Anti-dandruff itching-relieving acarus-killing shampoo composition and preparation method thereof

Abstract

The invention relates to a shampoo composition, in particular to an anti-dandruff, itching-relieving and acarus-killing shampoo composition and a preparation method thereof. The shampoo composition comprises a plant extract, a surfactant, a humectant, an emollient, a thickening agent, a pH regulator, a chelating agent, essence, a preservative and water. The composition prepared by the invention is good in dandruff-removing and itching-relieving effects and excellent in mite-removing effect, can moisturize scalp and endow the scalp with a moistening effect, and also has relatively good storage stability.

Description

Technical Field

[0001] The invention relates to a shampoo composition, in particular to an anti-dandruff, anti-itching and anti-mite shampoo composition and a preparation method thereof. Background Art

[0002] The basic ingredients of shampoo are surfactants, which can effectively clean excess oil, dust and other dirt on the scalp and hair. Different types of shampoos have different scalp care effects. For example, moisturizing shampoo can deeply moisturize the scalp and is suitable for dry scalp; oil-control shampoo can adjust the oil balance of the scalp and is suitable for oily scalp; shampoo with added anti-dandruff ingredients can effectively control the production of dandruff and relieve symptoms such as itchy scalp; added conditioning agents, such as cationic guar gum and emulsified silicone oil, can provide care and protection for the hair while washing, making the hair soft and easy to comb.

[0003] Although there are many types of shampoo products currently, it is difficult for shampoo products on the market to have multiple functions and maintain good effects. Therefore, providing a shampoo composition that has good anti-dandruff and antipruritic effects, excellent mite removal effects, and can also moisturize the scalp, provide scalp moisture, and is stable in storage is one of the technical problems that need to be solved. Summary of the invention

[0004] The present invention aims at the above technical problems and proposes a technical solution of the present invention, which includes an anti-dandruff, anti-itching and anti-mite shampoo composition and a preparation method thereof.

[0005] The shampoo composition obtained by the scheme of the present invention has good anti-dandruff and antipruritic effects, excellent mite removal effects, and can also moisturize the scalp and provide moisture to the scalp, and is relatively stable in storage.

[0006] The specific scheme of the present invention is as follows:

[0007] The invention discloses an anti-dandruff, antipruritic and anti-mite shampoo composition, which comprises the following raw materials in percentage by mass: 0.4-5.5% of plant extract, 8-20% of surfactant, 3-6% of moisturizer, 4-10% of emollient, 0.5-2.8% of thickener, 0.2-1% of pH regulator, 0.1-1% of chelating agent, 0.001-0.5% of essence, 0.08-0.4% of preservative and the balance of water.

[0008] Furthermore, the plant extract composition is: 0.05-0.8% Cordyceps militaris extract, 0.08-1% Black Ganoderma lucidum extract, 0.05-0.6% Sage extract, 0.07-1% Norway spruce extract, 0.1-0.8% Aloe vera extract, 0.1-0.5% Licorice extract, 0.05-0.8% Algae extract; the combination is used as the basis.

[0009] Furthermore, the dosage of the Cordyceps militaris extract can also be 0.1%, 0.12%, 0.15%, 0.2%, 0.25%, 0.4%, 0.5%, or 0.8%.

[0010] Furthermore, the dosage of the black ganoderma extract can also be 0.1%, 0.12%, 0.15%, 0.2%, 0.25%, 0.4%, 0.5%, 0.8%, or 0.1%.

[0011] Furthermore, the dosage of the sage extract can be 0.1%, 0.12%, 0.15%, 0.2%, 0.25%, 0.4%, 0.5%, or 0.6%.

[0012] Furthermore, the Norway spruce extract can be used in an amount of 0.1%, 0.12%, 0.15%, 0.2%, 0.25%, 0.4%, 0.5%, 0.6%, 0.7%, or 1%.

[0013] Furthermore, the amount of the aloe extract can be 0.1%, 0.12%, 0.15%, 0.2%, 0.25%, 0.4%, 0.5%, 0.6%, 0.7%, or 0.8%.

[0014] Furthermore, the amount of the aloe extract can be 0.1%, 0.12%, 0.15%, 0.2%, 0.25%, 0.4%, 0.5%, 0.6%, 0.7%, or 0.8%.

[0015] Further, the surfactant composition is: 0.5-4% cetearyl alcohol polyether, 0.5-3% Tween-60, 3-5% sodium lauroyl glutamate, 2-4% sodium cocoyl glycinate and 2-4% sodium palmitoyl glycinate, with the composition as the basis.

[0016] Furthermore, the emollient is at least one of isopropyl myristate, cetyl lactate, myristyl lactate, trimyristinyl glycerol, camellia seed oil, grape seed oil, squalane, and evening primrose oil.

[0017] Furthermore, the moisturizing agent is at least one of polyols, dextran, hyaluronic acid and salts thereof.

[0018] Furthermore, the thickener is at least one of polyacrylate, acrylic acid copolymer, carboxymethyl cellulose and vegetable gum.

[0019] Furthermore, the pH adjuster includes at least one of lactic acid, tartaric acid and citric acid.

[0020] Furthermore, the chelating agent includes at least one of citrate, EDTA and its salts, aminopolycarboxylic acid and its salts.

[0021] Furthermore, the mass ratio of the sage extract to the Norway spruce extract is 1:1.5-2.4, 1:1.6-2.3, 1:1.7-2.2. Furthermore, the mass ratio of the porphyra extract to the aloe extract is 1:0.5-1, 1:0.55-0.9, 1:0.6-0.9.

[0022] On the other hand, the present invention also provides a method for preparing the composition, comprising the following steps:

[0023] Add water into the reaction container, heat and start stirring, add moisturizer and surfactant, and stir evenly; then add emollient and thickener and stir evenly; cool down, continue to add plant extract, pH adjuster, chelating agent, preservative and flavor, stir evenly to obtain the composition.

[0024] Furthermore, the heating temperature is 50-68°C, and the cooling temperature is 15-30°C.

[0025] Furthermore, the rotation speed during the stirring process is 50-1000 rpm, and the stirring time can be conventionally selected in combination with the need for uniform stirring.

[0026] Beneficial effects of the present invention:

[0027] The present invention uses plant extracts, surfactants, moisturizers, emollients, thickeners, pH regulators, chelating agents, essences, preservatives and water to prepare a shampoo composition which has good anti-dandruff and antipruritic effects, excellent mite removal effects, can also moisturize the scalp, provide scalp moisture, and has good storage stability.

[0028] The composition of the present invention has a good mite removal effect. The combination of sage extract and Norway spruce extract used in the present invention can significantly improve the mite removal effect of the composition. The two have a mutually reinforcing relationship in improving the mite removal effect. The combination of the two extracts makes the types of mite removal active ingredients produce a combined complementary relationship, which can further promote the mite killing effect. When the mass ratio of the sage extract and the Norway spruce extract used in the composition reaches a range of 1:1.5-2.4, the mite removal effect of the product is better.

[0029] The composition prepared by the present invention has a good moisturizing effect; it can increase the skin moisture content by 54.95% after 4 hours of use, and by 22.54% after 10 hours of use. The present invention uses the compound of the porphyra algae extract and the aloe extract to significantly improve the moisturizing effect of the composition. The combination of the two produces a compound relationship, so that the composition of the present invention has a good moisturizing effect on the skin.

[0030] The product of the invention has excellent stability, can withstand low and high temperatures without stratification and precipitation, and has a highly effective anti-dandruff and antipruritic effect. DETAILED DESCRIPTION

[0031] The present invention will be described below in conjunction with specific embodiments, and various effects of the present invention will be more clearly presented. It should be understood by those skilled in the art that these specific embodiments are used to illustrate the present invention, rather than to limit the present invention.

[0032] Unless otherwise specified, various raw materials, reagents, instruments and equipment used in the present invention can be purchased from the market or prepared by existing methods.

[0033] Raw material preparation:

[0034] Cordyceps militaris extract: Crush the dried Cordyceps militaris, add 20 times the mass of 24.5% ethanol aqueous solution by volume, stir at 65°C and 60rpm for 8 hours, filter with a 2μm pore size filter membrane, and ultrafilter the filtrate with an ultrafiltration membrane with a molecular weight cutoff of 2000Da. Concentrate the ultrafiltrate and freeze-dry it to a water content of about 5.27wt% to obtain the extract.

[0035] Black Ganoderma Lucidum Extract: Crush dried Cordyceps militaris, add 50 times the weight of water, boil at 85°C for 5 hours, filter through a 1 μm pore size filter membrane, ultrafilter the filtrate through an ultrafiltration membrane with a molecular weight cutoff of 1800 Da, concentrate the ultrafiltrate, and freeze-dry to a water content of about 6.03 wt%, to obtain the extract.

[0036] Sage extract: Crush the dried sage, add 30 times the mass of 35% ethanol aqueous solution by volume, stir at 55°C and 50rpm for 6.4 hours, filter with a 0.5μm pore size filter membrane, and ultrafilter the filtrate with an ultrafiltration membrane with a molecular weight cutoff of 1000Da. Concentrate the ultrafiltrate and freeze-dry it to a water content of about 5.78wt% to obtain the extract.

[0037] Norway spruce extract: Dried Norway spruce leaves are crushed, and a 40% ethanol aqueous solution with a volume concentration of 28 times the mass is added, stirred at 52° C. and 70 rpm for 7 hours, filtered through a 2 μm pore size filter membrane, and the filtrate is ultrafiltered through an ultrafiltration membrane with a molecular weight cutoff of 1500 Da. The ultrafiltrate is concentrated and freeze-dried to a water content of about 5.91 wt% to obtain the extract.

[0038] Extract of Algae: The dried Algae is crushed, 60 times the weight of water is added, and the mixture is boiled at 70° C. for 4.2 hours. The mixture is filtered through a 5 μm pore size filter membrane, and the filtrate is concentrated and freeze-dried to a water content of about 6.42 wt %, to obtain the extract.

[0039] Licorice extract: Crush dried Norway spruce leaves, add 37 times the mass of a 15% ethanol aqueous solution by volume, stir at 45°C and 70rpm for 8 hours, filter with a 2μm pore size filter membrane, and ultrafilter the filtrate with an ultrafiltration membrane with a molecular weight cutoff of 1300Da. Concentrate the ultrafiltrate and freeze-dry it to a water content of about 4.25wt% to obtain the extract.

[0040] Aloe extract: Crush dried Cordyceps militaris, add 50 times the weight of water, boil at 68° C. for 5 hours, filter with a 5 μm pore size filter membrane, concentrate the filtrate, and freeze-dry to a water content of about 5.36 wt %, to obtain the extract.

[0041] Preparation Example 1:

[0042] Preparation raw materials: 0.6% Cordyceps militaris extract, 0.7% Black Ganoderma lucidum extract, 0.4% Sage extract, 0.8% Norway spruce extract, 0.5% Hole leaf algae extract, 0.2 Licorice extract, 0.4% Aloe extract, 3.5% Cetearyl alcohol polyether, 2.5% Tween-60, 4% Sodium lauroyl glutamate, 3.5% Sodium cocoyl glycinate, 3.5% Sodium palmitoyl glycinate, 1% glycerin, 1% 1,2-propylene glycol, 1.5% β-glucan, 1% sorbitol, 2% Camellia seed oil, 1.5% Grape seed oil, 1.5% Squalane, 2% Evening primrose oil, 1.3% thickener Carbomer-941, 0.6% pH adjuster citric acid, 0.45% chelating agent EDTA-2Na, 0.02% lemon essence, 0.3% preservative phenoxyethanol and the balance water.

[0043] The mass ratio of the sage extract to the Norway spruce extract is 1:2. The mass ratio of the porphyra extract to the aloe vera extract is 1:0.8.

[0044] Preparation method: add water to a reaction container, heat to 60°C and start stirring, add a moisturizer and a surfactant, stir at 70 rpm for 0.5 hour, and stir evenly; then add an emollient and a thickener, keep stirring at 70 rpm for 0.4 hour, and stir evenly; cool to 25°C, continue to add plant extracts, pH adjusters, chelating agents, preservatives and flavors, stir at 70 rpm for 0.4 hour, and stir evenly to obtain the composition of Preparation Example 1.

[0045] Preparation Example 2:

[0046] Preparation materials: 0.5% Cordyceps militaris extract, 0.8% Black Ganoderma lucidum extract, 0.45% Sage extract, 0.75% Norway spruce extract, 0.45% Cone leaf algae extract, 0.15% Licorice extract, 0.45% Aloe extract, 3% Cetearyl alcohol polyether, 1% Tween-60, 5% Sodium lauroyl glutamate, 4% Sodium cocoyl glycinate, 3.5% Sodium palmitoyl glycinate, 0.5% Glycerin, 1.5% 1,2-propylene glycol, 1.2% β-glucan, 1.3% sorbitol, 2.5% camellia seed oil, 1.2% grape seed oil, 2% squalane, 1.5% evening primrose oil, 1.27% thickener carbomer-941, 0.55% pH adjuster citric acid, 0.4% chelating agent EDTA-2Na, 0.015% lemon essence, 0.35% preservative phenoxyethanol and the rest water.

[0047] The mass ratio of the sage extract to the Norway spruce extract is 1:67. The mass ratio of the porphyra extract to the aloe vera extract is 1:1.

[0048] Preparation method: add water to a reaction container, heat to 550°C and start stirring, add a moisturizer and a surfactant, stir at 80 rpm for 0.6 hours, and stir evenly; then add an emollient and a thickener, stir at 80 rpm for 0.5 hours, and stir evenly; cool to 20°C, continue to add plant extracts, pH adjusters, chelating agents, preservatives and flavors, stir at 60 rpm for 0.5 hours, and stir evenly to obtain the composition of Preparation Example 2.

[0049] Preparation Example 3: Compared with Preparation Example 1, the extract of sage and Norway spruce is not contained, water is used to make up, and the other contents are the same as Preparation Example 1.

[0050] Preparation Example 4: Compared with Preparation Example 1, which does not contain sage extract, the amount of Norway spruce extract is adjusted to 1.2%, and the rest is the same as Preparation Example 1.

[0051] Preparation Example 5: Compared with Preparation Example 1, which does not contain Norway spruce extract, the amount of sage extract is adjusted to 1.2%, and the rest is the same as Preparation Example 1.

[0052] Preparation Example 6: The difference compared to Preparation Example 1 is that 0.15% sage extract and 1.05% Norway spruce extract are used in a ratio of 1:7. The rest is the same as Preparation Example 1.

[0053] Preparation Example 7: The difference compared to Preparation Example 1 is that 0.7% sage extract and 0.5% Norway spruce extract are used, and the ratio of the two is 1:0.71. The rest is the same as Preparation Example 1.

[0054] Preparation Example 8: Compared with Preparation Example 1, the extract of Algae porphyrae and Aloe vera is not contained, and water is used to make up the extract. Other contents are the same as Preparation Example 1.

[0055] Preparation Example 9: Compared with Preparation Example 1, the extract of Aloe vera was not contained, and the amount of Aloe vera extract was adjusted to 0.9%, which was supplemented with water. The rest was the same as Preparation Example 1.

[0056] Preparation Example 10: Compared with Preparation Example 1, which does not contain aloe extract, the amount of the porphyra extract is adjusted to 0.9%, which is supplemented with water. Others are the same as Preparation Example 1.

[0057] Effect test

[0058] 1. Mite removal effect test

[0059] The mite killing test was conducted with reference to the standard NY / T 1151.2-2006 to test the mite killing efficiency for 24 hours; the number of mites in each test group was 1000, and each group was tested three times in parallel; the test sample was obtained by diluting the product in the above preparation example with water 15 times, and the test mite species were Demodex and Dermatophagoides farinae. The specific test results are shown in Table 1.

[0060] Table 1: Mite removal effect test

[0061]

[0062] Preparation Example 1 98.7 97.8 Preparation Example 2 98.2 97.3 Preparation Example 3 61.6 59.4 Preparation Example 4 90.2 89.1 Preparation Example 5 92.5 91.4 Preparation Example 6 96.1 95.1 Preparation Example 7 94.7 93.7 Preparation Example 8 85.4 84.2 Preparation Example 9 97.5 95.6 Preparation Example 10 98.4 97.5

[0063] It can be seen from the test results in Table 1 that the composition of the present invention has a good mite removal effect. The combination of sage extract and Norway spruce extract used in the present invention can significantly improve the mite removal effect of the composition. The two have a mutually reinforcing relationship in improving the mite removal effect. The possible reason is that the combination of the two extracts makes the types of mite removal active ingredients produce a combined complementary relationship, which can further promote the mite killing effect. And when the mass ratio of the sage extract and the Norway spruce extract used in the composition reaches the range of 1:1.5-2.4, the mite removal effect of the product is better.

[0064] 2. Moisturizing effect test

[0065] Volunteers aged 30-40 were selected and randomly divided into 8 groups according to age, with 3 male and female members in each group. The volunteers selected the same skin area of ​​3*3 cm on the inner side of the arm as the test area. Each group of volunteers used 0.2g of the above-mentioned preparation example product on the test area. The skin moisture content before, 4 hours after and 10 hours after using the preparation example product was measured using CK Company's Corneometer CM 825, and the increase rate of moisture content at different times after using the product compared to before using the sample was calculated. The results are shown in Table 2.

[0066] Table 2: Moisturizing effect test

[0067]

[0068] It can be seen from the test results in Table 2 that the composition prepared by the present invention using plant extracts, surfactants, moisturizers, emollients, thickeners, pH adjusters, chelating agents, essences, preservatives and water has a good moisturizing effect; the skin moisture content can be increased by 54.95% after 4 hours of use, and the skin moisture content can be increased by 22.54% after 10 hours of use. It can be seen from the test results of Preparation Examples 1, 8-10 that the present invention uses the compounding of the porphyra extract and the aloe extract to significantly improve the moisturizing effect of the composition, and the combination of the two produces a compound relationship, so that the composition of the present invention has a good moisturizing effect on the skin.

[0069] 3. Stability effect test

[0070] Low temperature resistance test: -10℃ constant temperature box for 24 hours, take out, naturally heat to room temperature, and observe whether the product has stratification and precipitation. High temperature stability: 40℃ constant temperature box for 24 hours, take out, naturally cool to room temperature, and observe whether the product has stratification and precipitation. The test results are shown in Table 3.

[0071] Table 3: Stability effect test

[0072] Stability test Low temperature resistance High temperature resistance Preparation Example 1 No stratification, no precipitation No stratification, no precipitation Preparation Example 2 No stratification, no precipitation No stratification, no precipitation Preparation Example 3 No stratification, no precipitation No stratification, no precipitation Preparation Example 4 No stratification, no precipitation No stratification, no precipitation Preparation Example 5 No stratification, no precipitation No stratification, no precipitation Preparation Example 6 No stratification, no precipitation No stratification, no precipitation Preparation Example 7 No stratification, no precipitation No stratification, no precipitation Preparation Example 8 No stratification, no precipitation No stratification, no precipitation Preparation Example 9 No stratification, no precipitation No stratification, no precipitation Preparation Example 10 No stratification, no precipitation No stratification, no precipitation

[0073] It can be seen from Table 3 that the product of the present invention has excellent stability and can withstand low and high temperatures without stratification or precipitation.

[0074] 4. Anti-dandruff and anti-itching effect test

[0075] 40 male volunteers with dandruff and itchy scalp, aged between 20 and 30 years old, were selected and randomly divided into 2 groups, 20 in each group. They used the above-mentioned preparation product once every two days for shampooing for four weeks. The hair condition was observed and scored 8 hours after the last shampooing. The scoring criteria are shown in Table 4.

[0076] Table 4: Scoring criteria

[0077] grade Evaluation Criteria invalid Dandruff and itching did not improve or worsen efficient Dandruff and itching have improved Significant Significant reduction in dandruff and itching

[0078] The test results are shown in Table 5.

[0079] Table 5: Anti-dandruff and anti-itching effect test

[0080]

[0081] It can be seen from the test in Table 5 that the composition of the present invention has excellent anti-dandruff and antipruritic effects.

[0082] Obviously, those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include these modifications and variations.

Claims

1. A shampoo composition for removing dandruff, antipruritic and mite removing, characterized in that: According to mass percentage, the raw material composition is: 0.4-5.5% plant extract, 8-20% surfactant, 3-6% moisturizer, 4-10% emollient, 0.5-2.8% thickener, 0.2-1% pH adjuster, 0.1-1% chelating agent, 0.001-0.5% flavor, 0.08-0.4% preservative and balance water.

2. The composition according to claim 1, characterized in that The plant extract comprises: 0.05-0.8% cordyceps militaris extract, 0.08-1% black ganoderma lucidum extract, 0.05-0.6% sage extract, 0.07-1% Norway spruce extract, 0.1-0.8% aloe extract, 0.1-0.5% liquorice extract and 0.05-0.8% porphyra extract.

3. The composition according to claim 1, characterized in that The surfactant composition is: 0.5-4% Ceteareth, 0.5-3% Tween-60, 3-5% Sodium Lauroyl Glutamate, 2-4% Sodium Cocoyl Glycinate, and 2-4% Sodium Palmitoyl Glycinate.

4. The composition according to claim 1, characterized in that The emollient is at least one of isopropyl myristate, cetyl lactate, myristyl lactate, trimyristinyl glycerol, squalane, camellia seed oil, grape seed oil and evening primrose oil.

5. The composition according to claim 1, characterized in that The moisturizing agent is at least one of polyol, dextran, hyaluronic acid and salts thereof.

6. The composition according to claim 1, characterized in that The thickener is at least one of polyacrylate, acrylic acid copolymer, carboxymethyl cellulose and vegetable gum.

7. The composition according to claim 1, characterized in that The pH adjuster includes at least one of lactic acid, tartaric acid and citric acid.

8. The composition according to claim 1, characterized in that The chelating agent includes at least one of citrate, EDTA and its salts, aminopolycarboxylic acid and its salts; the mass ratio of the sage extract to the Norway spruce extract is 1:1.5-2.4; the mass ratio of the porphyra extract to the aloe extract is 1:0.5-1.

9. A method for preparing the composition according to any one of claims 1 to 8, characterized in that: The steps include: Add water into the reaction container, heat and start stirring, add moisturizer and surfactant, and stir evenly; then add emollient and thickener and stir evenly; cool down, continue to add plant extract, pH adjuster, chelating agent, preservative and flavor, stir evenly to obtain the composition.

10. The preparation method according to claim 9, characterized in that The heating temperature is 50-68℃, and the cooling temperature is 15-30℃.

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