Chromatographic column mounting device with temperature and illumination dual regulation and control functions

Abstract

The utility model relates to a chromatographic column mounting device with a temperature and illumination dual regulation and control function. The chromatographic column mounting device comprises a mounting seat assembly; the constant-temperature assembly is arranged on the mounting seat assembly, the constant-temperature assembly is provided with a chromatographic column mounting part and a light-transmitting part, and the chromatographic column is at least partially mounted in the constant-temperature assembly through the chromatographic column mounting part; and the light-emitting assembly is arranged on the mounting seat assembly and is arranged corresponding to the light-transmitting part of the constant-temperature assembly. According to the technical scheme, integration and diversified regulation and control of the temperature and illumination system of the chromatographic column are achieved, and the problems that single control wastes time and labor and is not high in precision are effectively solved, and the influence of the illumination heating effect on the chromatographic separation degree is effectively solved.

Description

Technical Field

[0001] The present application relates to the technical field of chromatographic column auxiliary devices, and in particular to a chromatographic column installation device with dual temperature and light control functions. Background Art

[0002] Capillary chromatography has been used to analyze various complex mixtures, including atmospheric and environmental pollutants, biological samples, food, mineral fuels, cosmic matter, and some inorganic and metal organic substances.

[0003] The detection of chromatographic columns has strict temperature conditions, namely the upper and lower temperature limits. If the detection of the chromatographic column is not within this temperature range, the chromatographic column cannot perform its normal function.

[0004] When the temperature of some chromatographic columns in the prior art is not within the normal temperature range during detection, processing is required, such as waiting for the temperature to reach the normal temperature range before detection, which not only delays time but also reduces the measurement accuracy. Utility Model Content

[0005] The present application provides a chromatography column installation device with dual temperature and light control functions to solve the problem of single control being time-consuming, labor-intensive and low-precision in the prior art.

[0006] A chromatographic column installation device with dual temperature and light control functions provided by the present application includes: a mounting seat assembly; a constant temperature assembly, which is arranged on the mounting seat assembly, the constant temperature assembly has a chromatographic column mounting portion and a light-transmitting portion, and the chromatographic column is at least partially installed in the constant temperature assembly through the chromatographic column mounting portion; a light-emitting assembly, which is arranged on the mounting seat assembly and is arranged corresponding to the light-transmitting portion of the constant temperature assembly.

[0007] Furthermore, the thermostatic assembly includes a thermostatic tube structure and a sealing structure. The thermostatic tube structure has two through holes. The chromatographic column is inserted into the two through holes. The sealing structure is sealed and installed in cooperation with the two through holes and the chromatographic column.

[0008] Furthermore, the constant temperature pipe structure includes an inlet pipe section, a main pipe section and an outlet pipe section. The two ends of the main pipe section are sealed and connected to the inlet pipe section and the outlet pipe section respectively. The two through holes are respectively located on the inlet pipe section and the outlet pipe section and are arranged corresponding to the main pipe section.

[0009] Furthermore, the light emitting assembly includes a light emitting structure, and the light emitting structure is arranged on the circumferential outer side of the main pipe section.

[0010] Furthermore, the light emitting structure has light emitters with multiple wavelengths.

[0011] Furthermore, the light-emitting bodies of multiple wavelengths include two types, and the light-emitting bodies of the two wavelengths are arranged at intervals.

[0012] Furthermore, the mounting seat assembly includes a mounting seat structure and a heat dissipation structure, and the heat dissipation structure is arranged on the mounting seat structure and is arranged corresponding to the light-emitting assembly.

[0013] Furthermore, the heat dissipation structure includes a plurality of heat dissipation fins, and the heat dissipation fins are arranged on a side of the mounting seat structure away from the light-emitting component.

[0014] Furthermore, the chromatographic column installation device with dual temperature and light control functions also includes a control component and a first temperature detection component. The first temperature detection component is arranged on the constant temperature component and is electrically connected to the control component.

[0015] Furthermore, the chromatographic column installation device with dual temperature and light control functions also includes a second temperature detection component, which is arranged on the mounting seat component and is arranged corresponding to the light-emitting component.

[0016] By applying the technical solution of the present application, when in use, the chromatographic column is installed on the thermostatic assembly, so that the chromatographic column can be ensured to be in the normal temperature range for detection, that is, there is no need to wait for the temperature of the chromatographic column to return to the normal temperature range. The light-emitting component is installed on the mounting seat assembly, and such a structure makes the illumination controllable and improves the detection accuracy. The technical solution of the present application effectively solves the problem of single control being time-consuming, labor-intensive and low-precision in the prior art. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the present application and, together with the description, serve to explain the principles of the present application.

[0018] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, for ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative labor.

[0019] Figure 1 A schematic diagram of the structure of a chromatographic column installation device with dual temperature and light control functions according to an embodiment of the present application is shown;

[0020] Figure 2 Shows Figure 1 A schematic diagram of a chromatographic column installation device with dual temperature and light control functions and a chromatographic column installation structure;

[0021] Figure 3 Shows Figure 1 Schematic diagram of the structure of the light-emitting component of the chromatographic column installation device with dual temperature and light control functions.

[0022] The above drawings include the following reference numerals:

[0023] 10. Mounting seat assembly; 11. Mounting seat structure; 12. Heat dissipation structure; 20. Constant temperature assembly; 21. Constant temperature pipe structure; 211. Liquid inlet pipe section; 212. Main pipe section; 213. Liquid outlet pipe section; 22. Sealing structure; 30. Light-emitting assembly; 31. Light-emitting body; 100. Chromatographic column. DETAILED DESCRIPTION

[0024] It should be noted that, in the absence of conflict, the embodiments and features in the embodiments of the present application can be combined with each other. The present application will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.

[0025] It should be noted that the following detailed descriptions are illustrative and are intended to provide further explanation of the present application. Unless otherwise specified, all technical and scientific terms used herein have the same meanings as those commonly understood by those skilled in the art to which the present application belongs.

[0026] For ease of description, spatially relative terms such as "above", "above", "on the upper surface of", "above", etc. may be used herein to describe the spatial positional relationship between a device or feature and other devices or features as shown in the figure. It should be understood that spatially relative terms are intended to include different orientations of the device in use or operation in addition to the orientation described in the figure. For example, if the device in the accompanying drawings is inverted, the device described as "above other devices or structures" or "above other devices or structures" will be positioned as "below other devices or structures" or "below other devices or structures". Thus, the exemplary term "above" may include both "above" and "below". The device may also be positioned in other different ways, rotated 90 degrees or in other orientations, and the spatially relative descriptions used herein are interpreted accordingly.

[0027] like Figures 1 to 3 As shown, the chromatographic column installation device with dual temperature and light control functions of this embodiment includes: a mounting seat assembly 10, a constant temperature assembly 20 and a light emitting assembly 30. The constant temperature assembly 20 is arranged on the mounting seat assembly 10, and the constant temperature assembly 20 has a chromatographic column mounting portion and a light-transmitting portion, and the chromatographic column is at least partially installed in the constant temperature assembly 20 through the chromatographic column mounting portion. The light emitting assembly 30 is arranged on the mounting seat assembly 10 and is arranged corresponding to the light-transmitting portion of the constant temperature assembly 20.

[0028] By applying the technical solution of the present application, when in use, the chromatographic column 100 is installed on the constant temperature component 20, so that the chromatographic column 100 can be ensured to be in a normal temperature range for detection, that is, there is no need to wait for the temperature of the chromatographic column 100 to return to the normal temperature range. The light-emitting component 30 is installed on the mounting seat component 10, and such a structure makes the illumination controllable and improves the detection accuracy. The technical solution of this embodiment effectively solves the problem of single control being time-consuming, labor-intensive and low-precision in the prior art.

[0029] It should be noted that the light emitting assembly 30 is detachably connected to the mounting base assembly 10, for example, by fasteners or bonding, so that different light emitting assemblies 30 can be replaced. The two light emitters 31 of this embodiment are a blue light emitting diode (wavelength of 460nm) and an ultraviolet light emitting diode (wavelength of 365nm).

[0030] like Figure 1 and Figure 2 As shown, in the technical solution of this embodiment, the thermostatic assembly 20 includes a thermostatic tube structure 21 and a sealing structure 22. The thermostatic tube structure 21 has two through holes, and the chromatographic column is inserted into the two through holes. The sealing structure 22 is sealed and installed in the two through holes and cooperates with the chromatographic column. The above structure is compact and easy to disassemble and assemble.

[0031] like Figure 1 and Figure 2 As shown, in the technical solution of this embodiment, the thermostatic tube structure 21 includes a liquid inlet tube section 211, a main tube section 212 and a liquid outlet tube section 213, and the two ends of the main tube section 212 are respectively sealed and connected to the liquid inlet tube section 211 and the liquid outlet tube section 213, and the two vias are respectively located on the liquid inlet tube section 211 and the liquid outlet tube section 213, and are arranged corresponding to the main tube section 212. The above structure makes the arrangement of the thermostatic tube structure 21 more flexible, and the coordination effect of the thermostatic component 20 and the light-emitting component 30 is better.

[0032] It should be noted that the inlet pipe section 211 and the outlet pipe section 213 are both L-shaped, the main pipe section 212 is arranged horizontally, the inlet of the inlet pipe section 211 is located at the upper part of the mounting seat assembly 10, and the outlet of the inlet pipe section 211 is located inside the mounting seat assembly 10. The sealing structure 22 includes two nuts and two sealing gaskets, the external threads of the nuts are matched and connected with the internal threads of the through holes, the through holes are stepped holes with large outside and small inside, and the sealing gasket is located between the nuts and the steps. The nuts and the sealing gaskets are both provided with sealing holes matched with the chromatographic column. There is a sealing ring between the inner wall of the inlet pipe section 211 and the outer wall of the main pipe section 212, and there is a sealing ring between the inner wall of the outlet pipe section 213 and the outer wall of the main pipe section 212.

[0033] like Figure 1 and Figure 2As shown, in the technical solution of this embodiment, the light emitting assembly 30 includes a light emitting structure, and the light emitting structure is arranged on the circumferential outer side of the main tube section 212. In this way, the light emitting structure can be transmitted to the chromatographic column 100 through the main tube section 212.

[0034] like Figure 3 As shown, in the technical solution of this embodiment, the light emitting structure has light emitters 31 of multiple wavelengths. In this way, a correspondence between light of different wavelengths and the chromatographic column can be made. It should be noted that the light emitters 31 of multiple wavelengths are arranged in an array.

[0035] like Figure 3 As shown, in the technical solution of this embodiment, the multiple wavelength illuminators 31 include two types, and the two wavelength illuminators 31 are arranged at intervals. In this way, the regularity of the test is better. Of course, as other implementations, the light emitting assembly 30 can be disassembled, that is, other types of light emitting assemblies 30 can be replaced as needed.

[0036] like Figure 1 and Figure 2 As shown, in the technical solution of this embodiment, the mounting seat assembly 10 includes a mounting seat structure 11 and a heat dissipation structure 12, and the heat dissipation structure 12 is arranged on the mounting seat structure 11 and is arranged corresponding to the light emitting assembly 30. The arrangement of the heat dissipation structure 12 makes the temperature of the light emitting assembly 30 more constant, thereby improving the test accuracy.

[0037] like Figure 1 and Figure 2 As shown, in the technical solution of this embodiment, the heat dissipation structure 12 includes a plurality of heat dissipation fins, and the heat dissipation fins are arranged on the side of the mounting seat structure 11 away from the light-emitting component 30. The above structure is compact and easy to process. It should be noted that a fan can also be placed next to the fins to force heat dissipation. As another embodiment, the heat dissipation structure 12 can be a jacket heat exchange structure, and the heat of the light-emitting body 31 is conducted away by a fluid such as heat-conducting oil or water in the jacket heat exchange structure, so that the light-emitting body 31 maintains a certain constant temperature.

[0038] In the technical scheme of the present embodiment (not shown in the figure), the chromatographic column installation device with dual control functions of temperature and light also includes a control component and a first temperature detection component, and the first temperature detection component is arranged on the thermostatic component 20 and is electrically connected to the control component. In this way, the temperature control effect of the thermostatic component 20 of the chromatographic column installation device with dual control functions of temperature and light can be better. The thermostatic tube structure 21 is connected to the fluid pool and the pump outside, and the first temperature detection component is electrically connected to the pump. When the first temperature detection component detects a temperature greater than a preset value, the pump starts or increases the flow rate, and when the first temperature detection component detects a temperature less than a preset value, the pump starts or increases the flow rate, and when the first temperature detection component detects a temperature in the middle, the pump flow rate slows down, until the temperature of the first temperature detection component is constant.

[0039] In the technical solution of this embodiment (not shown in the figure), the chromatographic column installation device with dual temperature and light control functions also includes a second temperature detection component, which is arranged on the mounting seat component 10 and is arranged corresponding to the light emitting component 30. The second temperature detection component can detect the relationship between the temperature of the light emitting body 31 and the chromatographic column 100 on the one hand, and can also keep the light emitting body 31 at a constant temperature on the other hand. For example, when the second temperature detection component detects that the temperature of the light emitting body 31 is about to exceed the normal range, external forced heat exchange is performed.

[0040] From the above, it can be seen that the technical solution of the present application is a column temperature box with light control function for a capillary photosensitive chromatographic column (a chromatographic column installation device with dual temperature and light control functions), which includes two parts: a light box and a column temperature control body.

[0041] The illumination box is used to provide programmable illumination control for a capillary photosensitive chromatographic column. The illumination box is mainly composed of an illumination box shell (mounting seat structure 11) made of a selected aluminum alloy and having a shape close to a rectangular parallelepiped; small holes (removal holes) are reserved on both sides of the illumination box shell to put in or take out the capillary photosensitive chromatographic column 100; two openings for circulating water joints (liquid inlet pipe section 211 and liquid outlet pipe section 213) are reserved on the top of the illumination box shell so that the column temperature control body can be connected to external circulating water; lamp heat sinks (heat dissipation structure 12) are arranged on the outside of the top, bottom, front and rear sides of the illumination box shell to dissipate heat for the lamp array; and lamp arrays are arranged on the inside of the top, bottom, front and rear sides of the illumination box shell.

[0042] The lamp array consists of alternating blue light emitting diodes (wavelength 460nm) and ultraviolet light emitting diodes (wavelength 365nm).

[0043] The temperature control body (constant temperature component 20) is used to provide a stable column temperature for the capillary photosensitive chromatographic column. The temperature control body is arranged inside the light irradiation box housing; the column temperature control body is composed of two condensation joints (liquid inlet pipe section 211 and liquid outlet pipe section 213) and a quartz tube (main pipe section 212); a selected rubber quartz tube sealing ring and a quartz tube sealing gland are arranged in the condensation joint; the rubber quartz tube sealing ring and the quartz tube sealing gland are plugged into the end of the quartz tube; the quartz tube sealing ring is squeezed by adjusting the quartz tube sealing gland to produce deformation, thereby realizing the sealed connection between the condensation joint and the quartz tube.

[0044] The outer side of the condensation joint is cylindrical, and the top surface of the cylinder is provided with concentric through holes and concentric bolt internal thread holes; the internal thread holes are provided with selected silicone capillary sealing pads and selected stainless steel hollow capillary sealing bolts. The capillary sealing bolts are adjusted to squeeze the capillary sealing pads to produce deformation and squeeze the capillary photosensitive chromatographic column and the internal thread holes of the condensation joint, thereby achieving a sealed connection between the condensation joint and the photosensitive chromatographic column.

[0045] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprise" and / or "include" are used in this specification, it indicates the presence of features, steps, operations, devices, components and / or combinations thereof.

[0046] It should be noted that the terms "first", "second", etc. in the specification and claims of the present application and the above-mentioned drawings are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequence. It should be understood that the data used in this way can be interchangeable where appropriate, so that the embodiments of the present application described herein can be implemented in an order other than those illustrated or described herein, for example. In addition, the terms "including" and "having" and any of their variations are intended to cover non-exclusive inclusions, for example, a process, method, system, product or device that includes a series of steps or units is not necessarily limited to those steps or units that are clearly listed, but may include other steps or units that are not clearly listed or inherent to these processes, methods, products or devices.

[0047] The above are only preferred embodiments of the present application and are not intended to limit the present application. For those skilled in the art, the present application may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A chromatographic column installation device with dual temperature and light control functions, characterized in that: include: Mounting seat assembly (10); A thermostatic component (20), the thermostatic component (20) being arranged on the mounting seat component (10), the thermostatic component (20) comprising a chromatographic column mounting portion and a light-transmitting portion, the chromatographic column being at least partially mounted in the thermostatic component (20) via the chromatographic column mounting portion; A light emitting component (30) is arranged on the mounting seat component (10) and is arranged corresponding to the light-transmitting portion of the thermostatic component (20).

2. The chromatographic column installation device with dual temperature and light control functions according to claim 1, characterized in that: The thermostatic assembly (20) comprises a thermostatic tube structure (21) and a sealing structure (22), wherein the thermostatic tube structure (21) has two through holes, the chromatographic column is inserted into the two through holes, and the sealing structure (22) is sealingly installed in the two through holes and cooperates with the chromatographic column.

3. The chromatographic column installation device with dual temperature and light control functions according to claim 2, characterized in that: The constant temperature pipe structure (21) comprises a liquid inlet pipe section (211), a main pipe section (212) and a liquid outlet pipe section (213); two ends of the main pipe section (212) are respectively sealed and connected to the liquid inlet pipe section (211) and the liquid outlet pipe section (213); the two through holes are respectively located on the liquid inlet pipe section (211) and the liquid outlet pipe section (213), and are arranged corresponding to the main pipe section (212).

4. The chromatographic column installation device with dual temperature and light control functions according to claim 3, characterized in that: The light emitting assembly (30) comprises a light emitting structure, and the light emitting structure is arranged on the circumferential outer side of the main pipe section (212).

5. The chromatographic column installation device with dual temperature and light control functions according to claim 4, characterized in that: The light-emitting structure has light-emitting bodies (31) with multiple wavelengths.

6. The chromatographic column installation device with dual temperature and light control functions according to claim 5, characterized in that: The luminous bodies (31) of multiple wavelengths include two types, and the luminous bodies (31) of the two wavelengths are arranged at intervals.

7. The chromatographic column installation device with dual temperature and light control functions according to any one of claims 3 to 6, characterized in that: The mounting seat assembly (10) comprises a mounting seat structure (11) and a heat dissipation structure (12); the heat dissipation structure (12) is arranged on the mounting seat structure (11) and is arranged corresponding to the light-emitting assembly (30).

8. The chromatographic column installation device with dual temperature and light control functions according to claim 7, characterized in that: The heat dissipation structure (12) comprises a plurality of heat dissipation fins, and the heat dissipation fins are arranged on a side of the mounting seat structure (11) away from the light-emitting component (30).

9. The chromatographic column installation device with dual temperature and light control functions according to any one of claims 1 to 6, characterized in that: The chromatographic column installation device with dual temperature and light control functions also includes a control component and a first temperature detection component, wherein the first temperature detection component is arranged on the constant temperature component (20) and is electrically connected to the control component.

10. The chromatographic column installation device with dual temperature and light control functions according to claim 7, characterized in that: The chromatographic column installation device with dual temperature and light control functions further comprises a second temperature detection component, which is arranged on the mounting seat component (10) and is arranged corresponding to the light emitting component (30).

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