Special SPE purification column tube for sample purification

Abstract

The utility model relates to the technical field of SPE (Solid Phase Extraction) purification column tubes, and provides a special SPE purification column tube for sample purification, which comprises a column barrel, a column cover, an insertion component, a first sieve plate, a second sieve plate, a limiting component, a sealing component and a discharge tube, the column barrel comprises an insertion part, a filler filling part, a sieve plate mounting part and a column cover mounting part, the inserting part, the filler filling part, the sieve plate mounting part and the column cover mounting part are of an integrated structure, the inserting part is connected with the inserting assembly, the first sieve plate is arranged in the inserting assembly, the second sieve plate is arranged on the side, close to the column cover mounting part, of the sieve plate mounting part, the column cover mounting part is connected with the column cover, and a limiting assembly is arranged on the side, away from the second sieve plate, of the column cover. According to the utility model, the structure is reasonable, the use is convenient, the use of special tools is avoided, the installation speed is improved, and a stable support can be provided for the sieve plate, so that the sieve plate is kept in a horizontal state, and the filtering effect is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of SPE purification column tubes, in particular to a special SPE purification column tube for sample purification. Background Art

[0002] Solid Phase Extraction (SPE) is the process of using solid adsorbents to adsorb target compounds in liquid samples, separate them from the sample matrix and interfering compounds, and then elute them with eluent or desorb them by heating to achieve the purpose of separating and enriching target compounds. SPE has been widely used and has become a key means of sample pretreatment for chromatographic sample analysis.

[0003] As disclosed in application number: CN201620529614.3, a special SPE purification column tube for sample purification includes a column barrel, one end of the column barrel is provided with a discharge pipe, the column barrel is a hollow structure, a first sieve plate is provided at the bottom of the inner cavity of the column barrel, a second sieve plate is provided on the side of the first sieve plate away from the bottom of the column barrel, a packing layer is provided between the second sieve plate and the first sieve plate, a column cover is provided on the side of the second sieve plate away from the first sieve plate, and a limit opening is provided at one end of the column barrel away from the discharge pipe.

[0004] However, when using the above device, the first sieve plate needs to be loaded into the bottom of the column barrel using a special tool, which is inconvenient. Moreover, when the second sieve plate is loaded into the column barrel, it is difficult to ensure that the second sieve plate is in a horizontal state, resulting in poor filtering effect. Utility Model Content

[0005] In order to solve the problem that the existing device needs to use special tools to load the first sieve plate to the bottom of the column barrel when in use, which is inconvenient, and it is difficult to ensure the second sieve plate is in a horizontal state when it is loaded into the column barrel, resulting in poor filtering effect, the utility model provides a SPE purification column tube dedicated to sample purification to solve this problem.

[0006] In order to achieve the above object, the utility model provides the following technical solutions:

[0007] A special SPE purification column tube for sample purification comprises: a column barrel, a column cover, a plug-in assembly, a first sieve plate, a second sieve plate, a limiting assembly, a sealing assembly and a discharge pipe, wherein the column barrel comprises: a plug-in portion, a filler filling portion, a sieve plate mounting portion and a column cover mounting portion, the plug-in portion, the filler filling portion, the sieve plate mounting portion and the column cover mounting portion are an integrated structure, the plug-in portion is connected to the plug-in assembly, the first sieve plate is arranged in the plug-in assembly, the second sieve plate is arranged on a side of the sieve plate mounting portion close to the column cover mounting portion, the column cover mounting portion is connected to the column cover, a limiting assembly is arranged on a side of the column cover away from the second sieve plate, the sealing assembly is mounted on the limiting assembly, and the discharge pipe is connected to the plug-in assembly.

[0008] Preferably, sieve holes are provided on the sieve plate mounting portion.

[0009] Preferably, the plug-in assembly comprises: a plug-in body, an anti-slip ring and a sealing ring, the anti-slip ring is arranged on the outside of the plug-in body, the plug-in body is clamped with the plug-in part through the anti-slip ring, and a sealing ring is arranged between the plug-in body and the column barrel.

[0010] Preferably, the plug-in body includes: a first sieve plate mounting portion and a discharge pipe mounting portion, the first sieve plate mounting portion and the discharge pipe mounting portion are an integrated structure, a first sieve plate is arranged in the first sieve plate mounting portion, the first sieve plate mounting portion cooperates with the plug-in portion to fix the first sieve plate, an anti-slip ring is arranged on the outside of the first sieve plate mounting portion, a sealing ring is arranged between the first sieve plate mounting portion and the plug-in portion, and the discharge pipe mounting portion is fixedly connected to the discharge pipe.

[0011] Preferably, the column cover is clamped with the column cover mounting portion through a column cover anti-slip ring.

[0012] Preferably, the limit assembly comprises: a limit seat and a limit anti-drop ring, the limit seat is fixedly connected to the column cover, a limit anti-drop ring is arranged on the outer side of the limit seat, and a sealing assembly is arranged inside the limit seat.

[0013] Preferably, the sealing assembly comprises: a sealing platform, a connecting rod and a sealing bracket, the sealing platform is fixedly connected to the sealing bracket via the connecting rod, and the sealing bracket is arranged on the inner wall of the limiting seat.

[0014] The advantages of the utility model are: by providing a plug-in component and a plug-in part on the column barrel, the utility model can first install the first sieve plate on the plug-in component, and then clamp the plug-in component with the plug-in part on the column barrel, thereby avoiding the use of special tools and improving the installation speed. By providing the sieve plate mounting part compared to the filler support, a stable support can be provided for the second sieve plate, thereby keeping the second sieve plate in a horizontal state, avoiding poor filtering effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] The accompanying drawings constituting a part of the present invention are used to provide a further understanding of the present invention. The illustrative embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an improper limitation on the present invention. In the accompanying drawings:

[0016] Figure 1 It is a structural schematic diagram of the utility model;

[0017] Figure 2 It is a cross-sectional view of the utility model;

[0018] Figure 3 It is a cross-sectional view of the column barrel of the utility model;

[0019] Figure 4 This is the front view of the screen plate installation part of the utility model;

[0020] Figure 5 It is a structural schematic diagram of the plug-in assembly of the utility model;

[0021] Figure 6 It is a structural schematic diagram of the plug-in body of the utility model;

[0022] Figure 7 It is a structural schematic diagram of the column cover of the utility model;

[0023] Figure 8 It is a structural schematic diagram of the sealing component of the utility model.

[0024] Description of reference numerals:

[0025] 1. Column barrel; 2. Column cover; 3. Plug-in assembly; 4. First sieve plate; 5. Second sieve plate; 6. Limit assembly; 7. Sealing assembly; 8. Discharge pipe; 11. Plug-in part; 12. Filling part; 13. Sieve plate mounting part; 14. Column cover mounting part; 131. Sieve hole; 31. Plug-in body; 32. Anti-slip ring; 33. Sealing ring; 311. First sieve plate mounting part; 312. Discharge pipe mounting part; 21. Column cover anti-slip ring; 61. Limit seat; 62. Limit anti-slip ring; 71. Sealing table; 72. Connecting rod; 73. Sealing bracket. DETAILED DESCRIPTION

[0026] It should be noted that, in the absence of conflict, the embodiments of the present invention and the features in the embodiments can be combined with each other.

[0027] In the description of the present utility model, it should be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present utility model. In addition, the terms "first", "second", etc. are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, features defined as "first", "second", etc. may explicitly or implicitly include one or more of the features. In the description of the present utility model, unless otherwise specified, "multiple" means two or more.

[0028] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood by specific circumstances.

[0029] Embodiment 1, combined with Figure 1 , Figure 2 and Figure 3 To explain:

[0030] A special SPE purification column for sample purification comprises: a column barrel 1, a column cover 2, a plug-in assembly 3, a first sieve plate 4, a second sieve plate 5, a limiting assembly 6, a sealing assembly 7 and a discharge pipe 8. The column barrel 1 comprises: a plug-in portion 11, a filler filling portion 12, a sieve plate mounting portion 13 and a column cover mounting portion 14. The plug-in portion 11, the filler filling portion 12, the sieve plate mounting portion 13 and the column cover mounting portion 14 are an integrated structure. The plug-in portion 11 is connected to the plug-in assembly 3, the first sieve plate 4 is arranged in the plug-in assembly 3, the second sieve plate 5 is arranged on a side of the sieve plate mounting portion 13 close to the column cover mounting portion 14, the column cover mounting portion 14 is connected to the column cover 2, the limiting assembly 6 is arranged on the side of the column cover 2 away from the second sieve plate 5, the sealing assembly 7 is installed on the limiting assembly 6, and the discharge pipe 8 is connected to the plug-in assembly 3.

[0031] In this way, by setting the plug-in component 3 and the plug-in part 11 on the column barrel 1, the first sieve plate 4 can be installed on the plug-in component 3 first, and then the plug-in component 3 can be clamped with the plug-in part 11 on the column barrel 1, thereby avoiding the use of special tools and increasing the installation speed. By setting the sieve plate mounting part 13, a stable support can be provided for the second sieve plate 5 compared to the filler support, thereby keeping the second sieve plate 5 in a horizontal state, avoiding poor filtering effect.

[0032] Embodiment 2, based on embodiment 1, combined with Figure 4 To explain:

[0033] The sieve plate mounting portion 13 is provided with sieve holes 131. Such arrangement can ensure smooth flow of liquid.

[0034] Embodiment 3, based on embodiment 2, combined with Figure 5 To explain:

[0035] The plug assembly 3 includes: a plug body 31, an anti-drop ring 32 and a sealing ring 33. The anti-drop ring 32 is arranged outside the plug body 31. The plug body 31 is clamped with the plug part 11 through the anti-drop ring 32. The sealing ring 33 is arranged between the plug body 31 and the column barrel 1. Multiple groups of anti-drop rings 32 can be provided.

[0036] With such arrangement, the anti-drop ring 32 can improve the connection strength between the plug-in body 31 and the plug-in portion 11 , and the sealing performance between the plug-in body 31 and the column barrel 1 can be improved by arranging the sealing ring 33 .

[0037] Embodiment 4, based on embodiment 3, combined with Figure 6 To explain:

[0038] The plug-in body 31 includes: a first sieve plate mounting portion 311 and a discharge pipe mounting portion 312, the first sieve plate mounting portion 311 and the discharge pipe mounting portion 312 are an integrated structure, a first sieve plate 4 is arranged in the first sieve plate mounting portion 311, the first sieve plate mounting portion 311 cooperates with the plug-in portion 11 to fix the first sieve plate 4, an anti-slip ring 32 is arranged on the outside of the first sieve plate mounting portion 311, a sealing ring 33 is arranged between the first sieve plate mounting portion 311 and the plug-in portion 11, and the discharge pipe mounting portion 312 is fixedly connected to the discharge pipe 8.

[0039] In this arrangement, the first sieve plate mounting portion 311 is used to place the first sieve plate 4. The first sieve plate mounting portion 311 and the plug-in portion 11 can be used in conjunction to fix the first sieve plate 4 on the first sieve plate mounting portion 311. The discharge pipe mounting portion 312 is provided to facilitate connection with the discharge pipe 8.

[0040] Embodiment 5, based on embodiment 4, combined with Figure 7 To explain:

[0041] The column cover 2 is clamped with the column cover mounting portion 14 via a column cover anti-slip ring 21 .

[0042] This arrangement improves the connection strength.

[0043] The limiting assembly 6 comprises: a limiting seat 61 and a limiting anti-slip ring 62 . The limiting seat 61 is fixedly connected to the column cover 2 . The limiting anti-slip ring 62 is arranged outside the limiting seat 61 . The sealing assembly 7 is arranged inside the limiting seat 61 .

[0044] Embodiment 6, based on embodiment 5, combined with Figure 8 To explain:

[0045] The sealing assembly 7 includes: a sealing platform 71 , a connecting rod 72 and a sealing bracket 73 . The sealing platform 71 is fixedly connected to the sealing bracket 73 via the connecting rod 72 . The sealing bracket 73 is arranged on the inner wall of the limiting seat 61 .

[0046] A sealing assembly 7 is added to the bottom of the column cover 2 to seal the sample to avoid backflow due to high pressure.

[0047] Working principle of the utility model: when the utility model is in use, the first sieve plate 4 is first placed on the plug-in component 3, and then the plug-in component 3 is inserted into the plug-in part 11 of the column barrel 1. The plug-in part 11 presses the sealing ring 33 and the first sieve plate 4, which can not only fix the first sieve plate 4 but also ensure its sealing performance. Then the discharge pipe 8 is fixed to the other end of the plug-in component 3. After the installation is completed, the second sieve plate 5 is placed on the sieve plate mounting part 13. Since the sieve plate mounting part 13 is a rigid structure and is horizontally arranged, under the pressure of the column cover 2, the second sieve plate 5 and the sieve plate mounting part 13 remain horizontally arranged. Compared with the flexible material of the seasoning, the tilted arrangement of the second sieve plate 5 is prevented. Then the sealing component 7 is fixed on the limiting component (the patent cited in the background technology has been disclosed). The utility model has a reasonable structure and is easy to use. It avoids the use of special tools and increases the installation speed. It can also provide a stable support for the second sieve plate 5, thereby keeping the second sieve plate 5 in a horizontal state to avoid poor filtering effect.

[0048] For those skilled in the art, the present invention is not limited to the details of the above exemplary embodiments, and can be implemented in other specific forms without departing from the spirit or basic features of the present invention; therefore, no matter from which point of view, the embodiments should be regarded as exemplary and non-restrictive, and the scope of the present invention is defined by the appended claims rather than the above description, so it is intended to include all changes within the meaning and scope of the equivalent elements of the claims. Any figure mark in the claims should not be regarded as limiting the claims involved.

[0049] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any minor modifications, equivalent substitutions and improvements made to the above embodiments based on the technical essence of the present invention should be included in the protection scope of the technical solution of the present invention.

Claims

1. A special SPE purification column for sample purification, characterized in that: include: A column barrel (1), a column cover (2), a plug-in assembly (3), a first sieve plate (4), a second sieve plate (5), a limit assembly (6), a sealing assembly (7) and a discharge pipe (8), wherein the column barrel (1) comprises: a plug-in portion (11), a filler filling portion (12), a sieve plate mounting portion (13) and a column cover mounting portion (14), wherein the plug-in portion (11), the filler filling portion (12), the sieve plate mounting portion (13) and the column cover mounting portion (14) are an integrated structure, and the The plug-in portion (11) is connected to the plug-in assembly (3), the first sieve plate (4) is arranged in the plug-in assembly (3), the second sieve plate (5) is arranged on a side of the sieve plate mounting portion (13) close to the column cover mounting portion (14), the column cover mounting portion (14) is connected to the column cover (2), a limit assembly (6) is arranged on a side of the column cover (2) away from the second sieve plate (5), the sealing assembly (7) is installed on the limit assembly (6), and the discharge pipe (8) is connected to the plug-in assembly (3).

2. The SPE purification column tube for sample purification according to claim 1, characterized in that: The sieve plate mounting portion (13) is provided with sieve holes (131).

3. A special SPE purification column tube for sample purification according to claim 1, characterized in that, The plug-in assembly (3) comprises: a plug-in body (31), an anti-slip ring (32) and a sealing ring (33); the anti-slip ring (32) is arranged on the outside of the plug-in body (31); the plug-in body (31) is clamped with the plug-in portion (11) via the anti-slip ring (32); and a sealing ring (33) is arranged between the plug-in body (31) and the column barrel (1).

4. A special SPE purification column tube for sample purification according to claim 3, characterized in that, The plug-in body (31) comprises: a first sieve plate mounting portion (311) and a discharge pipe mounting portion (312); the first sieve plate mounting portion (311) and the discharge pipe mounting portion (312) are an integrated structure; a first sieve plate (4) is arranged in the first sieve plate mounting portion (311); the first sieve plate mounting portion (311) cooperates with the plug-in portion (11) to fix the first sieve plate (4); an anti-slip ring (32) is arranged on the outside of the first sieve plate mounting portion (311); a sealing ring (33) is arranged between the first sieve plate mounting portion (311) and the plug-in portion (11); and the discharge pipe mounting portion (312) is fixedly connected to the discharge pipe (8).

5. The SPE purification column tube for sample purification according to claim 1, characterized in that: The column cover (2) is clamped with the column cover mounting portion (14) via a column cover anti-slip ring (21).

6. The SPE purification column tube for sample purification according to claim 1, characterized in that: The limiting assembly (6) comprises: a limiting seat (61) and a limiting anti-slip ring (62); the limiting seat (61) is fixedly connected to the column cover (2); a limiting anti-slip ring (62) is arranged outside the limiting seat (61); and a sealing assembly (7) is arranged inside the limiting seat (61).

7. A special SPE purification column tube for sample purification according to claim 6, characterized in that: The sealing assembly (7) comprises: a sealing platform (71), a connecting rod (72) and a sealing bracket (73); the sealing platform (71) is fixedly connected to the sealing bracket (73) via the connecting rod (72); and the sealing bracket (73) is arranged on the inner wall of the limiting seat (61).

Images