50 results about "Myocardial Contractions" patented technology

Systems and methods according to the invention employ an acceleration sensor to characterize the synchrony or dyssynchrony of the left ventricle. Patterns of acceleration related to myocardial contraction can be used to assess synchrony or dyssynchrony. Time-frequency transforms and coherence are derived from the acceleration. Information and numerical indices determined from the acceleration time frequency transforms and coherence can be used to find the optimal pacing location for cardiac resynchronization therapy. Similarly, the information can be used to optimize timing intervals including V to V and A to V timing.

The invention discloses an intelligent sleep monitoring system with a small contact surface. The intelligent sleep monitoring system consists of a physiological signal acquisition module, a micro control unit (MCU) control module, a power module, a sleeping posture adjustment module and an alarm and rescue module, wherein the physiological signal acquisition module balances the generated force due to myocardial contraction, chest contraction in the respiration process and other muscular movements in the lying process by adopting an air cushion, the body respiration, heart rate, displacement and other physiological signals are converted into electric signals through a pressure sensor, the electric signals are filtered and amplified and are transmitted to the MCU for processing and judging whether the abnormalities of sleep apnea, sudden cardiac arrest, drop and the like occur; when the abnormality is detected, the MCU drives a stepping motor, so that the pillow is deformed, the sleep respiration is adjusted, and corresponding audible and visual alarm is performed aiming at the abnormality. The contact area between the system and a measured body is small, a sensor is not required to be worn, the sleep is not influenced, the cost is low, and the operation, maintenance and management are convenient. The system can be used for a sleep monitoring system for performing daily household monitoring on young and old people.

The invention provides a traditional Chinese medicine preparation for treating liver-depression qi-stagnation type viral myocarditis. The traditional Chinese medicine preparation comprises the following components in parts by weight: 10-20 parts of radix bupleuri, 10-20 parts of cape jasmine, 10-20 parts of fructus forsythiae, 10-20 parts of radix pseudostellariae, 10-20 parts of prepared rehmannia root, 10-20 parts of cassia twig, 10-20 parts of fructus ligustri lucidi, 10-20 parts of oldenlandia diffusa, 10-20 parts of radix ophiopogonis, 10-20 parts of the root of red-rooted salvia, 10-20 parts of carthamus tinctorius, 10-20 parts of radix paeoniae alba, 10-20 parts of pseudo-ginseng, 10-20 parts of astragalus mongholicus, 10-20 parts of prepared fleece flower root, 10-20 parts of poria cocos, 10-20 parts of vegetable sponge, 10-20 parts of ligusticum wallichii, 10-20 parts of curcuma zedoary, 10-20 parts of scutellaria baicalensis, 10-20 parts of albizia julibrissin, 10-20 parts of silkworm larva, 10-20 parts of angelica sinensis, and 10-20 parts of platycladi seeds. The traditional Chinese medicine preparation disclosed by the invention is capable of rapidly in-flowing blood, directly achieving myocardium and rapidly increasing myocardial contraction force and has the main functions of detoxifying, removing stasis, clearing heat, opening the inhibited lung-energy and clearing away the heart-fire; in addition, the functions of tonifying qi and calming the mind and the functions of soothing the liver and reducing heat are combined, the functions of rapidly relieving patient conditions and saving lives of patients are achieved.

The present direct cardiac compression (DCC) design, termed Cardiac Resynchronization Compression Sac System (CRCSS), combines together the mechanical and electrical characteristics associated with DCC and cardiac resynchronization therapy (CRT), respectively. The CRCSS comprises a shell, at least one opening on the shell, and at least one inflatable balloon, and a pumping system. The shell is custom manufactured to substantially conform to the contour of a portion of a heart, the contour of the heart being obtained by an imaging system. The opening on the shell is designed for passing pericardial fluid so as not to impede the myocardial contraction. The inflatable balloon attaches to at least one predetermined location of the inner surface of the shell. Furthermore, the shell naturally positions in the pericardium space without resorting to any artificial force to prevent it from dislodging from the heart, and when the inflatable balloon inflates at least one ventricular free wall of the heart is compressed.

An implantable medical device applies an electric signal over two electrodes and measures the resulting electric signal over a candidate pair of neighboring electrodes on a lead for a first heart ventricle or over a candidate electrode of the lead and a case electrode. An impedance signal is determined for each candidate pair or electrode based on the applied signal and the measured resulting signal. A time difference between start of contraction in a second ventricle and the timing of local myocardial contraction as identified from the impedance signal at the site of the candidate pair or electrode is determined for each candidate pair or electrode. An optimal pacing electrode is selected to correspond to one of the electrodes of the candidate pair having the largest time difference or the candidate electrode having largest time difference.

The invention relates to a system (100) for visualizing a cardiac parameter at a plurality of positions in a myocardium and at a plurality of stress levels, the system comprising a determination unit parameter at a position from the plurality of positions in the myocardium and at a stress level from the plurality of stress levels on the basis of stress level cardiac functional data, and a visualization unit (120) for visualizing the determined value of the cardiac parameter by displaying a point in a viewing plane. The visualized points are defined by their polar coordinates in a polar coordinate system in the viewing plane. A radial coordinate of the point visualizes the determined value of the cardiac parameter. An angular coordinate of the point visualizes an angular coordinate of the position in the myocardium in a cylindrical coordinate system. Thus, the system allows easy numerical comparison of local myocardial contractions at different stress level values.

The invention discloses a myocardial excitation contraction coupling time diagnostic apparatus and application thereof. The diagnostic apparatus provided by the invention comprises an electrocardio collection unit, an ultrasonic heartbeat collection unit, an analysis processing unit and a data output unit, wherein the electrocardio collection unit is used for defecting myocardial electrical excitation; the ultrasonic heartbeat collection unit is used for detecting myocardial contraction; the analysis processing unit is used for recording the starting time of the myocardial electrical excitation detected by the electrocardio collection unit and the starting time of the myocardial contraction detected by the ultrasonic heartbeat collection unit and analyzing the time interval between the starting time of the myocardial electrical excitation and the starting time of the myocardial contraction; and the data output unit is used for outputting data obtained by the analysis processing unit. Experiments prove that the coupling delay time of the heart failure patients is markedly longer than that of the healthy volunteers so that the coupling delay time displayed by the diagnostic apparatus disclosed by the invention can be used for evaluating the heart function.

An implantable heart monitoring device including a sensing unit, a signal quality analysis unit, and an evaluation unit. The sensing unit is connected to at least one electrode that picks up electric potentials. The sensing unit processes electrical signals corresponding to the electric potentials, and generates sense signals including events corresponding to myocardial contractions. The signal quality analysis unit determines whether a noise condition (NC) and/or a low signal indication is present for an event and generates an indication signal. The evaluation unit evaluates the sense signals and the indication signals, treats a detected event as non-valid if a NC and/or low signal indication signal is present for that event, and uses only intervals defined by two consecutive events which do not have a NC and/or a low signal indication to determine a rate of events of the sense signal.

The invention discloses a nifedipine medicine composition and a preparation method thereof. The nifedipine medicine composition contains nifedipine, hydroxymethyl propyl cellulose and microcrystalline cellulose. The hydroxymethyl propyl cellulose is used as slow-releasing framework material; the weight ratio of the nifedipine and the hydroxymethyl propyl cellulose is 2:1-1:1; and the weight ratio of the nifedipine and the microcrystalline cellulose is 1:4-1:3; and lactose, starch, calcium hydrophosphate and glucose can be also added. The method for preparing the nifedipine medicine composition comprises the following steps of: (1) crushing and screening; (2) drying; and (3) tabletting. According to the invention, the dissolution rate of the nifedipine in the water can be increased, the coronary arteries in the normal blood supply area and the ischemic area are relaxed while the absorption rate of the nifedipine in the body is increased so that coronarospasm and is released and prevented and myocardial contraction is inhibited; myocardial oxygen consumption is reduced; the peripheral resistance is released; after load of heart is reduced; sinus node function and atrioventricular conduction of the isolated heart are slowed down; and the nifedipine medicine composition is applicable to variant angina pectoris, unstable angina pectoris and chronic stable angina pectoris.

The invention discloses deer heart health wine. A preparation method of the deer heart health wine comprises the following steps: taking a deer heart, ginseng, radix ophiopogonis, schizandra fruits, spina date seeds, platycladi seeds, radish seeds, caulis spatholobi, poria cocos, bighead atractylodes rhizome, liquorice, pawpaw and radix salviae miltiorrhizae, washing and then slicing the traditional Chinese medicines; putting the traditional Chinese medicine slices in pure grain white wine with an alcohol content of 60%, sealing the traditional Chinese medicine slices and wine in a pot and immersing the slices for a plurality of days; simultaneously transferring the immersed traditional Chinese medicine slices and wine into an extraction pot for reduced pressure extraction, filtering the traditional Chinese medicine dregs to obtain traditional Chinese medicine wine; transferring the traditional Chinese medicine wine into a sealing pot for storing for plurality of days to obtain the deer heart health wine. The deer heart health wine has the functions of regulating cardiac rhythm, increasing soluble blood volume, calming heart and nerves, enhancing myocardial contraction force, reinforcing spleen and generating blood, promoting blood circulation to remove blood stasis and clearing and activating the channels and collaterals, and has the health effects on insufficient blood supply to heart and brain, insomnia and amnesia, anemia, infarction of small cardiac blood vessels.

The invention discloses application of compound 5-bromo-2-(alpha-hydroxy amyl) sodium benzoate (BZP) in medicine for curing cardiovascular disease, and belongs to the field of medicinal chemistry. Experiments prove that BZP has a protective effect for acute and chronic myocardial ischemia reperfusion injuries of a mouse, so that the overall animal acute myocardial infarction area is reduced through BZP oral administration and intravenous injection, the myocardial infarction area of the acute ischemia reperfusion injury of the isolated perfusion heart of the mouse is reduced through BZP, the function of myocardial contraction is improved, and the haematological myocardial injury markers are reduced; moreover, the invention also relates to application for delaying a process of the conversionfrom myocardial hypertrophy to cardiac failure after chronic orally taken administration of BZP for acute myocardial infarction of the mouse and reducing ventricular remodeling caused by ischemic heart disease of the mouse, the therapeutic action of the cardiac function is improved obviously; moreover, the invention also relates to the transient effect of the compound BZP for reducing the blood pressure of the hypertension mouse (SHR mouse), and these results indicate that the BZP has effective research and development prospects of myocardial damage protection medicine for clinically acute and chronic myocardial infarctions.

Methods useful in the regulation of myocardial contraction are disclosed. The methods are useful in the regulation of heart function. The invention reveals that sorcin overexpression enhances cardiac contractile performance and establishes the concept of sorcin as a regulator of myocardial contractility. The invention also provides screening assays that allow for the identification of agents that modulate sorcin expression. Such agents are useful, for example, for diagnosing cardiac contractile function associated disorders in subjects, and treating the subjects with the agents identified as being able to modulate sorcin expression.

The invention discloses biscuits for preventing and treating hypertension, hyperlipidemia and hyperglycemia. According to the technical scheme, the biscuits comprise, by mass, 3 parts of buckwheat powder, 2 parts of kudzuvine root powder, 3 parts of black bean powder, 1 part of black fungus powder and 1 part of hawthorn fruit powder, and sesame oil serves as conditioning liquid. The buckwheat powder, the kudzuvine root powder, the black bean powder, the black fungus powder and the hawthorn fruit powder are compounded and mixed in proportion to serve as raw materials of the biscuits, the sesame oil serves as the conditioning liquid, the raw materials are blended into dough, formation and baking are conducted according to the current biscuit making technology, and then the biscuits are put into plastic bags for sale. Buckwheat improves hyperlipidemia, purifies blood and enables blood vessels to be healthy; kudzuvine roots contain puerarin, can slow down cardiac impulse, enhance myocardial contraction and lower aortic pressure; black beans can promote blood circulation and metabolic capability; black fungi have the effects of cleaning blood, removing toxic materials, resisting to cancer and coagulation and promoting fat decomposition and digestion; hawthorn fruits have the effects of strengthening the heart, resisting to arrhythmics and angina, lowering the blood pressure and expanding blood vessels. It is suitable to eat a small number of the biscuits.

The invention discloses application of hydrogen-enriched myocardium protecting liquid to preparation of medicines for treating myocardial damage. According to the application of the hydrogen-enrichedmyocardium protecting liquid to the preparation of medicinefor treating the myocardial damage, disclosed by the invention, an animal experiment proves that the hydrogen-enriched myocardium protectingliquid has good relieve functions on myocardial contraction dysfunction caused by the myocardial damage and oxygen radical variation caused by the myocardial damage when being used for treating an experimental dog, and the experimental dog treated by the hydrogen-enriched myocardium protecting liquid is capable of effectively reducing generation of myocardium metabolite caused by the myocardial damage, so that the hydrogen-enriched myocardium protecting liquid can be used as the medicine for treating the myocardial damage.

The invention relates to the technical field of medical treatment, in particular to a magnet therapy patch capable of being effectively used for treating a cardiovascular disease and a manufacturing method. The patch is composed of a patch body (medical proof fabric adhesive layer and protection layer), a magnet therapy layer made of magnetic materials and viscous agents and the like, the patch can be made to any shape according to use needs, and the patch has the advantages of improving blood circulation and human heart functions, strengthening the myocardial contraction force, improving angiotasis, eliminating inflammation of the blood vessel walls, strengthening the vitality of cells, improving the metabolism, reducing transmission of pain signals, preventing cholesterol precipitation, preventing myocardial infarction and thrombosis forming and the like, and is used for treating the cardiovascular disease, various inflammations, inflammatory edema, vascular scars and vascular sclerosis. Before the patch is used, different specifications and models are selected according to needs, when the patch is used, the protection layer is removed, the magnet therapy layer and the medical proof fabric adhesive layer in the patch body are directly and tightly attached to the precordium and the heart shu-acupoint, and each patch can be used for 1-2 days.

The invention relates to a ginseng stem leaf saponin granule for beasts and birds and a preparation method thereof, wherein the composing component of the granule and the parts by weight are respectively 1-6 parts of ginseng stem leaf saponin, and 34-39 parts of starch. The ginseng stem leaf saponin granule is the highly-effective component extracted from the stems and the leaves of natural traditional Chinese medicine ginseng, has the functions of nourishing and strengthening the body, relieving uneasiness and benefiting brain, increasing the immunizing power of organisms, regulating the internal secretion, increasing the myocardial contraction force, improving the functions of hearts and protecting the liver. The ginseng stem leaf saponin granule is an ideal Chinese patent drug for improving the immunizing power of the organisms and protecting livers of beasts and birds.