Dose counter and inhaler

Abstract

The present application discloses a dose counter and an inhaler, the dose counter adapted for an inhaler, the dose counter comprising: an actuating mechanism configured to move towards a distal end when driven; the counting assembly comprises a first counting unit and a second counting unit; the first counting unit is driven by the actuating mechanism to count a first group of numbers when the actuating mechanism moves towards the far end, and drives the second counting unit to count a second group of numbers when the first counting unit counts for a preset number of times; and the first counting unit and the second counting unit are matched with each other to indicate the use times of the inhaler in a visual number.

Description

Technical Field

[0001] This application relates to the field of inhaler technology, specifically to a dose counter and an inhaler. Background Technology

[0002] As a medical device, an inhaler can include pressure metered-dose inhalers and dry powder metered-dose inhalers. Inhalers can be respiratory-actuated, meaning they release and deliver medication to the patient in response to the user's exhalation, thereby achieving a therapeutic purpose.

[0003] Generally, inhalers store multiple doses of medication. Since the medication usage information cannot be displayed on the inhaler's exterior, users cannot know how much medication is left after each dose. This makes it uncertain whether a complete dose will be available for the next use. Furthermore, users cannot prepare spare inhalers in advance. Consequently, users may experience adverse consequences such as decreased treatment effectiveness, disease recurrence, or gradual worsening of the disease due to insufficient dosage or interruption of medication.

[0004] Therefore, how to accurately count and display the dosage used after each dose of medication to the user is a technical problem that urgently needs to be solved. Summary of the Invention

[0005] In view of the shortcomings of the above-mentioned related technologies, the purpose of this application is to provide a dose counter and a respiratory-actuated inhaler to overcome the problem in the above-mentioned related technologies of how to accurately count and display the dosage used to the user after each dose of medication is used.

[0006] To achieve the above and other related objectives, a first aspect of this application discloses a dose counter suitable for an inhaler. The dose counter includes: an actuation mechanism configured to move distally when driven; and a counting assembly including a first counting unit and a second counting unit. The first counting unit is driven by the actuation mechanism to count a first set of numbers when the actuation mechanism moves distally, and drives the second counting unit to count a second set of numbers when the first counting unit counts a preset number of times. The first counting unit and the second counting unit cooperate to visually indicate the number of times the inhaler has been used.

[0007] A second aspect of this application discloses a dose counter suitable for an inhaler, the dose counter comprising: an actuation mechanism configured to move distally when driven; a counting component for counting the number of uses of the inhaler based on the distally moving motion of the actuation mechanism, the counting component indicating the number of uses of the inhaler by presenting a visualized number in a display window; and a signal element connected to the counting component for being driven by the counting component to appear in the display window to prompt the user when the number of uses of the inhaler reaches a preset number of uses.

[0008] The third aspect of this application discloses a dose counter suitable for an inhaler, the dose counter comprising: an actuation mechanism configured to move distally when driven; a counter housing having a display window thereon; and a counting component housed in the counter housing for counting the number of uses of the inhaler based on the distally moving motion of the actuation mechanism, the counting component indicating the number of uses of the inhaler by presenting a visualized number in the display window; wherein a display element is configured on the display window to magnify the number in the display window.

[0009] The fourth aspect of this application discloses an inhaler including a dose counter as described in any one of the first, second, and third aspects of this application.

[0010] The fifth aspect of this application discloses a respiratory-actuated inhaler, comprising: a main housing having a mouthpiece at its distal end; a canister containing a drug solution, disposed axially within the main housing; a force-holding unit attached to the main housing and engaging the canister to activate the canister in response to inhalation by a user through the mouthpiece; a support connected to the force-holding unit for positioning the force-holding unit; and a dose counter, as described in any one of the first, second, and third aspects of this application, disposed within the main housing for counting the number of uses of the inhaler.

[0011] In summary, the dose counter and respiratory-actuated inhaler disclosed in this application achieve accurate counting of usages by incorporating a cooperating first and second counting unit in the counting assembly and using the cooperating first and second counting units to visually indicate the number of times the inhaler has been used. Furthermore, a signal element is included to alert the user and draw the patient's / user's attention to the remaining dose in the inhaler.

[0012] Other aspects and advantages of this application will readily be apparent to those skilled in the art from the detailed description below. Only exemplary embodiments of this application are shown and described in the following detailed description. As will be appreciated by those skilled in the art, the content of this application enables them to make modifications to the disclosed specific embodiments without departing from the spirit and scope of the invention to which this application pertains. Accordingly, the descriptions in the accompanying drawings and specification of this application are merely exemplary and not restrictive. Attached Figure Description

[0013] The specific features of the invention involved in this application are shown in the appended claims. The features and advantages of the invention can be better understood by referring to the exemplary embodiments and drawings described in detail below. A brief description of the drawings is as follows:

[0014] Figure 1 The diagram shown is a schematic representation of the external structure of a respiratory-actuated inhaler in one embodiment of this application.

[0015] Figure 2 The diagram shown is a schematic representation of the internal structure of a respiratory-actuated inhaler in one embodiment of this application.

[0016] Figure 3 The diagram shown is a structural schematic of the main housing from one perspective in one embodiment of this application.

[0017] Figure 4 The diagram shown is a schematic structural diagram of the main housing from one perspective in one embodiment of this application.

[0018] Figure 5 The diagram shown is a structural schematic of a force-holding unit in one embodiment of this application.

[0019] Figure 6 The diagram shown is a structural schematic of the diaphragm in one embodiment of this application.

[0020] Figure 7 The diagram shown is a structural schematic of the bracket in one embodiment of this application.

[0021] Figure 8 The diagram shown is a schematic representation of the inhaler in a dormant state in one embodiment of this application.

[0022] Figure 9 Displayed as Figure 8 The diagram shows the force-holding unit in a dormant state.

[0023] Figure 10 The diagram shown is a schematic representation of an inhaler in a ready state in one embodiment of this application.

[0024] Figure 11This diagram shows the force-holding unit of the inhaler in the activated state.

[0025] Figure 12 and Figure 13 The following are schematic diagrams of the dose counters in different embodiments of this application.

[0026] Figure 14 This application is displayed as being in Figure 12 The illustrated embodiment shows a schematic diagram of the actuator moving to the distal end.

[0027] Figure 15 The diagram shown is a structural schematic of the propulsion unit in one embodiment of this application.

[0028] Figure 16 The diagram shown is a schematic diagram of the split structure of the first counting unit and the second counting unit in one embodiment of this application.

[0029] Figure 17 and Figure 18 The diagrams shown are schematic representations of the structure of the first counting unit in different embodiments.

[0030] Figure 19 The diagram shown is a structural schematic of the propulsion unit in one embodiment of this application.

[0031] Figure 20 This application is displayed as being in Figure 19 The diagram shows the operational state of the stopping structure in the propulsion unit.

[0032] Figure 21 The diagram shown is a schematic representation of the digits displayed by the counting component in one embodiment of this application being offset from the display window.

[0033] Figure 22 This application is displayed as being in Figure 12 The illustrated embodiment shows a schematic diagram of the actuator moving towards the proximal end.

[0034] Figure 23 The diagram shows, in one embodiment of this application, a digit displayed by the counting component correctly displayed in a display window.

[0035] Figure 24 The diagram shown is a schematic representation of the counting component from one perspective in one embodiment of this application.

[0036] Figure 25 and Figure 26 The diagrams shown are schematic representations of the signal elements in different embodiments of this application.

[0037] Figure 27 The diagram shown is a schematic representation of the engagement of a signal element and a second counting wheel in one embodiment of this application.

[0038] Figure 28 This application is shown to include Figure 25 The schematic diagram of the counting component in the embodiment of the signal element shown is a structural diagram.

[0039] Figure 29 This application is displayed as being in Figure 25 The diagram shown illustrates the relative positional relationship between the signal element and the actuation mechanism in the embodiment shown.

[0040] Figures 30 to 33 The images shown are three-dimensional structural schematic diagrams of the upper housing of the inhaler in different embodiments of this application.

[0041] Figures 34 to 37 They are displayed as Figures 30 to 33 The illustrated embodiment is shown as a schematic diagram from another perspective.

[0042] Figure 38 The diagram shown is a partial schematic of the proximal end of the upper housing in one embodiment of this application.

[0043] Figure 39 The diagram shown is a schematic representation of the proximal end face of the upper housing in one embodiment of this application.

[0044] Figure 40 This is a schematic diagram illustrating the testing of test cases in this application.

[0045] Figure 41 The diagram shown is a schematic representation of the air inlet structure in the comparative example of this application.

[0046] Figure 42 This is a schematic diagram illustrating the comparative tests performed in this application.

[0047] Figure 43 The diagram shows line graphs of gas flow resistance tests in the test examples and comparative examples of this application.

[0048] Figure 44 The diagram shows line graphs of gas flow resistance tests in the test examples and comparative examples of this application. Detailed Implementation

[0049] The following specific embodiments illustrate the implementation of this application. Those skilled in the art can easily understand the advantages and technical effects of this application from the content disclosed in this specification.

[0050] In the following description, some embodiments may be referenced to the accompanying drawings. It should be understood that other embodiments not shown in the drawings may also be used, and specific structural, component, mechanism, and operational changes may be made without departing from the spirit and scope of this application. The following detailed description should not be considered limiting, and the scope of the embodiments of this application is defined only by the claims published herein. The terminology used herein is for describing particular embodiments only and is not intended to limit the application.

[0051] While the terms first, second, etc., are used in some instances herein to describe various elements or parameters, these elements or parameters should not be limited by these terms. These terms are used only to distinguish one element or parameter from another. For example, a first counting unit may be referred to as a second counting unit, and similarly, a second counting unit may be referred to as a first counting unit, without departing from the scope of the various described embodiments. Both the first counting unit and the second counting unit describe a counting unit, but they are not the same counting unit unless the context otherwise clearly indicates otherwise.

[0052] Furthermore, as used herein, the singular forms “a,” “an,” and “the” are intended to include the plural forms as well, unless the context indicates otherwise. It should be further understood that the terms “comprising,” “including,” and “including” indicate the presence of the stated features, steps, operations, elements, components, items, kinds, and / or groups, but do not exclude the presence, occurrence, or addition of one or more other features, steps, operations, elements, components, items, kinds, and / or groups. For example, a process, method, system, product, or device that comprises a series of steps or units is not necessarily limited to those steps or units explicitly listed, but may include other steps or units not explicitly listed or inherent to these processes, methods, products, or devices. Additionally, the term “and / or,” which may be used hereinafter, describes the relationship between related objects, indicating that three relationships may exist; for example, A and / or B can represent: A alone, A and B simultaneously, and B alone. Furthermore, the character “ / ”, unless otherwise specified, generally indicates that the preceding and following related objects have an “and / or” relationship. Additionally, in the description of embodiments of this application, “multiple” refers to two or more. Furthermore, the terms “or” and “and / or” as used herein are interpreted as inclusive, or mean either one or any combination thereof. Exceptions to this definition only arise when a combination of elements, functions, steps, or operations is inherently mutually exclusive in some way.

[0053] It should also be understood that when an element, such as a layer, region, or substrate, is referred to as being "on" another element or extending "on" another element, the element may be directly on or directly extending onto the other element, or intermediate elements may be present. Conversely, when an element is referred to as being "directly on" another element or "directly extending onto" another element, no intermediate elements are present. It will also be understood that when an element is referred to as being "connected" or "attached" to another element, it may be directly connected or coupled to the other element, or intermediate elements may be present. Conversely, when an element is referred to as being "directly connected" or "directly coupled" to another element, no intermediate elements are present. Furthermore, the term "coupled" generally means physical, mechanical, magnetic, and / or electrical coupling or connection, and in the absence of specific contrasting language, the presence of intermediate elements between coupled or associated items is not excluded.

[0054] Relative terms such as “below,” “above,” “upper,” “lower,” “horizontal,” or “vertical” may be used herein to describe the relationship between one element, layer, or region and another element, layer, or region illustrated in the figures. It will be understood that these terms are intended to cover different device orientations other than those depicted in the figures. In this application, “vertical,” “horizontal,” and “parallel” are defined as including cases within ±10% of the standard definition. For example, vertical typically refers to an angle of 90° relative to a reference line, but in this application, vertical refers to cases including those within 80° to 100°. Unless otherwise expressly stated, comparative quantitative terms (such as “above” and “below”) are intended to cover the concept of equality. As an example, “above” can mean not only “greater than” in a mathematical sense but also “equal to.”

[0055] Unless otherwise specified, all terms used herein (including technical and scientific terms) shall have the same meaning as commonly understood by one of ordinary skill in the art to which this application pertains. It will also be understood that terms used herein shall be interpreted as having the meaning consistent with their meaning in the context of this specification and the relevant field, and shall not be interpreted in an idealized or overly formal sense unless expressly so defined herein.

[0056] In some embodiments provided in this application, a dose counter and an inhaler using the same are disclosed. The dose counter counts a first set of numbers through a first counting unit, and drives a second counting unit to count a second set of numbers when counting a preset number of times, so that the two sets of numbers from the two counting units can be combined together to visually indicate the number of times the inhaler has been used.

[0057] In some embodiments of this application, the number of times the inhaler is used can refer to either the remaining number of uses of the inhaler or the number of times the inhaler has already been used. To facilitate differentiation between these two examples of the number of uses in subsequent embodiments, in examples where the number of uses specifically refers to the remaining number of uses of the inhaler, the number of uses will be referred to as the remaining number of uses or the number of unused uses; in examples where the number of uses specifically refers to the number of times the inhaler has already been used, the number of uses will be referred to as the number of used uses. The amount of solution dispensed per use of the inhaler corresponds to one dose; in other words, counting the number of times the inhaler is used is equivalent to counting the dose of the inhaler.

[0058] In some embodiments of this application, the indicated number of uses of the inhaler may include at least one of the number of uses during production phase testing and the number of uses after leaving the factory. For example, the indicated number of uses of the inhaler may include the number of uses during production phase testing; that is, two counting units working together can visually indicate the number of uses of the inhaler during production phase testing, thus facilitating user monitoring of the testing process. Alternatively, the indicated number of uses of the inhaler may include the number of uses after leaving the factory; that is, two counting units working together can visually indicate the number of uses of the inhaler after leaving the factory. The number of uses after leaving the factory generally corresponds to actual use, thus allowing users to understand the inhaler's usage status in real time. This enables users to replenish inhalers in a timely manner and avoids misuse of inhalers after they have been used up, which could delay the user's treatment. Furthermore, the indicated number of uses of the inhaler may include both the number of uses during production phase testing and the number of uses after leaving the factory, thus facilitating both user monitoring of the testing process and real-time understanding of the inhaler's usage status.

[0059] In this application, for ease of describing positional relationships, the end facing the inhalation port of the inhaler is defined as the distal end (as shown in the image). Figure 1 The Z2 direction indicator is the distal end, and the end furthest from the inhaler's inlet is defined as the proximal end (as shown in the image). Figure 1 The Z1 direction in the figure indicates the proximal end.

[0060] In this application, the term "user" refers to the user of the inhaler, who may be, for example, a tester, a patient, or a subject. Depending on the specific identity of the user, in some embodiments, the user may also be referred to as a tester, a patient, or a subject.

[0061] In some embodiments of this application, the initial state refers to the state of the inhaler when it leaves the factory; the dormant state refers to the state of the inhaler when it is placed aside or stored, for example... Figure 2In the state presented, the inhaler's dust cover 6 is closed, and the force-holding unit 4 is maintained at its reachable proximal limit position. Therefore, in some embodiments, the state of the structure or unit of the inhaler in its dormant state is also referred to as the proximal state. In some embodiments, the ready state refers to the state in which the inhaler is triggered from the dormant state to wait to be activated for drug dispensing, for example... Figure 1 The image shows the state when the dust cover is open. In some embodiments, the activation state refers to the state presented in response to the user's inhalation and medication dispensing. In some embodiments, the reset state refers to the process of returning the inhaler to a dormant state after dispensing, for example, by... Figure 1 The dust cover that has been opened rotates to Figure 2 The process of closing the state.

[0062] In some embodiments of this application, a respiratory-actuated inhaler is proposed, which is configured to initiate a drug dispensing in response to a user's inhalation. The dispensed drug is then delivered into the user's respiratory tract and lungs via a soft mist or particles, along with the user's inhalation airflow, thereby achieving a therapeutic purpose.

[0063] Please see Figure 1 and Figure 2 , Figure 1 The diagram shown is a schematic representation of the external structure of a respiratory-actuated inhaler in one embodiment of this application. Figure 2 The figure shows a schematic diagram of the internal structure of a respiratory-actuated inhaler in one embodiment of the present application. As shown, the respiratory-actuated inhaler includes a main housing 1, a canister 2, a force-holding unit 4, a support 3, and a dose counter 5.

[0064] Please see Figure 3 and combined Figure 1 As shown, Figure 3 The diagram shown is a schematic representation of the main housing from one perspective in one embodiment of this application. The distal end of the main housing 1 has a suction port 10. The suction port 10 provides an interface for a user to breathe in, and has a chamber 100. A dispensing port on the canister 2 or a dispensing port communicating with the canister 2 extends into the chamber 100, so that the drug dispensed through the dispensing port enters the user's mouth through the chamber 100.

[0065] Please see Figure 4 The image shown is a schematic diagram of the main housing structure from one perspective in one embodiment of this application, and is combined with... Figure 2As shown, the main housing 1 has a counting space 11 for arranging the dose counter 5. The counting space 11 can be formed by an inward recess of the main housing 1. In one example, the counting space 11 is located at the distal end of the main housing 1 and on the opposite side of the suction port 10 (it can also be understood that the counting space 11 is located opposite to the suction port 10). Further, a hole structure 110 is provided on the counting space 11. The hole structure 110 can be formed on the proximal sidewall of the counting space 11. The hole structure 110 allows at least a portion of the structure of the support 3 to pass through to drive the dose counter 5. Figure 2 and Figure 4 As shown in the example, the support 3 has a drive rod 30 that extends through the hole structure 110 for driving the dose counter 5 to count. The structures of the support 3 and the dose counter 5 will be described in detail later and will not be repeated here.

[0066] In one embodiment, such as Figure 2 and Figure 3 As shown, the main housing 1 also has an installation space 12 for accommodating the tank 2. The installation space 12 is a groove, recess, or similar structure pre-formed on the main housing 1 to accommodate the tank 2.

[0067] In one embodiment, such as Figure 1 and Figure 2 As shown, a dust cover 6 is also connected to the main housing 1, and the dust cover 6 is rotatably connected to the main housing 1. In one example, as... Figure 3 As shown, a connecting pin 12 is provided at the far end of the main housing 1, and the dust cover 6 has a groove (not shown) that matches the connecting pin 12. The connecting pin 12 engages with the groove so that the dust cover 6 is rotatably disposed at the far end of the main housing 1.

[0068] In one embodiment, the dust cover 6 has a protrusion. When the dust cover 6 moves from the open state to the closed state, the protrusion cooperates with the bracket 3 to push the bracket 3 toward the proximal end, thereby locking the dust cover 6 in the closed state. The specific process will be described in detail later and will not be repeated here.

[0069] The canister 2 is used to store multiple doses of drug solution and can also be used for quantitative dispensing of drug solution. The canister 2 is axially disposed within the main housing 1. Specifically, the bottom of the canister 2 is positioned proximally within the mounting space 12 of the main housing 1, or alternatively, the canister 2 can be described as being inverted and inserted into the mounting space 12 of the main housing 1. The drug solution includes an active pharmaceutical ingredient and a pharmaceutical composition for therapeutic purposes. The active pharmaceutical ingredient is related to the disease for which the respiratory-actuated inhaler is used to treat. The active pharmaceutical ingredient includes, but is not limited to, anti-inflammatory drugs, β2-adrenergic receptor agonists, anticholinergic drugs, antihistamines, serotonin agonists, and combinations thereof. The pharmaceutical composition includes at least one of a propellant (also referred to as a jet), a solubilizer, and a surfactant. The propellant is used to atomize the drug within the canister. Examples of propellants include tetrafluoroethane (HFA134a) and heptafluoropropane (HFA227). Examples of solubilizers include ethanol and glycerin. Examples of surfactants include oleic acid.

[0070] In one embodiment, such as Figure 2 As shown, the container 2 includes a container body 20, a valve 21, and a valve stem 22. The container body 20 has an internal space for holding multiple doses of drug solution. The valve 21 (also referred to as a metering valve) communicates with the interior of the container body 20 to control the dosage. The valve 21 includes a metering chamber with a communication port that communicates with the interior of the container body 20. The metering chamber can be filled with or emptied with a dose of drug solution. In one embodiment, the dosage can be controlled by controlling the volume of the metering chamber.

[0071] The valve stem 22 is a hollow stem. The distal end of the valve stem 22 has a dispensing port that allows the drug solution to drain, and the proximal end of the outer diameter surface of the valve stem 22 has an inlet that allows the drug solution to enter. Specifically, the valve stem 22 is spring-loaded onto the valve 21. Due to external force, the valve stem 22 moves relative to the can body 20 and compresses the spring. When the valve stem 22 moves a preset distance, the inlet of the valve stem 22 enters the metering chamber of the valve 21. At this time, a dose of drug solution begins to enter the valve stem through the inlet and drain from the dispensing port of the valve stem 22. Further, when the valve stem 22 continues to move to the stop portion inside the valve 21, the valve stem 22 stops moving. In one example, valve 21 has an internal stop (which may be configured, for example, as a sealing ring at the inlet of the metering chamber). The stop also has a communication port connecting to the interior of the can body 20. When valve stem 22 continues to move to the stop inside valve 21, the communication passage between the metering chamber and the can body 20 is also closed, i.e., the communication port is closed. For example, the proximal end of valve stem 22 also has a sealing surface that can close the communication port when valve stem 22 moves a predetermined distance. When the external force disappears, valve stem 22 moves under the action of a spring to open the communication port. At this time, the drug solution enters the metering chamber from the communication port, and the inlet of valve stem 22 leaves the metering chamber of valve 21.

[0072] like Figure 2 As shown, the force-holding unit 4 is attached to the main housing 1 and engages with the canister 2 to activate the canister 2 in response to the user's inhalation through the suction port 10. The force-holding unit 4 is detachably connected to the main housing 1, for example, by a snap-fit ​​structure. The force-holding unit 4 applies a force toward the distal end to the canister body 20 to activate the canister 2 when the user inhales. Specifically, after being subjected to force, the canister body 20 and valve 21 move toward the distal end, causing the valve stem 22 to move relative to the canister body 20 and valve 21 and enter the metering chamber of valve 21, causing the drug solution in the metering chamber to be sprayed out in a mist from the valve stem 22 until the valve stem 22 stops moving when it reaches the stop portion inside valve 21.

[0073] In one embodiment, please refer to Figure 2 and Figure 5 , Figure 5The diagram shown illustrates the structure of a force-holding unit 4 in one embodiment of this application. The force-holding unit 4 includes an upper housing 40, with an air inlet structure 48 disposed near its proximal end. The air inlet structure 48 and the inhalation port 10 form a gas flow path, allowing the force-holding unit 4 to activate the canister in response to the user's inhalation. Specifically, the force-holding unit 4 is attached to the main housing 1 via the upper housing 40 and is located near the proximal end of the main housing 1. For example, the upper housing 40 receives the portion of the canister 2 protruding from the main housing 1 and is connected to the main housing 1 via a threaded connection or snap-fit. The upper housing 40 and the main housing 1 together constitute the outer shell of the inhaler. For ease of user operation, in some examples, such as... Figure 1 As shown, when the upper housing 40 is attached to the main housing 1, the central axis of the suction port 10 on the main housing 1 and the central axis of the upper housing 40 form a preset angle α. The preset angle α is configured to be greater than 90 degrees. In this way, when the user inhales through the suction port 10, the part corresponding to the upper housing 40 will not cause pressure on other parts of the user's face, which can improve the user experience.

[0074] In practice, users hold the inhaler to inhale. Incorrect operation (also known as misoperation) may cause the user's hand to be at least partially placed on the proximal end of the upper shell. This can easily allow the user's hand to block air from entering the structure, causing the inhaler to malfunction. In some related technologies, this is presented as follows... Figure 40 The schematic diagram of the air inlet structure shown in the comparative example is configured as an array of elongated holes formed on the housing, with the long sides of adjacent holes facing each other. Although the structural design of the air inlet holes can create a gap between the cover and the holes to allow air to enter through the gap, this method of relying solely on the gap to provide air entry results in insufficient airflow power, affecting the use of the inhaler, and may even lead to the inhaler not dispensing enough drug solution each time, affecting the treatment effect without the user's knowledge.

[0075] In view of this, the inhaler disclosed in some embodiments of this application, by configuring the air inlet structure to include at least two holes located at the proximal end of the upper housing of the inhaler, and the at least two holes being arranged in a ring shape with their ends connected, ensures that when the user places a cover on the proximal end face during inhalation, the openings cannot be completely covered, facilitating vertical airflow and thus providing sufficient airflow to ensure the normal operation of the inhaler. It should be noted that the cover mentioned above and subsequently refers to the part of the inhaler that the user contacts in contact with the surface where the air inlet structure is located.

[0076] For example, the covering could refer to the user's finger, or more specifically, the user's index finger or thumb. For instance, the pad of the user's index finger or thumb might be mistakenly placed on the proximal end face of the inhaler's upper housing, covering part of the end face. In this case, to prevent the pad of the user's index finger or thumb from blocking the air inlet, this application designs the arrangement of the holes on the proximal end of the inhaler's upper housing in a ring shape. This ensures that even if the user places their thumb or index finger on the proximal end face due to incorrect operating habits during inhalation, the opening cannot be completely covered. In other words, the main opening of the hole can freely allow air to enter, ensuring sufficient space for airflow to enter and ensuring the airflow required to trigger the inhaler, thereby ensuring the normal operation of the inhaler.

[0077] Please see Figures 30 to 33 The figures shown are three-dimensional structural schematic diagrams of the upper housing of the inhaler in different embodiments of this application. The air inlet structure 48 is disposed at the proximal end of the upper housing 40, for example as follows: Figures 30 to 32 The diagram shows the specific configuration on the end face near the proximal end of the upper housing 40 (e.g., Figure 30 As shown, the air inlet structure 48 is disposed on the top end face of the upper housing 40, or for example, as shown in the figure. Figure 33 The diagram illustrates the specific configuration on the side wall of the upper housing 40 near the proximal end face. The air inlet structure 48 includes at least two holes 480 with main openings, arranged in a ring shape at the proximal end of the upper housing 40, with the holes connected end-to-end. This ring arrangement prevents the main openings of all holes from being completely covered when the user places a covering on the proximal end face during inhalation. This ensures that when the user covers the proximal end face of the inhaler during inhalation, the main openings of the holes are still open for air to freely enter, providing sufficient space for airflow and ensuring the airflow required to trigger the inhaler. It should be understood that the ring arrangement means that all the holes can be connected end-to-end to form a ring, and there is no limitation on the specific shape of the ring.

[0078] Among them, the main opening of the hole is the opening that constitutes the main shape of the hole, with Figures 30 to 32 For example, the main opening of orifice 480 is the opening facing upwards, which allows for airflow in a roughly vertical direction (i.e., along the axis of the inhaler, such as...). Figure 30 (Indicated by the dashed arrow) Enter. Figure 33 For example, the main opening of orifice 480 is an opening facing the peripheral area, which allows airflow in a roughly lateral direction (i.e., generally perpendicular to the axis of the inhaler, such as...). Figure 33 (Indicated by the dashed arrow) Enter.

[0079] In such Figures 30 to 33In the embodiment shown, the cross-section of the proximal end of the upper housing 40 is smaller than that of its distal end. Furthermore, the cross-section of the upper housing 40 gradually decreases from the distal end towards the proximal end, thereby making the sidewalls of the upper housing 40 appear as follows: Figures 30 to 33 The figure shown is frustum-shaped, but it should be understood that... Figures 30 to 33 The shape shown is only an example. The cross-sections of the near end and the far end of the upper housing 40 are not necessarily the same or different. Those skilled in the art can set the upper housing with any shape and structure according to actual needs.

[0080] In this arrangement, at least two holes are arranged in a ring, with the tail of the first hole facing the head of the second hole, the tail of the second hole facing the head of the third hole, and so on, until the tail of the last hole faces the head of the first hole, forming a ring. In the example with only two holes, the tail of the first hole faces the head of the second hole, and the tail of the second hole faces the head of the first hole, forming a ring. It should be noted that the facing relationship between the tail and the head refers to a relative or adjacent relationship, and does not require absolute alignment between the tail and the head.

[0081] In some embodiments, an annular region may be pre-defined at the proximal end of the upper housing 40, and at least two holes may be spaced apart within the annular region, thereby arranging the holes in a ring. The pre-defined annular region refers to a ring shape that is expected to be formed on the proximal end during manufacturing; it is not necessarily required to mark the annular region on the end face of the proximal end of the upper housing 40 beforehand. In other embodiments, multiple arc-shaped regions may be pre-defined at the proximal end of the upper housing 40, with the multiple arc-shaped regions forming a ring overall. Holes or one hole may be spaced apart within each arc-shaped region, thereby arranging all the holes in a ring. The pre-defined multiple arc-shaped regions may correspond to multiple components of the ring shape expected to be formed during manufacturing, for example... Figure 33 As shown, the upper housing 40 has two pre-set arc-shaped regions 482 at its near end, and the holes 480 are arranged in accordance with the arc-shaped regions 482.

[0082] Please see Figures 34 to 37 They are displayed as follows Figures 30 to 33 The illustrated embodiment is a schematic diagram from another perspective, as shown below. Figures 34 to 37As shown, adjacent holes are connected end-to-end (adjacent) by connecting portion 481. It should be understood that, in this embodiment, the aforementioned annular arrangement of at least two holes can be understood as the holes and the connecting portions for connecting adjacent holes forming an annular arrangement. In some examples, the connecting portion 481 may be flush with the main opening of the hole 480, that is, adjacent holes 480 and the connecting portion 481 between them are on the same plane. In some examples, the connecting portion 481 may also protrude or be recessed relative to the hole 480, allowing the hole 481 to extend from the main opening to both sides to the connecting portion 481 to form a lateral opening, such as... Figure 38 The image shown is a partial schematic diagram of the proximal end of the upper housing in one embodiment of this application. Figure 38 The diagram illustrates the recessed proximal end face of the upper housing 40 with the connecting part 481 as an example. This recess allows the hole 480 to also have a lateral opening facing the vertical plane, thus allowing for horizontal orientation (i.e., end face or lateral direction, such as...). Figure 38 The airflow enters (as indicated by the arrow h in the image).

[0083] In one embodiment, the depth of the recess or the height of the protrusion of the connecting portion 481 is configured to be any value from approximately 0.2 mm to 2 mm, for example, approximately 0.2 mm, 0.3 mm, 0.4 mm, 0.5 mm, 0.6 mm, 0.7 mm, 0.8 mm, 0.9 mm, 1.0 mm, 1.1 mm, 1.2 mm, 1.3 mm, 1.4 mm, 1.5 mm, 1.6 mm, 1.7 mm, 1.8 mm, 1.9 mm, 2.0 mm, etc.

[0084] In one embodiment, the area of ​​the connecting portion 481 is smaller than the area of ​​the main opening of the hole 480. This increases the proportion of the area occupied by the hole in the air intake structure, enlarging the air-entry area and facilitating airflow. For example, the area of ​​the connecting portion 481 can be configured to be approximately 2 mm². 2 Up to 10mm 2 Any value in the value, for example, can be configured to approximately 2mm. 2 3mm 2 4mm 2 5mm 2 6mm 2 7mm 2 8mm 2 8.5mm 2 9mm 2 9.5mm 2 10mm 2 Preferably, it can be configured to be approximately 8.5mm. 2 .

[0085] In one embodiment, the hole is configured as an elongated structure, that is, the hole has a long side and a short side, which are used to indicate the relative lengths of the lines in the elongated structure of the hole. It is not required that the long and short sides be straight lines or curves; those skilled in the art can change the shape of the hole based on the teachings of this application and the annular arrangement. Figures 34 to 37 In the illustrated embodiment, hole 480 is configured as an elongated hole, with its long side approximately a straight line. For other examples, please refer to... Figure 39 The image shown is a schematic diagram of the proximal end face of the upper housing in one embodiment of this application, as follows. Figure 39 As shown, hole 480 can be configured as an arc-shaped hole. For example, the arc-shaped hole can be further defined as a circular arc-shaped hole, that is, the overall outline of hole 480 is a smooth circular arc. The arc-shaped hole can also be further defined as a non-circular arc-shaped hole, that is, the overall outline of hole 480 will have a turn or bend (or it can also be understood as the radius of curvature changes), as shown in the figure. Figure 39 As shown, the hole 480 is configured as a non-circular arc hole, and the contour of the arc hole forms a corner 4800. Furthermore, the corner 4800 is the middle region facing the proximal end.

[0086] In some embodiments, the width of the hole is configured to any value between 1mm and 2mm, that is, the distance between the two opposite long sides of the hole 480 can be configured to any value between 1mm and 2mm. For example, it can be configured to approximately 1mm, 1.1mm, 1.2mm, 1.3mm, 1.4mm, 1.5mm, 1.6mm, 1.7mm, 1.8mm, 1.9mm, 2mm, etc., preferably 1.49mm. In some examples, the length of the hole is configured to any value between 2mm and 32mm. For example, it can be configured to approximately 2mm, 4mm, 6mm, 8mm, 10mm, 12mm, 14mm, 16mm, 18mm, 20mm, 22mm, 24mm, 26mm, 28mm, 30mm, 32mm, etc.

[0087] In one embodiment, the holes may be configured as two or more, for example, three, four, five, six, seven, eight, or more. For example... Figure 34 The diagram illustrates a configuration of six 480mm holes. Figure 36 Taking a configuration of 24 holes as an example, Figure 37 The diagram illustrates a configuration of 8 holes (480mm). Figure 39 Taking the configuration of four holes (480) as an example, Figure 35 The number of 480 holes is configured to be higher, but this does not imply a limitation on the number of holes. In some examples, the number of holes is configured to be even and symmetrically distributed. Figure 34As shown in the example, six holes 480 are configured, and the distribution of the six holes 480 is axially symmetrical. Figure 39 As shown in the example, the configuration consists of four holes 480, which are distributed symmetrically. In some examples, the holes are configured with an odd number and are evenly distributed, that is, the holes are arranged at uniform intervals.

[0088] In the use of inhalers, user misoperation may involve unconsciously or unknowingly placing the thumb or index finger on the proximal end face of the inhaler's upper housing. In this case, the user's finger is usually placed on the proximal end face of the inhaler's upper housing from the side away from the user's face, or from the right or left side of the inhaler. In this case, the rear, right, or left holes on the proximal end face of the inhaler's upper housing will inevitably be blocked or partially blocked. Therefore, in one embodiment of this application, the width of the front hole on the proximal end face of the inhaler is greater than the width of the holes on other sides. In this way, when the user misoperates and the finger covers the proximal end face from the rear to the front, it can be ensured that the covered holes (i.e., the holes on the rear or other sides) have smaller air intake areas, and the uncovered holes (at least including the holes on the front) have larger air intake areas, thereby maximizing the airflow intensity. The front side refers to the side closest to the inhaler's inlet, while the rear side refers to the side opposite to the front side and furthest from the inhaler's inlet. When the user is using the device, the front side is usually closer to the user's face.

[0089] In some embodiments, the annular arrangement can be configured as a symmetrical distribution. For example, it can be axially symmetric, rotationally symmetric, or centrally symmetric. In some embodiments, the annular arrangement can be configured as a circular annularity, a near-polygonal annularity, or an irregular annularity. Taking a circular annularity as an example, each hole and each connecting portion can correspond to a partial arc of the circle. Taking a near-polygonal annularity as an example, each hole can correspond to one side of the polygon, and each connecting portion can correspond to a transition segment between sides, such as... Figure 34 As shown, the annular arrangement corresponds to a near-hexagonal ring, wherein the six holes 480 are respectively corresponding to the six sides of the near-hexagon, and the six connecting parts 481 are respectively corresponding to the transition sections between the sides.

[0090] like Figures 30 to 32 In the illustrated embodiment, the annular arrangement of at least two holes 480 can divide the proximal end face into an end face region A surrounded by at least two holes and an end face region B at the outer edge of the at least two holes. It should be noted that in some other embodiments, end face region B may not be included; for example, the inner side of the end face region may be the end face region A surrounded by holes, and the outer side may be the surrounding holes.

[0091] Furthermore, to ensure that the cover does not completely cover the main openings of each hole 480 on the proximal end face, in one embodiment, the inner diameter of end face region A is configured to be no less than the width of the cover. Taking the cover as the user's finger as an example, the inner diameter of end face region A is no less than the width of the finger. It should be understood that in the example where end face region A is a non-circular region, the statement that the inner diameter of end face region A is no less than the width of the cover means that the minimum inner diameter of end face region A is no less than the width of the cover. In this way, it can be ensured that no matter how the user covers the proximal end face, it is impossible to completely cover all the openings facing the proximal end face, so that all or part of the openings facing the proximal end face will always allow air to enter freely, thereby ensuring that the inhaler can be used normally and correctly.

[0092] To facilitate user operation, in some embodiments, combined with Figure 34 and corresponding Figure 30 , Figure 35 and corresponding Figure 31 , Figure 36 and corresponding Figure 32 The end face region B is configured as a bevel or an arc surface. In other embodiments, for example... Figure 33 and Figure 37 In the embodiment shown, the proximal end face of the upper housing 40 can also be divided into an end face region A located in the center and an end face region B extending outward from the central end face region, the end face region B being configured as a slope or an arc surface. Figure 33 and Figure 37 (A and B are not labeled). Thus, when the user holds the inhaler and their hand covers the proximal end face of the upper housing 40 from the distal end of the inhaler, the bevel or curved surface can form a transition area for hand grip, which helps to improve the user's experience.

[0093] In one embodiment, the width of the end face region B is configured to be any value between approximately 3 mm and 4.5 mm, for example, it can be configured to 3 mm, 3.5 mm, 4 mm, 4.5 mm, etc., preferably, it can be configured to 3.92 mm.

[0094] In one embodiment, end face region A and end face region B are configured on different planes. This creates an uneven proximal end face of the upper housing 40, inevitably creating an air gap when the user covers the proximal end face, further facilitating air entry. In some examples, the plane containing end face region B may be configured to be higher than the plane containing end face region A, such as... Figure 35 and its corresponding Figure 31 As shown, the plane containing end face region B is higher than the plane containing end face region A. Each hole 480 connects end face region A and end face region B to facilitate the transition between the regions. Figure 31As shown, the annular arrangement of the holes 480 can be curved as a whole, allowing end face region B to gradually transition to end face region A. In other examples, the plane containing end face region A can also be configured to be higher than the plane containing end face region B. In case of user error, this structure will prevent the cover from fully adhering to the near end face, inevitably creating an air gap at the bottom of the cover.

[0095] In some embodiments, a guide portion (also referred to as an indicator portion) may be provided on the side wall of the main housing. The guide portion serves to prompt the user's fingers to grip the area and can also provide feedback to the user, indicating that the user has operated correctly and is ready for inhalation. In some examples, the guide portion is configured as a raised or recessed point, thereby providing both visual and tactile cues to the user, indicating that the fingers should be placed in the correct area. Of course, in other examples, the guide portion may also be configured as a patterned mark to guide the user's operating habits from a visual perspective; this application does not limit this.

[0096] In any of the above-described embodiments of the air inlet structure of this application, by setting the air structure to have at least two holes arranged in a ring, when the user holds the device during inhalation and places their fingers on the proximal end, the main opening of all the holes cannot be completely covered, thus ensuring that airflow can always enter from the main opening, guaranteeing sufficient airflow, and further enabling the inhaler to work normally. To illustrate the effect of the above-described air inlet structure design, experimental data of test examples and comparative examples are provided here.

[0097] Test case structure:

[0098] In the test case, the air entry structure was configured as follows: Figure 39 As shown, it includes four holes 480, with adjacent holes 480 connected end-to-end by a connecting part 481. The covering used in the test example is a finger simulating the grip posture of a user when using an inhaler to cover the end face.

[0099] Please see Figure 40 The figure shows a schematic diagram of the test example of this application. As shown in the figure, in the test example, the proximal end face of the upper shell of the inhaler is placed under an uncovered cover with an area of ​​1 cm². 2 2cm 2 4cm 2 6cm 2Under the conditions of 20L / min, 40L / min, 60L / min, 80L / min and 100L / min respectively, the gas flow rate of the inhaler inlet was set for testing. The covering material was a cube made by molding clay. In this test example, the airflow resistance test results of the air entry structure in the test example are shown in Table 1.

[0100] Table 1:

[0101]

[0102] Comparative example:

[0103] Please see Figure 41 The figure shows a schematic diagram of an air inlet structure selected in the comparative example of this application. As shown, in this comparative example, the air inlet structure is configured as an array of elongated holes formed on the housing, with the long sides of adjacent holes 70 facing each other, and each hole having its own different opening on the outer surface of the housing. These openings are as follows: Figure 41 Extending in the directions indicated by arrows V (towards the end face) and H (horizontal direction), the structure shown in this comparative example, although employing a grid-like or striped opening design, allows for some gaps (e.g., the gap in the direction of arrow H) when the user's finger or thumb covers the opening of orifice 70, enabling air to enter through these gaps. However, because the user's finger or thumb is soft tissue, when it covers orifice 70, the tissue may sink into the grid, resulting in a very small actual gap space. This leads to high airflow resistance and insufficient power, causing the inhaler to fail to dispense a sufficient amount of drug solution, affecting the treatment effect without the user's knowledge.

[0104] Please see Figure 42 The figure shows a schematic diagram of the comparative example test conducted in this application. As shown, the comparative example uses the same test conditions and covering as the test example to simulate the user's grip posture when using the inhaler, covering the end face with fingers. The proximal end face of the upper shell of the inhaler is placed without covering, and the area of ​​the covering is 1 cm². 2 2cm 2 4cm 2 6cm 2 Under the conditions of 20L / min, 40L / min, 60L / min, 80L / min and 100L / min respectively, the gas flow rate of the inhaler inlet was set for testing. In this comparative example, the covering material was also selected as a cube obtained by molding clay. The airflow resistance test results of the air entry structure in the comparative example are shown in Table 2.

[0105] Table 2:

[0106]

[0107] To facilitate comparison between Table 1 and Table 2, a line graph is generated based on the experimental data from Table 1 and Table 2. Please refer to [link / reference]. Figure 43 The graphs shown are line graphs illustrating the gas flow resistance tests in the test examples and comparative examples of this application, respectively. Figure 43 The line graph (a) in the figure represents the experimental data of the test case. Figure 43 Line graph (b) in the figure represents comparative experimental data. Figure 43 In line graphs (a) and (b), the horizontal axis represents gas velocity (in L / min), and the vertical axis represents airflow resistance (in min / L). The five lines from bottom to top correspond to the areas of no covering and covered areas of 1 cm², respectively. 2 2cm 2 4cm 2 6cm 2 Coverage conditions. From Figure 43 The results show that in the 20L / min to 40L / min range (which can be understood as the low-flow range), the air intake resistance in the comparative model increases rapidly with the increase of the covering area, while the resistance increase in the test case is not significant. This means that when a user's suction power is low due to illness, age, or other factors, for the inhaler in the comparative model, improper operation resulting in excessive coverage of the proximal end face will cause significant resistance, making it difficult to start the inhaler or resulting in insufficient activation. However, for the inhaler in the test case, even if the user improperly covers a large area, the air intake resistance of the air inlet structure is not significantly affected. This is because the air inlet structure in the test case uses a ring-shaped hole design. When the covering simulates the user's finger covering the proximal end face, even with a large coverage area, it cannot completely cover all the main openings. The main openings provide sufficient air intake space, and even with low suction power, the inhaler's usability is not affected.

[0108] Please see Figure 44 The graphs shown are line graphs illustrating the gas flow resistance tests in the test examples and comparative examples of this application, respectively. Figure 44 Lines (a) to (e) in the diagram represent the areas of no covering and covered areas of 1 cm², respectively. 2 2cm 2 4cm 2 6cm 2 The comparative experimental data of the test case (represented by dashed lines) and the comparative example (represented by solid lines) under the coverage conditions are shown. The horizontal axis represents the gas flow rate (unit: L / min), and the vertical axis represents the airflow resistance (unit: min / L). From Figure 44 As can be seen, with the continuous increase in gas flow rate, the performance of the test case is superior to that of the comparative example. Figure 44It can also be seen that when the covering area is small, there is no significant difference in airflow resistance between the test case and the comparative example. However, as the covering area increases (e.g., due to larger user fingers or incorrect operation), the airflow resistance of the test case is significantly lower than that of the comparative example. In other words, the test case exhibits excellent airflow performance, especially for large-area coverings. This is because, once the covering area of ​​the comparative example is large, it will largely or completely cover the opening facing the V direction, relying only on some narrow gaps for air to enter. In contrast, the air entry structure of the test case uses a ring-shaped hole design. Even if the covering area increases, since the covering simulates a finger, which is slender, when it covers the proximal end face, the main opening of the hole will inevitably remain in the ring, providing sufficient space for air to flow in.

[0109] As described in the previous embodiments, when a user inhales through the inhaler, air enters the inhaler through the air inlet structure described in any of the preceding embodiments. The force holding unit also includes a breathing actuation mechanism housed in the upper housing. Airflow entering the inhaler can enter the breathing actuation mechanism, thereby causing the breathing actuation mechanism to activate the canister.

[0110] In one embodiment, the mechanism for respiratory actuation may include a compression spring 41, a valve assembly (not identified), a retaining ring 45, a diaphragm 46, and a lower cover 47. The compression spring 41, valve assembly, retaining ring 45, diaphragm 46, and lower cover 47 are mounted within the upper housing 40.

[0111] like Figure 5 As shown, the valve assembly includes a valve housing 42, a valve 43, and a valve spring 44. Further, the valve 43 includes a valve blade 430 and a valve seal 431. The valve 43 is rotatably mounted on the valve housing 42, for example, via a connecting pin (not shown) mounted on the valve housing 42. The valve spring 44 is disposed between the valve housing 42 and the diaphragm 46. The valve 43 is biased onto the diaphragm 46 by the valve spring 44, so that the valve seal 431 seals the diaphragm 46 in this biased position. When a user inhales through the suction port 10, air enters through the air inlet structure and flows toward the suction port 10. The airflow exerts a torsional force on the valve blade 430. When the torsional force generated by the airflow is sufficiently large, it causes the valve 43 to rotate.

[0112] In one embodiment, please refer to Figure 5 and Figure 6 , Figure 6The diagram shown illustrates the structure of the diaphragm in one embodiment of this application. As shown, the diaphragm 46 includes a rigid disc 460 and a flexible skirt 461. The rigid disc 460 is connected to the valve housing 42, and the flexible skirt 461 is connected to the rigid disc 460 and sandwiched between the fixing ring 45 and the lower cover 47. In one embodiment, the rigid disc 460 is made of a rigid material, i.e., it is made of a material with a certain strength. An example of the rigid material is acrylonitrile butadiene styrene. The flexible skirt 461 can be made of a flexible material, which can undergo deformation such as elongation under stress. An example of the flexible material is thermoplastic polyurethane. The rigid disk 460 and the flexible skirt 461 can be configured as an integral structure. For example, the diaphragm 46 can be made by multiple injection molding (e.g., double injection molding), first using a rigid material to injection mold the rigid disk 460, and then using a flexible material to injection mold the flexible skirt 461 onto the rigid disk 460, thereby making the rigid disk 460 and the flexible skirt 461 an integral structure.

[0113] In one embodiment, the rigid disc 460 includes a valve port. To facilitate differentiation between the valve port on the rigid disc 460 and the valve port on the flexible skirt 461, in subsequent embodiments, the valve port on the rigid disc 460 is referred to as a first valve port 4600. The first valve port 4600 is located in the central region of the rigid disc 460, and when sealed by the valve 43, a sealing cavity 7 is formed between the diaphragm 46 and the lower cover 47. Furthermore, the rigid disc 460 also includes a baffle 4601. The baffle 4601 prevents air from flowing between the diaphragm 46 and the valve sealing portion 431.

[0114] In one embodiment, the rigid disk 460 further includes a boss 4603 disposed at the center of the rigid disk 460 and an outer wall 4604 disposed on the outer side of the rigid disk 460. The boss 4603 and the outer wall 4604 increase the rigidity of the rigid disk 460. The outer surface of the outer wall 4604 may be further configured to have uneven regions, and the valve housing 42 is coupled to the outer wall 4604 and engages with the uneven regions of the outer surface of the outer wall 4604. To facilitate the positioning of the diaphragm 46, the rigid disk 460 may further include a positioning member 4602. The positioning member 4602 can engage with the valve housing 42 so that the diaphragm 46 is positioned at the engaged position of the valve housing 42.

[0115] like Figure 5As shown, the flexible skirt 461 is disposed between the fixing ring 45 and the lower cover 47 and connected to the rigid disc 460. When the fixing ring 45 moves toward the distal end, the flexible skirt 461 is deformed by the fixing ring 45 (for example, from a wrinkled state to an unfolded state), which can increase the volume of the sealing cavity 7 so that the sealing cavity 7 is under negative pressure when sealed, thereby increasing the sealing performance between the diaphragm 46 and the valve sealing part 431.

[0116] In one embodiment, such as Figure 5 and Figure 6 As shown, the flexible skirt 461 includes a flexible annular curved portion 4610, a flexible connecting ring 4611, and a second valve hole 4612. The flexible skirt 461 is disposed between the fixing ring 45 and the lower cover 47 via the flexible connecting portion 4611. The flexible annular curved portion 4610 is located in the recessed area of ​​the lower cover 47. The second valve hole 4612 is formed on the flexible skirt 461 and communicates with the first valve hole 4600.

[0117] Please continue reading. Figure 7 and combined Figure 2 , Figure 7 The diagram shows a structural schematic of the support in one embodiment of this application. As shown, the support 3 in the inhaler is used to connect to the force-holding unit 4 to position the force-holding unit 4, and can also be used to transmit the force between the other components connected to it and the force-holding unit 4. Specifically, the support 3 can be sleeved on the canister 2 and connected to the lower cover 47.

[0118] In one embodiment, the bracket 3 includes a bracket body 32, a drive rod 30, and a support rod 31. The bracket body 32 is generally ring-shaped and can be fitted onto the tank 2. The support rods 31 are disposed on opposite sides at the distal end of the bracket body 32. When the dust cover 6 is closed, the support rods 31 are supported by the dust cover 6 to be held in a proximal state, thereby positioning the force holding unit 4 under the action of the bracket body 32 to keep the force holding unit in a proximal state. Further, the support rod 31 in contact with the dust cover 6 is provided with a reinforcing part to enhance the rigidity of the support rod 31. It should be noted that the force holding unit 4 being held in a proximal state means that the lower cover 47 and the fixing ring 45 in the force holding unit 4 are in a proximal state, the compression spring 41 is in a compressed state, and the valve 43 seals the diaphragm 46. Although Figure 7 In the illustrated embodiment, there are two support rods 31, but in other embodiments, there may be more than two support rods 31. The drive rod 30 is located at the distal end of the support body 32, combined with... Figure 4As shown, the drive rod 30 can extend through the hole structure provided on the counting space 11 to drive the dose counter to count.

[0119] The following combination Figures 8 to 11 The different states of the inhaler, and the interactions between the force-holding unit, the support, and the canister in each state, are explained. Figure 8 This is a schematic diagram showing the inhaler in a dormant state in one embodiment of this application. Figure 9 Displayed as Figure 8 The diagram shows the force-holding unit in a dormant state. Figure 10 This is a schematic diagram showing the inhaler in a ready state in one embodiment of this application. Figure 11 This diagram shows the force-holding unit of the inhaler in the activated state.

[0120] When the inhaler is in a dormant state, that is, when the dust cover 6 is closed, the protrusion 60 on the dust cover 6 cooperates with the support rod 31 of the bracket to lock the bracket 3 in a proximal state. The bracket 3 in the proximal state will abut against the force holding unit, so that the force holding unit is in a proximal state. Specifically, the bracket 3 abuts against the lower cover 47 of the force holding unit, and further fixes the compression spring 41 by the retaining ring 45. At this time, there is an axial gap 8 between the lower cover 47 and the canister 2. The compression spring 41 is in a fully compressed state (the fully compressed state refers to the maximum degree of compression of the compression spring during the entire operation of the inhaler) to store energy, and the valve 43 seals the first valve hole 4600 of the diaphragm 46 to form a sealed cavity 7 between the diaphragm 46 and the lower cover 47.

[0121] The inhaler transitions from a dormant state to a ready state, corresponding to the opening of the dust cover 6. The support 3 moves distally (this action provides space for the compression spring 41 to release energy). The compression spring 41 releases energy to push the lower cover 47 and the retaining ring 45 distally. Consequently, the flexible skirt 461 of the diaphragm 46 unfolds from its pleated state under the clamping of the lower cover 47 and the retaining ring 45. Furthermore, the annular curved portion 4610 of the flexible skirt 461 is unfolded. This increases the volume of the sealing cavity 7 between the lower cover 47 and the diaphragm 46. When the sealing cavity 7 is sealed, it is under negative pressure, which further enhances the seal between the diaphragm 46 and the valve sealing portion 431. The negative pressure within the sealing cavity 7 also generates a proximal force to counteract the distal force generated by the compression spring 41. The movement of the compression spring 41 toward the distal end stops when its force toward the distal end balances with its force toward the proximal end (the force toward the proximal end is mainly the force generated by the sealed cavity 7). It should be noted that the movement of the bracket 3 toward the distal end when the dust cover 6 is opened means that the bracket 3 has a movement toward the distal end when the dust cover 6 is open, not that the bracket 3 necessarily only has a movement toward the distal end. Considering the coordination between structural designs, the bracket 3 is also allowed to have a movement toward the proximal end during the opening of the dust cover 6, as long as the amount of movement toward the distal end of the bracket 3 when the dust cover 3 is opened is greater than the amount of movement toward the proximal end.

[0122] It should be noted that the force balance of the compression spring 41 described in the above embodiments only considers the main forces, and does not take into account the minor forces generated by the interaction between various structures in the inhaler that affect the compression spring 41. For example, in some examples, when the lower cover 47 moves toward the distal end, the lower cover 47 occupies the axial gap 8 between the lower cover 47 and the canister 2 when the dust cover 6 is closed and begins to slightly press against the canister 2, causing the canister 2 to slightly compress its valve stem 22 (this slight compression is insufficient to release the drug solution from the valve stem 22 and does not affect the user's use). At this time, the valve stem 22 will generate a small force toward the proximal end. The exemplified minor force is only one example. It is also possible that the lower cover 47 may just contact the canister 2 without generating a force toward the proximal end, or other minor forces may be generated by the interaction between other structures in the inhaler. Since these minor forces contribute very little to the force balance, in the embodiments of this application, the force balance of the compression spring 41 is described by ignoring these minor effects.

[0123] The inhaler transitions from a ready state to an activated state, corresponding to the user inhaling through the inhalation port 10. At this time, air enters through the air inlet structure and forms an airflow towards the inhalation port 10 within the inhaler. When the torsional force of the airflow acting on the valve vane 430 exceeds the torsional force acting on the valve vane 430 by the valve spring 44 and the sealing cavity 7, the valve 43 rotates, causing the valve sealing part 431 to open the diaphragm 46, allowing air to enter the sealing cavity 7. At this point, the air pressure within the sealing cavity 7 changes from a negative pressure state to atmospheric pressure. Thus, the force exerted by the negative pressure within the sealing cavity 7 towards the proximal end disappears, breaking the force balance in the ready state. Consequently, the compression spring 41 extends further (i.e., further releases energy). As the compression spring 41 extends further, the lower cover 47, the retaining ring 45, and the support 3 move further towards the distal end, causing the canister body 20 to move distally relative to the valve stem 22. Then the valve stem 22 can enter the metering chamber so that the drug solution in the metering chamber is sprayed out from the valve stem 22 in a mist form until the valve stem 22 continues to move to the stop part inside the valve 21, at which point the valve stem 22 stops moving.

[0124] Furthermore, the user can reset the inhaler by closing the dust cover 6. At this time, the support 3 is pushed towards the proximal end by the dust cover 6, which further causes the force holding unit to move towards the proximal end. As a result, the flexible skirt 461 of the diaphragm 46 in the force holding unit gradually returns to its original shape and discharges gas from the sealed cavity 7. Then, under the action of the valve spring 44, the valve 43 rotates and continues to seal the diaphragm 46, so that the sealed cavity 7 is in a vacuum state.

[0125] It should be noted that the force-holding unit and the bracket are not limited to those described in this application. Figures 1 to 7 The structure of the embodiment shown can also be made of other mechanical structures. For example, as long as it can ensure that the force holding unit can activate the canister 2 when the user inhales, so that the valve stem 22 can enter the metering chamber (i.e., the drug solution in the metering chamber can be sprayed out from the valve stem 22 in a mist).

[0126] like Figure 2 As shown, the dose counter 5 is disposed within the main housing 1 and further disposed within the counting space 11 of the main housing 1, for counting the number of uses of the inhaler. It should be understood that the dose counter 5 is disposed within... Figure 1 and Figure 2The respiratory-actuated inhaler shown is merely an exemplary illustration. In other embodiments, the dose counter 5 may also be configured in any inhaler that is not respiratory-actuated, such as manually actuated, actuated by means of an additional actuation mechanism, or actuated by electronic control. The following embodiments are based on the working principle of the dose counter 5 configured in a respiratory-driven inhaler and are not intended to limit the inhalers to which the dose counter 5 is applicable.

[0127] Please see Figure 12 and Figure 13 The following are schematic diagrams of the dose counter structure in different embodiments of this application, such as... Figure 12 and Figure 13 As shown, the dose counter 5 includes an actuation mechanism 50 and a counting component 51. The actuation mechanism 50 moves distally when driven, and the counting component 51 counts the number of uses of the inhaler based on the distal movement of the actuation mechanism 50, and indicates the number of uses of the inhaler with a visual numerical representation. The actuation mechanism 50 can be driven in response to different driving operations depending on the actuation mechanism of the inhaler to which it is applied. For example, the actuation mechanism 50 can be driven distally in response to user inhalation, manual triggering, action mechanism triggering, or electrical triggering by an electronic control device.

[0128] In one embodiment, the actuation mechanism 50 is configured to be driven toward a distal end in response to a user's inhalation. The main housing, canister, force-holding unit, and support of the inhaler are arranged as follows: Figures 1 to 11 In any embodiment of the example structure shown, the actuation mechanism 50 is further driven to move toward the distal end by the bracket, or the actuation mechanism 50 is part of the bracket and moves toward the distal end along with the bracket when the bracket is driven. In other examples, the actuation mechanism 50 may also be driven to move toward the distal end by a structure that can be linked with the above structure or unit. This application does not limit this.

[0129] In one embodiment, such as Figure 12 As shown, the actuation mechanism 50 includes a drive member 500 and a return spring 501. For example... Figure 7 When the illustrated bracket 3 (specifically, the drive rod 30 of bracket 3) moves distally, it drives the drive member 500 to move distally and compresses the return spring 501. When the bracket 3 moves proximally, the return spring 501 extends, causing the drive member 500 to move proximally. Further, please refer to... Figure 14 This application is shown as being in Figure 12The schematic diagram of the actuator moving toward the distal end in the embodiment shown is shown in the figure. The driving member 500 includes a driving claw 5000 for driving the counting component 51. When the actuator 50 moves toward the distal end, it can contact the counting component 51 to drive the counting component 51.

[0130] In one embodiment, such as Figure 13 As shown, the actuation mechanism 50 includes a drive member 500, which is configured as a claw formed on the support 3, and further, the claw is formed on the drive rod 32 of the support 3. When driven (i.e., when the support 3 is driven), the drive member 500 moves toward the distal end, so that the drive member 500 can contact the counting component 51 to drive the counting component.

[0131] In one embodiment, such as Figure 12 and Figure 13 As shown, the counting component 51 includes a first counting unit 510 and a second counting unit 511. The first counting unit 510 is driven by the actuation mechanism 50 to count a first set of numbers when the actuation mechanism 50 moves toward the distal end, and the second counting unit 511 is driven to count a second set of numbers when the first counting unit 510 has counted a preset number of times. The first counting unit 510 and the second counting unit 511 cooperate to visually indicate the number of times the inhaler has been used.

[0132] The visualized numbers can be Arabic numerals, or they can be represented using Chinese characters or English letters, etc. This application does not limit the language used to represent the numbers. In the following embodiments of this application, Arabic numerals are used as an example for illustration.

[0133] The preset number of times is related to the carry-over timing between the first group of numbers and the second group of numbers. In one embodiment, the preset number of times includes the number of times determined based on the carry-over relationship between the first group of numbers and the second group of numbers in the visualized numbers. It can reflect the timing of the carry-over from the first group of numbers to the second group of numbers for the nth time (n is an integer greater than 1). Taking the first group of numbers and the second group of numbers as a decimal relationship as an example (in this example, the first counting unit can also be called the units digit counting unit, and the second counting unit can also be called the tens digit counting unit), the preset number of times is set to a positive integer multiple of 10 (i.e., 10, 20, 30...) plus the count of the first carry-over. Taking the first carry-over as the first count as an example, the second counting unit can be driven to count when the first counting unit performs a count of a positive integer multiple of 10 plus 1. In one embodiment, the preset number of times further includes the number of counts corresponding to the first carry determined based on the initial value of the visualized number. Specifically, based on the initial value and the carry relationship between the two sets of numbers, the timing of the first carry from the first set of numbers to the second set of numbers can be determined. Taking the initial value of the visualized number as 120 as an example, the preset number of times also includes the first count, that is, the second counting unit will be driven to count when the first counting unit performs the first count; taking the initial value of the visualized number as 111 as an example, the preset number of times also includes the second count, that is, the second counting unit will be driven to count when the first counting unit performs the second count; taking the initial value of the visualized number as 112 as an example, the preset number of times also includes the third count, that is, the second counting unit will be driven to count when the first counting unit performs the third count.

[0134] In one embodiment, the counting component 51 can be used to indicate the remaining number of uses in the inhaler or the number of uses already made. For example, if the current counting component 51 displays the number 99, after the user uses the device once, if the counting component 51 indicates the remaining number of uses, then the counting component 51 displays 98; if the counting component 51 indicates the number of uses already made, then the counting component 51 displays 100.

[0135] In an embodiment where the counting component 51 indicates the number of times the device has been used, the visual number presented by the counting component is displayed as a positive number. In this embodiment, in the initial state of the inhaler, the number indicated by the first counting unit and the second counting unit indicates that the inhaler has not been used since it left the factory, for example, indicating a number of 0. After each use, the counting component 51 counts once and increases the number by one, for example, indicating a number of 1.

[0136] In an embodiment where the counting component 51 indicates the remaining number of uses, the visual number presented by the counting component is displayed in a countdown manner. In this embodiment, in the initial state of the inhaler, the number indicated by the first counting unit and the second counting unit in conjunction represents the total number of uses of the inhaler in the initial state (i.e., the total number of uses at the time of manufacture), such as... Figure 13 As shown, the inhaler's initial total usage count is displayed as 120. After each use, the counter component 51 counts once, decreasing the number by one, displaying 119. This way, the user sees the remaining amount of the inhaler each time, helping them to understand the inhaler's remaining lifespan and prepare accordingly. Of course, Figure 19 The display only shows the number of uses after the inhaler leaves the factory. It can also indicate the number of uses tested during the inhaler's production phase, still based on the initial state. Figure 13 Taking the displayed number as an example, after testing during the production phase, the counting component displays the number 120. Therefore, the counting component needs to display a number larger than 120 so that the use of the production phase test prompts the counting component to count down to 120. For example, during the production phase, the counting component displays the number 130, which can be used 10 times for testing. In the 10 tests, the first counting unit and the second counting unit cooperate to display integers from 129 to 120 in sequence (i.e., displaying 129, 128, 127, 126, 125, 124, 123, 122, 121, 120 in sequence). These integers and the starting value 130 are used to indicate the number of times the production phase test is performed.

[0137] In subsequent embodiments, the example shown is that the visualized numbers are displayed in a reciprocal manner, which should not be construed as a limitation of this application.

[0138] The number of digits in the first and second sets of numbers is related to the total number of uses of the inhaler. For example, if the total number of uses is a two-digit number (e.g., 99), the combined number of digits in the first and second sets must be at least two digits. In this example, the first set of numbers can be set to one digit, and the second set can be set to one digit. Similarly, if the total number of uses is a three-digit number (e.g., 120), the combined number of digits in the first and second sets must be at least three digits. In this example, the first set of numbers can be set to one digit, and the second set can be set to two digits. The first and second counting units work together to indicate the number of uses in the inhaler using a three-digit number. Specifically, if the total number of uses is 120, the first set of numbers includes ten one-digit numbers from 0 to 9. The second group of numbers includes at least 13 numbers from 0 to 12. Thus, the first group of numbers and the second group of numbers can be combined to display one, two, or three digits. In other words, the first group of numbers and the second group of numbers can be combined to display at least all integer digits from 0 to 120, that is, at least 0, 1, 2, 3, ..., 119, 120.

[0139] The total number of uses for the inhaler can be set to include only the total number of uses in the initial state, or it can be set to include both the total number of uses during the production phase testing and the total number of uses in the initial state. For example, if the total number of uses for the inhaler is configured to be 120 uses in the initial state, the second set of numbers can include numbers from 0 to 12. This, combined with the first set of numbers, can display 120, 119, ..., 3, 2, 1, 0, indicating the number of uses after the inhaler leaves the factory. Alternatively, if the total number of uses for the inhaler also includes 10 uses during the production phase testing, then the second set of numbers needs to include more numbers than 12 for display during the production phase. That is, the second set of numbers includes numbers from 0 to 13, and combined with the first set of numbers, can display 130, 129, ..., 120, 119, ..., 3, 2, 1, 0. 130, 129, ..., 121, 120 can be displayed during the production phase of the inhaler; after leaving the factory, the inhaler displays 120, 119, ..., 3, 2, 1, 0. Of course, in other examples, the production testing phase may not require configuring a numerical display; that is, 13 may not be set, and only a blank space may be reserved. The same understanding applies when the total number of uses of the inhaler is a two-digit number, and it can be set in a similar way, which will not be elaborated upon here.

[0140] In one embodiment, a propulsion unit can be provided so that when the first counting unit 510 performs a preset number of counts, it can drive the second counting unit to perform a second set of digit counts. For example... Figure 12 and Figure 13As shown, the counting component 51 further includes a propulsion unit 512 that engages with the second counting unit 511. When the first counting unit 510 performs a preset number of counts, it engages with the propulsion unit 512 to drive the second counting unit 511 to count. In other words, the first counting unit 510 engages with the propulsion unit 512, and after the propulsion unit 512 engages with the second counting unit 511, the movement of the first counting unit 510 can drive the movement of the second counting unit 511. Here, "engagement" refers to a contacting and mating mechanism that creates a linkage, such as locking or meshing.

[0141] In one embodiment, please refer to Figure 15 The figure shows a schematic diagram of the propulsion unit in one embodiment of this application. As shown, the propulsion unit 512 includes a first gear 5120 and a second gear 5121 that have a linkage relationship. Figure 12 and Figure 13 As shown, the first gear 5120 is driven by the first counting unit 510 to rotate the second gear 5121 when the first counting unit 510 counts a preset number of times. The second gear 5121 engages with the second counting unit 511 to cause the second counting unit 511 to count when rotating. In one example, the first gear 5120 and the second gear 5121 can be fixedly connected by a connecting rod 5122. Thus, when the first gear 5120 is driven to rotate by the first counting unit 510, the connecting rod 5122 will further drive the second gear 5121 to rotate, thereby driving the second counting unit 511 to count.

[0142] In one embodiment, please refer to Figure 16The figure shows a schematic diagram of the split structure of the first and second counting units in one embodiment of this application. As shown, the first counting unit 510 includes a first counting wheel 5101 with a first set of numbers marked on its circumference, and the second counting unit 511 includes a second counting wheel 5110 with a second set of numbers marked on its circumference. The first counting wheel 5101 and the second counting wheel 5110 are arranged side-by-side. When driven, the first and second counting wheels rotate to display their respective numbers in a display window, indicating the number of times the inhaler has been used by combining the two sets of numbers. For example, each time the inhaler is used, the first counting wheel 5101 rotates once to change the number and displays the changed number in the display window. After the first counting wheel 5101 rotates a preset number of times, the second counting wheel 5110 rotates once to change the number and displays the changed number in the display window. The number formed by combining the two sets of numbers indicates the number of uses. The display window is a window on the inhaler that allows light to enter, so that the user can observe the numbers displayed on the counting wheels through the display window.

[0143] It should be noted that although the numbers are marked on the counting wheel in this application, it is not limited thereto. In other embodiments, the first set of numbers and the second set of numbers may also be set on a belt that can be unwound with the reel.

[0144] In one embodiment, such as Figure 16 As shown, the second counting unit 511, in addition to the second counting wheel 5110, also includes a second actuating gear 5111 for interaction with the propulsion unit. The second actuating gear 5111 has a plurality of teeth spaced apart in a circumferential direction. The propulsion unit drives one tooth of the second actuating gear 5111 to move, thereby causing the second counting wheel 5110 to rotate by one count. Specifically, the second counting wheel 5110 and the second actuating gear 5111 are linked, and the two can be directly or indirectly connected, or they can be formed by an integral structure.

[0145] The number of teeth on the second actuating gear 5111 is related to the number of digits in the second set of numbers, and must be no less than the number of digits in the second set of numbers. For example, if the second set of numbers includes the 13 digits 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, and 12, then the number of teeth on the second actuating gear 5111 should be no less than 13. For example, the number of teeth on the second actuating gear 5111 is 14. Furthermore, if the second set of numbers includes the 14 digits 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, and 13, then the number of teeth on the second actuating gear 5111 should be no less than 14.

[0146] In one embodiment, such as Figure 16 As shown, the first counting unit 510 further includes a shaft element 5100 distributed along the central axis of the first counting wheel 5101 and fixedly connected to the first counting wheel 5101. The second counting wheel 5110 is sleeved on the shaft element 5100 and rotatably supported by the shaft element 5100. Furthermore, when the second counting unit 511 includes a second actuating gear 5111, the second actuating gear 5111 can also be sleeved on the shaft element 5100.

[0147] Please see Figure 17 and Figure 18 The following are schematic diagrams of the structure of the first counting unit in different embodiments, such as... Figure 17 and Figure 18 As shown, the first counting unit 510 further includes a first actuating gear 5102 fixed to the shaft element 5100, which has a plurality of teeth spaced apart in the circumferential direction. The actuating mechanism moves against one of the teeth toward the distal end to cause the first counting wheel 5101 to rotate one count. Specifically, please refer to... Figure 17 and combined Figure 14 The driving pawl 5000 of the actuation mechanism 50 abuts against one of the teeth of the first actuation gear 5102, causing the first counting wheel 5101 to rotate one count when the driving pawl 5000 moves toward the distal end. See also... Figure 18 and combined Figure 13 The driving member 500 of the actuation mechanism 50 abuts against one of the teeth of the first actuation gear 5102, causing the first counting wheel 5101 to rotate by one count when the driving member 500 moves toward the distal end. In one embodiment, when the first group of numbers in the first counting unit 510 is set to 1 digit, the first group of numbers marked on the first counting wheel includes ten integers: 0, 1, 2, 3, 4, 5, 6, 7, 8, and 9. The gear has 10 teeth corresponding to the ten integers, with each tooth corresponding to one number in the first group of numbers. That is, when a tooth is driven, the number corresponding to that tooth will be rotated to a position that can be observed by the user, such as rotating to the display window described below.

[0148] In one embodiment, such as Figure 17 and Figure 18 As shown, the first counting unit 510 further includes a single-tooth element 5103, which is fixed to the shaft element 5100 or the first actuating gear 5102 to rotate with the shaft element 5100 or the first actuating gear 5102. When the first counting unit 510 performs a preset number of counts, the single-tooth element 5103 rotates in contact with the propulsion unit to drive the second counting wheel 5110 to rotate. Figure 12 and Figure 13 In the example shown where the propulsion unit 512 is located on the upper side, the single-tooth element 5103 is located below the first gear 5120 of the propulsion unit 512. It should be noted that, depending on the structure and installation position of the propulsion unit, the single-tooth element 5103 can also be positioned in different locations. For example, if the propulsion unit 512 is located below the first counting unit 510 and the second counting unit 511, then the single-tooth element 5103 can be located above the propulsion unit 512.

[0149] Furthermore, combined Figure 14 and Figure 15 Taking the pusher unit configured as including a first gear 5120 and a second gear 5121 as an example, for Figure 17 and Figure 18 The following example illustrates how the single-tooth element 5103 drives the second counting wheel 5110 to count. Specifically, when the actuation mechanism 50 is driven, it interacts with one tooth of the first actuation gear 5102, causing the first counting wheel 5101 and the single-tooth element 5103 to rotate. This can be understood as the first counting assembly 51 rotating as a whole, with each rotation corresponding to one count by the first counting wheel. Before each preset number of counts, the single-tooth element 5103 moves to a pre-engagement position, as shown... Figure 14 The single-tooth element 5103, in its current state, will rotate with the first actuating gear 5102 through the tooth in the first gear 5120 of the pushing unit 512 that is in the pre-engaged position during the preset count. This will push the tooth away from the preset engagement position, causing the first gear 5120 of the pushing unit 512 to drive the second gear 5121 to rotate once. The second gear 5121 will then drive the second counting wheel 5110 to rotate once. When the single-tooth element 5103 pushes the tooth in the first gear 5120 that is in the pre-engaged position away from the preset engagement position, the next tooth of the first gear 5120 moves to the pre-engaged position to contact the single-tooth element 5130 when it returns to this position for the next count of the second counting wheel.

[0150] Taking the initial state where the counting component displays the number 120 as an example, the preset number of counts includes the first count and counts that are multiples of 10 plus 1, such as the 1st, 11th, 21st, 31st, 41st, 51st, 61st, 71st, 81st, 91st, 101st, 111th, and 121st counts. Before the first count, the single-tooth element 5103 and the first tooth of the first gear 5120 are in a preset engagement position. Thus, when the first count is performed, the single-tooth element 5103 pushes the first tooth to make the pushing unit rotate once, which in turn causes the second counting wheel to rotate once, and the counting component displays the number 119. Subsequently, the second tooth of the first gear 5120 is in a preset engagement position, and the single-tooth element 5103 leaves the preset engagement position. During the 2nd to 10th counts, the single-tooth element 5103 moves once each time, returning to the preset engagement position upon completion of the 10th count. Thus, during the 11th count, the single-tooth element 5103 pushes the second tooth, causing the pushing unit to rotate a second time, which in turn causes the second counting wheel to rotate a second time, and the counting component displays the number 109. This cycle repeats. During the 111th count, the single-tooth element 5103 pushes the 12th tooth, causing the pushing unit to rotate a 12th time, which in turn causes the second counting wheel to rotate a 12th time, and the counting component displays the number 9. During the 121st count, the counting component displays the number 0, indicating that the maximum count has been exceeded. In some embodiments, such as those including subsequent embodiments with signal elements, the single-tooth element 5103 pushes the 13th tooth, causing the pushing unit to rotate a 13th time, which in turn causes the second counting wheel to rotate a 13th time, allowing the signal element to obscure the display of the counting component.

[0151] It should be understood that the pre-engagement position refers to the position corresponding to which the single-tooth element and the propulsion unit can generate transmission motion. It does not represent a fixed position point, but rather indicates that in the pre-engagement position, the continued movement of the single-tooth element can contact and drive the movement of the propulsion unit. Furthermore, Figure 14 Therefore, the actuation mechanism 50 is configured as follows: Figure 12 The following explanation uses the structure shown as an example to illustrate how the single-tooth element 5103 drives the second counting wheel 5110 to count. The actuation mechanism 50 adopts the following... Figure 13 The structure shown illustrates the principle of the single-tooth element 5103 driving the second counting wheel 5110 for counting. Figure 14 The same applies, so I won't repeat it here.

[0152] To prevent further counting by the dose counter after the inhaler has reached its maximum number of uses, in one embodiment, a stop structure is provided on the first gear of the propulsion unit. When the maximum number of counts is exceeded, the single-tooth element pushes the first gear to rotate the stop structure to the preset engagement position to stop the single-tooth element from driving the propulsion unit. Alternatively, it can be described as causing the propulsion unit to lose contact with the single-tooth element.

[0153] Please see Figure 19 The image shown is a schematic diagram of the propulsion unit in one embodiment of this application. Figure 20 This application is displayed as being in Figure 19 The diagram showing the operational state of the stopping structure in the propulsion unit is as follows: Figure 19 and Figure 20 As shown, the first gear 5120 of the propulsion unit 512 is equipped with a stop structure 5123. When the count exceeds the maximum number of uses (i.e., the count corresponding to the maximum number of uses), the stop structure 5123 rotates to the pre-engagement position (as shown). Figure 20 The states shown in (b) and (c) are such that the first gear 5120 cannot contact the single-tooth element 5103, thereby stopping the driving action of the single-tooth element 5103 on the push unit 512 and preventing the counting of the second counting wheel. In a specific example, the stopping structure 5123 is configured as a missing tooth (or recess) on the first gear 5120, which is located after the last tooth 51200 of the first gear 5120. The last tooth 51200 corresponds to the tooth that is driven to rotate by the single-tooth element 5103 when the maximum number of uses has been exceeded. Before the counting exceeds the maximum number of uses, the single-tooth element 5103 and the first gear 5120 are in the following position. Figure 20 In the state shown in (a), the last tooth 51200 and the single tooth element 5103 are in the pre-engaged position. Therefore, during the final count, the single tooth element 5103 pushes the last tooth 51200 to rotate, causing the second counting wheel to rotate once. This causes the last tooth 51200 to leave the preset engagement position, and the stopping structure 5123 reaches the preset engagement position (as shown in the diagram). Figure 20 In the state shown in Figure (b), the stopping structure 5123 reaches the preset engagement position, which prevents the first gear 5120 from contacting the single tooth element 5103, even if the single tooth element 5123 moves back to the pre-engagement position (as shown in Figure (b)). Figure 20 When the state presented in (c) is to be used for the next count, the single tooth element 5123 can only pass through the stop structure 5123 without contact.

[0154] Continuing with the example of the counting component displaying the number 120 in the initial state, the preset number of times includes the 1st, 11th, 21st, 31st, 41st, 51st, 61st, 71st, 81st, 91st, 101st, 111th, and 121st times. Figure 19 The push unit 512 shown is described below. The count that exceeds the maximum number of uses corresponds to the aforementioned 121st count. At this time, the single tooth element 5103 pushes the first gear 5120 to make the stop structure 5123 be in the pre-engagement position. Therefore, when the count continues after the 121st count, the single tooth element 5123 will no longer be able to contact the push unit 512 and will no longer have a driving effect on the push unit 512.

[0155] It should be noted beforehand that in embodiments where the counter also includes the signal elements described later, such as Figure 19 and Figure 20 The push unit shown enables the second counting unit to rotate once when counting exceeds the maximum number of uses, so that the signal element obscures the display of the counting component (see the following embodiments including the signal element for details, which will not be repeated here). Therefore, even if the first counting unit is rotating or moving, it will not be visible to the user.

[0156] In one implementation, the actuation mechanism 50 moves toward the distal end such that when the counting component 51 counts, the corresponding number on the first counting wheel 5101 is offset from the correct display position in the display window. For example, see [link to relevant documentation]. Figure 12 , Figure 13 and 21 , Figure 21 The figure shows a schematic diagram of the counting component displaying a number offset from the display window in one embodiment of this application. As shown, when the drive member 500 of the actuation mechanism 50 moves toward the distal end, it drives the first counting wheel 5101 to rotate clockwise. After the movement stops, the number on the first counting wheel 5101 (e.g., ...) is displayed. Figure 21 The number 9 in the display window 56 is offset from the center position C.

[0157] When the actuation mechanism 50 moves towards the proximal end to reset, it causes the first counting wheel 5101 to rotate in the opposite direction of counting, so that the corresponding number on the first counting wheel 5101 is displayed in the correct position in the display window. For example, see [link to relevant documentation]. Figures 21 to 23 and combined Figure 8 and Figure 12 , Figure 22 This application is displayed as being in Figure 12 The illustrated embodiment shows a schematic diagram of the actuator moving towards the proximal end. Figure 23This diagram illustrates how, in one embodiment of this application, the counting component correctly displays the numbers in the display window. After the user inhales the medication once, the dust cover 6 is closed. As the dust cover 6 rotates to the closed position, the protrusion 60 of the dust cover 6 supports the bracket 3, thereby causing the drive mechanism 500 of the actuation mechanism 50 to move proximally under the action of the return spring 501. When the actuation mechanism 50 moves proximally, it causes the first counting wheel 5101 to rotate in the opposite direction to the counting direction (e.g., counterclockwise), so that the numbers on the first counting wheel 5101 are displayed in the correct position in the display window (i.e., the center of the display window). Furthermore, when the actuation mechanism 50 moves proximally, its drive pawl 5000 deforms towards the actuation mechanism 50 to pass over the next tooth on the first actuation gear 5102 (the tooth adjacent to the currently engaged tooth and close to the proximal end) and engage with the next tooth. When the actuation mechanism 50 moves distally again, the drive pawl 5000 can continue to drive the first counting wheel 5101 to rotate through the tooth it engages with. Presented as Figure 21 and Figure 23 As shown, when the actuation mechanism 50 moves toward the proximal end, the drive pawl 5000 engages with the teeth on the first actuation gear 5102 and drives the first counting wheel 5101 to rotate clockwise. After the actuation mechanism 50 stops moving, the number 9 on the first counting wheel 5101 is offset from the center position of the display window. When the actuation mechanism 50 moves toward the proximal end, the drive pawl 5000 will disengage from the currently engaged tooth and engage with the next tooth, so that the number 9 on the first counting wheel 5101 is displayed in the correct position in the display window.

[0158] It should be understood that, Figure 22 Therefore, the actuation mechanism 50 is configured as follows: Figure 12 Taking the structure shown as an example, the reset process ensures that the numbers are correctly displayed in the display window 56. The actuation mechanism 50 employs, for instance... Figure 13 The structure shown allows the numbers to be displayed correctly in display window 56. Figure 12 Similar, the only difference is that Figure 13 The actuation mechanism 50 does not require a return spring for reset. Specifically, when the user closes the dust cover 6 after one medication inhalation, as the dust cover 6 rotates to the closed position, the protrusion 60 of the dust cover 6 supports the bracket 3. Figure 13 The drive element 500 included in the actuation mechanism 50 is formed on the support 3 and can move proximally along with the support 3. During this process, the drive element 500 moves in a manner similar to... Figure 22 The process shown and described enables the numbers to be displayed correctly in display window 56.

[0159] It should be noted that after the actuation mechanism moves towards the distal end, if the first counting unit achieves a preset number of counts, then after the second counting wheel 5110 is driven, the number on the second counting wheel 5110 will also shift to the center position of the display window. Upon reset, the number on the second counting wheel 5110 can also be displayed in the correct position in the display window.

[0160] In one embodiment, such as Figure 12 and Figure 13 As shown, the counting component 51 further includes a bottom frame 513 for configuring the first counting unit 510 and the second counting unit 511. See also... Figure 24 The diagram shows a structural schematic of the counting component in one embodiment of this application from a certain perspective. The bottom frame 513 may be provided with a first positioning claw 5130 corresponding to a first counting unit and a second positioning claw 5131 corresponding to a second counting unit. In one example, the first positioning claw 5130 and the second positioning claw 5131 are used to position the first counting unit 510 and the second counting unit 511 respectively, to ensure that the numbers on the first counting unit 510 and the second counting unit 511 are displayed at the center position of the display window.

[0161] In this configuration, the first positioning claw 5130 or the second positioning claw 5131 can prevent the counter-rotation of the counting unit by engaging, thereby ensuring the correct display of the numbers. In some embodiments, the first positioning claw 5130 can be engaged with, for example,... Figure 17 or Figure 18 The teeth on the first actuating gear 5102 of the first counting unit 510 shown engage to prevent the first actuating gear 5102 from continuing to rotate counterclockwise when it rotates counterclockwise. Similarly, the second positioning claw 5131 can engage with the teeth on the first actuating gear 5102 as shown in the figure. Figure 16 The teeth on the second actuation gear 5111 of the second counting unit 511 shown engage to abut against the teeth on the second actuation gear 5111 when the second actuation gear 5111 rotates counterclockwise, thereby preventing the second actuation gear 5111 from continuing to rotate counterclockwise.

[0162] To meet the requirements of space saving, rational layout, and compact structure, in one embodiment, such as Figure 18 As shown, the first counting unit 510 may further include a first stop gear 5104, and the first positioning claw 5130 is engaged with... Figure 18The first stop gear 5104 shown engages to prevent the first counting unit 510 from rotating in the reverse direction. The first stop gear 5104 of the first counting unit 510 corresponds to the first actuating gear 5102; that is, the teeth of the first stop gear 5104 correspond to the numbers on the first counting wheel 5101. In one embodiment, as shown... Figure 16 The second counting unit 511 may further include a second stop gear 5112, and the second positioning claw 5131 is connected to the second stop gear 5112 via a stop gear 5112. Figure 16 The second stop gear 5112 shown cooperates to prevent the reverse rotation of the second counting unit 511. The second stop gear 5112 of the second counting unit 511 has a corresponding relationship with the second actuating gear 5111. That is, the teeth of the second stop gear 5112 correspond to the numbers on the second counting wheel 5110.

[0163] Specifically, the first counting unit is configured as follows: Figure 18 Taking the first stop gear 5104 as an example, when the first counting wheel 5101 rotates clockwise, one tooth on the first stop gear 5104 of the first counting unit can pass over the first positioning pawl 5130. When the actuation mechanism 50 stops moving, the corresponding number on the first stop gear 5104 shifts to the correct display position in the display window, and the next tooth contacts the distal surface of the first positioning pawl 5130. For example, when the actuation mechanism 50 stops moving, the tooth on the first stop gear 5104 corresponding to the number 8 passes over the first positioning pawl 5130, while the tooth corresponding to the next number 7 contacts the distal surface of the first positioning pawl 5130 but does not pass over it. During reset, the first stop gear 5104 rotates counterclockwise, causing the tooth corresponding to the number 8 to engage with the first positioning pawl 5130, thus preventing the tooth corresponding to the number 8 from passing over the first positioning pawl 5130 in the reverse direction.

[0164] By setting the first positioning claw 5130 and the second positioning claw 5131, excessive rotation of the counting wheel in the opposite direction to the counting direction can be prevented, ensuring accurate dose display. Furthermore, it also ensures accurate dose display even when the inhaler is dropped or shaken.

[0165] In one embodiment, the bottom frame 513 further includes a mounting portion for securing the shaft element 5100 and / or the connecting rod 5122. The mounting portion is a groove, recess, or similar structure. For example, see [link to relevant documentation]. Figure 22 and combined Figure 12 and Figure 13The bottom frame 513 includes two first mounting portions 5132 symmetrically arranged for fixing the shaft element 5100, and two second mounting portions 5133 symmetrically arranged for fixing the connecting rod 5122.

[0166] In one embodiment, such as Figure 12 and Figure 13 As shown, the dose counter also includes a signal element 514, which is used to move to the display window to notify the user when the number of uses of the inhaler reaches a preset number of uses. Specifically, the signal element 514 is connected to the counting component 51, and is driven by the counting component to appear in the display window to notify the user when the number of uses of the inhaler reaches the preset number of uses. The preset number of uses includes, but is not limited to, less than 0 times, and any number of times in the units or tens place. In the following embodiments, the visual number displayed by the counting component is used to indicate the remaining number of uses in the inhaler as an example.

[0167] In one embodiment, please refer to Figure 25 and Figure 26 The figures show schematic diagrams of the signal element structure in different embodiments of this application. As shown, the signal element 514 includes a body part 5140. When the number of times the inhaler is used reaches a preset number of times, the body part 5140 moves to the display window to prompt the user.

[0168] In one embodiment, the body portion 5140 engages with the second counting unit to move to the display window as the second counting unit counts. Specifically, before moving to the display window, the body portion 5140 is located inside the dose counter (i.e., inaccessible to the user), and can move from the inside to the display window as the second counting unit rotates. See also [example description needed]. Figure 27 The figure shows a schematic diagram of the engagement of a signal element and a second counting wheel in one embodiment of this application. As shown, the body portion 5140 engages with the second counting wheel 5110 of the second counting unit and can rotate with the second counting wheel 5110. For example, the body portion 5140 is provided with a locking portion 5142 to engage with the second counting wheel 5110 by locking the locking portion 5142 onto the second counting wheel 5110. The locking method is, for example, a spline engagement. It should be noted that the second counting unit can also engage with the body portion 5140 in other ways or with other components in the second counting unit (e.g., the second actuating gear 5111), as long as the body portion 5140 can contact the second counting unit and be driven by the second counting unit to move to a display window when the number of uses reaches a preset number of uses.

[0169] In one embodiment, such as Figure 25 and Figure 26 As shown, the body portion 5140 has a stepped outer contour, which can block different digits in the display window in stages. The specific shape of the body portion 5140 is related to the number of stages it needs to block different digits in the display window and the difference between the two digits blocked in adjacent stages. Specifically, the number of steps in the body portion 5140 is the same as the number of stages it needs to block different digits in the display window. For example, when the body portion 5140 needs to block the hundreds, tens, and units digits in three stages, the body portion 5140 has... Figure 25 and Figure 26 The three steps shown are (first step 51400, second step 51401, and third step 51402). When the inhaler is used a first preset number of times, the first step 51400 moves to cover the hundreds digit in the display window as the second counting unit counts. When the inhaler is used a second preset number of times, the second step 51401 moves to cover the display window as the second counting unit counts, together with the first step 51400, to cover the hundreds and tens digits. When the inhaler is used more than the maximum number of times, the third step 51402 moves to the display window as the second counting unit counts, together with the first step 51400 and the second step 51401, to cover all digits.

[0170] Furthermore, the size of each step portion of the main body 5140 is related to the difference between the two digits obscured in the adjacent stages. For example, if the main body 5140 obscures the hundreds digit when the first preset number of uses is 19 and the tens digit when the second preset number of uses is 9, and the difference between the two digits is 10, then the first step portion 51400 of the main body 5140 needs to rotate once with the second counting unit. Correspondingly, the size of the first step portion 51400 must ensure that the hundreds digit is obscured in this one rotation.

[0171] In one example, the first preset usage count is configured to 19 uses remaining, and the second preset usage count is configured to 9 uses remaining. Exceeding the maximum usage count corresponds to counting after 0 uses remaining. That is, when the visual number displayed by the counting component is 19, the main body obscures the hundreds digit; when the visual number displayed by the counting component is 9, the main body obscures the hundreds and tens digits, and the counting component displays 0. If counting continues, the main body will obscure all digits, i.e., the hundreds, tens, and units digits. Specifically, as the counting component counts down from 20 to 19, the first step portion 51400 of the main body 5140 moves to the display window and is positioned corresponding to the hundreds digit. As the counting component counts down from 10 to 9, the second step portion 51401 of the main body 5140 also moves to the display window, occupying the tens digit position to jointly indicate to the user that less than 10 uses remain. As the counting component continues to count down from the number 0, the third step 51402 of the main body 5140 moves to the display window and occupies the unit position to jointly indicate to the user that it can no longer be used, together with the first step 51400 and the second step 51401.

[0172] In one embodiment, please refer to Figure 28 and combined Figure 25 , Figure 28 This application is shown to include Figure 25 The schematic diagram of the counting component in the embodiment of the signal element shown is as follows: Figure 25 and Figure 28 As shown, the signal element 514 further includes a connecting portion 5141 extending from the body portion 5140. The connecting portion 5141 is radially rotatably engaged with the first counting unit 510, allowing the signal element 514 to rotate relative to the first counting unit 510. For example, the connecting portion 5141 is radially engaged with the shaft element 5100 of the first counting unit 510, and the connecting portion 5141 can rotate with the second counting unit relative to the shaft element 5100.

[0173] For further information, please refer to [link / reference]. Figure 25 , Figure 28 ,and Figure 29 ,in Figure 29 This application is displayed as being in Figure 25The schematic diagram of the relative positional relationship between the signal element and the actuation mechanism in the illustrated embodiment is shown in the figure. A stop portion 51410 is formed on the engagement portion 5141. Correspondingly, the actuation mechanism 50 includes a stop claw 5001. When the maximum number of uses of the inhaler is exceeded, the movement of the actuation mechanism 50 toward the distal end causes the second counting unit 511 to rotate the stop portion 51410 above the stop claw 5001, thereby preventing the actuation mechanism 50 from resetting. The stop claw 5001 of the actuation mechanism 50 is misaligned with the driving claw 5000. Specifically, when the counting component displays 0, there is still a remaining dose in the inhaler canister for the user to inhale. When the user continues to inhale, the actuation mechanism 50 drives the first counting unit to rotate, which in turn drives the second counting unit 511 to rotate. For example, the drive claw 5000 of the actuation mechanism 50 drives the first counting unit to rotate (e.g., the number 9 on the first counting unit is located in the display window), which in turn engages with the propulsion unit, causing the propulsion unit to rotate, which in turn causes the propulsion unit to drive the second counting wheel 5110 to rotate. Thus, the signal element 514 rotates with the second counting wheel 5110 to above the stop claw 5001. During the user's closing of the dust cover 6, the actuation mechanism 50 of the inhaler moves proximally; however, the actuation mechanism 50 can only move to the position where its stop claw 5001 abuts against the stop portion 51410. In other words, the stop portion 51410 above the stop claw 5001 prevents the actuation mechanism 50 from moving further proximally, preventing the actuation mechanism 50 from returning to the proximal state before medication dispensing. At this point, the signal element (e.g., the third step 51402 of the signal element) blocks the unit digit (e.g., blocks the number 9 in the display window), causing the entire display window to be blocked by the signal element. Since the position of the actuation mechanism 50 is restricted to driving the tooth in the display window containing the number 8 before it passes the next tooth, the counting component will not continue to rotate when the user continues to inhale. In other words, the stop on the signal element prevents the dose counter from counting further when the maximum number of uses of the inhaler is exceeded.

[0174] In one embodiment, the signal element may be a striking color to more easily attract the user's attention. For example, the signal element could be red, yellow, or similar colors. Alternatively, the color of the signal element may differ significantly from the colors of other visible parts of the dose counter. For instance, if the other visible parts of the dose counter are generally light-colored, the signal element could be a darker color such as black.

[0175] In one embodiment, please refer to Figure 12 and combined Figure 2As shown in the figure, the dose counter 5 further includes a counter housing 52, which accommodates the actuation mechanism 50 and the counting component 51 to mount the dose counter 5 onto the inhaler. The counter housing 52 has grooves, recesses, or similar structures to accommodate the actuation mechanism 50 and the counting component 51. The actuation mechanism 50 and the counting component 51 can be fixed to the counter housing 52 using a snap-fit ​​structure or screw fastening. The counter housing 52 can engage with the main housing 1 to mount the actuation mechanism 50 and the counting component 51 into the counting space 11. In any of the foregoing embodiments, a display window can be provided on the counter housing 52 to display visual numbers to the user.

[0176] Furthermore, such as Figure 12 As shown, a display element 520 is disposed on the display window, and the display element 520 is used to magnify the numbers located in the display window. In one example, the display element 520 includes a magnifying portion 5200 and a blocking portion 5201 extending to both sides from the magnifying portion 5200. The magnifying portion 5200 is located in the middle area of ​​the display window to magnify the numbers in the display window, and the blocking portions 5201 on both sides are located in the upper and lower areas of the display window respectively to block the upper and lower areas. Further, the blocking portions 5201 on the upper and lower sides can also be used to connect with the counter housing 52 to fix the display element 520 to the display window. In one example, as shown... Figure 12 As shown, the display element 520 is configured as a concave structure with a convex surface. The concave structure is recessed in the direction of the convex surface to form a planar area and side areas located on both sides of the planar area. The planar area and the convex surface form the magnifying portion 5200, and the side areas and the convex surface form the blocking portion 5201. Further, the display element 520 can be configured as a transparent material, with the planar area configured as a smooth surface and the side areas configured as rough surfaces. This allows the numbers on the counting component to be presented to the user through the magnifying portion 5200, while the side portions cannot be presented to the user due to the rough surfaces. Of course, it is also possible to configure only the magnifying portion 5200 of the display element 520 as a transparent material, and the blocking portion 5201 as an opaque or semi-transparent material; this application does not impose any limitations on this.

[0177] In one specific embodiment, the dose counter counts as follows: In the initial state of the inhaler, the first and second counting units cooperate to display the number 120, indicating that the total number of uses in the initial state of the inhaler is 120 doses. When the user opens the dust cover 6 of the dose counter, the protrusion 60 of the dust cover 6 releases the support 3, allowing the support 3 to move distally and achieve force balance with the force maintaining unit. Then, when the user inhales through the inhalation port 10 to inhale one dose of the drug solution, the support 3 (e.g., the drive rod 30 of the support 3) moves distally and drives the drive member 500 to move distally. As the drive member 500 moves distally, it drives the first counting wheel 5101 of the first counting unit 510 to rotate, at which time the rotation of the first counting wheel 5101 rotates the number 9 to the correct display position offset from the display window. During this process, the single-tooth element 5103 of the first counting unit 510 rotates to engage with the propulsion unit 512 to drive the second counting wheel 5110 to rotate, so that the second counting wheel 5110 rotates the number 11 to the correct display position offset from the display window. Then, after the user closes the dust cover 6, the bracket 3 moves towards the proximal end, causing the drive member 500 to move towards the proximal end. As the drive member 500 moves towards the proximal end, it drives the first actuating gear 5102 to cause the first counting wheel 5101 to rotate in the opposite direction to the counting direction, and under the drive of the propulsion unit, the second counting wheel 5110 also rotates in the opposite direction to the counting direction. Thus, the numbers on the first counting wheel 5101 and the second counting wheel 5110 can be displayed in the correct position in the display window, i.e., 119 is displayed in the correct position in the display window. Specifically, after the first actuating gear 5102 of the first counting unit and the second actuating gear 5111 of the second counting unit rotate in opposite directions to the counting direction, they can engage with the first positioning claw 5130 and the second positioning claw 5131 respectively to prevent counting errors. Furthermore, using the above counting method, when the number displayed by the counting component is 19, the body 5140 of the signal element is moved to a display window to block the hundreds digit. When the number displayed by the counting component is 9, the body 5140 can be further moved to the tens digit position in the display window. After the number displayed by the counting component is 0, when the user continues to inhale the medication, the first counting unit rotates again, driving the second counting unit to continue rotating. The body 5140 can then be further moved to the units digit position in the display window to completely block the hundreds, tens, and units digits. By setting a signal element, the user's attention can be drawn to how much dosage remains in the inhaler.

[0178] Among them, the driving unit is configured as follows Figure 19 and Figure 20In the embodiment of the structure shown, after the counting component displays the number 0 (i.e., the maximum count has been reached), when the inhaler continues to be driven, the signal element 514 moves with the second counting wheel 5110 to the display window, completely obscuring the hundreds, tens, and units digits in the display window. However, at this time, the stop structure 5130 provided on the push unit 512 is in the pre-engagement position, so that the first counting component 510 no longer drives the second counting component 511, and the signal element remains obscuring the units, tens, and hundreds digits on the display window, preventing the counting component from counting beyond the maximum number of uses and misleading the user.

[0179] Among them, the signal elements are configured as follows Figure 25 In the embodiment of the structure shown, after the counting component displays the number 0, as the user continues to inhale, the signal element 514 rotates with the second counting wheel 5110 to above the stop claw 5001. During the user's closing of the dust cover 6, the actuation mechanism 50 of the inhaler moves proximally; however, the actuation mechanism 50 can only move to the position where its stop claw 5001 abuts against the stop portion 51410. This ensures that the ones, tens, and hundreds digits on the display window are always obscured, preventing errors in the counting component's display and thus avoiding adverse effects on the user.

[0180] In summary, how to count the number of times a user uses the medication is a pressing technical problem. To address this, this application achieves accurate counting of usages by incorporating a matching first and second counting unit into the dose counter, and using these units to visually indicate the number of uses of the inhaler. Furthermore, a signal element is included to alert the user to the remaining dosage in the inhaler. Moreover, a stop on the signal element prevents the drive mechanism from continuing to operate the first and second counting units after the signal element is blocked, thus preventing the dose counter from incorrectly indicating the number of uses.

[0181] The above embodiments are merely illustrative of the inventive essence and beneficial effects of this application, and are not intended to limit this application. Any person skilled in the art can modify or alter the above embodiments without departing from the principles and scope of this application. Therefore, all equivalent modifications or alterations achieved by those skilled in the art without departing from the spirit and technical concept disclosed in this application should still be covered by the claims of this application.

Claims

1. A dose counter characterized in that, A dose counter for an inhaler, the dose counter comprising: an actuation mechanism configured to move distally when actuated; a counting assembly comprising a first counting unit and a second counting unit; the first counting unit is actuated by the actuation mechanism to count a first set of numbers when the actuation mechanism moves distally, and the second counting unit is actuated by the first counting unit to count a second set of numbers when the first counting unit counts a preset number of times, the first counting unit and the second counting unit cooperate to visually indicate the number of uses of the inhaler.

2. Dose counter according to claim 1, characterized in that The first set of numbers is set to one digit, and the second set of numbers is set to two digits, so that the first counting unit and the second counting unit cooperate to indicate the number of uses in the inhaler in three digits.

3. Dose counter according to claim 2, characterized in that In the initial state of the inhaler, the first counting unit and the second counting unit cooperate to display the number 120, indicating that the total number of uses of the inhaler in the initial state is 120.

4. The dose counter of claim 1, wherein, The indicated number of uses of the inhaler includes at least one of the number of uses in the production stage test and the number of uses after leaving the factory.

5. Dose counter according to claim 4, characterized in that The first counting unit and the second counting unit cooperate to sequentially display the integers from 130 to 120 to indicate the number of uses in the production stage test.

6. The dose counter of claim 1, wherein, The counting assembly is used to indicate the number of uses remaining in the inhaler.

7. The dose counter of claim 1, wherein, The counting assembly further comprises a propelling unit engaged with the second counting unit, the first counting unit is engaged with the propelling unit to drive the second counting unit to count by the propelling unit when the first counting unit counts a preset number of times.

8. Dose counter according to claim 7, characterized in that The propelling unit comprises a first gear and a second gear having a linkage relationship; wherein the first gear is driven by the first counting unit to drive the second gear to rotate when the first counting unit counts a preset number of times, and the second gear is engaged with the second counting unit to promote the second counting unit to count when rotating.

9. The dose counter of claim 1, 7, or 8, wherein, The first counting unit comprises a first counting wheel having a first set of numbers marked on the circumferential surface, and the second counting unit comprises a second counting wheel having a second set of numbers marked on the circumferential surface and arranged in parallel with the first counting wheel, the first counting wheel and the second counting wheel respectively present their respective numbers in a display window by rotating when driven, to indicate the number of uses of the inhaler by the combined numbers of the two sets of numbers.

10. Dose counter according to claim 9, characterized in that The first counting unit further comprises shaft elements distributed along the central axis of the first counting wheel, and the second counting wheel is sleeved on the shaft elements to be rotatably supported by the shaft elements.

11. Dose counter according to claim 10, characterized in that The first counting unit further comprises a first actuating gear fixed on the shaft elements, having a plurality of teeth spaced apart in the circumferential direction, and the actuation mechanism abuts against one of the teeth to move distally to make the first counting wheel rotate one count.

12. Dose counter according to claim 11, characterized in that The first set of numbers marked on the first counting wheel comprises ten integer numbers from 0 to 9, and the first actuating gear has 10 teeth corresponding to the ten integer numbers.

13. The dose counter of claim 9 wherein, The second counting unit further comprises a second actuating gear combined with a propelling unit, the second actuating gear having a plurality of teeth distributed in a circumferential direction, the propelling unit moving one tooth of the second actuating gear to rotate the second counting wheel by one count.

14. The dose counter of claim 9, wherein, The first counting unit further comprises a single-tooth element rotating following the first counting wheel, when the first counting unit counts a preset number of times, the single-tooth element rotates in contact with the propelling unit to drive the second counting wheel to rotate.

15. Dose counter according to claim 14, characterized in that The first gear of the propelling unit is provided with a stop structure, when the single-tooth element drives the first gear to rotate the stop structure to a preset engagement position to stop the driving effect of the single-tooth element on the propelling unit when counting more than a maximum number of times.

16. The dose counter of claim 15, wherein, The stop structure is configured as a missing tooth or a recess on the first gear.

17. The dose counter of claim 9, wherein, When the actuating mechanism moves towards a distal end to count the counting elements, the corresponding numbers on the first counting wheel are offset to the correct display positions in the display window; when the actuating mechanism moves towards a proximal end to reset, the first counting wheel rotates in a direction opposite to the counting direction, so that the corresponding numbers on the first counting wheel are displayed in the correct positions in the display window.

18. The dose counter of claim 1, wherein, The counting element further comprises a bottom frame for configuring the first counting unit and the second counting unit, the bottom frame being provided with a first positioning claw corresponding to the first counting unit and a second positioning claw corresponding to the second counting unit.

19. An inhaler characterised in that A dose counter comprising any one of claims 1 to 18.

20. A breath actuated inhaler, characterised in that, A dose counter comprising: a main housing having a suction port at a distal end thereof; a canister storing a medicament solution and being disposed in the main housing in an axial direction; a force maintaining unit attached to the main housing and engaged with the canister to activate the canister in response to inhalation of a user through the suction port; a bracket connected to the force maintaining unit to position the force maintaining unit; a dose counter according to any one of claims 1 to 18, disposed in the main housing to count the number of uses of the inhaler.

21. An inhaler according to claim 20, wherein, The bracket is further connected to the dose counter, and the bracket is configured to drive the dose counter to count when the force maintaining unit moves towards a distal end in response to inhalation of the user.

22. An inhaler according to claim 20, wherein The main housing has a counting space for disposing the dose counter, the counting space being provided with an aperture structure, and the bracket has a driving rod extending through the aperture structure to drive the dose counter to count.

23. An inhaler according to claim 20, wherein An actuating mechanism in the dose counter is formed on the bracket.

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