Composition comprising an extract of combined herb or the processed extract thereof and used for preventing hair loss and treating hair loss, and the use thereof.

A technology for extracts and compositions, applied in the directions of drug combinations, medical preparations containing active ingredients, applications, etc.

CN105963426AInactive Publication Date: 2016-09-28GINSENG SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Publication Date
2016-09-28
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to a composition used for preventing and treating hair baldness and stimulating activity of hair growth; the composition comprises the extract of combined herbs consisting of heat processed ginseng, houttuyniae herba, perilla leaf and tea leaf or the processed extract thereof as active ingredients for preventing and treating hair baldness and stimulating activity of hair growth. The inventive combined extract showed more potent hair-growth promoting activity and synergistic effect than the precedent invention(s), for example, a fermented extract of Houttuyniae Herba, Perilla leaf and Tea leaf disclosed in Korea Patent Publication No, 10-2014-0114492 (A1), through various animal model experiments such as the growth rate test using by C57BL / 6 mouse, the proliferating effect on the growth of HFDPC etc and additionally, more favorable advantage than the precedent invention(s), for example, the easiness in controlling the prescribed dosage by dint of the final form of the inventive extract, i.e., concentrated solid form comparing with the solution type of the final form disclosed in precedent invention.
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Description

technical field

[0001] The present invention relates to a composition containing, as an active ingredient, an extract of mixed herbs consisting of heat-processed ginseng, houttuynia cordata, perilla leaf, and tea leaves or a processed extract thereof, exhibiting hair growth stimulating activity and hair loss preventing activity, and its use. Background technique

[0002] The hair follicle is a very complex organ consisting of the inner root sheath (IRS), outer root sheath (ORS), hair shaft, and hair mother cells (Paus et al., J.Invest.Dermatol., 113, pp523-532, 1999) Among various cells forming hair follicles, dermal papilla cells play an important role in hair growth (Ferraris et al., Exp. Cell Res., 10, pp37-46, 1997).

[0003] Hair follicles develop during embryogenesis through interactions between mesenchymal and epithelial cells. Normal hair growth consists of repeated three phases, namely the anagen (anagen), catagen (catagen) and telogen (telogen) phases (Paus et al...

Examples

Embodiment Construction

[0030] Hereinafter, the present invention will be described in detail.

[0031] Herbal medicines that can be used in the present invention include plants of the same genus that have been used for the same or similar purposes and which can be substituted for disease prevention and treatment, as will be apparent to those skilled in the art.

[0032] The inventive mixed extract of the present invention can be prepared by:

[0033] For example, the inventive inventive extract of the present invention can be prepared by a method comprising the following steps: In step 1, heating ginseng at a high temperature of 80-200°C, preferably at a high temperature of 100-150°C for a period of 0.5-78 hours, A time period of 1-24 hours is preferred so that the ratio of ginsenosides (Rg3+Rg5+Rk1) to (Rb1+Rb2+Rc+Rd) exceeds 1.0 to obtain heat-processed ginseng: In step 2, the heat-processed Panax ginseng, Houttuynia cordata, perilla leaf and tea in the ratio of 1-10:1-10:1-10:1-10(w / w), preferab...