Granulator for pharmaceutical production

By introducing a spiral blade conveyor, hot air drying, and cold air cooling design into the granulator, the problems of excessive temperature and contamination in the granulator are solved, ensuring drug quality and operational safety, and achieving stability in drug production and environmental protection.

CN223774791UActive Publication Date: 2026-01-09JILIN YIPU BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202520194694.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-02-08
Publication Date
2026-01-09
Estimated Expiration
2035-02-08

AI Technical Summary

Technical Problem

Existing granulation machines suffer from problems such as excessively high temperatures during production, leading to particle sticking and deformation, which affects the stability and quality of drugs. At the same time, raw materials are easily contaminated, and there are insufficient safety and environmental protection considerations for operators.

Method used

A granulator comprising a granulation chamber, a drying chamber, and a cold air chamber was designed. The material is conveyed by a spiral blade, dried by a hot air blower, and cooled by a cold air blower. Combined with scraper cutting and conveyor belt transport, the material is uniformly conveyed, dried, and cooled, ensuring the quality and safety of the medicine.

Benefits of technology

It achieves stable delivery and uniform drying and cooling of pharmaceutical raw materials, avoids particle adhesion and deformation, improves drug quality and operational safety, and reduces the risk of environmental pollution.

✦ Generated by Eureka AI based on patent content.

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    Figure CN223774791U_ABST
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Abstract

The utility model discloses a granulator for medicine production, which comprises a granulating box and a drying box, the top of the granulating box is connected with a conveying cylinder through a pipeline, one end of the conveying cylinder is fixedly connected with a first motor, one side of the conveying cylinder is connected with a storage bin through a pipeline, the four corners of the bottom of the storage bin are fixedly connected with support columns, and the support columns are fixedly connected with the drying box. A frame is fixedly connected to the outer surface of the granulating box, a first connecting pipe is fixedly connected to the bottom of the granulating box, and a drying box is fixedly connected to one end of the first connecting pipe. According to the utility model, the spiral structure can ensure that materials are conveyed to a granulation area at a relatively uniform speed and flow, so that the unstable supply of the materials is avoided, the stability of the granulation quality is favorably ensured, the materials can be conveyed in a relatively closed space in a spiral manner, the pollution of external factors to medicine raw materials can be effectively reduced, and the production efficiency is improved. And meanwhile, leakage of medicine raw materials can be avoided.
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Description

TECHNICAL FIELD

[0001] The utility model relates to medicine preparation device technical field especially relates to a medicine production is with pelletizer. BACKGROUND

[0002] Solid preparation is the most one kind of dosage form that we contact, such as the medicine tablet and capsule that we often take. A problem is discovered to a large number of compounds with new treatment function in modern society, how is better protection to operating personnel in production, especially for the active ingredient containing biological pharmaceutical and anticancer drug, this part of drug not only will be harmful to operating personnel, also can destroy the living environment, still have a part of drug, if in the general environment, also can be contaminated, the curative effect of this drug can be destroyed. Therefore, how to protect operating personnel, protect the environment and protect the medicine, the pharmaceutical equipment manufacturer pays more and more attention to the problem, the airtightness is based on the consideration of health and safety of some foreign pharmaceutical enterprises, aims at the complete isolation of product and human and outside environment, eliminates all bad influences.

[0003] In the prior art, the temperature of the oral tablet coming out of the drying box is high, which is inconvenient for the workers to package and may cause the particles to stick together, deform and other problems due to the high temperature, and even may affect the stability and quality of the medicine. The medicine raw materials may be contaminated when contacting the outside environment during pouring, and the granulation quality cannot be guaranteed due to the uneven pouring of the raw materials. UTILITY MODEL CONTENT

[0004] The utility model aims at solving the shortcomings in the prior art and provides a pelletizer for medicine production.

[0005] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a pelletizer for medicine production, including pelletizing box and drying box, the pelletizing box top is connected with conveying cylinder through pipeline, one end of conveying cylinder is fixedly connected with first motor, one side of conveying cylinder is connected with storage bin through pipeline, the bottom of storage bin is fixedly connected with support column, the outer surface of pelletizing box is fixedly connected with frame, the bottom of pelletizing box is fixedly connected with first connecting pipe, and one end of first connecting pipe is fixedly connected with drying box, the bottom of drying box is fixedly connected with second connecting pipe, and the bottom of second connecting pipe is fixedly connected with shell, one side of shell is fixedly connected with second motor.

[0006] Further description of the above technical scheme:

[0007] The inner surface of main shaft is fixedly connected with spiral blade, and the output end of first motor penetrates shell and is fixedly connected with main shaft.

[0008] As a further description of the above technical solutions:

[0009] The outer surface of the drying box is fixedly connected with a circular pipe, the front side of the circular pipe is fixedly connected with a hot air box through a pipe, the first filter screen is fixedly connected with the opening at the front side of the hot air box, and the hot air fan is fixedly connected inside the drying box.

[0010] As a further description of the above technical solutions:

[0011] The rear side of the shell is fixedly connected with a cold air box, one side of the cold air box penetrates through the rear side of the shell, the cold air fan is fixedly connected inside the cold air box, and the second filter screen is fixedly connected with the opening at one side of the cold air box.

[0012] As a further description of the above technical solutions:

[0013] The output end of the second motor penetrates through the shell and is fixedly connected with a transmission roller, one transmission roller is further rotatably connected inside one side of the shell, and the conveying belt is sleeved between the two transmission rollers.

[0014] As a further description of the above technical solutions:

[0015] Valves are arranged at the intermediate positions of the first connecting pipe and the second connecting pipe.

[0016] As a further description of the above technical solutions:

[0017] The extrusion screen plate is fixedly connected at the intermediate position inside the granulating box, the third motor is fixedly connected at the intermediate position at the top of the extrusion screen plate, the output end of the third motor penetrates through the extrusion screen plate and is fixedly connected with a scraper, the two electric push rods are fixedly connected at the peripheral positions at the top of the granulating box, and one end of each electric push rod penetrates through the top of the granulating box and is fixedly connected with a pressing plate.

[0018] The utility model has the advantages of the following beneficial effects:

[0019] 1. The granulator for medicine production provided by the utility model can realize continuous and stable material conveying through the internal structure main shaft and spiral blade of the conveying cylinder, the spiral structure can ensure that the material is conveyed to the granulating area at a relatively uniform speed and flow, avoids the uneven supply of the material, helps to ensure the stability of the granulating quality, the spiral type can transport the material in a relatively closed space, can effectively reduce the pollution of external factors to the medicine raw materials, and can also avoid the leakage of the medicine raw materials, which is very important in the scene of medicine production which has high requirements on health and raw material loss control.

[0020] 2. The granulator for medicine production provided by the utility model, firstly, the drying box is used for heating, the temperature of the dried particles is high, if the subsequent packaging or storage operation is directly carried out, the particles may be bonded or deformed due to the high temperature, and even the stability and quality of the medicine may be affected. The cold air box can rapidly reduce the temperature of the particles by blowing cold air to the particles, so that the particles are rapidly cooled to room temperature or close to room temperature, thereby avoiding the above problems and ensuring the physical form and quality stability of the particles. BRIEF DESCRIPTION OF DRAWINGS

[0021] Figure 1 A perspective view of the granulator for medicine production is provided for the utility model;

[0022] Figure 2 A sectional view of the granulator for medicine production is provided for the utility model;

[0023] Figure 3 A sectional view of the granulating box of the granulator for medicine production is provided for the utility model;

[0024] Figure 4 An internal structure diagram of the conveying cylinder of the granulator for medicine production is provided for the utility model.

[0025] LEGEND:

[0026] 1, support column; 2, storage bin; 3, first motor; 4, conveying cylinder; 5, granulating box; 6, frame; 7, cold air box; 8, hot air box; 9, valve; 10, second motor; 11, shell; 12, conveying belt; 13, first filter screen; 14, air cooler; 15, second filter screen; 16, transmission roller; 17, circular ring pipeline; 18, drying box; 19, air heater; 20, main shaft; 21, spiral blade; 22, first connecting pipe; 23, second connecting pipe; 24, electric push rod; 25, pressing plate; 26, extrusion screen plate; 27, scraper; 28, third motor. DETAILED DESCRIPTION

[0027] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the protection scope of the utility model.

[0028] In the description of the utility model, it is necessary to explain, the term "center", "upper", "lower", "left", "right", "vertical", "horizontal", "internal", "external" and so on indicate the orientation or position relation based on the orientation or position relation shown in the drawing, only for the convenience of describing the utility model and simplifying the description, and not indicate or imply that the device or element indicated must have a particular orientation, a particular orientation and operation, therefore, it cannot be understood as a limitation on the utility model;The terms "first", "second", "third" are only for the purpose of description, and cannot be understood as indicating or implying relative importance, in addition, unless otherwise specified and limited, the terms "mounting", "connecting", "connecting" should be broadly understood, for example, it can be fixedly connected, or it can be detachably connected, or integrally connected;It can be mechanically connected, or electrically connected;It can be directly connected, or indirectly connected through an intermediate medium, it can be the communication between two elements inside. For ordinary skilled in the art, the specific meaning of the above terms in the utility model can be understood according to the specific circumstances.

[0029] Referring to Figures 1-4 The utility model provides a kind of embodiment: a kind of granulator for medicine production, including granulating box 5 and drying box 18, granulating box 5 top is connected with conveying cylinder 4 by pipeline, can be evenly delivered to raw material, conveying cylinder 4 one end is fixedly connected with first motor 3, first motor 3 can drive the structure inside conveying cylinder to rotate movement, conveying cylinder 4 side is connected with storage bin 2 by pipeline, and the raw material needed is stored together, storage bin 2 bottom four corners are fixedly connected with support column 1, granulating box 5 outer surface is fixedly connected with frame 6, frame 6 not only fixed granulating box 5 still hot blast box 8 and drying box 18 are fixed together to prevent falling off, granulating box 5 bottom is fixedly connected with first connecting pipe 22 and one end of first connecting pipe 22 is fixedly connected with drying box 18, and raw materials made are transported to next equipment by these pipelines, drying box 18 bottom middle position is fixedly connected with second connecting pipe 23 and is fixedly connected with shell 11, one side of shell 11 is fixedly connected with second motor 10.

[0030] The middle position of the conveying cylinder 4 is provided with a main shaft 20, and the surface of the main shaft 20 is fixedly connected with a spiral blade 21, which stably and uniformly conveys the raw materials into the granulating box 4. The output end of the first motor 3 penetrates the shell 11 and is fixedly connected with the main shaft 20. The outer surface of the drying box 18 is fixedly connected with a circular annular pipe 17, and the front side of the circular annular pipe 17 is fixedly connected with a hot air box 8 through a pipe. The hot air generated by the hot air fan 19 is blown into the drying box 18 through the uniformly distributed pipes on the outer side of the drying box 18. The first filter screen 13 is fixedly connected to the opening at the front side of the hot air box 8, which prevents some impurities from entering and affecting the medicine. The hot air fan 19 is fixedly connected inside the drying box 18. The cold air box 7 is fixedly connected to the rear side of the shell 11, and one side of the cold air box 7 penetrates the rear side of the shell 11. The cold air fan 14 is fixedly connected inside the cold air box 7. The particles passing through the drying box 18 are cooled to prevent coagulation under high temperature. The second filter screen 15 is fixedly connected to the opening at one side of the cold air box 7, which also prevents some impurities from entering and affecting the medicine. The output end of the second motor 10 penetrates the shell 11 and is fixedly connected with a transmission roller 16. One transmission roller 16 is also rotatably connected inside one side of the shell 11. The conveying belt 12 is sleeved between the two transmission rollers 16. The cooled particles can be transported away by using the conveying belt 12. The valve 9 is arranged at the middle position of the first connecting pipe 22 and the second connecting pipe 23. The valve 9 can control the outflow of the particles. The extrusion screen plate 26 is fixedly connected to the middle position inside the granulating box 5. The third motor 28 is fixedly connected to the middle position of the top of the extrusion screen plate 26. The output end of the third motor 28 penetrates the extrusion screen plate 26 and is fixedly connected with a scraper 27. The third motor 2 drives the scraper 27 to cut the extruded raw materials into the required shape. Two electric push rods 24 are fixedly connected to the top of the granulating box 5. One end of each electric push rod 24 penetrates the top of the granulating box 5 and is fixedly connected with a pressing plate 25.

[0031] Working principle: The raw materials needed to be made into particles are stored in the storage bin 2. The raw materials are transported to one end of the conveying cylinder 4 through the pipe below. The first motor 3 is started to drive the rotation of the main shaft 20 and the spiral blade 21, which uniformly transfers the raw materials into the granulating box 5. The third motor 28 is started to drive the rotation of the scraper 27. The raw materials extruded by the electric push rod 24 and the pressing plate 25 are extruded from the extrusion screen plate 26 and cut into the required granular shape. When passing through the first pipe 22, the valve 9 can be opened to allow the particles to fall into the drying box 18. The hot air generated by the hot air fan 19 is blown into the annular pipe 17 through the first filter screen 13, and then the hot air is uniformly blown into the drying box 18 through the pipe of the annular pipe 17. The cut particles are dried. After drying, the second connecting pipe 23 is used to convey the particles into the shell 11 for cooling. The cold air fan 14 blows the air filtered by the second filter screen 15 into the shell 1. The second motor 10 is started to rotate the transmission roller 16 and drive the conveying belt 12. The cooled particles are conveyed out for packaging.

[0032] It should be pointed out finally that: the above only for the preferred embodiments of the present application and is not intended to limit the present application, although the present application has been described in detail with reference to the foregoing embodiments, for those skilled in the art, it still can be modified to the technical solutions recorded in the foregoing embodiments, or for some of the technical features of the equivalent replacement, any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application, should be included within the scope of the present application.

Claims

1. A granulator for pharmaceutical production, comprising a granulation tank (5) and a drying tank (18), characterized in that: The top of the granulating box (5) is connected with a conveying cylinder (4) through a pipeline, one end of the conveying cylinder (4) is fixedly connected with a first motor (3), one side of the conveying cylinder (4) is connected with a storage bin (2) through a pipeline, the bottom of the storage bin (2) is fixedly connected with a supporting column (1) at four corners, the outer surface of the granulating box (5) is fixedly connected with a frame (6), the bottom of the granulating box (5) is fixedly connected with a first connecting pipe (22), one end of the first connecting pipe (22) is fixedly connected with a drying box (18), the bottom of the drying box (18) is fixedly connected with a second connecting pipe (23) at the middle position, and the bottom of the second connecting pipe (23) is fixedly connected with a shell (11), one side of the shell (11) is fixedly connected with a second motor (10).

2. The granulator as claimed in claim 1, wherein: The inner middle position of the conveying cylinder (4) is provided with a main shaft (20), and the surface of the main shaft (20) is fixedly connected with a spiral blade (21), and the output end of the first motor (3) penetrates the shell (11) and is fixedly connected with the main shaft (20).

3. The granulator as claimed in claim 1, wherein: The outer surface of the drying box (18) is fixedly connected with a circular ring pipeline (17), and the front side of the circular ring pipeline (17) is fixedly connected with a hot air box (8) through a pipeline, the front side of the hot air box (8) is fixedly connected with a first filter screen (13), and the inner surface of the drying box (18) is fixedly connected with a hot air fan (19).

4. The granulator as claimed in claim 1, wherein: The rear side of the shell (11) is fixedly connected with a cold air box (7), and one side of the cold air box (7) penetrates the rear side of the shell (11), the inner surface of the cold air box (7) is fixedly connected with a cold air fan (14), and one side of the cold air box (7) is fixedly connected with a second filter screen (15).

5. The granulator as claimed in claim 1, wherein: The output end of the second motor (10) penetrates the shell (11) and is fixedly connected with a transmission roller (16), and one side of the shell (11) is also rotatably connected with a transmission roller (16), and a conveying belt (12) is arranged between the two transmission rollers (16).

6. The granulator as claimed in claim 1, wherein: The middle positions of the first connecting pipe (22) and the second connecting pipe (23) are provided with valves (9).

7. The granulator as claimed in claim 1, wherein: The inner middle position of the granulating box (5) is fixedly connected with an extrusion screen plate (26), the top middle position of the extrusion screen plate (26) is fixedly connected with a third motor (28), the output end of the third motor (28) penetrates the extrusion screen plate (26) and is fixedly connected with a scraper (27), and the top of the granulating box (5) is fixedly connected with two electric push rods (24), one end of the electric push rod (24) penetrates the top of the granulating box (5) and is fixedly connected with a pressing plate (25).