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Medicament for treating nerve dysfunction after refraining opium type material

A neurological function and opioid technology, applied in the fields of addiction medicine and neurobiology, can solve the problems of restricting the use of traditional Chinese medicine preparations and unclear toxic effects of traditional Chinese medicine, so as to help the body recover, shorten the withdrawal time, and relieve neurological function Effects of Disorder Symptoms

Inactive Publication Date: 2010-08-18
昆明亚灵生物科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, my country has made some progress in TCM detoxification, and has developed several TCM drugs for the treatment of opioid addiction and achieved some success. However, the unclear toxic effects of TCM limit the use of TCM preparations to a certain extent.

Method used

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  • Medicament for treating nerve dysfunction after refraining opium type material
  • Medicament for treating nerve dysfunction after refraining opium type material
  • Medicament for treating nerve dysfunction after refraining opium type material

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Drug formulation:

[0026] Atropine: baclofen (according to mass ratio)=1: 1 (both atropine and baclofen are commercially available products)

[0027] Preparation:

[0028] The analytically pure medicine is respectively dissolved in physiological saline according to atropine:baclofen (according to the mass ratio)=1:1, and mixed uniformly to obtain the compound preparation of the present invention.

Embodiment 2

[0030] Pharmaceutical formula: atropine: baclofen (according to mass ratio)=1:5

[0031] The preparation method is the same as in Example 1.

Embodiment 3

[0033] Drug formulation:

[0034] Atropine: Baclofen (according to mass ratio)=1:10

[0035] The preparation method is the same as in Example 1.

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PUM

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Abstract

The invention relates to a drug for treating the nerve functional disturbance after the withdrawal of opium matters. The drug is a compound preparation which is composed of atropine and baclofen in the mass ratio of 1:1-10. The drug has the main function that the nerve functional disturbance syndrome which is caused by the withdrawal after opioid addiction can be inhibited. The compound preparation can well inhibit the withdrawal syndrome, which is beneficial for the physical recovery. The detoxification drug with the advantages of low use cost, safety, reliability, strong scientificity, and insignificant toxicity and side effects can shorten the withdrawal time relieve or partially remove the nerve functional disturbance syndrome after the withdrawal of the narcotics, and can be used as an ideal detoxification drug.

Description

technical field [0001] The invention relates to the technical fields of addiction medicine and neurobiology, in particular to a medicine for treating neurological dysfunction after opioid withdrawal. technical background [0002] Dependent behavior is a series of cognitive, behavioral, and physiological symptoms produced by addictive substances acting on the susceptible brain. Although the user is very aware of the obvious problems caused by the use of dependent substances, he continues to use them, resulting in Tolerance, dependence symptoms after drug withdrawal and compulsive drug seeking behavior (compulsive drug seeking behavior). Once these symptoms are formed, they persist for a long time. Even after abstinence for several years or even longer, there is still a strong sense of drug craving and the possibility of relapse[1]. Opioids are the most important type of addictive drugs. The use of opioids has brought huge damage to individuals, families, and society, resulti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/46A61K31/195A61P25/30
Inventor 牛海晨马原野
Owner 昆明亚灵生物科技有限公司
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