Cover sticking prevention reaction tube

By designing an anti-stick cap structure in the reaction tube and using claws to prevent the lyophilized microspheres from contacting the cap, the problem of lyophilized microsphere adhesion was solved, ensuring storage integrity and experimental accuracy.

CN224118996UActive Publication Date: 2026-04-14NANJING POCLIGHT BIOTECHNOLOGY CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2023-12-05
Publication Date
2026-04-14

AI Technical Summary

Technical Problem

Freeze-dried microspheres are prone to electrostatic adhesion to the cap in the reaction tube, which can lead to loss of the microspheres when the cap is opened, affecting the accuracy of the experimental results.

Method used

A reaction tube with an anti-stick cap was designed, comprising a cap, an anti-stick tube, and a reaction tube body. The anti-stick tube has claws inside, and the through-hole between the claws is smaller than the diameter of the freeze-dried microspheres, preventing the microspheres from contacting the cap. A seal is achieved through a snap-fit ​​connection.

Benefits of technology

This effectively prevents freeze-dried microspheres from adhering to the tube cap, ensuring the integrity of microsphere storage and improving the accuracy and reliability of experimental data.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses an anti-sticking reaction tube, which particularly relates to the field of reaction tube structures and comprises a tube cover. The anti-sticking pipe is detachably connected with the pipe cover in a sealing manner and comprises a fixed pipe section and a clamping jaw which are fixedly connected with each other; the reaction tube body is connected with the fixed tube section of the anti-sticking tube in a clamping manner, the clamping jaws extend into the reaction tube body, the diameter of a passing opening formed among the clamping jaws is smaller than that of a single freeze-drying microsphere, the three clamping jaws can be uniformly distributed at the lower end of the fixed tube section in an opening manner, and the clamping jaws form a horn shape. The anti-sticking tube is in a horn shape, a small opening of the horn shape faces downwards, the diameter of the small opening of the horn shape is smaller than that of a single freeze-drying microsphere, the top of the anti-sticking tube is turned outwards to form a buckle, a clamping groove is formed in the outer side of the top of the reaction tube body, and the buckle is matched with the clamping groove in a clamped mode. The effect of isolating the freeze-dried microspheres at the bottom of the reaction tube body from the tube cover can be achieved, so that the freeze-dried microspheres are prevented from being adhered to the tube cover.
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Description

Technical Field

[0001] This utility model relates to the field of reaction tube structure, and more specifically, to a reaction tube with an anti-stick cap. Background Technology

[0002] Lyophilized microspheres are often added using reaction tubes. Currently, lyophilized microspheres are usually stored inside reaction tubes, with a sealing cap separating the inside and outside of the reaction tube to protect the lyophilized microspheres from contamination and improve the accuracy of laboratory bacterial culture data.

[0003] Existing reaction tubes for storing lyophilized microspheres are prone to static electricity due to the small diameter, light weight, and extremely low water content of the lyophilized microspheres, which causes them to adhere to the sealing cap. This results in the lyophilized microspheres being easily lost along with the cap when it is opened. Utility Model Content

[0004] In order to overcome the above-mentioned defects of the prior art, the embodiments of this utility model provide a reaction tube with an anti-stick cap. The technical problem to be solved by this utility model is that static electricity is easily generated between the freeze-dried microspheres and the reaction tube, which makes it easy for the freeze-dried microspheres to be lost along with the cap when the cap is opened.

[0005] To achieve the above objectives, this utility model provides the following technical solution: an anti-sticking cap reaction tube, including a cap; and an anti-sticking tube that is detachably connected to the cap, the anti-sticking tube including a fixed tube segment and claws that are fixedly connected to each other; and a reaction tube body, the reaction tube body and the fixed tube segment of the anti-sticking tube being engaged and connected, the claws extending into the interior of the reaction tube body, and the diameter of the through-hole formed between several claws being smaller than the diameter of a single freeze-dried microsphere.

[0006] In a preferred embodiment, there are three clamps, which are evenly and openably arranged at the lower end of the fixed pipe section.

[0007] In a preferred embodiment, several claws are arranged in a trumpet shape, with the small opening of the trumpet facing downwards, and the diameter of the small opening of the trumpet is smaller than the diameter of a single freeze-dried microsphere.

[0008] In a preferred embodiment, there is a gap between each of the grippers and the inner wall of the reaction tube body.

[0009] In a preferred embodiment, the top of the anti-stick tube is turned outward to form a buckle, and a slot is provided on the outer side of the top of the reaction tube body, with the buckle and the slot engaging in a locking fit.

[0010] In a preferred embodiment, the cap and the anti-stick tube engage in a snap-fit ​​configuration.

[0011] In a preferred embodiment, a stress-bearing plate is integrally formed on the pipe cap.

[0012] In a preferred embodiment, the inner diameter of the reaction tube body is larger than the diameter of a single lyophilized microsphere but smaller than the sum of the diameters of two lyophilized microspheres.

[0013] In a preferred embodiment, the inner wall of the anti-stick tube and the outer shell of the pipette tip are fitted with a clearance, and the anti-stick tube is used to guide the pipette tip to move along the extension direction of the anti-stick tube.

[0014] The technical effects and advantages of this utility model are as follows:

[0015] By inserting an anti-adhesion tube into the reaction tube body, the freeze-dried microspheres located at the bottom of the reaction tube body and the tube cap can be isolated, thereby preventing the freeze-dried microspheres from adhering to the tube cap. Attached Figure Description

[0016] The accompanying drawings are provided to further understand the technical solution of this utility model and constitute a part of this utility model. The embodiments of this utility model and their descriptions are used to explain this utility model and do not constitute an improper limitation of this utility model.

[0017] Figure 1 This is a structural diagram of the internal structure of the reaction tube in this utility model.

[0018] Figure 2 This is a cross-sectional view of the reaction tube in this utility model.

[0019] Figure 3 This is a side view of the reaction tube in this utility model.

[0020] Figure 4 This is a cross-sectional view of the sample dispensing nozzle after it has been inserted into the reaction tube in this utility model.

[0021] The attached diagram is labeled as follows: 1. Tube cap; 2. Anti-stick tube; 3. Reaction tube body; 4. Lyophilized microspheres. Detailed Implementation

[0022] Exemplary embodiments will now be described more fully with reference to the accompanying drawings. However, these exemplary embodiments can be implemented in many forms and should not be construed as limited to the examples set forth herein; rather, they are provided so that the description of this disclosure will be more complete and fully convey the concept of the exemplary embodiments to those skilled in the art. The drawings are merely illustrative of this disclosure and are not necessarily drawn to scale. The same reference numerals in the drawings denote the same or similar parts, and therefore repeated descriptions of them will be omitted.

[0023] Furthermore, the described features, structures, or characteristics can be combined in any suitable manner in one or more exemplary embodiments. Numerous specific details are provided in the following description to give a full understanding of exemplary embodiments of this disclosure. However, those skilled in the art will recognize that the technical solutions of this disclosure can be practiced with one or more of the specific details omitted, or other methods, components, steps, etc., can be employed. In other instances, well-known structures, methods, implementations, or operations are not shown or described in detail to avoid obscuring various aspects of this disclosure.

[0024] This utility model provides, for example Figure 1 - Figure 4 The reaction tube shown includes a cap 1, an anti-stick tube 2, and a reaction tube body 3. The anti-stick tube 2 is snapped into the reaction tube body 3, and the cap 1 is detachably and sealingly connected to the anti-stick tube 2.

[0025] It's important to know that lyophilized microspheres are produced by dripping reagents or solutions into liquid nitrogen using a specialized precision micro-pump, rapidly freezing them into uniformly shaped, small solid spheres at extremely low temperatures for a very short time. These spheres are then collected and stored in a small lyophilization device.

[0026] The usage sequence of this design is as follows: First, place the reaction tube body 3 in a low temperature and low humidity environment, then put a number of freeze-dried microspheres 4 into the reaction tube body 3, then insert the anti-stick tube 2 into the reaction tube body 3, and make the upper part of the anti-stick tube 2 and the upper part of the reaction tube body 3 fasten together, and then plug the tube cap 1 into the anti-stick tube 2 to complete the storage of a number of freeze-dried microspheres 4.

[0027] The pipe cover 1 is integrally formed with a stress plate, which makes it easy for users to disassemble the pipe cover 1.

[0028] The cap 1 can be assembled with the anti-stick tube 2 using a straight plug type, a threaded tightening type, or a snap-fit ​​connection type. In this embodiment, considering the processing cost, a snap-fit ​​connection type is preferred, and the two are sealed together.

[0029] The anti-stick tube 2 includes a fixed tube section and a clamp. The top of the fixed tube section is turned outward to form a buckle. A groove is opened on the outer side of the top of the reaction tube body 3. The buckle and the groove are engaged and connected from the outside, so that the groove, which is prone to bacterial growth, will not introduce bacteria into the interior of the reaction tube body 3.

[0030] By uniformly fixing several claws to the fixed tube section in a trumpet shape, with the small opening of the trumpet facing the bottom of the reaction tube body 3, and leaving a through-hole in the center of the claw, the diameter of the through-hole is smaller than the average diameter of a single freeze-dried microsphere 4, so as to prevent the freeze-dried microsphere 4 located at the bottom of the reaction tube body 3 from passing through the through-hole formed by several claws. That is, by hindering the contact between the freeze-dried microsphere 4 and the tube cap 1, the purpose of preventing the freeze-dried microsphere 4 from sticking to the tube cap 1 is achieved.

[0031] Due to the trumpet-shaped design, there will be a certain V-shaped gap between the claws and the inner wall of the reaction tube body 3. The existence of this gap provides a certain basis for the opening of several claws.

[0032] When injecting the sample solution into the reaction tube body 3, the pipette tip can pass through the through-hole from above the anti-stick tube 2. At this time, several grippers will provide a uniform clamping force to the pipette tip from the periphery. The top opening diameter of the anti-stick tube 2 is slightly larger than the diameter of the pipette tip, so that the pipette tip can be directly inserted into the bottom of the reaction tube body 3 without the need for precise manual positioning.

[0033] Furthermore, because the pipette tip cannot directly apply the sample solution to the lyophilized microspheres 4 when processing whole blood samples, it can lead to poor test results. Therefore, the diameter of the reaction tube body 3 is designed to be larger than the average diameter of a single lyophilized microsphere 4 but smaller than the average diameter of two lyophilized microspheres 4. In this way, several lyophilized microspheres 4 are stored in the reaction tube body 3 in a stacked manner. When the pipette tip enters the bottom of the reaction tube body 3, the several lyophilized microspheres 4 will stagger their positions, making it easier for the outlet of the pipette tip to approach the bottom surface of the reaction tube body 3 to inject liquid. As the liquid is injected, it spreads upwards, successively submerging the lyophilized microspheres 4 from bottom to top, which is beneficial for obtaining more accurate test results.

[0034] Finally: The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A reaction tube with an anti-stick cap, characterized in that... include: Pipe cap (1); The cap (1) and the detachably connected anti-stick tube (2) are sealed together, the anti-stick tube (2) comprising a fixed tube section and a clamp that are fixedly connected to each other; and The reaction tube body (3) and the fixed tube section of the anti-stick tube (2) are engaged and connected. The claws extend into the interior of the reaction tube body (3). The diameter of the through-hole formed between several claws is smaller than the diameter of a single freeze-dried microsphere (4).

2. The anti-stick cap reaction tube according to claim 1, characterized in that: There are three clamps, which are evenly and can be opened and arranged at the lower end of the fixed pipe section.

3. The anti-stick cap reaction tube according to claim 1, characterized in that: The aforementioned claws are arranged in a trumpet shape, with the small opening of the trumpet facing downwards. The diameter of the small opening of the trumpet is smaller than the diameter of a single freeze-dried microsphere (4).

4. The anti-stick cap reaction tube according to claim 3, characterized in that: There is a gap between each of the grippers and the inner wall of the reaction tube body (3).

5. The anti-stick cap reaction tube according to claim 1, characterized in that: The top of the anti-stick tube (2) is turned outward to form a buckle, and a slot is provided on the outer side of the top of the reaction tube body (3). The buckle and the slot engage with each other.

6. The anti-stick cap reaction tube according to claim 1, characterized in that: The cap (1) and the anti-stick tube (2) are engaged and fitted together.

7. The anti-stick cap reaction tube according to claim 1, characterized in that: The cap (1) is integrally formed with a stress plate.

8. The anti-stick cap reaction tube according to claim 1, characterized in that: The inner diameter of the reaction tube body (3) is larger than the diameter of a single freeze-dried microsphere (4) but smaller than the sum of the diameters of two freeze-dried microspheres (4).

9. A reaction tube with an anti-stick cap according to claim 1, characterized in that: The inner wall of the anti-stick tube (2) and the outer shell of the sample dispensing tip are fitted with a clearance. The anti-stick tube (2) is used to guide the sample dispensing tip to move along the extension direction of the anti-stick tube (2).