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A traditional Chinese medicine preparation for preventing and treating phlegm-dampness hypertensive type and its preparation method

A technology of traditional Chinese medicine preparations and phlegm dampness, which can be applied to medical formulas, medical preparations containing active ingredients, drug combinations, etc., and can solve problems such as inaccurate clinical efficacy, low safety in use, and unreasonable compatibility structures. Achieve the effect of high application degree of new technology and new process, fill the gap in the market, and mature extraction and separation technology

Active Publication Date: 2020-12-25
SHANDONG ACAD OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of these preparations have problems such as unreasonable compatibility structure, backward preparation technology, inaccurate clinical curative effect, and low safety in use, and the existing varieties are far from meeting the needs of the market. The marketed preparations of the basic formula are applied in clinical practice

Method used

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  • A traditional Chinese medicine preparation for preventing and treating phlegm-dampness hypertensive type and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031]A traditional Chinese medicine preparation for preventing and treating hypertension with excessive phlegm-dampness, which is made from Chinese medicinal active components extracted from Banxia Baizhu Tianma Decoction in the following weight proportions: 18 parts of total saponins; 14.5 parts of total polyphenols.

[0032] A preparation method of a traditional Chinese medicine preparation for preventing and treating phlegm-dampness hypertensive hypertension, which is prepared by the following steps:

[0033] (1) Pinellia Baizhu Tianma Decoction Extraction Extract: Crush the prescription traditional Chinese medicines Pinellia, Atractylodes Rhizoma, Gastrodia elata, Poria cocos, Juhong, and licorice, weigh the coarse powder between 10 and 20 meshes in proportion, extract 3 times respectively, add The amount of water is 10 times, 8 times, and 8 times in turn, and the extraction time is 120min, 90min, and 90min in turn. -1 , 25 min), filtered, combined, and concentrated to ob...

Embodiment 2

[0039] A traditional Chinese medicine preparation for preventing and treating hypertension with excessive phlegm-dampness, which is made from the following active components of traditional Chinese medicine extracted from Banxia Baizhu Tianma Decoction: 25.9 parts of total polysaccharides; 14.5 parts of total polyphenols.

[0040] The preparation method of this Chinese medicine preparation is the same as Example 1.

Embodiment 3

[0042] A traditional Chinese medicine preparation for preventing and treating hypertension with excessive phlegm-dampness is prepared from the following active components of traditional Chinese medicine extracted from Banxia Baizhu Tianma Decoction: 25.9 parts of total polysaccharides; 18 parts of total saponins.

[0043] The preparation method of this Chinese medicine preparation is the same as Example 1.

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Abstract

The invention provides a traditional Chinese medicine preparation for preventing and treating excessive phlegm-dampness type hypertension and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is composed of active components of decoction with rhizoma pinelliae, rhizoma atractylodis macrocephalae and rhizoma gastrodiae as follows: 0-25.9 parts of total polysaccharides, 0-18 parts of total saponins and 0-14.5 parts of total polyphenols. The invention further provides the preparation method of the traditional Chinese medicine preparation, establishes an efficient extraction and refining method suitable for mass production under the premise of ensuring sufficient extraction of the medicinal active components, purifies and refinesthe total polyphenols, the total saponins and the total polysaccharides of six traditional Chinese medicines in the decoction with rhizoma pinelliae, rhizoma atractylodis macrocephalae and rhizoma gastrodiae, and develops an innovative traditional Chinese medicine for preventing and treating excessive phlegm-dampness type hypertension, wherein the novel traditional Chinese medicine has an independent intellectual property right, pharmacodynamic substances and a relatively clear action mechanism.

Description

technical field [0001] The invention belongs to the field of research and development of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine preparation for preventing and treating hypertension with excessive phlegm-dampness and a preparation method thereof. Background technique [0002] Hypertension refers to a systemic disease characterized by increased systemic arterial blood pressure, which may be accompanied by functional or organic changes in multiple organs such as the heart, blood vessels, brain, or kidneys. It is caused by the interaction of polygenic genetic factors and environmental factors. of a disease. According to the "Guiding Principles of Clinical Research of New Chinese Medicines for the Treatment of Hypertension" (Ministry of Health, 1993 Edition), hypertension is divided into hyperactivity of liver fire, hyperactivity of yin and yang, deficiency of both yin and yang, and stagnation of phlegm and dampness. Sheng 4 ty...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8988A61P9/12
CPCA61K36/076A61K36/284A61K36/484A61K36/752A61K36/8888A61K36/8988A61K2236/331A61K2236/39A61K2236/55A61K2300/00
Inventor 徐男时海燕孙蓉
Owner SHANDONG ACAD OF CHINESE MEDICINE
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