A melting device for use in a gel permeation chromatograph

Abstract

A melting device for gel chromatography, belonging to the field of auxiliary technology for detection mechanisms, includes a crucible, a sealed cylinder, a sealed cap, an electric push rod, an electric heating mechanism, a base plate, and a vibration motor. The crucible, sealed cylinder, sealed cap, electric push rod, electric heating mechanism, base plate, and vibration motor are assembled together. An isolation plate with a shaft hole is fixedly installed in the middle of the sealed cylinder, dividing the upper and lower ends of the sealed cylinder into a heating chamber and an equipment chamber. Under the combined action of these mechanisms, the analyte in the crucible can be sealed and heated through the sealed cap, thus improving heating efficiency and achieving energy savings. The vibration energy generated by the vibration motor causes synchronous vibration of the analyte in the crucible, ensuring uniform heating of the solid analyte and reducing the probability of excessive heat-induced denaturation of the analyte at the lower end of the crucible, thereby maximizing the accuracy of the detection data of the analyte in the gel chromatography. In summary, this invention has good application prospects.

Description

Technical Field

[0001] This utility model belongs to the field of auxiliary technology for testing institutions, and in particular, it is a melting device for gel chromatography. Background Technology

[0002] Gel permeation chromatography (GPC) is a separation and analysis device based on differences in molecular size. It is mainly used to determine the relative molecular mass and distribution of polymers and is widely used in materials science, chemical engineering, biopharmaceuticals and other fields. The working separation mechanism is based on differences in molecular size. Large molecules preferentially flow out through the gaps in the gel, while small molecules flow out after entering the pores. The application range can support the analysis of water and oil polymers, including synthetic polymers, biomacromolecules and polyolefins. Its core functions are as follows: (1) Molecular weight determination: polymers of different molecular weights are separated by gel column and molecular weight distribution is analyzed in real time by combining detectors (such as differential detectors); (2) Reaction monitoring: the effect of polymerization reaction conditions on the molecular weight of products is monitored in real time to optimize process parameters; (3) Material analysis: material degradation, copolymer composition and residual monomers are detected during the processing (accuracy can reach 0.1 ppm level).

[0003] Before detecting solid substances (such as PEEK, polypropylene, etc.) in a gel chromatography instrument, it is necessary to first melt the substance to be detected using an external crucible, and then pour the molten substance in the crucible into the corresponding injection tube of the gel chromatography instrument using clamps, etc. (the injection tube is equipped with an external heating mechanism so that the substance to be detected can flow in and out of the gel chromatography instrument), and then the gel chromatography instrument completes the entire detection and analysis process under its own function. Although the crucible heating of the substance to be detected meets the material melting and heating requirements to a certain extent, it also has the following technical problems due to structural limitations. (1): The crucible is exposed to the outside during the heating process, which easily causes heat to dissipate into the air, resulting in a longer heating time and correspondingly higher energy consumption (such as higher electricity consumption); (2) During the entire heating process, the crucible is in a fixed and non-moving state, which may lead to excessive heat absorption and denaturation of the substance at the lower end of the crucible, which may have an adverse effect on the subsequent detection and analysis effect of the substance. In summary, it is particularly necessary to provide a device that can improve heating efficiency and reduce denaturation of the substance to be detected. Utility Model Content

[0004] To overcome the shortcomings of existing crucibles used in gel chromatographs, which are limited by their structure and have the drawbacks described in the background art, this utility model provides a melting device for gel chromatographs that, under the combined action of related mechanisms, can seal and heat the substance to be detected, thereby improving heating efficiency and vibrating the substance to be detected during heating. This ensures that the solid substance to be detected in the container is heated evenly, reducing the probability of excessive heat-induced denaturation and maximizing the accuracy of the detection data.

[0005] The technical solution adopted by this utility model to solve its technical problem is:

[0006] A melting device for gel chromatography includes a crucible, a sealing cylinder, a sealing cap, an electric actuator, an electric heating mechanism, a base plate, and a vibration motor. The lower end of the sealing cylinder is fixedly mounted on the upper end of the base plate. The upper end of the sealing cylinder has an open structure. An isolation plate with a shaft hole is fixedly installed inside the sealing cylinder, dividing the upper and lower ends of the sealing cylinder into a heating chamber and an equipment chamber. The vibration motor is fixedly installed in the lower end of the equipment chamber. There are at least two sets of electric actuators. The lower end of the first set of electric actuators is fixedly installed in the lower end of the equipment chamber. A support plate is fixedly installed on the upper end of the first set of electric actuators. The electric heating mechanism includes a heating shell and an electric heating tube. The electric heating tube is fixedly installed in the heating shell. A heat-insulating ceramic pad is fixedly installed on the upper end of the support plate. The support plate and the lower end of the heating shell are fixedly installed together. The heating shell is located in the lower end of the heating chamber. The lower end of the crucible is fixedly installed on the upper end of the heating shell. A support column is fixedly installed at the rear end of the base plate. The upper side of the second set of electric actuators is fixedly installed on the lower side of the upper end of the support base. The upper end of the sealing cap is fixedly installed on the lower side of the second set of electric actuators.

[0007] Furthermore, the inner diameter of the shaft hole is larger than the outer diameter of the first set of electric push rod movable column.

[0008] Furthermore, the outer diameter of the crucible and heating shell is smaller than the inner diameter of the sealing cylinder.

[0009] Furthermore, the outer diameter of the sealing cap is larger than the outer diameter of the sealing cylinder.

[0010] Furthermore, the lower end of the equipment compartment has several heat dissipation holes around its perimeter.

[0011] Furthermore, when the movable column of the first set of electric push rods is at the lower dead center, the upper end of the crucible is lower than the upper end of the sealing cylinder; when the movable column of the first set of electric push rods is at the upper dead center, the lower end of the crucible is higher than the upper end of the sealing cylinder.

[0012] Furthermore, when the movable column of the second set of electric push rods is at the lower dead center, the lower end of the sealing cover and the upper end of the sealing cylinder are in sealing contact. When the movable column of the second set of electric push rods is at the upper dead center, the distance between the lower end of the sealing cover and the upper end of the sealing cylinder is greater than the height of the crucible.

[0013] Compared with existing technologies, the advantages of this invention are as follows: Under the combined action of relevant mechanisms, this invention can heat the substance to be tested in the crucible through a sealed lid, thus improving heating efficiency and achieving energy savings. The vibration energy generated by the vibrating motor causes the substance in the crucible to vibrate synchronously, ensuring uniform heating of the solid substance to be tested within the crucible. This reduces the probability of excessive heating and denaturation of the substance at the lower end of the crucible, and maximizes the accuracy of the detection data of the gel permeation chromatography. In summary, this invention has good application prospects. Attached Figure Description

[0014] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0015] Figure 1 This is a schematic diagram of the overall structure of this utility model.

[0016] Figure 2 This is the circuit diagram of this utility model. Detailed Implementation

[0017] Figure 1 , 2As shown, a melting device for gel chromatography includes a crucible 1, a sealed cylinder 2, a sealed cover 3, electric push rods M and M1, an electric heating mechanism, a base plate 4, a power module W1, power switches S and S1, and a vibration motor M. The lower end of the sealed cylinder 2 is fixedly installed on the upper end of the base plate 4. The upper end of the sealed cylinder 2 has an open structure. A partition plate 21 with a central shaft hole 211 is fixedly installed in the middle of the sealed cylinder 2, dividing the upper and lower ends of the sealed cylinder 2 into a heating chamber and an equipment chamber. There are two sets of vibration motors M2. The electric actuators M and M1 are fixedly installed on the lower left and right sides of the equipment compartment, respectively. There are at least two sets of electric actuators M and M1. The cylinder of the first set of electric actuators M is fixedly installed in the middle of the lower end of the equipment compartment, and its movable column is led out upward through the shaft hole 211 of the isolation plate. A metal support plate 5 is fixedly installed on the upper end of the movable column of the first set of electric actuators M. The support plate 5 has multiple fixing holes around its perimeter. The electric heating mechanism includes a heating shell 71 and an annular electric heating tube RT. The electric heating tube RT is fixedly installed in the upper part of the heating shell 71, and the lower part of the heating shell 71 is fixedly installed in the middle. Multiple bolts are used to fix the heating shell 71 onto the movable column of the first set of electric push rods M. A heat-insulating ceramic pad 6 is installed at the upper end of the support plate (to prevent excessive heat from acting on the electric push rod M). Multiple bolts extend downwards through multiple openings in the support plate 5 and are secured with nuts to fix the heating shell 71 onto the movable column of the first set of electric push rods M (the heat-insulating ceramic pad 6 is located between the upper part of the movable column and the lower end of the heating shell 71). The heating shell 71 is located at the lower end of the heating chamber. The lower end of the crucible 1 is fixedly installed on the upper part of the heating shell 71. A "˥"-shaped support is fixedly installed at the middle of the rear end of the base plate 4. Support column 41, the cylinder of the second set of electric push rods M1 is vertically distributed and fixedly installed on the lower front side of the upper end of the support base 41, and the upper middle part of the sealing cover 3 is fixedly installed on the lower side of the movable column of the second set of electric push rods M1; the two wires connected to the electric heating tube are respectively sleeved on the outside of multiple ceramic tubes, and the wires with length margin are led out through the opening at the lower front end of the heating chamber. The opening is sealed with heat-resistant sealant. The power switches S and S1 and the power module W1 are installed on the circuit board inside the control box 7. The control box 7 is fixedly installed on the lower front outer side of the sealing cylinder 2.

[0018] Figure 1 , 2As shown, the inner diameter of the shaft hole 211 is larger than the outer diameter of the movable column of the first set of electric actuators M. The outer diameters of the crucible 1 and the heating shell 71 are smaller than the inner diameter of the sealing cylinder 2. The outer diameter of the sealing cover 3 is larger than the outer diameter of the sealing cylinder 2. The lower end of the equipment chamber has several heat dissipation holes 8 (to dissipate heat from the equipment chamber). When the movable column of the first set of electric actuators M is at the bottom dead center, the upper end of the crucible 1 is lower than the upper end of the sealing cylinder 2; when the movable column of the first set of electric actuators M is at the top dead center, the lower end of the crucible 1 is higher than the upper end of the sealing cylinder 2. When the movable column of the second set of electric actuators M1 is at the bottom dead center, the lower end of the sealing cover 3 and the upper outer end of the sealing cylinder 2 are in sealing contact; when the movable column of the second set of electric actuators M1 is at the top dead center, the distance between the lower end of the sealing cover 3 and the upper outer end of the sealing cylinder 2 is greater than the height of the crucible 1. The power input terminals 1 and 2 of the two sets of vibration motors M2, the power input terminals 1 and 2 of the power module W1, the two ends of the power input of the electric heating tube RT, and the two poles of the AC 220V power supply are connected by wires. The power output terminals 3 and 4 of the power module W1 and the power input terminals 1 and 2 of the two power switches S and S1 are connected by wires. The power output terminals 3 and 4, 5 and 6 of the two power switches S and S1 and the positive and negative and negative positive pole power input terminals of the two sets of electric push rods M and M1 are connected by wires.

[0019] Figure 1 , 2 As shown, after the power input terminal of the power module W1 is energized, the 3rd and 4th pins of the power module W1 output a stable DC 24V power supply to the power input terminals of the two power switches S and S1. The usage process of this new type is as follows: (1): The operator moves the handle of the power switch S to the left by hand, and the 1st and 2nd pins and the 3rd and 4th pins of the power switch S are connected respectively. The positive and negative power input terminals of the electric push rod M are energized, and its movable column pushes the heating shell 71 to rise. After the heating shell 71 is located at the upper end of the sealing cylinder 2, the power switch S is turned off. Then the operator places the crucible 1 containing the substance to be tested on the heating shell 71. (2): The operator moves the handle of the power switch S to the right by hand, and the 1st and 2nd pins and the 5th and 6th pins of the power switch S are connected respectively. The negative and positive power input terminals of the electric push rod M are energized, and its movable column drives the heating shell 71 to fall. After the heating shell 71 is located at the lower end of the sealing cylinder 2, the power switch S is turned off. (3): The staff member moves the handle of the power switch S1 to the right, and pins 1 and 2 and pins 5 and 6 of the power switch S1 are connected respectively. The positive and negative power input terminals of the electric push rod M1 are energized, and its movable column drives the sealing cover 3 to descend. After the lower end of the sealing cover 3 contacts the upper end of the sealing cylinder 2, the power switch S1 is turned off. (4) The 220V power supply heating tube RT heats the crucible. The heating tube RT makes the substance to be tested in the crucible melt after being heated. After the power switch of the vibration motor M2 is turned on, the vibration motor M2 is energized and works to vibrate and heat the substance in the crucible (the upper end of the crucible and the lower end of the movable cover are in contact).

[0020] (5) After heating is complete, turn off the power switches of the vibration motor M2 and the electric heating tube RT. The operator moves the handle of the power switch S1 to the left. Pins 1 and 2 and pins 3 and 4 of the power switch S1 are connected respectively. The positive and negative power input terminals of the electric push rod M1 are energized, and its movable column drives the movable cover 3 to rise. After the lower end of the sealing cover 3 and the sealing cylinder 2 are separated by a large distance (higher than the height of the crucible), turn off the power switch S1. (6) The staff member moves the handle of the power switch S to the left, and pins 1 and 2 and pins 3 and 4 of the power switch S are connected respectively. The positive and negative power input terminals of the electric push rod M are energized, and its movable column drives the heating shell 71 to rise. After the heating shell 71 is located on the outer side of the upper end of the sealing cylinder 2, the power switch S is turned off. Then the staff member uses tools to remove the crucible and uses clamps to pour the molten material in the crucible into the corresponding injection tube of the gel chromatograph (the injection tube is equipped with an external heating mechanism so that the substance to be detected can flow in and out of the gel chromatograph). Then the gel chromatograph completes the entire detection and analysis process under its own function.

[0021] Figure 1 , 2 As shown above, through the combined action of relevant mechanisms, this utility model can heat the substance to be tested in the crucible through a sealed cap, thereby improving heating efficiency and achieving energy saving. The vibration energy generated by the vibration motor causes the substance in the crucible to vibrate, ensuring that the solid substance to be tested in the crucible is heated evenly, reducing the probability of excessive heat-induced denaturation of the substance at the lower end of the crucible, and ensuring the accuracy of the detection data of the substance to be tested by the gel chromatography as much as possible. Figure 2 In the middle, the power module W1 is a finished product of AC 220V to DC 24V power module; the electric push rods M and M1 are finished products of reciprocating electric telescopic rods; the vibration motor M2 has a power of 500W; and the electric heating tube RT is a finished product of stainless steel armored dry-burning electric heating tube with a power of 3KW.

[0022] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. It will be apparent to those skilled in the art that this utility model is limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or basic characteristics of this utility model. Therefore, the embodiments should be considered exemplary and non-limiting in all respects. The scope of this utility model is defined by the appended claims rather than the foregoing description, and thus all variations falling within the meaning and scope of equivalents of the claims are intended to be included within this utility model.

[0023] Furthermore, it should be understood that although this specification describes the embodiments, the embodiments do not necessarily contain only one independent technical solution. This way of describing the specification is only for clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in the embodiments can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A melting device for gel chromatography, comprising a crucible, a sealed cylinder, a sealed cap, an electric push rod, an electric heating mechanism, a base plate, and a vibration motor; characterized in that, The lower end of the sealing cylinder is fixedly installed on the upper end of the base plate. The upper end of the sealing cylinder has an open structure. An isolation plate with a shaft hole is fixedly installed inside the sealing cylinder, dividing the upper and lower ends of the sealing cylinder into a heating chamber and an equipment chamber. The vibration motor is fixedly installed in the lower end of the equipment chamber. There are at least two sets of electric push rods. The lower end of the first set of electric push rods is fixedly installed in the lower end of the equipment chamber. A support plate is fixedly installed on the upper end of the first set of electric push rods. The electric heating mechanism includes a heating shell and an electric heating tube. The electric heating tube is fixedly installed in the heating shell. A heat-insulating ceramic pad is fixedly installed on the upper end of the support plate. The support plate and the lower end of the heating shell are fixedly installed together. The heating shell is located in the lower end of the heating chamber. The lower end of the crucible is fixedly installed on the upper end of the heating shell. A support column is fixedly installed at the rear end of the base plate. The upper side of the second set of electric push rods is fixedly installed on the lower side of the upper end of the support base. The upper end of the sealing cover is fixedly installed on the lower side of the second set of electric push rods.

2. The melting device for gel chromatography according to claim 1, characterized in that, The inner diameter of the shaft hole is larger than the outer diameter of the first set of electric push rod movable column.

3. The melting device for gel chromatography according to claim 1, characterized in that, The outer diameter of the crucible and heating shell is smaller than the inner diameter of the sealing cylinder.

4. The melting device for gel chromatography according to claim 1, characterized in that, The outer diameter of the sealing cap is larger than the outer diameter of the sealing cylinder.

5. The melting device for gel chromatography according to claim 1, characterized in that, The lower part of the equipment compartment has several ventilation holes around its perimeter.

6. The melting device for gel chromatography according to claim 1, characterized in that, When the movable column of the first set of electric actuators is at the bottom dead center, the height of the upper end of the crucible is lower than the height of the upper end of the sealing cylinder; when the movable column of the first set of electric actuators is at the top dead center, the height of the lower end of the crucible is higher than the height of the upper end of the sealing cylinder.

7. The melting device for gel chromatography according to claim 1, characterized in that, When the movable column of the second set of electric actuators is at the bottom dead center, the lower end of the sealing cover and the upper end of the sealing cylinder are in sealing contact. When the movable column of the second set of electric actuators is at the top dead center, the distance between the lower end of the sealing cover and the upper end of the sealing cylinder is greater than the height of the crucible.

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