A pharmaceutical reaction vessel with uniform mixing

Abstract

This utility model relates to the field of pharmaceutical reaction vessel technology, and discloses a pharmaceutical reaction vessel for uniform mixing, including a base plate and two triangular frames fixedly installed on the top of the base plate. A bearing seat is fixedly installed on the top of each of the two triangular frames. A rotating shaft is rotatably connected inside one of the bearing seats. A cross plate is fixedly connected to one end of the rotating shaft, and a fixing sleeve is detachably connected to one side of the cross plate by four bolts. This utility model, through the coordinated use of a drive assembly, a rotating assembly, a stirring assembly, and a rotating shaft, enables convective shearing through the rotation of the reaction vessel body and the counter-movement of the internal stirring blades. The material generates turbulence under the simultaneous radial, axial, and tangential forces. Compared to traditional stirring that relies solely on blade propulsion, which easily leads to sedimentation at the vessel edge, the rotation of the vessel body drives the overall movement of the material, and the counter-movement of the stirring blades breaks up boundary layer stagnation, effectively improving mixing efficiency.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical reaction vessel technology, specifically a pharmaceutical reaction vessel for uniform mixing. Background Technology

[0002] In the pharmaceutical industry, reaction vessels are one of the key pieces of equipment for drug synthesis, extraction, and mixing processes. To ensure the quality and stability of the drugs, the uniformity of mixing within the reaction vessel is crucial. However, existing reaction vessels typically employ traditional stirring methods. While these methods can accomplish basic stirring tasks, the uneven stirring can lead to insufficient mixing of materials, affecting reaction efficiency and the quality of the final product.

[0003] The flow field formed by a single stirring shaft has eddy zones, especially at the edge and bottom of the vessel, which leads to material stratification. At the same time, conventional stirring can only provide limited shear force and cannot effectively break up particle agglomerates, resulting in differences in dissolution. Although some pharmaceutical reactors on the market have adopted structures such as planetary stirrers, while they can improve uniformity, their transmission structure is complex, leading to increased maintenance costs. Furthermore, although some reactors with vessel rotation functions have solved the edge dead zone, they lack internal reverse shear, making the mixing effect of high solid content materials less than ideal.

[0004] Therefore, those skilled in the art have provided a pharmaceutical reaction vessel with uniform mixing to solve the problems mentioned in the background art. Utility Model Content

[0005] The purpose of this invention is to provide a pharmaceutical reaction vessel with uniform mixing to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides the following technical solution:

[0007] A pharmaceutical reaction vessel for uniform mixing includes a base plate and two tripods fixedly mounted on the top of the base plate. Each of the two tripods has a bearing fixedly mounted on its top. A rotating shaft is rotatably connected inside one of the bearings. A cross plate is fixedly connected to one end of the rotating shaft. A fixing sleeve is detachably connected to one side of the cross plate via four bolts. The reaction vessel body is fixedly mounted on the inner wall of the fixing sleeve. A drive assembly capable of driving the reaction vessel body to rotate is provided on one side of one of the tripods. A stirring assembly is provided inside the reaction vessel body. A sealing cover is detachably mounted on the side of the reaction vessel body away from the cross plate via threads. A connecting assembly is provided on the side of the sealing cover close to the reaction vessel body. A rotating assembly is provided on the top of one of the tripods via a support plate.

[0008] The base plate and tripod form the basic load-bearing structure. The tripod provides high stability support, and the inclined structure disperses torque stress to avoid resonance displacement during bidirectional rotation. Precision bearings are built into the bearing seat to achieve low-friction rotation of the shaft. The fixing sleeve firmly fixes the reactor body to the cross plate to ensure that the reactor does not shift. The reactor body can hold and process pharmaceutical materials and is the main container of the reactor. The rotation and stirring action of the reactor body ensure the uniform mixing of materials.

[0009] As a further description of the above technical solution:

[0010] The drive assembly includes a drive motor fixedly mounted on one side of one of the tripods, the output end of which rotates through the tripod and is fixedly connected to a drive shaft.

[0011] One end of the drive shaft is rotatably connected to one side of another tripod. The drive motor provides power for the rotation of the reactor. The output end of the drive motor is connected through the drive shaft to control the rotation of the entire reactor.

[0012] As a further description of the above technical solution:

[0013] Two gears are fixedly sleeved on the outer wall of the drive shaft, and both gears are meshed with an external gear ring.

[0014] The inner wall of the external gear ring is fixedly connected to the reactor body, ensuring that the reactor body and the gear can rotate synchronously after meshing.

[0015] As a further description of the above technical solution:

[0016] The stirring assembly includes a support block fixedly installed on the inner wall of the reactor body, a stirring shaft rotatably connected inside the support block, and a number of stirring blades fixedly installed on the outer wall of the stirring shaft.

[0017] One end of the stirring shaft is rotatably connected to one end of the inner wall of the reactor body, and several stirring blades are arranged in a spiral.

[0018] As a further description of the above technical solution:

[0019] The connecting assembly includes a connecting rod rotatably mounted inside the sealing cover, and a spline groove is provided at one end of the connecting rod near the reactor body.

[0020] The spline groove and spline block are used to ensure that the connecting rod is fixedly connected to the stirring shaft, preventing loosening or slippage during rotation.

[0021] As a further description of the above technical solution:

[0022] A spline block is movably engaged inside the spline groove, and one side of the spline block is fixedly connected to one end of the stirring shaft.

[0023] As a further description of the above technical solution:

[0024] The rotating assembly includes a servo motor fixedly mounted on the top of one of the tripods via a support plate. The output end of the servo motor rotates through one of the bearing seats and is fixedly connected to a rotating rod. The end of the rotating rod is provided with a hexagonal slot.

[0025] The servo motor provides driving force for the rotating rod, controlling the rotation of the reactor. The servo motor can precisely control the rotation speed and direction. The rotating rod is driven by the servo motor, which drives the rotation of the hexagonal groove and the connecting rod, thereby promoting the rotation of the stirring shaft.

[0026] As a further description of the above technical solution:

[0027] The hexagonal slot has a hexagonal hollow block that is movably engaged inside, and the top of the hexagonal hollow block is threaded with a fixing bolt.

[0028] The hexagonal hollow block is slidably connected to the outer wall of the connecting rod, and the outer wall of the fixing bolt is detachably threaded to the opening on the connecting rod.

[0029] This utility model has the following beneficial effects:

[0030] 1. Compared with existing technologies, this pharmaceutical reaction vessel with uniform mixing achieves convective shearing through the coordinated use of drive components, rotating components, stirring components, and rotating shafts. The rotation of the reaction vessel body and the counter-movement of the internal stirring blades create turbulent flow. Under the simultaneous action of radial, axial, and tangential forces, the material generates turbulence. In contrast to traditional stirring that relies solely on blades, which easily leads to sedimentation at the vessel edge, the rotation of the vessel body drives the overall movement of the material. Combined with the counter-movement of the stirring blades, this breaks down the boundary layer stagnation, effectively improving mixing efficiency, avoiding sedimentation and uneven mixing, and ensuring that pharmaceutical materials are fully and uniformly mixed during the reaction process.

[0031] 2. Compared with existing technologies, this pharmaceutical reaction vessel with uniform mixing can support the separation of the reaction vessel body from the connecting components and drive components through the coordinated use of connecting components, sealing covers, fixing sleeves and cross plates. When cleaning or maintenance is required, it can be disassembled to achieve 360° cleaning without dead angles. Attached Figure Description

[0032] Figure 1 This is a three-dimensional schematic diagram of the overall structure of a pharmaceutical reaction vessel for uniform mixing proposed in this utility model;

[0033] Figure 2This is a three-dimensional schematic diagram from another angle of the overall structure of a pharmaceutical reaction vessel for uniform mixing proposed in this utility model.

[0034] Figure 3 This is a schematic diagram of the stirring assembly structure of a pharmaceutical reaction vessel for uniform mixing, as proposed in this utility model.

[0035] Figure 4 This is a schematic diagram of the rotating component structure of a pharmaceutical reaction vessel for uniform mixing, as proposed in this utility model.

[0036] In the diagram: 1. Base plate; 2. Triangular frame; 3. Shaft seat; 4. Rotating shaft; 5. Cross plate; 6. Fixing sleeve; 7. Reactor body; 8. Sealing cover; 9. Drive motor; 10. Drive shaft; 11. Gear; 12. External gear ring; 13. Support block; 14. Stirring shaft; 15. Stirring blade; 16. Connecting rod; 17. Spline groove; 18. Spline block; 19. Servo motor; 20. Rotating rod; 21. Hexagonal groove; 22. Hexagonal hollow block; 23. Fixing bolt. Detailed Implementation

[0037] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0038] Please see Figure 1-4In this embodiment of the invention, a pharmaceutical reaction vessel for uniform mixing includes a base plate 1 and two triangular frames 2 fixedly mounted on the top of the base plate 1. Each of the two triangular frames 2 has a bearing seat 3 fixedly mounted on its top. A rotating shaft 4 is rotatably connected inside one of the bearing seats 3. A cross plate 5 is fixedly connected to one end of the rotating shaft 4. A fixing sleeve 6 is detachably connected to one side of the cross plate 5 via four bolts. A reaction vessel body 7 is fixedly mounted on the inner wall of the fixing sleeve 6. A driving component capable of driving the reaction vessel body 7 to rotate is provided on one side of one of the triangular frames 2. A stirring component is provided inside the reaction vessel body 7. A sealing cover 8 is detachably mounted on the side of the reaction vessel body 7 away from the cross plate 5 via threads. A connecting component is provided on the side of the sealing cover 8 near the reaction vessel body 7. A rotating component is provided on the top of one of the triangular frames 2 via a support plate. The base plate 1 and the triangular frames 2 form the basic load-bearing structure. The triangular frames 2 provide high stability support, and the inclined structure disperses torque. To prevent resonance displacement during bidirectional rotation, a precision bearing is built into the bearing seat 3, enabling low-friction rotation of the rotating shaft 4. The fixing sleeve 6 firmly fixes the reactor body 7 onto the cross plate 5, ensuring that the reactor does not shift. The reactor body 7 can hold and process pharmaceutical materials and is the main container of the reactor. The rotation and stirring action of the reactor body 7 ensures uniform mixing of materials. Through the coordinated use of the drive component, rotating component, stirring component, and rotating shaft 4, the rotation of the reactor body 7 and the counter-movement of the internal stirring blades 15 can form convection shear. The materials generate turbulence under the simultaneous action of radial, axial, and tangential forces. Compared with traditional stirring that relies solely on blades, which easily leads to sedimentation at the edge of the reactor, the rotation of the reactor body drives the overall movement of the materials. Combined with the counter-stirring blades 15, this breaks the boundary layer stagnation, effectively improving mixing efficiency, avoiding sedimentation and uneven mixing of materials, and ensuring that pharmaceutical materials are fully and uniformly mixed during the reaction process.

[0039] The drive assembly includes a drive motor 9 fixedly mounted on one side of one of the tripods 2. The output end of the drive motor 9 rotates through the tripod 2 and is fixedly connected to a drive shaft 10. One end of the drive shaft 10 is rotatably connected to one side of the other tripod 2. The drive motor 9 provides power for the rotation of the reactor. The output end of the drive motor 9 is connected through the drive shaft 10 to control the rotation of the entire reactor. The outer wall fixing sleeve 6 of the drive shaft 10 is provided with two gears 11. Both gears 11 are meshed with an external gear ring 12. The inner wall of the external gear ring 12 is fixedly connected to the reactor body 7 to ensure that the reactor body 7 can rotate synchronously after meshing with the gears 11.

[0040] The stirring assembly includes a support block 13 fixedly installed on the inner wall of the reactor body 7. A stirring shaft 14 is rotatably connected inside the support block 13. Several stirring blades 15 are fixedly installed on the outer wall of the stirring shaft 14. One end of the stirring shaft 14 is rotatably connected to one end of the inner wall of the reactor body 7. The several stirring blades 15 are arranged in a spiral.

[0041] The connecting assembly includes a connecting rod 16 rotatably installed inside the sealing cover 8. A spline groove 17 is provided at one end of the connecting rod 16 near the reactor body 7. The connecting rod 16 is fixedly connected to the stirring shaft 14 through the cooperation of the spline groove 17 and the spline block 18, so as to avoid loosening or slippage during rotation. The spline block 18 is movably engaged inside the spline groove 17, and one side of the spline block 18 is fixedly connected to one end of the stirring shaft 14.

[0042] The rotating assembly includes a servo motor 19 fixedly mounted on the top of one of the tripods 2 via a support plate. The output end of the servo motor 19 rotates through one of the bearing seats 3 and is fixedly connected to a rotating rod 20. The end of the rotating rod 20 is provided with a hexagonal slot 21. The servo motor 19 provides driving force to the rotating rod 20 and controls the rotation of the reactor. The servo motor 19 can precisely control the rotation speed and direction. The rotating rod 20 is driven by the servo motor 19, which drives the rotation of the hexagonal slot 21 and the connecting rod 16, thereby promoting the rotation of the stirring shaft 14. A hexagonal hollow block 22 is movably engaged inside the hexagonal slot 21. A fixing bolt 23 is threadedly connected to the top of the hexagonal hollow block 22. The hexagonal hollow block 22 is slidably connected to the outer wall of the connecting rod 16. The outer wall of the fixing bolt 23 is detachably threadedly connected to the opening on the connecting rod 16.

[0043] The working principle of this utility model is as follows: First, during use, the sealing cover 8 is rotated and removed. Then, the pharmaceutical material is placed into the reaction vessel body 7. Next, the spline groove 17 on the connecting rod 16 is aligned with the spline block 18 on the stirring shaft 14, so that they are engaged. Then, the sealing cover 8 is rotated in the opposite direction to fix it on the reaction vessel body 7. Then, the external gear ring 12 on the reaction vessel body 7 is aligned and engaged with the gear 11 on the drive shaft 10. At this time, the threaded hole on the cross plate 5 is aligned with the hole on the fixing sleeve 6. Then, the cross plate 5 and the fixing sleeve 6 are fixed by bolt connection. Then, the hexagonal hollow block 22 on the connecting rod 16 is pulled to engage with the hexagonal groove 21 on the rotating rod 20. Then, the fixing bolt 23 is tightened to fix the rotating rod 20 and the connecting rod 16. Then, the drive motor 9 and the servo motor 19 can be started. The rotation direction of the output end of the drive motor 9 is opposite to the tightening direction of the sealing cover 8 to prevent reaction. During the rotation of the reactor body 7, the sealing cover 8 is loosened. Then, the output end of the drive motor 9 drives the drive shaft 10 to rotate, which in turn drives the gear 11 to rotate, causing the external gear ring 12 meshing with the gear 11 to rotate. Thus, under the support of the rotating shaft 4 and the connecting rod 16, the reactor body 7 rotates. At the same time, the output end of the servo motor 19 rotates, driving the rotating rod 20 to rotate, causing the hexagonal hollow block 22, which is engaged inside the hexagonal groove 21, to rotate. Under the fixation of the fixing bolt 23, the connecting rod 16 also rotates synchronously, causing the spline block 18 on the stirring shaft 14 to rotate synchronously with the spline groove 17 on the connecting rod 16. This drives the stirring blade 15 to stir inside the reactor body 7. Furthermore, the rotation direction of the output end of the servo motor 19 is opposite to that of the drive motor 9, which ensures a good mixing effect during the rotation of the reactor and effectively avoids the problems of material sedimentation or uneven mixing, ensuring that the material can obtain continuous and uniform stirring during the reaction process.

[0044] The above are merely preferred embodiments of this utility model, but the scope of protection of this utility model is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the scope of the technology disclosed in this utility model, based on the technical solution and inventive concept of this utility model, should be included within the scope of protection of this utility model.

Claims

1. A pharmaceutical reaction kettle capable of mixing uniformly, comprising a bottom plate (1) and two tripods (2) fixedly installed on the top of the bottom plate (1), characterized in that, Both of the tripods (2) are fixedly mounted with a bearing seat (3) at their tops. A rotating shaft (4) is rotatably connected inside one of the bearing seats (3). A cross plate (5) is fixedly connected to one end of the rotating shaft (4). A fixing sleeve (6) is detachably connected to one side of the cross plate (5) by four bolts. A reactor body (7) is fixedly mounted on the inner wall of the fixing sleeve (6). A drive assembly capable of driving the reactor body (7) to rotate is provided on one side of one of the tripods (2). A stirring assembly is provided inside the reactor body (7). A sealing cover (8) is detachably mounted on the side of the reactor body (7) away from the cross plate (5) by threads. A connecting assembly is provided on the side of the sealing cover (8) close to the reactor body (7). A rotating assembly is provided on the top of one of the tripods (2) by a support plate.

2. The pharmaceutical reaction vessel for uniform mixing according to claim 1, characterized in that, The drive assembly includes a drive motor (9) fixedly installed on one side of one of the tripods (2), the output end of the drive motor (9) rotatably passes through the tripod (2) and is fixedly connected to a drive shaft (10), one end of the drive shaft (10) is rotatably connected to one side of the other tripod (2).

3. A pharmaceutical reaction vessel for uniform mixing according to claim 2, characterized in that, The outer wall fixing sleeve (6) of the drive shaft (10) is provided with two gears (11), and both gears (11) are meshed with an external gear ring (12). The inner wall of the external gear ring (12) is fixedly connected to the reactor body (7).

4. A pharmaceutical reaction vessel for uniform mixing according to claim 1, characterized in that, The stirring assembly includes a support block (13) fixedly installed on the inner wall of the reactor body (7). The support block (13) is rotatably connected to a stirring shaft (14). Several stirring blades (15) are fixedly installed on the outer wall of the stirring shaft (14). One end of the stirring shaft (14) is rotatably connected to one end of the inner wall of the reactor body (7). The several stirring blades (15) are arranged in a spiral.

5. A pharmaceutical reaction vessel for uniform mixing according to claim 1, characterized in that, The connecting assembly includes a connecting rod (16) rotatably installed inside the sealing cover (8), and a spline groove (17) is provided at one end of the connecting rod (16) near the reactor body (7).

6. A pharmaceutical reaction vessel for uniform mixing according to claim 5, characterized in that, The spline groove (17) is internally fitted with a spline block (18), and one side of the spline block (18) is fixedly connected to one end of the stirring shaft (14).

7. A pharmaceutical reaction vessel for uniform mixing according to claim 1, characterized in that, The rotating assembly includes a servo motor (19) fixedly mounted on the top of one of the tripods (2) via a support plate. The output end of the servo motor (19) rotates through one of the bearing seats (3) and is fixedly connected to a rotating rod (20). The end of the rotating rod (20) is provided with a hexagonal groove (21).

8. A pharmaceutical reaction vessel for uniform mixing according to claim 7, characterized in that, The hexagonal slot (21) is internally connected to a hexagonal hollow block (22), and the top of the hexagonal hollow block (22) is threaded with a fixing bolt (23). The hexagonal hollow block (22) is slidably connected to the outer wall of the connecting rod (16), and the outer wall of the fixing bolt (23) is detachably threaded to the opening on the connecting rod (16).

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