Portable solid-phase extraction device

Abstract

The utility model provides a portable solid-phase extraction device. The portable solid-phase extraction device comprises a sectional collection part and an extraction part, the extraction part comprises a small solid-phase column and a control valve connected to the small solid-phase column, the segmented collection part comprises an upper fixing plate, a lower fixing plate, a liquid outlet pipe and a liquid collection pipe, a T-shaped groove with an upward opening is formed in the lower fixing plate in the length direction of the lower fixing plate, and the upper fixing plate is a T-shaped block matched with the T-shaped groove; a first through hole matched with the liquid outlet pipe is formed in the middle of the upper fixing plate, the top end of the liquid outlet pipe is connected with the control valve, and the bottom end of the liquid outlet pipe extends into the first through hole; a plurality of second through holes matched with the tops of the liquid collecting pipes are formed in the lower fixing plate in the T-shaped groove at intervals in the length direction of the lower fixing plate, and the tops of the liquid collecting pipes are inserted into the second through holes. The portable solid-phase extraction device disclosed by the utility model is convenient for collecting eluents at different sections in the extraction process, and is convenient to operate and easy to disassemble.

Description

Technical Field

[0001] This utility model belongs to the field of detection technology, specifically relating to a portable solid-phase extraction device. Background Technology

[0002] Solid-phase extraction (SPE) is a commonly used sample pretreatment technique. It utilizes a solid adsorbent to adsorb the target compound from the sample matrix and interfering compounds, followed by elution with an eluent or desorption by heating, achieving the separation and enrichment of the target compound. Compared to traditional liquid-liquid extraction, SPE improves analyte recovery, more effectively separates target compounds from interfering compounds, reduces sample pretreatment steps, and is simple to operate, thus finding wide application in pharmaceuticals, food, environmental, commodity inspection, and chemical industries.

[0003] When using extraction devices, staff must carry samples back to the laboratory for extraction, which is inconvenient and time-consuming. Therefore, designing a portable solid-phase extraction device is essential. Existing technology CN211885508U provides a portable solid-phase extraction device for environmental pollutants. While its modular design facilitates the disassembly and cleaning of the liquid flow pipe connected to the extraction column, replacing the collection tube is cumbersome, and it does not allow for convenient collection of eluent from different stages of the extraction process. Therefore, designing a portable solid-phase extraction device that facilitates segmented collection of eluent remains highly necessary. Utility Model Content

[0004] In view of the above problems, this utility model provides a portable solid phase extraction device.

[0005] To achieve the above objectives, the technical solution of this utility model is as follows: a portable solid-phase extraction device, comprising a segmented collection section and an extraction section disposed above the segmented collection section; wherein, the extraction section comprises a solid column and a control valve connected to the bottom outlet of the solid column;

[0006] The segmented collection section includes an upper fixed plate, a lower fixed plate, a liquid outlet pipe, and several detachable liquid collection pipes. The lower fixed plate has an upward-opening T-shaped groove along its length. The upper fixed plate is a T-shaped block that matches the T-shaped groove. The upper fixed plate and the lower fixed plate are slidably connected. The middle of the upper fixed plate has a first through hole that matches the diameter of the liquid outlet pipe. The top end of the liquid outlet pipe is connected to the control valve, and the bottom end extends into the first through hole. The lower fixed plate in the T-shaped groove has several second through holes that match the top of the liquid collection pipes along its length. The top of the liquid collection pipes is inserted into the second through holes.

[0007] The present invention is further configured such that an air hole is provided on the upper fixing plate near the first through hole, and the horizontal center distance between the first through hole and the air hole is smaller than the radius of the second through hole. This configuration is used to connect the atmosphere and the collection pipe during extraction, facilitating the smooth flow of the eluent.

[0008] The present invention is further configured such that the outer side wall of the top of the liquid collecting pipe is provided with a threaded groove, and the second through hole is a threaded through hole that matches the threaded groove of the outer side wall of the liquid collecting pipe.

[0009] The present invention is further configured such that the length of the upper fixing plate is ≥ twice the farthest distance between the first and last second through holes on the lower fixing plate. This configuration is intended to ensure that when collecting eluent from other sections, the collection tube containing the eluent from the previous section remains sealed, preventing solvent evaporation.

[0010] The present invention is further configured such that the solid phase extraction device includes a fixed base plate, the fixed base plate is detachably connected to the bottom surface of the lower fixed plate by a fixing member, and the fixed base plate is provided with a plurality of positioning grooves for the bottom end of the liquid collection tube to extend into.

[0011] The present invention is further configured such that an elastic element is provided in the positioning groove, and the bottom end of the liquid collecting tube abuts against the elastic element. With this configuration, the liquid collecting tube can be fixed by inserting the top and bottom ends of the liquid collecting tube into the second through hole and the positioning groove, respectively.

[0012] The present invention is further configured such that at least one pair of centrally symmetrical lower positioning holes are provided on the edge of the fixed base plate, and an upper positioning hole is provided on the lower fixed plate corresponding to the lower positioning holes, and a vertical support rod is provided between the lower positioning holes and the upper positioning holes.

[0013] The present invention is further configured such that the solid phase extraction device further includes a liquid inlet section, the liquid inlet section includes at least one liquid addition container and a liquid inlet pipe connected to the liquid addition container, the liquid inlet pipe has at least one liquid inlet, each liquid inlet is connected to a liquid addition container, and a liquid inlet valve is provided near the liquid inlet of the liquid inlet.

[0014] The present invention has the following advantages: the portable solid phase extraction device provided by the present invention facilitates the collection of eluent from different stages during the extraction process, the collection tube is easy to replace, and the extraction efficiency is improved; moreover, the solid phase extraction device has a simple structure, is easy to assemble and operate, and is easy to carry. Attached Figure Description

[0015] Figure 1 This is a front view of the portable solid-phase extraction device described in Example 1.

[0016] Figure 2 This is a structural schematic diagram of the upper fixing plate and the lower fixing plate.

[0017] Figure 3 This is a top view of the lower fixing plate.

[0018] Figure 4 Front view of the portable solid-phase extraction device described in Example 2.

[0019] Figure 5 Top view of the fixed base plate.

[0020] Figure 6 This is a front view of the portable solid-phase extraction device described in Example 3.

[0021] Among them, 100 is the segmented collection section, 110 is the upper fixed plate, 111 is the first through hole, 112 is the vent, 120 is the lower fixed plate, 121 is the T-slot, 122 is the second through hole, 130 is the liquid outlet pipe, and 140 is the liquid collection pipe; 200 is the extraction section, 210 is the solid phase column, and 220 is the control valve; 300 is the fixed base plate, 310 is the positioning groove, 320 is the lower positioning hole, 330 is the elastic element, and 340 is the vertical support rod; 400 is the liquid inlet section, 410 is the liquid addition container, 420 is the liquid inlet pipe, and 421 is the liquid inlet valve. Detailed Implementation

[0022] The specific embodiments of this utility model will be described in further detail below with reference to the accompanying drawings and examples. The following examples are used to illustrate this utility model, but are not intended to limit its scope.

[0023] In the description of this utility model, it should be understood that the terms "center," "length," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," and "outer," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. In this utility model, unless otherwise expressly specified and limited, "upper" or "lower" of the first feature than the second feature may include direct contact between the first and second features, or it may include contact between the first and second features not being in direct contact but through another feature between them.

[0024] Example 1

[0025] refer to Figures 1-3This embodiment provides a portable solid-phase extraction device, including a segmented collection section 100 and an extraction section 200 disposed above the segmented collection section 100; the extraction section 200 includes a solid column 210 and a control valve 220 connected to the liquid outlet of the solid column 210.

[0026] The segmented collection section 100 includes an upper fixing plate 110, a lower fixing plate 120, an outlet pipe 130, and several detachable collection pipes 140. The lower fixing plate 120 has an upward-opening T-shaped groove 121 along its length. The upper fixing plate 110 is a T-shaped block that matches the T-shaped groove 121, and the upper fixing plate 110 and the lower fixing plate 120 are slidably connected. The upper fixing plate 110 has a first through hole 111 in its middle that matches the diameter of the outlet pipe 130. The top end of the outlet pipe 130 is connected to a control valve 220, and its bottom end extends into the first through hole 111. The lower fixing plate 120 within the T-shaped groove 121 has several second through holes 122 spaced along its length that match the top of the collection pipes 140. The top end of the collection pipes 140 is inserted into the second through holes 122.

[0027] In this embodiment, the top outer wall of the liquid collection pipe 140 is provided with a threaded groove, and the second through hole 122 is a threaded through hole that matches the threaded groove on the top outer wall of the liquid collection pipe 140.

[0028] In this embodiment, the upper fixing plate 110 is also provided with an air hole 112 near the first through hole 111. The horizontal center distance between the air hole 112 and the first through hole 111 is smaller than the radius of the second through hole 122. The air hole 112 is used to connect the atmosphere and the liquid collection pipe 140, so that the liquid can flow smoothly down during extraction.

[0029] In this embodiment, the length of the upper fixing plate 110 is greater than or equal to twice the furthest distance between the two farthest second through holes 122 on the lower fixing plate 120; that is, the length of the upper fixing plate 110 must satisfy the condition that when the first through hole 111 on the upper fixing plate 110 and the last second through hole 122 are aligned and connected, the second through hole 122 at the first position is still covered by the upper fixing plate 110. This arrangement ensures that when other eluents are collected in segments by moving the upper fixing plate 110, the collection tube 140 containing the collected eluent remains in a sealed state, preventing solvent evaporation.

[0030] When using the portable solid-phase extraction device described in this embodiment, first screw the collection tube 140 into the second through hole 122 to fix the collection tube. Then, by sliding the upper fixing plate 110, align the first through hole 111 and the vent 112 with the lower second through hole 122 to connect them. Then, add the extraction solvent into the solid-phase column 210 for solid-phase extraction. Open the control valve 220, and the solution flows into the corresponding collection tube 140 through the outlet tube 130. During the extraction process, when different solvents are needed for elution, and different segments of the eluted solution need to be collected in segments, close the control valve 220, and slide the upper fixing plate 110 to align the first through hole 111 and the vent 112 with the other collection tubes again to continue collecting different segments of eluent.

[0031] In summary, the portable solid-phase extraction device provided in this embodiment can achieve segmented collection of eluent through simple operation, and avoids solvent evaporation in the collected collection tube during the collection process; moreover, the solid-phase extraction device has a simple structure, is easy to install and carry.

[0032] Example 2

[0033] refer to Figure 4 and Figure 5 Compared with Embodiment 1, the difference is that the portable solid-phase extraction device described in this embodiment further includes a fixed base plate 300, which is detachably connected to the bottom surface of the lower fixed plate 120 by a fixing member. The fixed base plate 300 is provided with a plurality of positioning grooves 310 for the bottom end of the liquid collection tube 140 to extend into, and elastic members 330 are installed in the positioning grooves 310.

[0034] In this embodiment, two pairs of centrally symmetrical lower positioning holes 320 are provided on the edge of the fixed base plate 300. The lower fixed plate 120 is provided with an upper positioning hole (not shown in the figure) corresponding to the lower positioning holes. A vertical support rod 340 is provided between the lower positioning holes 320 and the upper positioning holes. The bottom end and the top end of the vertical support rod 340 extend into the lower positioning holes 320 and the upper positioning holes, respectively, so that the fixed base plate 300 is installed below the lower fixed plate 120.

[0035] In this embodiment, the second through hole 122 is a through hole without a threaded groove. When installing the liquid collecting tube 140, the top end of the liquid collecting tube 140 is directly inserted into the second through hole 122, and the bottom end is inserted into the positioning groove 310 and abuts against the elastic member 330, so that the liquid collecting tube 140 can be stably placed between the lower fixing plate 120 and the fixing base plate 300. This arrangement makes it more convenient and faster to put in and take out the liquid collecting tube 140.

[0036] Example 3

[0037] refer to Figure 6Compared with Example 1, the difference is that the portable solid phase extraction device described in this example also includes a liquid inlet 400.

[0038] Because the solid column 210 is small in volume, manual addition and solvent switching are required for elution with a large amount of solvent or with different solvents. In this embodiment, the liquid inlet 400 includes at least one liquid inlet container 410 and a liquid inlet pipe 420 connected to the liquid inlet container 410; the liquid inlet container 410 is used to hold a large amount of elution solvent.

[0039] In this embodiment, the liquid inlet section includes two liquid addition containers 410, and the liquid inlet pipe 420 has two liquid inlets, which are respectively connected to the two liquid addition containers 410. A liquid inlet valve 421 is provided on the liquid inlet pipe 420 near the liquid inlet. Using the solid-phase extraction device provided in this embodiment, the elution solvent can be switched by controlling the liquid inlet valve, and there is no need for continuous manual liquid addition.

[0040] Although embodiments of the present invention have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the claims and their equivalents.

Claims

1. A portable solid-phase extraction device, characterized in that, It includes a segmented collection section and an extraction section located above the segmented collection section; wherein, the extraction section includes a solid column and a control valve connected to the bottom outlet of the solid column; The segmented collection section includes an upper fixed plate, a lower fixed plate, a liquid outlet pipe, and several detachable liquid collection pipes. The lower fixed plate has an upward-opening T-shaped groove along its length. The upper fixed plate is a T-shaped block that matches the T-shaped groove. The upper fixed plate and the lower fixed plate are slidably connected. The middle of the upper fixed plate has a first through hole that matches the diameter of the liquid outlet pipe. The top end of the liquid outlet pipe is connected to the control valve, and the bottom end extends into the first through hole. The lower fixed plate in the T-shaped groove has several second through holes that match the top of the liquid collection pipes along its length. The top of the liquid collection pipes is inserted into the second through holes.

2. The portable solid-phase extraction device according to claim 1, characterized in that, An air hole is also provided on the upper fixing plate near the first through hole, and the horizontal center distance between the first through hole and the air hole is smaller than the radius of the second through hole.

3. The portable solid-phase extraction device according to claim 1, characterized in that, The outer wall of the top of the liquid collecting pipe is provided with a threaded groove, and the second through hole is a threaded through hole that matches the threaded groove on the outer wall of the liquid collecting pipe.

4. The portable solid-phase extraction device according to claim 1, characterized in that, The length of the upper fixing plate is greater than or equal to twice the farthest distance between the first and last second through holes on the lower fixing plate.

5. A portable solid-phase extraction device according to claim 1, characterized in that, The solid phase extraction device also includes a fixed base plate, which is detachably connected to the bottom surface of the lower fixed plate by a fastener. The fixed base plate has a plurality of positioning grooves for the bottom end of the liquid collection tube to extend into.

6. A portable solid-phase extraction device according to claim 5, characterized in that, The positioning groove is equipped with an elastic element, and the bottom end of the liquid collection tube abuts against the elastic element.

7. A portable solid-phase extraction device according to claim 5, characterized in that, At least one pair of centrally symmetrical lower positioning holes are provided on the edge of the fixed base plate, and an upper positioning hole is provided on the lower fixed plate corresponding to the lower positioning holes. A vertical support rod is provided between the lower positioning holes and the upper positioning holes.

8. A portable solid-phase extraction device according to claim 1, characterized in that, The solid-phase extraction apparatus further includes a liquid inlet section, which includes at least one liquid addition container and a liquid inlet pipe connected to the liquid addition container. The liquid inlet pipe has at least one liquid inlet, and each liquid inlet is connected to a liquid addition container. A liquid inlet valve is provided near the liquid inlet of the liquid inlet.

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