting platform 4 via a tube diameter fixing member 10 .

[0073] In some embodiments of the utility model, the reflector 7 is provided with a position switching device 11 for switching the reflector 7 between a plurality of optical path diameters 6, and the position of the reflector 7 is adjusted according to the positions of different fluorescent modules 3. For example, the up and down movement of the reflector 7 can be controlled by a single screw rod.

[0074] In some embodiments of the utility model, the light source turntable 5 is in a "cross" shape, and four light source fixing holes are arranged at the four end points of the "cross", so that the light source can protrude from the supporting column, thereby forming an effective light path with the reflector 7, the light path tube diameter 6, etc.

[0075] In some embodiments of the utility model, a position sensor 12 is arranged directly below one of the light sources. The position sensor 12 is fixed on the supporting column 9. The initial position of the light source is determined by the position sensor 12, so as to quickly distinguish the position of the light source, the current light source type, etc.

[0076] The switchable device of the present invention can be tested and used by the following method after being assembled: the light source is emitted through the light source turntable 5, the reflector 7 stops at the required position, the light is refracted 90°, and when the light is irradiated to the fluorescent module 3, part of the required band is intercepted for fluorescent imaging detection.

[0077] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A multi-band fluorescent turntable assembly, characterized in that: include: N coaxially stacked fluorescent rotating disks (1), any one of the fluorescent rotating disks (1) being provided with at least three through holes (2) for fixing the fluorescent modules (3), and the fluorescent modules (3) located on different fluorescent rotating disks (1) being arranged in staggered positions; A driving component for driving the N fluorescent rotating disks (1) to rotate synchronously, arranged inside the N fluorescent rotating disks (1); Wherein, N is an integer and N≥2.

2. The multi-band fluorescent rotating disk assembly according to claim 1, characterized in that: Any of the fluorescent modules (3) is fixedly arranged on the lower surface of the corresponding fluorescent rotating disk (1).

3. The multi-band fluorescent rotating disk assembly according to claim 1, characterized in that: The driving assembly includes a harmonic reducer and a stepping motor.

4. The multi-band fluorescent rotating disk assembly according to claim 1, characterized in that: The plurality of fluorescent modules (3) located on the N fluorescent rotating disks (1) are arranged in an equidistant and staggered manner.

5. The multi-band fluorescent rotating disk assembly according to claim 1, characterized in that: The fluorescent module (3) and the fluorescent rotating disk (1) are fixed by magnetic attraction or bolts.

6. The multi-band fluorescent rotating disk assembly according to claim 1, characterized in that: The fluorescent modules (3) of the same fluorescent rotating disk (1) are of the same type.

7. A fluorescence switching device, characterized in that: include: Support platform (4); A rotatable light source turntable (5) is horizontally arranged on the supporting platform (4); a plurality of light sources are fixed on the light source turntable (5) through light source fixing holes, and the emission direction of any of the light sources is perpendicular to the supporting platform (4); The multi-band fluorescent rotating disk assembly according to any one of claims 1 to 6, wherein any one of the fluorescent rotating disks (1) and the supporting platform (4) are arranged horizontally; The optical path tube diameters (6) are the same in number as the fluorescent rotating disks (1) and are arranged in one-to-one correspondence; A reflector (7) located below the light source rotating disk (5) and capable of vertical movement; An optical path camera (8) is arranged above the multi-band fluorescent turntable assembly.

8. The fluorescence switching device according to claim 7, characterized in that: The light source rotating disk (5) is arranged on the supporting platform (4) via a supporting column (9).

9. The fluorescence switching device according to claim 8, characterized in that: The reflector (7) is arranged on the side of the supporting column (9).

10. The fluorescence switching device according to claim 7, characterized in that: The optical path tube diameter (6) is fixed on the supporting platform (4) via a tube diameter fixing piece (10).

11. The fluorescence switching device according to claim 7, characterized in that: The reflector (7) is provided with a position switching device (11) for switching the reflector (7) between a plurality of light path diameters (6).

12. The fluorescence switching device according to claim 7, characterized in that: The light source rotating disk (5) is in the shape of a cross, and the four light source fixing holes are arranged at the four end points of the cross.

13. The fluorescence switching device according to claim 9, characterized in that: A position sensor (12) is arranged directly below one of the light sources, and the position sensor (12) is fixed on the supporting column (9).

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