Bubble cleaning device suitable for plasma sampling tube
By setting up a bubble cleaning device with a through hole cleaning plate and a handle mesh pocket in the plasma sample tube, the problem of inconvenience in bubble removal in the plasma sample is solved, and fast and accurate bubble cleaning is achieved to ensure the reliability of experimental results.
Patent Information
- Application Number
- CN202420606576.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-03-27
- Publication Date
- 2024-12-10
- Estimated Expiration
- 2034-03-27
AI Technical Summary
In medical enzyme-free and nucleic acid testing experiments, a large number of bubbles are generated during the mixing process of plasma samples. Existing methods such as using a sample loading gun or a cotton swab to remove bubbles are not convenient enough, and the sample may be lost or the experimental results may be affected.
A bubble cleaning device including card blocks and cleaning boards is designed to ensure the detection results by setting a cleaning board in the sample tube, using its through-hole structure to quickly remove bubbles and provide handles and mesh bags for additional cleaning of bubbles or fat layers. accuracy.
It realizes rapid clearing of bubbles without changing plasma concentration and capacity, simplifies the operation process, improves the accuracy of detection results, and can withstand high-temperature autoclave sterilization, meeting laboratory requirements.
Smart Images
Figure CN222131061U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of plasma detection auxiliary tools, in particular to a bubble cleaning device suitable for a plasma sampling tube. Background Art
[0002] All medical ELISA and nucleic acid testing laboratories have to perform indoor quality control every day. Indoor quality control products are usually kept in a low-temperature refrigerator. About 30 minutes before the experiment, the quality control products should be taken out of the refrigerator, thawed, inverted or shaken to mix, and then tested together with the samples. During the mixing process, the quality control plasma (clear) will produce a large number of bubbles, most of which will not disappear automatically. In order to ensure the accuracy of the quality control results, staff usually use a pipetting gun or cotton swab to remove the bubbles, but these two methods are very inconvenient and will also result in the loss of some quality control plasma (clear).
[0003] In the imported nucleic acid detection experiment of Gailefu, 4 positive and negative control sample tubes must be taken out of the ultra-low temperature refrigerator before each experiment, melted at room temperature and then mixed. A large number of bubbles will be generated during the mixing process. Most bubbles will not disappear on their own and need to be removed manually by staff. Because the sample control test tubes are all covered with paper labels, it is impossible to directly observe the internal situation of the test tubes, and the sample gun cannot be used to remove bubbles. Staff can only use centrifugation, knocking on the outer wall of the test tube, or using cotton swabs to remove bubbles in the test tube. These methods are very troublesome and generally require repeated operations many times. It is time-consuming, labor-intensive and the effect is not ideal. If the reagent liquid in the sample control tube is only about 1 ml, using too many cotton swabs will significantly reduce the capacity of the control substance, which may affect the experimental results. At the same time, because the inside of the test tube is not easy to observe, once the residual bubbles affect the experiment, it is likely to cause the experiment to fail.
[0004] During the actual experiment, bubbles will be generated when testing sample plasma or the liquid in the reagent tank of various fully automatic testing instruments. These bubbles must be removed before the experiment. Usually, staff use sample guns or cotton swabs to remove bubbles. These methods are not convenient enough and require repeated operations to effectively remove bubbles. In addition, medical cotton swabs have strong water absorption. When removing plasma bubbles, they will also absorb a certain amount of plasma. If the capacity of the sample to be tested is relatively small, it may also cause the sample to be unable to be tested. Utility Model Content
[0005] In order to overcome the above-mentioned defects, the purpose of the utility model is to provide a bubble cleaning device suitable for a plasma sampling tube, which arranges a bubble cleaning device in the sample tube, and uses a cleaning plate to quickly clean the plasma (clear) bubbles in the sample tube without changing the plasma concentration and volume, which makes it easier to meet the subsequent detection needs and ensure the accuracy of the test results.
[0006] In order to achieve the above-mentioned object, the utility model provides a bubble cleaning device suitable for a plasma sampling tube, characterized in that it comprises a plasma sampling tube and a bubble cleaning device;
[0007] The bubble cleaning device includes a card block and a cleaning plate, the card block is provided with a connecting groove matching the plasma sampling tube, the card block is connected to the top of the plasma sampling tube through the connecting groove, the cleaning plate is located in the cavity of the plasma sampling tube, and the two ends of the cleaning plate are respectively fixedly connected to the two card blocks.
[0008] Preferably, a plurality of through holes are evenly distributed on the bottom of the cleaning plate.
[0009] Preferably, the cleaning plate is funnel-shaped, one side of the bottom of the cleaning plate is aligned with the inner wall of the test tube, and the cleaning plate has two layers.
[0010] Preferably, a net bag is provided at the bottom of the cleaning filter, and the net bag is densely covered with a plurality of meshes.
[0011] Preferably, the cleaning plate and the net bag are both made of hard synthetic plastic.
[0012] Preferably, the top of the net bag is connected to the handle via a telescopic rod.
[0013] After adopting the above technical solution, the beneficial technical effects achieved by the utility model are:
[0014] 1. Since a bubble cleaning device is provided at the end of the sample tube, before the experiment, the sample tube cover is rotated to open and removed, and the mixed quality control plasma (clear) is directly poured into the sample tube. The cleaning plate in the bubble cleaning device can quickly remove bubbles without changing the plasma concentration and volume. The filtered quality control sample tube can be directly used for the experiment. Even if the plasma to be tested is divided into several portions, the cleaning plate can be used to block it. At this time, the bubbles will be directly filtered, which is conducive to ensuring the accuracy of the test results.
[0015] 2. Due to the addition of a handle and a net bag at the lower end of the handle, when there is no need to transfer in the plasma sampling tube, the operator can use the handle and the net bag to quickly clean the bubbles or fat layer. The operation is quick and easy, and the bubbles or fat layer are cleaned thoroughly with good results. The net bag and the cleaning plate are both medical synthetic plastics, which can withstand high temperature and high pressure sterilization, can be sterile, free of DNase, RNase, and heat source, meet the laboratory nucleic acid detection and enzyme-immune detection and other experimental requirements, and will not absorb liquids, thereby ensuring the accuracy of the test results. BRIEF DESCRIPTION OF THE DRAWINGS
[0016] Figure 1 This is a reference diagram of one of the usage states of the bubble cleaning device for a plasma sampling tube of the utility model;
[0017] Figure 2 yes Figure 1 Enlarged view of point A in the middle;
[0018] Figure 3 It is a structural schematic diagram of a net bag in a bubble cleaning device suitable for a plasma sampling tube of the utility model;
[0019] In the figure, 1. plasma sampling tube;
[0020] 2. Bubble cleaning device; 21. Block; 22. Connecting groove; 23. Cleaning plate; 24. Through hole;
[0021] 3. Handle; 31. Net bag; DETAILED DESCRIPTION
[0022] In order to make the purpose, technical solutions and advantages of the utility model more clearly understood, the utility model is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the utility model and are not used to limit the utility model.
[0023] See also Figure 1-Figure 3 The utility model provides a bubble cleaning device 2 suitable for a plasma sample tube 1, comprising a plasma sample tube 1 and a bubble cleaning device 2; the bubble cleaning device 2 comprises a clamping block 21 and a cleaning plate 23, the clamping block 21 is provided with a connecting groove 22 matching the plasma sample tube 1, the clamping block 21 is clamped to the top of the plasma sample tube 1 through the connecting groove 22, the cleaning plate 23 is located in the cavity of the plasma sample tube 1, and the two ends of the cleaning plate 23 are respectively fixedly connected to the two clamping blocks 21. A certain amount of samples to be tested are stored inside the plasma sample tube 1. Before testing, the cover at the end of the plasma sample tube 1 needs to be rotated and removed, and then the bubble cleaning device 2 placed in the sterile bag is taken out, the connecting groove 22 of the clamping block 21 is clamped to the end of the plasma sample tube 1, the cleaning plate 23 is placed in the plasma sample tube 1 to a certain depth, and the cleaning plate 23 is slowly moved. Since the bottom of the cleaning plate 23 has a through hole 24, the plasma bubbles can be directly cleaned, especially when a plasma sample is divided into multiple portions, the cleaning plate 23 can be directly used as a filter to directly intercept the bubbles.
[0024] The bottom of the cleaning plate 23 of the utility model is evenly distributed with a plurality of through holes 24. The through holes 24 facilitate better filtering function. Generally, the diameter of the through holes 24 is generally about 1 mm, which can ensure that the plasma flows naturally in a short time to meet the use requirements.
[0025] The cleaning plate 23 of the utility model is in the shape of a funnel, and the bottom of the cleaning plate 23 contacts the inner wall of the sample tube to facilitate the plasma (clear) to flow down along the inner wall of the sample tube, and the cleaning plate 23 is two-layered. The cleaning plate 23 is relatively thin, in the form of a sheet with a thickness of about 1 mm, which is convenient for bending. In actual use, two cleaning plates 23 are generally stacked for use, and the bottom width of the two cleaning plates 23 is slightly larger than the top, so that when used as a funnel, the contact area is larger, so the filtering effect on bubbles will be better.
[0026] The side of one of the blocks 21 of the utility model is provided with a connection hole (not shown in the figure) for fixing the handle 3. The block 21 has a certain thickness, and can be provided with a connection hole or a connection slot for clamping and fixing the handle 3. If the volume of the plasma sample to be tested is small and cannot be divided into multiple portions, the handle 3 and the net bag 31 at the lower end of the handle 3 can be used at this time. The net bag 31 is evenly and densely covered with meshes. Holding the handle 3, the inside of the plasma sampling tube 1 can be directly penetrated to clean the plasma bubbles on the surface. In order to facilitate the adaptation of plasma solutions of various heights, the net bag 31 is connected to the handle 3 through a telescopic rod. The telescopic rod is a prior art and has many applications in the field of fishing rods.
[0027] The cleaning plate 23 and the net bag 31 of the utility model are both made of synthetic plastic. The cleaning plate 23 and the net bag 31 are both non-absorbent, and the synthetic plastic is of good quality, can withstand high temperature and high pressure sterilization, can be sterile, free of DNA enzyme, free of RNA enzyme, and free of heat source, and meet the experimental requirements of laboratory nucleic acid detection and enzyme-free detection. To avoid cross infection, the net bag 31 and the cleaning plate 23 are both disposable medical devices. Generally, the net bag 31 and the cleaning plate 23 can be packaged separately, so that production and processing are more convenient. It can also be packaged together, and the handle 3 of the net bag 31 is directly connected with the card block 21, and can be used separately according to actual conditions.
[0028] Of course, the present invention may have many other embodiments. Without departing from the spirit and essence of the present invention, technicians familiar with the field can make various corresponding changes and deformations based on the present invention, but these corresponding changes and deformations should all fall within the scope of protection of the claims attached to the present invention.
Claims
1. A bubble cleaning device suitable for a plasma sampling tube, characterized in that: Includes plasma sampling tube and bubble cleaning device; The bubble cleaning device includes a card block and a cleaning plate. The card block is provided with a connecting groove adapted to the plasma sampling tube. The card block is connected to the top of the plasma sampling tube through the connecting groove. The cleaning plate is located in the cavity of the plasma sampling tube. The two ends of the cleaning plate are respectively fixedly connected to the two card blocks.
2. The bubble cleaning device suitable for a plasma sampling tube according to claim 1, characterized in that: A plurality of through holes are evenly distributed on the bottom of the cleaning plate.
3. The bubble cleaning device suitable for a plasma sampling tube according to claim 2, characterized in that: The cleaning plate is in the shape of a flat sheet and has two layers.
4. The bubble cleaning device suitable for a plasma sampling tube according to claim 3, characterized in that: The cleaning plate is made of hard synthetic plastic.