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A traditional Chinese medicine hair care liquid formula for enhancing tyrosinase activity

A technology of tyrosinase and hair conditioner, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, hair care, etc.

Active Publication Date: 2022-05-24
福州膳柏健康产业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] There have been reports in the literature on the determination of tyrosinase activity by a single high-concentration alcoholic extract (such as 90% ethanol concentration) of the above-mentioned three medicinal materials. Obtain low-concentration ethanol solution, add transdermal penetration enhancer peppermint oil, constitute the fat-soluble component low-concentration ethanol hair conditioner of the three-flavor medicinal material compound, have not yet been reported

Method used

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  • A traditional Chinese medicine hair care liquid formula for enhancing tyrosinase activity
  • A traditional Chinese medicine hair care liquid formula for enhancing tyrosinase activity
  • A traditional Chinese medicine hair care liquid formula for enhancing tyrosinase activity

Examples

Experimental program
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Effect test

Embodiment 1

[0048] He Shou Wu 90 g Female Virgin 90 g Ginseng 9 g 20% Ethanol 0.3% Peppermint Oil

[0049] Weigh the prescribed amount of He Shou Wu, Female Virgin and Ginseng, mix evenly, use 90% ethanol 5 times the amount of reflux extraction twice, each time for 45min, filter, combine filtrate, concentrate to ethanol concentration remaining 20% solution, add 0.3% peppermint oil, mix evenly, package, that is, solution-type head care solution.

Embodiment 2

[0051] He Shou Wu 90 g Female Virgin 120 g Ginseng 12 g 10% Ethanol 0.4% Peppermint Oil AES to taste

[0052] Weigh the prescribed amount of He Shou Wu, Female Virgin and Ginseng, mix evenly, extract 2 times with 82% ethanol 6 times the amount of reflow, each time for 1.5h, filter, combine filtrate, concentrate to the ethanol concentration of the remaining 15% solution, add 0.4% peppermint oil and an appropriate amount of emulsifier AES, mix evenly, packaging, that is, foam type head care solution.

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Abstract

The invention relates to a formula of traditional Chinese medicine hair conditioner for enhancing the activity of tyrosinase, in particular to the extraction of high-concentration ethanol for the compound of Polygonum multiflorum, Ligustrum lucidum, and ginseng to obtain high-concentration ethanol with low viscosity and high penetration fat-soluble components After the solution, recover the ethanol to a low-concentration ethanol solution, and then add the skin penetration enhancer peppermint oil to form the formula of traditional Chinese medicine hair conditioner. The prepared hair conditioner obviously enhances the activation ability of tyrosinase, and 80% of the The formula reaches 198%, which is significantly greater than the tyrosinase activation ability of the non-sanwei herbal compound, and promotes the effective improvement of black hair function. Applying the Chinese medicine hair conditioner formulation involved in the present invention to the development of hair conditioner for the head, the penetration-promoting skin of the extract will be rapidly improved, and to solve the large first-pass effect of the liver and the biological The problems of low availability, small accumulation concentration of scalp drugs, and weak ability of water-soluble extracts in external preparations to activate tyrosinase provide an effective way.

Description

Technical field [0001] The patent of the present invention belongs to the field of transdermal system of pharmaceutical formulations, specifically relates to a traditional Chinese medicine hair care liquid formulation that enhances the vitality of tyrosinase. Background [0002] The chinese medicine compound of the present invention involves He Shou Wu, Female Virgin and Ginseng Sanwei Herbs together, which has the effect of nourishing the liver and kidneys, black hair hair care. [0003] He Shou Wu is the dried root of he Shou Wu of the Tateshina family, with bitter, sweet, astringent taste, temperate, and returned to the liver, heart and kidney meridians. "Compendium of Materia Medica" said that it can "nourish the blood and benefit the liver, solid lean kidneys, strengthen the muscles and bones, black hair", in the folk prescription, He Shou Wuduo is used for the treatment of premature whitening, hair loss, alopecia areata, etc., and the medicinal agent is emodin, emodin methy...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/92A61Q5/12
CPCA61K8/9789A61K8/922A61Q5/12A61K2800/78A61K2800/805
Inventor 李孝栋曾建伟何怡静
Owner 福州膳柏健康产业有限公司