Liver-protecting health-care tea

Abstract

The liver-protecting health-care tea comprises 20 parts of Pu'er tea, 10 parts of centella asiatica leaves, 10 parts of nutgall, 20 parts of dried longan, 10 parts of chrysanthemum, 10 parts of penthorum chinense pursh, 10 parts of dendrobe and 10 parts of Chinese dates. The tea is prepared into tea bags, and each bag is 30g. The traditional Chinese medicine composition is simple in process and low in cost, has a remarkable treatment effect on acute and chronic hepatitis, cholestatic hepatitis, alcoholic hepatitis, fatty liver and the like, and also has the effects of clearing fat, losing weight, inducing diuresis, promoting alcohol metabolism, protecting liver after drinking and the like; the liver health tea bag provided by the invention is rich in nutritional ingredients, very convenient to drink for a long time, high in appearance grade, convenient to use, strong, mellow, sweet and fragrant in taste and worthy of being well developed and utilized, and the products are placed in the tea bag in proportion.

Description

Technical Field

[0001] The invention relates to the field of health-care foods, and in particular to a liver-protecting health-care tea. Background Art

[0002] The liver is an important organ of higher animals. Its metabolism is very active and is closely related to the life, health, growth and development of the body. The liver has a wide range of physiological functions, such as the production of fibrinolytic factors, detoxification and excretion, bile secretion, immunity, coagulation, biological metabolism and transformation. However, the liver is the most sensitive and fragile organ. Bad living habits such as lack of sleep, obesity, high blood sugar, excessive drinking, smoking, staying up late, drug abuse, greasy food, etc. will increase the burden on the liver and damage the liver, and then develop into chronic hepatitis, alcoholic fatty liver, non-alcoholic fatty liver, chronic liver damage and other liver diseases, and even develop into liver cancer. Once the liver's metabolic function is impaired, it often affects other organs, which can easily lead to symptoms such as low immune function, material conversion dysfunction, poor coagulation, and bile secretion and excretion disorders, which in turn cause systemic organ dysfunction and seriously affect growth, development and health. Therefore, protecting the liver is of great significance for preventing and treating diseases and ensuring the health of the body.

[0003] There are many kinds of liver protection products on the market, and Chinese medicine liver protection is one of them. Chinese medicine for liver protection has the advantages of less residue, mild toxic side effects, and not easy to form drug resistance; and Chinese medicine has the characteristics of wide sources and can be used as medicine and food at the same time, and its effect is widely recognized by the public. The multiple components of Chinese medicine determine that Chinese medicine for liver protection has the characteristics of multi-target, multi-faceted comprehensive prevention and treatment effects. Among them, polysaccharides, glycosides, sterols and other effective ingredients in Chinese medicine have good protective effects on the liver. Finding compound Chinese medicine health tea with liver protection effect and strengthening daily health care are of great significance to the prevention of liver disease.

[0004] Pu'er tea is cold in nature and slightly bitter in taste. It enters the bladder meridian and mainly contains calcium sulfate, flavonoids, volatile oils, saponins, pentose, glucuronic acid, and calcium and potassium salts of various organic acids. It has the functions of clearing away heat and detoxification, antibacterial and stranguric acid, anti-inflammatory and swelling, stone removal and diuresis, and inhibiting chronic renal failure.

[0005] Centella asiatica: bitter, pungent, cold. It has the effects of clearing away heat and dampness, detoxifying and reducing swelling. It is often used for damp-heat jaundice, heatstroke diarrhea, stone stranguria, carbuncle, sore, and injury from falls. Gallic acid: bitter in taste, warm in nature. It enters the lung, spleen, and kidney meridians. It has the effects of astringing the intestines, consolidating essence, relieving cough, stopping bleeding, and astringing sores. Longan: It controls the evil spirits of the five internal organs, calms the mind, and relieves anorexia. Long-term use strengthens the soul. It has the effects of anti-aging, anti-cancer, immune regulation, and promoting intellectual development. Chrysanthemum: pungent, sweet, bitter, slightly cold. It enters the lung and liver meridians. The main effects are to evacuate wind-heat, calm liver yang, clear the liver and improve eyesight, clear heat and detoxify. It is used to treat wind-heat colds, early onset of febrile diseases, hyperactivity of liver yang, headache and dizziness, red and swollen eyes, blurred vision, sores, carbuncle, and sore. Herba scutellariae: sweet and warm. It enters the liver and kidney meridians. It promotes diuresis and removes dampness, removes blood stasis and relieves pain. Dendrobium: cold in nature, sweet, light, slightly salty in taste. Nourishes yin, clears heat, promotes the production of body fluids and quenches thirst. Used for damage to body fluids due to febrile diseases, thirst and dry tongue, post-illness heat, stomach problems, retching, and a pale tongue with little coating. Jujube: sweet, warm. Nourishes the spleen and harmonizes the stomach, replenishes qi and promotes the production of body fluids, regulates the Ying and Wei, and detoxifies drugs. Treats poor appetite due to deficiency of the stomach, loose stools due to weak spleen, insufficient qi, blood and body fluids, disharmony between Ying and Wei, and palpitations. It can also cause impotence in women.

[0006] The purpose of the present invention is to provide a liver protection health tea, which is prepared from natural raw materials, has a simple process, and the effective health care ingredients are not destroyed. The product has a high medical and health care value and is easily accepted by most people. Summary of the invention

[0007] The present invention is achieved by the following technical means:

[0008] The present invention first discloses a liver protection health tea, comprising:

[0009] 20 parts of Pu'er tea, 10 parts of Centella asiatica leaves, 10 parts of gallic acid seeds, 20 parts of dried longans, 10 parts of chrysanthemums, 10 parts of yellow grass, 10 parts of dendrobiums, and 10 parts of jujubes.

[0010] Furthermore, the Pu'er tea is Pu'er cooked tea.

[0011] Furthermore, the Pu'er tea is dried at 90-120° C. for 20-30 minutes.

[0012] Furthermore, the Centella asiatica leaves are dried at 90-120° C. for 20-30 minutes.

[0013] Furthermore, the gallic acid is obtained by drying at 90-120° C. for 20-30 minutes.

[0014] Furthermore, the dried longan is prepared by the following method: fresh longan is dried at 90-120° C. for 24 hours, and the core is removed and the fruit is retained.

[0015] Furthermore, the chrysanthemum is prepared by the following method: fresh chrysanthemum is dried at 90-120° C. for 24 hours.

[0016] Furthermore, the yellow grass is the rhizome of the yellow grass, which is prepared by the following method: the rhizome of the yellow grass is dried at 90-120° C. for 20-30 minutes.

[0017] Furthermore, the dendrobium is the stem of dendrobium, which is obtained by the following method: the stem of dendrobium is dried at 90-120° C. for 20-30 minutes.

[0018] Furthermore, the jujube is prepared by the following method: fresh jujube is dried at 90-120° C. for 24 hours, pitted and sliced.

[0019] The liver protection health tea provided by the invention is prepared by obtaining dried products of Pu'er cooked tea, Centella asiatica leaves, gallic acid seeds, dried longan, chrysanthemum, radix scutellariae, dendrobium and jujube according to a conventional method, and then mixing the extracts according to the above proportions and putting them into a tea bag. The tea bag or small can tea can be packaged.

[0020] The beneficial effects of the present invention are:

[0021] 1. The process of the present invention is simple and the cost is low. The product has a significant therapeutic effect on cholestatic liver damage and fatty liver. It can also protect liver function, promote alcohol metabolism, and protect the liver after drinking.

[0022] 2. The liver protection health tea provided by the present invention has a significant therapeutic effect on cholestatic liver damage, fatty liver, etc., and can also protect liver function, promote alcohol metabolism, and protect the liver after drinking. The provided liver protection health tea bag is rich in nutrients and is very convenient for long-term drinking. The product is placed in the tea bag according to proportion, has a high-grade appearance, is easy to use, has a rich and mellow taste, and is sweet and fragrant, and is worthy of good development and utilization. DETAILED DESCRIPTION

[0023] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below in combination with the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0024] Example 1

[0025] The Pu'er cooked tea is processed by conventional methods by weight. 20 parts of Pu'er cooked tea are dried at 90-120℃ for 20-30min; 10 parts of Centella asiatica are dried at 90-120℃ for 20-30min; 10 parts of Gallic acid are dried at 90-120℃ for 20-30min; 20 parts of dried longan are fresh longan dried at 90-120℃ for 24h, and the core is removed and the fruit is kept. 10 parts of chrysanthemum are fresh chrysanthemum dried at 90-120℃ for 24h; 10 parts of chrysanthemum are stems and leaves of chrysanthemum, dried at 90-120℃ for 20-30min; 10 parts of Dendrobium are stems of Dendrobium, dried at 90-120℃ for 20-30min; 10 parts of jujube are fresh jujube dried at 90-120℃ for 24h, and the core is removed and sliced. The ingredients are mixed with the prepared Pu'er cooked tea to obtain a liver-protecting health tea, which can be packaged in the form of tea bags or small cans.

[0026] Test Example 1

[0027] 1 Materials and methods

[0028] 1.1 Trial Drugs

[0029] Formula 1: 20 parts of Pu'er tea, 10 parts of Centella asiatica leaves, 10 parts of gallic acid fruits, 20 parts of dried longan, 10 parts of chrysanthemum, 10 parts of yellow grass, 10 parts of dendrobium, and 10 parts of jujube (i.e., Example 1 of the present invention).

[0030] Recipe 2: 10 parts of Pu'er tea, 5 parts of Centella asiatica leaves, 5 parts of gallic acid, 5 parts of dried longan, 5 parts of chrysanthemum, 5 parts of yellow grass, 5 parts of dendrobium, and 5 parts of jujube.

[0031] Recipe 3: 20 parts of Pu'er tea, 20 parts of dried longan, 10 parts of chrysanthemum, 10 parts of yellow grass, 10 parts of dendrobium, and 10 parts of jujube.

[0032] The above Chinese medicine raw materials are washed, dried, crushed and prepared into Chinese medicine stock solution according to the conventional decoction method, with a concentration of 0.2mL / g (each milliliter is equivalent to 0.2g of original medicinal material), and stored in a refrigerator at 0-4℃ for future use.

[0033] Positive control drug 1: Chaihu Shugan San

[0034] Positive control drug 2: Silybin meglumine tablets

[0035] Positive control drug 3: Simvastatin

[0036] 1.2 Experimental animals

[0037] SD rats, male, 130, (200±20)g, SPF grade

[0038] 1.3 Test methods

[0039] 1.3.1α-Naphthalene isothiocyanate (ANIT)-induced cholestatic liver injury model

[0040] SD rats, male, 70. They were randomly divided into negative control group, model group, test group 1-3, positive control group 1, and positive control group 2 according to body weight. The negative control group and model group were given an equal amount of purified water every day, and the animals in test groups 1-3 were gavaged with the original solution of formula 1-3 at 10 mL / kg body weight every day; the animals in positive control group 1 were gavaged with positive control drug 1 at a concentration of 0.5 g / mL at 10 mL / kg body weight every day; the animals in positive control group 2 were gavaged with positive control drug 2 (drug dose of 5 mg / kg); the animals in each group were given the drug once a day for 10 consecutive days; the animals in each group were gavaged with 10 mg / ml ANIT oil solution at 100 mg / kg body weight on the 4th and 8th days of administration to prepare the cholestatic liver injury model, and the rats in the negative control group were not modeled. After modeling, the mice were fasted but not watered. Two days later, blood was collected from the orbital venous plexus after ether anesthesia to determine serum ALT, AST, ALP, and TBA levels. Liver tissue was taken to detect liver tissue SOD, MDA, and GSH levels.

[0041] 1.3.2 High-fat diet-induced fatty liver rat model

[0042] SD rats, male, 60. They were randomly divided into 2 groups according to body weight by random number method, 10 rats were given maintenance feed as negative control group, and 50 rats were given model feed as model group; after feeding for 2 weeks, the model group was randomly divided into 7 groups according to serum total cholesterol (TC) level by random number method, namely model group (no drug administration), positive control group (positive control drug 3, the dosage was 3mg / kg), test group 1-3 (the original solution of formula 1-3, each group of animals was gavaged with the corresponding drug at 10mL / kg body weight every day), 10 rats in each group, after grouping, the drug was administered once a day for 30 consecutive days. The negative control group continued to be given maintenance feed, and the other groups continued to be given model feed. At the end of the experiment, blood was collected from the inner canthus of the eye after ether anesthesia without fasting, and serum TC, TG, LDL-C, and HDL-C were measured; after blood collection and killing, the liver was quickly cut open and washed with saline and filtered with filter paper to dry the blood, the liver weight was weighed, and the liver coefficient was calculated (100g rat body weight contains g weight of liver).

[0043] 2 Results and analysis

[0044] 2.1 Effects of different formulas of stock solutions and positive control drugs on cholestatic liver injury

[0045] As shown in Table 1, compared with the negative control group, the serum ALT, AST, ALP, TBA, and MDA levels in the model group increased significantly (P<0.05); compared with the model group, the serum levels of test groups 1-3 and positive control groups 1-2 decreased significantly (P<0.01). In liver tissue, compared with the negative control group, the SOD and GSH levels in the liver tissue of the model group decreased significantly (P<0.05), and the liver tissue indicators of the other groups increased compared with the model group, with significant differences (P<0.05).

[0046] Table 1 Effects of different formulas of stock solutions and positive control drugs on serum indicators of cholestatic liver injury induced by α-naphthalene isothiocyanate (ANIT)

[0047]

[0048]

[0049] Note: Compared with the model group, the negative control group * P<0.05, model group compared with each drug group ▲ P<0.05, ▲▲ P<0.01, the same below.

[0050] 2.2 Effects of different formulas of stock solutions and positive control drugs on high-fat diet-induced fatty liver in rats

[0051] As shown in Table 2, two weeks after modeling, compared with the negative control group, the serum TC, TG, and LDL-C levels of each group increased significantly, and the serum HDL-C decreased significantly (P<0.01); compared with the model group, the serum TC and TG levels of the positive control group and test groups 1-3 decreased significantly (P<0.05), and the serum LDLC levels of test groups 1-3 decreased significantly (P<0.05). Compared with the model group, the liver coefficients of each group decreased, and the positive control group and test groups 1-2 decreased significantly (P<0.05).

[0052] Table 2 Effects of different formulas of stock solutions and positive control drugs on high-fat diet-induced fatty liver rat model

[0053]

[0054] The stock solutions of formulas 1-3 and the positive control drugs (Bupleurum Soothing Liver Powder, Silybin Meglumine Tablets) can reduce the content of ALT, AST, ALP, TBA, and MDA in the serum or liver tissue of the cholestatic liver injury model induced by α-naphthalene isothiocyanate (ANIT), and increase the content of SOD and GSH in serum or liver tissue, which shows that the above drugs have a certain liver protection effect. Among them, the Chinese medicine formula stock solution of the health tea of ​​the present invention (i.e., formula 1) has the same effect of reducing or increasing the above indicators as the positive control drug, and is significantly better than the stock solutions of the other groups of formulas.

[0055] Table 3

[0056]

[0057] The stock solutions of formulas 1-3 and the positive control drug (simvastatin) can reduce the serum TC, TG, and LDLC contents of rats with fatty liver induced by high-fat diet, increase the serum HDLC content, and reduce the liver coefficient, which shows that the above drugs have certain liver protection, blood lipid reduction and anti-fatty liver effects. Among them, the Chinese medicine formula stock solution of the health tea of ​​the present invention (i.e., formula 1) has the same effect of reducing or increasing the above indicators as the positive control drug, and is significantly better than the Chinese medicine stock solutions of the other groups of formulas.

[0058] The health-care tea of ​​the present invention selects multiple ingredients including Pu'er tea, Centella asiatica leaves, gallic acid seeds, dried longan, chrysanthemum, radix scutellariae, dendrobium and jujube, and is obtained by applying traditional Chinese medicine dialectical compatibility, so as to give full play to the effects of various medicines, and all medicines work together to enhance the efficacy. Among them, Centella asiatica leaves, gallic acid seeds and radix scutellariae play an important role in realizing the liver-protecting effect in the health-care tea of ​​the present invention. All ingredients in the formula of the health-care tea of ​​the present invention are indispensable, and the effects of protecting the liver, lowering blood lipids and improving fatty liver are realized together.

[0059] Test Example 2

[0060] Experimental population: The experiment was divided into 40-50 years old group and 50-60 years old group. Each group selected 30 patients with liver damage such as fatty liver and alcoholic liver with similar living habits and living standards.

[0061] Experimental method: Before the experiment, each experimental group was given a liver function test and the test results were recorded. During the experiment, the experimental group was given this product, 1 serving of health tea per day. After 30 days, the experimental group was given a liver function test again, and the results were compared with those before the experiment, and the improvement of liver damage was recorded. During the experiment, each group of subjects was required to maintain a healthy diet and work and rest.

[0062] Experimental results:

[0063] Better improvement: liver damage has been significantly improved, and liver function indicators have been significantly reduced;

[0064] General improvement: liver damage improved slightly and liver function indicators decreased;

[0065] No improvement: There was no improvement in liver damage, and liver function indicators did not decrease or increase.

[0066] Table 4 Results of crowd observation experiment

[0067] Grouping Better improvement General Improvement No improvement Total improvement rate (%) 40-50 years old 17 10 3 90 50-60 years old group 19 10 1 96.7

[0068] The above results show that continuous use of the health tea of ​​the present invention can significantly improve the liver function indicators of patients with liver damage, repair liver damage, and help patients restore liver function. The improvement rate for patients with liver damage can reach 90% or more.

Claims

1. A liver protection health tea, comprising: 20 parts of Pu'er tea, 10 parts of Centella asiatica leaves, 10 parts of gallic acid seeds, 20 parts of dried longans, 10 parts of chrysanthemums, 10 parts of yellow grass, 10 parts of dendrobiums, and 10 parts of jujubes.

2. The liver protection health tea according to claim 1, wherein: The Pu'er tea is Pu'er cooked tea.

3. The liver protection health tea according to claim 1, wherein: The Pu'er tea is obtained by drying the Pu'er tea at 90-120° C. for 20-30 minutes.

4. The liver protection health tea according to claim 1, wherein: The Centella asiatica leaves are dried at 90-120° C. for 20-30 minutes.

5. The liver-protecting health tea according to claim 1, wherein: The gallic acid is obtained by drying at 90-120° C. for 20-30 minutes.

6. The liver-protecting health tea according to claim 1, wherein: The dried longan is prepared by the following method: Fresh longan is dried at 90-120℃ for 24h, the core is removed and the fruit is kept.

7. The liver protection health tea according to claim 1, wherein: The chrysanthemum is prepared by the following method: Fresh chrysanthemum is dried at 90-120℃ for 24h.

8. The liver protection health tea according to claim 1, wherein: The yellow grass is the rhizome of the yellow grass, which is prepared by the following method: The rhizomes of the herb are dried at 90-120°C for 20-30min.

9. The liver-protecting health tea according to claim 1, wherein: The dendrobium is the stem of dendrobium, which is prepared by the following method: The stem of Dendrobium is dried at 90-120°C for 20-30 minutes.

10. The liver-protecting health tea according to claim 1, wherein: The jujube is prepared by the following method: Fresh jujube is dried at 90-120℃ for 24h, pitted and sliced.

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