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About Platelet Aggregation Inhibition: Platelet Aggregation Inhibitors decrease platelet aggregation and inhibit thrombus formation. They are effective in the arterial circulation, where anticoagulants have little effect. They are widely used in primary and secondary prevention of thrombotic cerebrovascular or cardiovascular disease.
2-phenylpyrimidine platelet aggregation inhibitors and processes and uses thereof
This invention relates to 2-phenylpyrimidine platelet aggregation inhibitors, their preparation methods, and their application in the preparation of drugs for treating thrombotic diseases, belonging to the field of pharmaceutical technology. The compounds of this invention, their pharmaceutically usable salts, tautomers, and pharmaceutically usable solvates have the structures shown in Formula I, wherein R1-R5 and A are as described in the claims and specification. The compounds of this invention, their pharmaceutically usable salts, tautomers, pharmaceutically usable solvates, and their pharmaceutical compositions have platelet aggregation inhibitory activity and can be used to prepare drugs for the prevention and treatment of thrombotic diseases.
Owner:SHENYANG HINEWY PHARM TECH CO LTD